BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0005.p (171 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_979918.1| anaerobic ribonucleoside-triphosphate reductase... 142 2e-33 ref|NP_810912.1| anaerobic ribonucleoside-triphosphate reductase... 140 9e-33 ref|NP_357779.1| NrdD activating enzyme, generating glycyl radic... 140 1e-32 ref|ZP_00046951.1| COG0602: Organic radical activating enzymes [... 140 1e-32 gb|AAD00216.1| anaerobic ribonucleotide reductase activator prot... 140 1e-32 >ref|NP_979918.1| anaerobic ribonucleoside-triphosphate reductase activating protein [Bacillus cereus ATCC 10987] gb|AAS42526.1| anaerobic ribonucleoside-triphosphate reductase activating protein [Bacillus cereus ATCC 10987] Length = 150 Score = 142 bits (359), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 70/155 (45%), Positives = 100/155 (64%), Gaps = 6/155 (3%) Query: 1 MNICGYYPESINEGEGMRAVLFLSGCRHRCPGCFNPKTWNFNYGEPFTLERQREIIAEMA 60 M + +S+ +GEG+R V+F +GC HRC GC NPK+WN G T+E EI+ E+A Sbjct: 1 MKVLNIIHDSVVDGEGLRTVVFFAGCPHRCFGCHNPKSWNICNGTEMTVE---EIVKEIA 57 Query: 61 ANPLLDGLTLAGGDPFFSAEEAAGFIQELRSVLPDYSVWIYTGYTYEELTAAPGSPEWNL 120 +NPL D +T +GGDPFF A E + ++ + + +W+YTGYT EE+ ++ + L Sbjct: 58 SNPLTD-VTFSGGDPFFQAAEVKQVARAVKDLKKN--LWMYTGYTLEEIQSSQNNDMIEL 114 Query: 121 LALCQVVIDGRFVEELKDTTLPYRGSSNQRIIDIQ 155 L V++DGRF E KD TLP+RGSSNQRII ++ Sbjct: 115 LHYGDVLVDGRFEIEKKDLTLPFRGSSNQRIIRLK 149 >ref|NP_810912.1| anaerobic ribonucleoside-triphosphate reductase activating protein [Bacteroides thetaiotaomicron VPI-5482] gb|AAO77106.1| anaerobic ribonucleoside-triphosphate reductase activating protein [Bacteroides thetaiotaomicron VPI-5482] Length = 164 Score = 140 bits (354), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 70/154 (45%), Positives = 100/154 (64%), Gaps = 3/154 (1%) Query: 1 MNICGYYPESINEGEGMRAVLFLSGCRHRCPGCFNPKTWNFNYGEPFTLERQREIIAEMA 60 +++ YPE+I +GEG+R ++L+GC H C GC NP++WN GE T ER + II E+ Sbjct: 11 LHLLSTYPETIVDGEGIRYSIYLAGCSHHCVGCHNPESWNPRAGELLTEERIQSIIREIK 70 Query: 61 ANPLLDGLTLAGGDPFFSAEEAAGFIQELRSVLPDYSVWIYTGYTYEELTAAPGSPEWNL 120 ANPLLDG+T +GGDPF++ E F++ ++ ++W YTGYTYEE+ A P + Sbjct: 71 ANPLLDGVTFSGGDPFYNPEAFLLFVKRVKEE-TGLNIWCYTGYTYEEILANPRLK--TV 127 Query: 121 LALCQVVIDGRFVEELKDTTLPYRGSSNQRIIDI 154 L V++DGRF + L L +RGSSNQRI+ I Sbjct: 128 LDYIDVLVDGRFEQALFSPYLEFRGSSNQRILRI 161 >ref|NP_357779.1| NrdD activating enzyme, generating glycyl radical [Streptococcus pneumoniae R6] pir||A97895 hypothetical protein nrdG [imported] - Streptococcus pneumoniae (strain R6) gb|AAK98989.1| NrdD activating enzyme, generating glycyl radical [Streptococcus pneumoniae R6] Length = 196 Score = 140 bits (354), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 69/165 (41%), Positives = 103/165 (62%), Gaps = 4/165 (2%) Query: 3 ICGYYPESINEGEGMRAVLFLSGCRHRCPGCFNPKTWNFNYGEPFTLERQREIIAEMAAN 62 I Y + +GEG+R L++SGC C GC+N TW+FN G P+T E + +I+A++ A Sbjct: 19 IIDYKAFNFVDGEGVRNSLYVSGCMFHCEGCYNVATWSFNAGIPYTAELEEQIMADL-AQ 77 Query: 63 PLLDGLTLAGGDPFFSAEEAAGFIQELRSVLPDYSVWIYTGYTYEELT-AAPGSPEWNLL 121 P + GLTL GG+PF + ++ +R LPD +W +TGYT+EE+ P E LL Sbjct: 78 PYVQGLTLLGGEPFLNTGILLPLVKRIRKELPDKDIWSWTGYTWEEMMLETPDKLE--LL 135 Query: 122 ALCQVVIDGRFVEELKDTTLPYRGSSNQRIIDIQASLAGTEIVHW 166 +L +++DGR+ ++ L +RGSSNQRIID+Q SL ++V W Sbjct: 136 SLIDILVDGRYDRTKRNLMLQFRGSSNQRIIDVQKSLKSGQVVIW 180 >ref|ZP_00046951.1| COG0602: Organic radical activating enzymes [Lactobacillus gasseri] Length = 237 Score = 140 bits (354), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 71/171 (41%), Positives = 104/171 (60%), Gaps = 5/171 (2%) Query: 2 NICGYYPESINEGEGMRAVLFLSGCRHRCPGCFNPKTWNFNYGEPFTLERQREIIAEMAA 61 I Y P + +GEG+R L++SGC CPGC+N NFNYG P+T E + +II +M+ Sbjct: 69 KIADYKPFNFVDGEGVRCSLYVSGCLFDCPGCYNLAAQNFNYGRPYTQELEDKIIEDMSQ 128 Query: 62 NPLLDGLTLAGGDPFFSAEEAAGFIQELRSVL-PDYSVWIYTGYTYEELTA-APGSPEWN 119 + + GLTL GG+PF + I +R +W ++GYT++EL P E Sbjct: 129 S-YVQGLTLLGGEPFLNTWVCLKLINRVRKEFGHTKDIWSWSGYTWDELQKETPDKKE-- 185 Query: 120 LLALCQVVIDGRFVEELKDTTLPYRGSSNQRIIDIQASLAGTEIVHWQPAV 170 +L+ +++DGRF+++LKD TL +RGSSNQRIID+Q SL ++V W V Sbjct: 186 MLSKIDILVDGRFMDDLKDLTLQFRGSSNQRIIDVQKSLKAKKVVIWDKLV 236 >gb|AAD00216.1| anaerobic ribonucleotide reductase activator protein [Lactococcus lactis subsp. cremoris] Length = 199 Score = 140 bits (353), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 68/165 (41%), Positives = 102/165 (61%), Gaps = 2/165 (1%) Query: 3 ICGYYPESINEGEGMRAVLFLSGCRHRCPGCFNPKTWNFNYGEPFTLERQREIIAEMAAN 62 I Y P + +GEG+R L++SGC C GC+N TW+F YG P+T E + +I+A++A Sbjct: 19 IADYKPFNFVDGEGVRCSLYVSGCMFHCEGCYNQATWSFRYGRPYTKELEDKIMADLAE- 77 Query: 63 PLLDGLTLAGGDPFFSAEEAAGFIQELRSVLPDYSVWIYTGYTYEELTAAPGSPEWNLLA 122 P + GLTL GG+PF + ++ +R LPD +W +TGYT+EE+ + +L Sbjct: 78 PYVQGLTLLGGEPFLNTTFLIPLLKRIRRELPDKDIWSWTGYTWEEMMLETDD-KLEMLD 136 Query: 123 LCQVVIDGRFVEELKDTTLPYRGSSNQRIIDIQASLAGTEIVHWQ 167 L V++DGRF K+ L +RGSSNQRIID+ S + ++V W+ Sbjct: 137 LLDVLVDGRFELSKKNLMLQFRGSSNQRIIDVPKSRSKGQVVIWE 181 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.139 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 285,427,458 Number of extensions: 11503717 Number of successful extensions: 24422 Number of sequences better than 1.0e-05: 82 Number of HSP's gapped: 24267 Number of HSP's successfully gapped: 82 Length of query: 171 Length of database: 757,237,578 Length adjustment: 117 Effective length of query: 54 Effective length of database: 439,570,995 Effective search space: 23736833730 Effective search space used: 23736833730 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 121 (51.2 bits)