BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0015.p (340 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242794.1| transcriptional regulator (LacI family) [Bacill... 241 1e-62 ref|NP_622450.1| Transcriptional regulator [Thermoanaerobacter t... 219 7e-56 ref|NP_244559.1| transcriptional regulator [Bacillus halodurans]... 202 1e-50 gb|EAI90168.1| unknown [environmental sequence] 195 1e-48 ref|NP_245484.1| PurR [Pasteurella multocida] >gi|37999776|sp|Q9... 195 1e-48 >ref|NP_242794.1| transcriptional regulator (LacI family) [Bacillus halodurans] pir||H83890 transcription regulator (LacI family) BH1928 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05647.1| transcriptional regulator (LacI family) [Bacillus halodurans] Length = 335 Score = 241 bits (616), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 132/331 (39%), Positives = 193/331 (58%), Gaps = 3/331 (0%) Query: 5 IKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLIG 64 I IA+ G S++TVSK++NNY+DVS+K +K+VM+ + + GY PS+SA+ L TKKS IG Sbjct: 4 IYDIAKKTGYSITTVSKVLNNYTDVSDKARKKVMDAVTEMGYFPSSSARMLTTKKSWTIG 63 Query: 65 VIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISSGDYYSRCLHFNVDGC 124 V+F + HPFF V+ FKK + GYDL+F SN+ + Y + VDG Sbjct: 64 VVFVESAGIGMEHPFFSSVIENFKKNVERFGYDLLFASNQIGNEAKTYLEHFRYRGVDGI 123 Query: 125 VIISGQKMEPAIRDLDMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGHREL 184 V++ +P + L + IP + +DL+ +G S V SDN + V++ LGHR + Sbjct: 124 VVVCSLLNDPEVEKLMKADIPSVVIDLDSKG--SSAVYSDNEYGSELAVDYLVSLGHRSI 181 Query: 185 GFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLESGSMP 244 I + QR GF A++ L+++ + V G F G AM LL + P Sbjct: 182 AHISGDQGLFVGVQRLKGFKDAIQKLNLSISDEYIVDGGFFTYEGGQRAMEALLRNRVRP 241 Query: 245 QAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERLGVL 304 AV+AA DL+ALGAI +++ GL +PED +I+G DDI+ +YT+P LTTIRQN + +G Sbjct: 242 TAVYAAGDLMALGAIDTIRKHGLSVPEDFSIVGFDDIQMIRYTAPALTTIRQNTDLIGKT 301 Query: 305 AAHMLYDLIN-NQSDGGSFVVEPALIVRESC 334 AA++L D IN N+ S + LI R+SC Sbjct: 302 AANLLLDQINENEKQSLSVKIPVTLIERDSC 332 >ref|NP_622450.1| Transcriptional regulator [Thermoanaerobacter tengcongensis] gb|AAM24054.1| Transcriptional regulator [Thermoanaerobacter tengcongensis] Length = 336 Score = 219 bits (558), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 120/335 (35%), Positives = 191/335 (57%), Gaps = 3/335 (0%) Query: 1 MQLNIKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKS 60 M + IK IA+ AGVSV+TVS+ +N Y DVSE+T+ ++ +I E+ Y+P++ A+ L T K+ Sbjct: 1 MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKT 60 Query: 61 SLIGVIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISSGDYYSR-CLHF 119 IG++ + + HPFF+EVL K + YDLI F+ + Y + C Sbjct: 61 QTIGMVVSELIKPGVYHPFFLEVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDR 120 Query: 120 NVDGCVIISGQKMEPAIRDLDMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLL 179 V+G ++ + +P I ++ + IP + +D+ + K GYV SDNVQ A + + L Sbjct: 121 KVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVGYVSSDNVQAAFEATSYLIKL 180 Query: 180 GHRELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLE 239 GH+ +GFI D+ +S +R G+ KA+E + + + DF + GY A + L+ Sbjct: 181 GHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFA-DFTQEGGYNAFKTLIF 239 Query: 240 SGSMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKE 299 A+F ASDL+A+G+ RA K+ G+RIPED++++G DDIE +P LTTIRQ+ Sbjct: 240 EHPEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTF 299 Query: 300 RLGVLAAHMLYDLINNQSDGGSFVVEPALIVRESC 334 ++G AA L +I + V+ L+VR+S Sbjct: 300 KMGYTAAKHLLAIIRGEKP-QHIVIPHKLVVRDSA 333 >ref|NP_244559.1| transcriptional regulator [Bacillus halodurans] pir||D84111 transcription regulator BH3692 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07411.1| transcriptional regulator [Bacillus halodurans] Length = 337 Score = 202 bits (514), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 121/336 (36%), Positives = 191/336 (56%), Gaps = 10/336 (2%) Query: 5 IKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLIG 64 IK IA++AGVSV+TVS+ +N YSDV+EKT+K++ +I + YSP+ A++L +S IG Sbjct: 4 IKDIAKVAGVSVTTVSRALNGYSDVNEKTRKKIKDIANELKYSPNVMARSLVMNRSKTIG 63 Query: 65 VIFAGELNVEFTHPFFV-EVLNAFKKQMGVLGYDLIFF----SNEKFISSGDYYSRCLHF 119 ++ + E++ E F EVL + YD+I F S +K S Y C Sbjct: 64 LLVS-EISREGAKDNFTFEVLCGINDRASESDYDIILFNTNTSKQKLKS---YTQLCRER 119 Query: 120 NVDGCVIISGQKMEPAIRDLDMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLL 179 VDG ++ +K +P + ++ S IPC+ VD+ + G+ YV +DNV A K VE Sbjct: 120 CVDGVILQGIKKEDPYLEEVIESDIPCVMVDIPITGESVSYVTTDNVDGAKKAVETLIDF 179 Query: 180 GHRELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLE 239 GHR++ + + +S +R+ G+ +A++ G+ L W ++G+ F E + L+ Sbjct: 180 GHRKIAMMNGHERAYVSGKRKLGYEQALQEAGIPLQEEWVLNGE-FSEQVAEKEAYQFLQ 238 Query: 240 SGSMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKE 299 S A F ASDL+ALG ++A K LR+PE +++IG DDI +YTSP LTT+ QNK Sbjct: 239 KHSDVTAFFCASDLMALGVMKAAKLLNLRLPEQLSVIGFDDILLAQYTSPPLTTVAQNKY 298 Query: 300 RLGVLAAHMLYDLINNQSDGGSFVVEPALIVRESCG 335 ++G AA +L D + + +++ LI+RES Sbjct: 299 QMGYAAAGLLIDRLRMKEVPPFHMLDNELIIRESVA 334 >gb|EAI90168.1| unknown [environmental sequence] Length = 334 Score = 195 bits (495), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 113/337 (33%), Positives = 183/337 (54%), Gaps = 9/337 (2%) Query: 4 NIKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLI 63 NIK++A +AGVS +TVS +IN V+E+T++RV + + Y+PS A++L K+++ I Sbjct: 3 NIKEVAALAGVSTTTVSHVINETRFVAEETRERVFAAMRELNYAPSLVARSLKVKETNSI 62 Query: 64 GVIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISSG-DYYSRCLHFNVD 122 G++ N PFF EV+ ++ GY+L+ + E + Y L VD Sbjct: 63 GMLVTTSSN-----PFFAEVVRGVERYCFEQGYNLMLGNTEGQAETALSYLKMMLRKRVD 117 Query: 123 GCVIISGQKMEPAIRDLD-MSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGH 181 G +I+ + + LD + S+P + +D + + ++ + H LGH Sbjct: 118 GLLIMCSEGQQEVFNQLDWLKSLPVVVMDWGMESADVDLIADNSHRGGYLATRHLLGLGH 177 Query: 182 RELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLESG 241 +G I +NQR+AGF +A++ GLT+N W GD F +SG+ AM RLL Sbjct: 178 TAIGCITGPHSRAPANQRQAGFEQAMQEAGLTVNPEWVQEGD-FDCASGHQAMTRLLALP 236 Query: 242 SMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERL 301 P A+F +D++A+GAI A + GL IP D++I+G D++ ++ SP LTT+ Q KE L Sbjct: 237 ERPTALFVCNDMMAMGAISAAHQAGLVIPRDLSIVGYDNVALAEFMSPPLTTVNQPKEEL 296 Query: 302 GVLAAHMLYDLINNQSDGGSFV-VEPALIVRESCGSK 337 G LA L IN ++ + V+P L++R+SC + Sbjct: 297 GRLAVTRLLARINGEAVADHLITVDPDLVIRDSCAPR 333 >ref|NP_245484.1| PurR [Pasteurella multocida] sp|Q9CN88|PURR_PASMU HTH-type transcriptional repressor purR (Purine nucleotide synthesis repressor) gb|AAK02631.1| PurR [Pasteurella multocida] Length = 334 Score = 195 bits (495), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 109/338 (32%), Positives = 191/338 (56%), Gaps = 11/338 (3%) Query: 5 IKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLIG 64 IK +A+MAGVS +TVS +IN V+ +T+K V++ I++ YSPS A++L + IG Sbjct: 4 IKDVAKMAGVSTTTVSHVINKTRFVAAETEKLVLQAIQELNYSPSAVARSLKVNTTKSIG 63 Query: 65 VIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISS-GDYYSRCLHFNVDG 123 +I P+F E+++A ++ GY L + + + ++ + VDG Sbjct: 64 MIVTSS-----EAPYFAEIIHAVEEHCYRQGYSLFLCNTQNNVEKIKNHLEMLIKKRVDG 118 Query: 124 CVIISGQKMEPAIRDL-DMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGHR 182 +++ + + ++ L + +S+P + +D K + + + + ++ GH+ Sbjct: 119 ILVMCAEYTQDSLDLLANFTSLPLVVMDWGPDNKHTDIIQDHSFEGGYLATKYLIDHGHK 178 Query: 183 ELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESS-GYTAMRRLLESG 241 ++G I + R GF+KA+ GL +N +W + G FFE GY M ++L Sbjct: 179 DIGIIAGELTKTTAKTRYEGFIKAMNEAGLKINPDWVMEG--FFEPEDGYECMNKILAQD 236 Query: 242 SMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERL 301 ++P AVF +D++ALGAI A+ E+GLR+PED++IIG D+I A ++ SP LTTI Q+K RL Sbjct: 237 TLPTAVFCCNDVMALGAISAIGEKGLRVPEDISIIGYDNIHASRFYSPPLTTIHQSKSRL 296 Query: 302 GVLAAHMLYDLINNQSDGGSFV-VEPALIVRESCGSKL 338 G A +L++ IN +S+ + + + P L++R+S S+L Sbjct: 297 GARAVTLLFERINEKSEERAVIEMHPELVIRKSVKSRL 334 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 474,147,732 Number of extensions: 19152093 Number of successful extensions: 54742 Number of sequences better than 1.0e-05: 1203 Number of HSP's gapped: 53037 Number of HSP's successfully gapped: 1222 Length of query: 340 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 214 Effective length of database: 415,135,104 Effective search space: 88838912256 Effective search space used: 88838912256 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 126 (53.1 bits)