BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0026.p (519 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_229499.1| conserved hypothetical protein [Thermotoga mari... 196 2e-48 ref|NP_864574.1| conserved hypothetical protein-putative phospho... 181 3e-44 ref|ZP_00061795.1| COG2206: HD-GYP domain [Clostridium thermocel... 181 3e-44 ref|NP_621747.1| Response regulators consisting of a CheY-like r... 167 6e-40 ref|ZP_00059827.1| COG2206: HD-GYP domain [Clostridium thermocel... 164 4e-39 >ref|NP_229499.1| conserved hypothetical protein [Thermotoga maritima] pir||E72220 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gb|AAD36766.1| conserved hypothetical protein [Thermotoga maritima] Length = 558 Score = 196 bits (497), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 100/211 (47%), Positives = 134/211 (63%), Gaps = 9/211 (4%) Query: 300 VAGFNMMVRGLQ---AREQQSRQLLDSYFTTL---AVALDARDPYTAGHSLRVAEYSVII 353 ++ MM R L +R R+L ++F T+ + A++ +DPYT+GHSLRVA+YS I Sbjct: 349 LSSLKMMARILAIFFSRLSLYRKLRKTFFQTIEAFSYAVELKDPYTSGHSLRVADYSQEI 408 Query: 354 GQLAGLTGQQLDNLRKSALLHDIGKIGVRDSVLFKXXXXXXXXFDQIKSHPVLGENILRQ 413 + GL Q ++ +R +A+LHDIGKIGV+ ++L K ++++K HP LGE ++ + Sbjct: 409 ARRKGLPDQVVERIRIAAVLHDIGKIGVKGAILNKTSKLTKEEYEEVKKHPELGEKLISK 468 Query: 414 IEPEEKMAPYLGGVRSHHERYDGKGYPDGLAGTAIPLHGRIIAVADAYDAMTSDRPYRKG 473 IE +A VR HHE Y G+GYPDGL G IPL RIIAVADA+DAMTSDRPYRK Sbjct: 469 IEDFSDIAKI---VRHHHEWYSGQGYPDGLRGEEIPLESRIIAVADAFDAMTSDRPYRKA 525 Query: 474 MDHDRALAILEQGRGTQWDPEFAGLFLAYFG 504 MD AL IL + G QWDPE + L YF Sbjct: 526 MDRKTALEILRRNEGPQWDPEILKIALDYFS 556 >ref|NP_864574.1| conserved hypothetical protein-putative phosphohydrolase [Pirellula sp. 1] emb|CAD72255.1| conserved hypothetical protein-putative phosphohydrolase [Pirellula sp.] Length = 432 Score = 181 bits (460), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 103/228 (45%), Positives = 136/228 (59%), Gaps = 14/228 (6%) Query: 283 GRLLQVQDEYSDEFS----KLVAGFNMM-----VRGLQAREQQSRQLLDSYFTTLAVALD 333 GR++ ++ EF+ LV MM V Q E QS +L+ +LA ALD Sbjct: 190 GRMISIRTLDQPEFTTVDIDLVRSVLMMLSMHLVNQRQYIEMQS--MLEGMVRSLASALD 247 Query: 334 ARDPYTAGHSLRVAEYSVIIGQLAGLTGQQLDNLRKSALLHDIGKIGVRDSVLFKXXXXX 393 A+D YT GHS RVA+ +V + + G+T Q D+L+ + +LHDIGKIG+ DSVL K Sbjct: 248 AKDAYTCGHSSRVADLAVALSRRLGMTQQDSDSLQLAGILHDIGKIGIDDSVLKKPGALT 307 Query: 394 XXXFDQIKSHPVLGENILRQIEPEEKMAPYLGGVRSHHERYDGKGYPDGLAGTAIPLHGR 453 FDQIK HPVLG IL+ I P + P VR HHE +DG+GYPDGL+G IP + Sbjct: 308 DEEFDQIKRHPVLGYEILKGIRPFRHILP---AVRHHHESWDGRGYPDGLSGDNIPRAAQ 364 Query: 454 IIAVADAYDAMTSDRPYRKGMDHDRALAILEQGRGTQWDPEFAGLFLA 501 I+AVAD++DAM SDRPYR+GM D+ I +GRG QW + L+ Sbjct: 365 ILAVADSFDAMVSDRPYRRGMPLDKVRKIFREGRGKQWASDVVDALLS 412 >ref|ZP_00061795.1| COG2206: HD-GYP domain [Clostridium thermocellum ATCC 27405] Length = 465 Score = 181 bits (460), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 86/174 (49%), Positives = 116/174 (66%), Gaps = 3/174 (1%) Query: 327 TLAVALDARDPYTAGHSLRVAEYSVIIGQLAGLTGQQLDNLRKSALLHDIGKIGVRDSVL 386 LA +++A+DPYT GH RV E S + + L+ +++ +LR +A+LHDIGKIG+ S+L Sbjct: 286 CLANSIEAKDPYTRGHCQRVMEISCELARAMKLSEEEIKDLRYAAILHDIGKIGISASIL 345 Query: 387 FKXXXXXXXXFDQIKSHPVLGENILRQIEPEEKMAPYLGGVRSHHERYDGKGYPDGLAGT 446 K F++IK HP++ NIL+ +E + L G+ HHERYDGKGYP GL G Sbjct: 346 NKQGKLTDEEFEEIKKHPIIAYNILKDVEF---LKNGLNGILQHHERYDGKGYPYGLKGE 402 Query: 447 AIPLHGRIIAVADAYDAMTSDRPYRKGMDHDRALAILEQGRGTQWDPEFAGLFL 500 I + RI+ VADA+DAMTSDRPYRKGMD AL +++ RGTQ+DPE A L L Sbjct: 403 EICIFARIMCVADAFDAMTSDRPYRKGMDMKSALEEIKRCRGTQFDPEIADLLL 456 >ref|NP_621747.1| Response regulators consisting of a CheY-like receiver domain and an HD-GYP domain [Thermoanaerobacter tengcongensis] gb|AAM23351.1| Response regulators consisting of a CheY-like receiver domain and an HD-GYP domain [Thermoanaerobacter tengcongensis] Length = 632 Score = 167 bits (423), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 79/177 (44%), Positives = 118/177 (66%), Gaps = 5/177 (2%) Query: 328 LAVALDARDPYTAGHSLRVAEYSVIIGQLAGLTGQQLDNLRKSALLHDIGKIGVRDSVLF 387 LA A++A+D +T GHS+RV++Y+ +IG+ G + ++++ LR + +LHDIGKIG+RDS+L Sbjct: 441 LAYAIEAKDIHTKGHSMRVSQYAALIGEYMGFSREKVEQLRIAGILHDIGKIGIRDSILL 500 Query: 388 KXXXXXXXXFDQIKSHPVLGENILRQIE-PEEKMAPYLGGVRSHHERYDGKGYPDGLAGT 446 K ++ +K HP + IL I+ P+E L + HHERYDGKGYP GL G Sbjct: 501 KEGKLTQQEYEAMKLHPEIARKILAPIDLPKE----ILEAIAKHHERYDGKGYPYGLKGE 556 Query: 447 AIPLHGRIIAVADAYDAMTSDRPYRKGMDHDRALAILEQGRGTQWDPEFAGLFLAYF 503 IP+ I+ VADA+DAMTSDR YRKGM + A+ + + +GTQ+ PE +F++ + Sbjct: 557 EIPIEAAILGVADAFDAMTSDRSYRKGMSIEEAVNEVLRNKGTQFHPEVVDVFISIY 613 >ref|ZP_00059827.1| COG2206: HD-GYP domain [Clostridium thermocellum ATCC 27405] Length = 505 Score = 164 bits (416), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 84/193 (43%), Positives = 114/193 (59%), Gaps = 5/193 (2%) Query: 310 LQAREQQS--RQLLDSYFTTLAVALDARDPYTAGHSLRVAEYSVIIGQLAGLTGQQLDNL 367 +Q R+ S Q L F L + A+D YT GH RVA Y+V+I + GL+ +++ + Sbjct: 308 MQIRKNISSDHQQLIGIFKGLLSTISAKDKYTHGHCERVAAYAVLIAEAMGLSAKEISTI 367 Query: 368 RKSALLHDIGKIGVRDSVLFKXXXXXXXXFDQIKSHPVLGENILRQIEPEEKMAPYLGGV 427 + +ALLHDIGKI + +L K ++ HP+ ENIL + +K+ Y V Sbjct: 368 QCAALLHDIGKIEMPRHILNKKEELTEEEIKYLRQHPIYSENILEPLADMDKLTDY---V 424 Query: 428 RSHHERYDGKGYPDGLAGTAIPLHGRIIAVADAYDAMTSDRPYRKGMDHDRALAILEQGR 487 R HHERYDGKGYPDGL G I L RI+ VAD++DAM SDRPY K M + A LE+ Sbjct: 425 RHHHERYDGKGYPDGLKGKEISLGARILCVADSFDAMVSDRPYSKSMSKEDAFKELEKNA 484 Query: 488 GTQWDPEFAGLFL 500 GTQ+DPE +F+ Sbjct: 485 GTQFDPEIVEIFI 497 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.326 0.142 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 690,110,025 Number of extensions: 26506886 Number of successful extensions: 92427 Number of sequences better than 1.0e-05: 390 Number of HSP's gapped: 92078 Number of HSP's successfully gapped: 396 Length of query: 519 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 389 Effective length of database: 404,274,708 Effective search space: 157262861412 Effective search space used: 157262861412 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 128 (53.9 bits)