BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0032.p (220 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_391372.1| ATP phosphoribosyltransferase [Bacillus subtili... 280 2e-74 ref|NP_244450.1| ATP phosphoribosyltransferase [Bacillus halodur... 271 8e-72 ref|NP_623700.1| ATP phosphoribosyltransferase (histidine biosyn... 212 5e-54 ref|ZP_00060492.1| COG0040: ATP phosphoribosyltransferase [Clost... 201 9e-51 ref|ZP_00180443.1| hypothetical protein Mther162001 [Moorella th... 200 2e-50 >ref|NP_391372.1| ATP phosphoribosyltransferase [Bacillus subtilis] sp|O34520|HIS1_BACSU ATP phosphoribosyltransferase pir||C69641 ATP phosphoribosyltransferase (EC 2.4.2.17) [similarity] - Bacillus subtilis gb|AAC67294.1| ATP phosphoribosyltransferase [Bacillus subtilis] emb|CAB15497.1| ATP phosphoribosyltransferase [Bacillus subtilis subsp. subtilis str. 168] Length = 213 Score = 280 bits (715), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 134/210 (63%), Positives = 170/210 (80%), Gaps = 3/210 (1%) Query: 3 MSQILKVAMPKGRIYNKAAELFRQAGLPIPPDGEESRKLVISLPEAGMEFILAKPVDVPT 62 M ++L +AMPKGRI+ +AA L RQAG +P + E+SRKL+I +PE + FILAKP+DV T Sbjct: 1 MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVPEENLRFILAKPMDVTT 60 Query: 63 YVEYGVADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIGLPN--WQPGIQQRVATKYP 120 YVE+GVAD+GI GKDV+LEE RDVYE+LDL I++C +++ GLPN W G+ R+ATKYP Sbjct: 61 YVEHGVADVGIAGKDVMLEEERDVYEVLDLNISKCHLAVAGLPNTDWS-GVAPRIATKYP 119 Query: 121 NVASRYFREQGQQVEVVKLNGSIELAPLIGLADRIVDMVETGQTLKDNGLVEMKSIFEIT 180 NVAS YFREQG+QVE++KLNGSIELAPLIGLADRIVD+V TGQTLK+NGLVE + I +IT Sbjct: 120 NVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGQTLKENGLVETEHICDIT 179 Query: 181 SRLVANRVSYRMKNEEIQQLCDRLQAVITG 210 SR + N VSYRMK++ I ++ RL V+ G Sbjct: 180 SRFIVNPVSYRMKDDVIDEMASRLSLVVEG 209 >ref|NP_244450.1| ATP phosphoribosyltransferase [Bacillus halodurans] sp|Q9K6Z1|HIS1_BACHD ATP phosphoribosyltransferase pir||G84097 ATP phosphoribosyltransferase hisG [imported] - Bacillus halodurans (strain C-125) dbj|BAB07302.1| ATP phosphoribosyltransferase [Bacillus halodurans] Length = 212 Score = 271 bits (693), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 126/210 (60%), Positives = 171/210 (81%), Gaps = 2/210 (0%) Query: 5 QILKVAMPKGRIYNKAAELFRQAGLPIPPDGEESRKLVISLPEAGMEFILAKPVDVPTYV 64 +L VAMPKGRI+++A L R+AG +P + E SRKL++ +PE M FILAKP+DVPTYV Sbjct: 2 SMLTVAMPKGRIFDEAVGLLRKAGYNLPAEFEASRKLIVDVPEENMRFILAKPMDVPTYV 61 Query: 65 EYGVADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIGLPNWQP--GIQQRVATKYPNV 122 E+GVAD+G+ GKDV+LEE RDVYE+LDL I+ C +++ GLPN++ + +VA+KYP++ Sbjct: 62 EHGVADVGVAGKDVMLEEERDVYEVLDLKISECYLAVAGLPNYEKKHDLNPKVASKYPHL 121 Query: 123 ASRYFREQGQQVEVVKLNGSIELAPLIGLADRIVDMVETGQTLKDNGLVEMKSIFEITSR 182 A+RYF+EQG+QVE++KLNGSIELAPLIGLADRIVD+V TG+TL++NGLVE++ + ITSR Sbjct: 122 ATRYFKEQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGRTLRENGLVELEKMMTITSR 181 Query: 183 LVANRVSYRMKNEEIQQLCDRLQAVITGPG 212 L+ N VSYRMK+E I ++ +RL V+ G G Sbjct: 182 LIVNPVSYRMKDERIDEMVERLLQVVEGDG 211 >ref|NP_623700.1| ATP phosphoribosyltransferase (histidine biosynthesis) [Thermoanaerobacter tengcongensis] sp|Q8R881|HIS1_THETN ATP phosphoribosyltransferase gb|AAM25304.1| ATP phosphoribosyltransferase (histidine biosynthesis) [Thermoanaerobacter tengcongensis] Length = 210 Score = 212 bits (539), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 99/208 (47%), Positives = 153/208 (73%), Gaps = 2/208 (0%) Query: 5 QILKVAMPKGRIYNKAAELFRQAGLPIPPDGEESRKLVISLPEAGMEFILAKPVDVPTYV 64 I+ +A+PKGR+ A LF++AG+ + SRKL++ + ++F+L KP+DVPTYV Sbjct: 2 DIVSIALPKGRMTEDAVVLFKKAGISNDVLKDISRKLILEDNKNAIKFMLVKPMDVPTYV 61 Query: 65 EYGVADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIGLPNWQPGI--QQRVATKYPNV 122 E+G AD+G+ GKD+LLE+ +D+YE+LDL CRM + G PN + +RVATK+PNV Sbjct: 62 EHGAADLGVCGKDILLEQKKDLYEVLDLKFGFCRMVVAGPPNVKDSFLTNKRVATKFPNV 121 Query: 123 ASRYFREQGQQVEVVKLNGSIELAPLIGLADRIVDMVETGQTLKDNGLVEMKSIFEITSR 182 A +F+++G+ VE++KLNGS+ELAP++GL++ IVD+VETG+TL++NGLV ++ IF T+R Sbjct: 122 AEEFFKKKGENVEIIKLNGSVELAPIVGLSEVIVDIVETGRTLRENGLVVIEEIFPSTAR 181 Query: 183 LVANRVSYRMKNEEIQQLCDRLQAVITG 210 L+ N+ S + K+E I+ + +L+ VI G Sbjct: 182 LIVNKASMKTKSERIKDIILKLREVING 209 >ref|ZP_00060492.1| COG0040: ATP phosphoribosyltransferase [Clostridium thermocellum ATCC 27405] Length = 213 Score = 201 bits (511), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 100/204 (49%), Positives = 144/204 (70%), Gaps = 5/204 (2%) Query: 7 LKVAMPKGRIYNKAAELFRQAGLPIPPDGEESRKLVISLPEAGMEFILAKPVDVPTYVEY 66 L +A+ KGR+ + + ELF G+ SRKL+++ + ++F LAKP DVPTYVEY Sbjct: 4 LTIALSKGRLTDMSVELFEAIGIDCTELKNSSRKLILTDEKNKIKFFLAKPSDVPTYVEY 63 Query: 67 GVADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIG----LPNWQPGIQQRVATKYPNV 122 G ADIGIVGKD L+EE R +YE+L+LG A C+M + G + +RVATKYP + Sbjct: 64 GAADIGIVGKDTLMEEGRHLYEVLNLGFAACKMVVAGPAELMGKLDRLTNKRVATKYPRI 123 Query: 123 ASRYF-REQGQQVEVVKLNGSIELAPLIGLADRIVDMVETGQTLKDNGLVEMKSIFEITS 181 A YF ++ + +EV+KLNGS+ELAPL+GL++ IVD+VE+G+TLK+NGLV + +I +I++ Sbjct: 124 AREYFEHKRKESIEVIKLNGSVELAPLVGLSEVIVDLVESGRTLKENGLVVLDTIADISA 183 Query: 182 RLVANRVSYRMKNEEIQQLCDRLQ 205 RLV NRVS +MK+E I + D ++ Sbjct: 184 RLVVNRVSMKMKSERINPIIDAIR 207 >ref|ZP_00180443.1| hypothetical protein Mther162001 [Moorella thermoacetica ATCC 39073] Length = 228 Score = 200 bits (508), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 99/215 (46%), Positives = 143/215 (66%), Gaps = 12/215 (5%) Query: 2 IMSQILKVAMPKGRIYNKAAELFRQAGLPIPPDGEESRKLVISLPEAGMEFILAKPVDVP 61 +++ +L +A+PKG++ A +L + AGLP+ E+R+L + P G+ +++ +P DVP Sbjct: 1 MVTNLLTLALPKGKLGQDALQLLQAAGLPVEGVATEARQLTFTFPAPGIRYLICRPTDVP 60 Query: 62 TYVEYGVADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIG-----------LPNWQPG 110 TYVEYG AD+GIVGKD L E DV+EL+DLG CR + L N G Sbjct: 61 TYVEYGAADLGIVGKDTLAEAGADVFELVDLGFGYCRFVVAAPRERWEEAGRSLENLLAG 120 Query: 111 IQQRVATKYPNVASRYFREQGQQVEVVKLNGSIELAPLIGLADRIVDMVETGQTLKDNGL 170 +RVATK+P VA+ +F+E+G VE++KL+G+IELAP GLAD IVD+V TG+TLK+N L Sbjct: 121 -SRRVATKFPRVAASFFQERGLPVEIIKLHGNIELAPRAGLADLIVDIVSTGRTLKENDL 179 Query: 171 VEMKSIFEITSRLVANRVSYRMKNEEIQQLCDRLQ 205 VE+ IF T+RL+ANRVSYR+ + + + L+ Sbjct: 180 VEVAPIFSSTARLIANRVSYRINYRRLTSVVEALK 214 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.139 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 312,344,967 Number of extensions: 12451633 Number of successful extensions: 33193 Number of sequences better than 1.0e-05: 356 Number of HSP's gapped: 32845 Number of HSP's successfully gapped: 356 Length of query: 220 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 99 Effective length of database: 428,710,599 Effective search space: 42442349301 Effective search space used: 42442349301 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 123 (52.0 bits)