BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0011.p (605 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00181952.1| hypothetical protein Exigu277301 [Exiguobacte... 174 7e-42 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 147 7e-34 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 139 2e-31 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 139 3e-31 ref|ZP_00036695.1| COG2972: Predicted signal transduction protei... 133 1e-29 >ref|ZP_00181952.1| hypothetical protein Exigu277301 [Exiguobacterium sp. 255-15] Length = 286 Score = 174 bits (440), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 9/282 (3%) Query: 328 SAVLISIGFTRPIKKLISFTQKVQIGQLDARMDVEREDEFGLLTRKITGMTRTINDLILN 387 +A L ++ T+PIK+L + +V+ G L A+ DE GLL R+ M + I+ LI Sbjct: 4 AASLAALKITKPIKQLTANVWRVEQGDLSAQFVATTNDEIGLLNRQFQRMIQRIDRLIKR 63 Query: 388 EYKLELANKTNQLKALQAQVNPHFLYNALQSIASLSLRYNAPKVYDLIYSLGSMMRYSMN 447 EY+L L N+TN+L+ALQ+Q+NPHFL+NALQSI + +L+ + Y I L MMRYSMN Sbjct: 64 EYRLALENRTNELRALQSQLNPHFLFNALQSIGTTTLQGDRKIAYRSITGLSQMMRYSMN 123 Query: 448 TERTQVPLRDEIEHVQNYVILQTERFGEENLRXXXXXXXXXXXXXXPKMILQPIVENIFK 507 E+T V L+ E++H+Q+Y+ LQ +RF + R PKMILQP EN FK Sbjct: 124 NEQTIVTLKQEVDHLQSYMRLQQQRFPDR-FRYIVDVPWHMNSIEIPKMILQPFAENYFK 182 Query: 508 HGF---ADGIQGGVISIRCALDGQGRLMLAVKDNGKGIAPERLEAILAGLAESGRTEREE 564 H F AD + ++ + DG +L++ V+++G + +LE+I + R E + Sbjct: 183 HAFNQQADATE-NYLAYKVRSDG-DQLIIQVENSGSVMEAAKLESIDQTMRMHRRPEDRQ 240 Query: 565 ---IGLYNVLARLRLQMSSGAQLLLSGNEDSGVTVTLLIPLD 603 IGL+N+ RL + A ++L + G + + IP++ Sbjct: 241 TSGIGLHNIYERLLIFYGEEASMILQSPAEGGFRIVIRIPVE 282 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 147 bits (371), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 145/545 (26%), Positives = 241/545 (44%), Gaps = 37/545 (6%) Query: 75 NVPSSFYTVLLTSKSKQ--DATPGSAVPDNRAVISTQLSNLFLSDRNTF--QIHLYVRAA 130 NV + Y + L S +Q D T PD IS FL + T +I + Sbjct: 68 NVQNMTYFISLHSNIQQFLDGTLEHLGPDEEYEISK-----FLQNFTTLYPEIAGILVVN 122 Query: 131 QQSNLLRGGYFRQEANSRYALGEHLDGTYRPYIEVTHIEHQYGIRSG---FPNLKPGIEP 187 QQ G Y E +R + + + YR +E I G G ++ + Sbjct: 123 QQ-----GDYLSNELYTRSSFNLNQESWYRQAVENKGIAKLIGKPQGRRITSHVHYREDE 177 Query: 188 VFTAHFPIYKTPSSDVLADLSIDYRLAELEGIVKSMYNSDTERLYVLNDQGQALFASDPD 247 V T I + + + + ID +L +E V+ + + L V++ +G +++ P Sbjct: 178 VVTVVRAIIDSTTGEEKGVILIDLKLRVIEEAVRDVRLGKSGYLMVVDQKGDPIYSPAPS 237 Query: 248 WI-GKPVKAGWSQLPGNSSSGHFTWKRDGFKGIVMYRHIEDPLFKG-SIIKLVPYEDLYE 305 + + +SQ + G FT + +G + +MY + F G ++I + + E Sbjct: 238 IMYEQSFDHRFSQ-----NYGIFTEEVEGERYQLMY---QQSAFTGWTLIGVFSTDQSVE 289 Query: 306 DARVITRFNTXXXXXXXXXXXXSAVLISIGFTRPIKKLISFTQKVQIGQLDARMDVERED 365 + + I + ++ +S +RPI +L+ QK + G L +R + E +D Sbjct: 290 EVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQKAESGDLTSRYEGEEQD 349 Query: 366 EFGLLTRKITGMTRTINDLILNEYKLELANKTNQLKALQAQVNPHFLYNALQSIASLSLR 425 E G L R M I LI + E + +L +LQA + PHFLYN L +I ++ + Sbjct: 350 EVGRLGRSFNTMIEQIGKLISLTERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARK 409 Query: 426 YNAPKVYDLIYSLGSMMRYSMNTERTQVPLRDEIEHVQNYVILQTERFGEENLRXXXXXX 485 NA V DL+ +L + R ++ T +PL DEIEH++NY+ +Q+ R+ + L Sbjct: 410 KNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQIQSVRY-KNKLNYSLVMP 468 Query: 486 XXXXXXXXPKMILQPIVENIFKHGFADGIQGGVISIRCALDGQGRLMLAVKDNGKGIAPE 545 K++LQPIVEN HG + G+I+I + L++ ++DNGKGI PE Sbjct: 469 SNMERLSILKIVLQPIVENAIYHGIKERRGPGLITIEAEREND-MLIIRIRDNGKGIKPE 527 Query: 546 RLEAILA--------GLAESGRTEREEIGLYNVLARLRLQMSSGAQLLLSGNEDSGVTVT 597 L+ + G E G+ + GL NV ARLRL + + + G VT Sbjct: 528 TLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRLTFGEPYGVKIDSVFNEGTVVT 587 Query: 598 LLIPL 602 + P+ Sbjct: 588 IFHPI 592 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 87/276 (31%), Positives = 140/276 (50%), Gaps = 4/276 (1%) Query: 329 AVLISIGFTRPIKKLISFTQKVQIGQLDARMDVEREDEFGLLTRKITGMTRTINDLILNE 388 +++IS +PI +L S ++ G D+ +++ DE +L + M I LI Sbjct: 299 SIVISGSIVKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKV 358 Query: 389 YKLELANKTNQLKALQAQVNPHFLYNALQSIASLSLRYNAPKVYDLIYSLGSMMRYSMNT 448 Y++E ++ +L+ LQ+Q+NPHFLYN L +I +L YNA +V D+I L + R S++ Sbjct: 359 YQVEKQKRSAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSD 418 Query: 449 ERTQVPLRDEIEHVQNYVILQTERFGEENLRXXXXXXXXXXXXXXPKMILQPIVENIFKH 508 + + + DE+ HV NY+ +Q R+ ++ + PK+I+QP+VEN H Sbjct: 419 GKEFITISDEVAHVSNYLEIQKIRY-KDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYH 477 Query: 509 GFADGIQGGVISIRCALDGQGRLMLAVKDNGKGIAPERLEAILAGLAESGRTEREEIGLY 568 G G+I++ + G L + V DNG G+ E+L + L ES E GLY Sbjct: 478 GLKLQKHKGIINVSIS-SKDGFLFIKVIDNGLGMDVEQLRTLRKNLWES--IETNHYGLY 534 Query: 569 NVLARLRLQMSSGAQLLLSGNEDSGVTVTLLIPLDS 604 N+ RL+L + + G V L IPL S Sbjct: 535 NINERLKLAFGKKYSIEIKSELKIGTQVLLRIPLIS 570 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 139 bits (349), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 84/279 (30%), Positives = 148/279 (53%), Gaps = 8/279 (2%) Query: 329 AVLISIGFTR----PIKKLISFTQKVQIGQLDARMDVE--REDEFGLLTRKITGMTRTIN 382 A L+S+ F+R P+++L + +KV+ G L+ +++ E +DE ++ ++ M IN Sbjct: 313 AFLVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERIN 372 Query: 383 DLILNEYKLELANKTNQLKALQAQVNPHFLYNALQSIASLSLRYNAPKVYDLIYSLGSMM 442 DLI KLE+ + +LKAL+AQ+NPHFLYN L +I + + ++ ++IYSL + Sbjct: 373 DLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLF 432 Query: 443 RYSMNTERTQVPLRDEIEHVQNYVILQTERFGEENLRXXXXXXXXXXXXXXPKMILQPIV 502 R ++N + +R E E ++ Y+ LQ++R+ + + PK+ILQP V Sbjct: 433 RLTLNRGEEFIQVRGEKELIERYLFLQSKRY-KNKFKYSVKISDEILDYYIPKLILQPFV 491 Query: 503 ENIFKHGFADGIQGGVISIRCALDGQGRLMLAVKDNGKGIAPERLEAILAGLAESGRTER 562 EN HG + + + + +G+ L +KDNG G++ E LE + + E+ Sbjct: 492 ENAIVHGLENNSEESFVEVIGEKEGEN-LKFIIKDNGPGMSEETLEKLKRFIESENIEEK 550 Query: 563 EEIGLYNVLARLRLQMSSGAQLLLSGNEDSGVTVTLLIP 601 + NV RLRL +L + + G T++L++P Sbjct: 551 VGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|ZP_00036695.1| COG2972: Predicted signal transduction protein with a C-terminal ATPase domain [Enterococcus faecium] Length = 574 Score = 133 bits (334), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 133/247 (53%), Gaps = 4/247 (1%) Query: 353 GQLDARMDVER-EDEFGLLTRKITGMTRTINDLILNEYKLELANKTNQLKALQAQVNPHF 411 G L+ R+D+ E E L+ I M +IN + + YKLE+ + ++ALQAQ+NPHF Sbjct: 326 GNLETRIDITNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHF 385 Query: 412 LYNALQSIASLSLRYNAPKVYDLIYSLGSMMRYSMNTERTQVPLRDEIEHVQNYVILQTE 471 LYN L+ I ++ + ++ D++Y+ +++R + N E+T + L++E++ + YV L Sbjct: 386 LYNTLEYIRMYAISEGSEELADVVYAFSALLRNNTNQEKT-ITLKEELDFCEKYVYLYQM 444 Query: 472 RFGEENLRXXXXXXXXXXXXXXPKMILQPIVENIFKHGFADGIQGGVISIRCALDGQGRL 531 R+ + PK ++QP+VEN FKHG +S++ +G+ R+ Sbjct: 445 RYPNR-VAYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGK-RV 502 Query: 532 MLAVKDNGKGIAPERLEAILAGLAESGRTEREEIGLYNVLARLRLQMSSGAQLLLSGNED 591 + +KDNGKG+ +RL+ I L+ IGL NV RLR S + L NE Sbjct: 503 RIIIKDNGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNET 562 Query: 592 SGVTVTL 598 G+TV++ Sbjct: 563 GGLTVSI 569 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 810,847,926 Number of extensions: 32701363 Number of successful extensions: 78957 Number of sequences better than 1.0e-05: 177 Number of HSP's gapped: 78651 Number of HSP's successfully gapped: 177 Length of query: 605 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 473 Effective length of database: 398,844,510 Effective search space: 188653453230 Effective search space used: 188653453230 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)