BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0003.p (757 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00100244.1| COG0551: Zn-finger domain associated with top... 733 0.0 ref|NP_349549.1| Topoisomerase B [Clostridium acetobutylicum] >g... 678 0.0 ref|NP_781100.1| DNA topoisomerase I [Clostridium tetani E88] >g... 677 0.0 ref|NP_562424.1| DNA topoisomerase III [Clostridium perfringens]... 658 0.0 ref|NP_976812.1| DNA topoisomerase III [Bacillus cereus ATCC 109... 648 0.0 >ref|ZP_00100244.1| COG0551: Zn-finger domain associated with topoisomerase type I [Desulfitobacterium hafniense] Length = 729 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/728 (51%), Positives = 491/728 (67%), Gaps = 36/728 (4%) Query: 47 KVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANWA 106 K LVL EKPSV R+IA+++GC K G +Y+VTWALGHLV LA+PE Y K+ W Sbjct: 3 KSLVLTEKPSVGRDIAKLLGCNQKGNGCFIGSRYIVTWALGHLVTLADPEAYGEKYKQWR 62 Query: 107 LEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMAG 166 LEDLP+LP+ +L V++ETS+QY AV+QL+++ D+EELI+ATDA REGEL+ARWI+ AG Sbjct: 63 LEDLPMLPKDMELVVIKETSKQYAAVKQLLRQPDVEELIIATDAGREGELVARWIIGKAG 122 Query: 167 WKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCKF 226 WKKP +RLWISSQTDKAIREGF +L+PG+ ++ LY +A CRA+ADW +GLNVTRALTCK+ Sbjct: 123 WKKPIKRLWISSQTDKAIREGFNNLKPGKAYESLYAAAECRAQADWYVGLNVTRALTCKY 182 Query: 227 GAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQG-GDGRIFERD 285 A LSAGRVQTPTL ++++RE EI F + Y + A F W+ +G G R+F++ Sbjct: 183 NAQLSAGRVQTPTLALVVEREKEIQNFVPKGYWTINARVQGFSLSWQDKGNGQNRMFDQR 242 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 +L +KL G G++A+++K K E P AYDLTELQRDANRK+GFSAKQTSS++Q+LY Sbjct: 243 KAEQLVQKLRGHKGQVAEIKKEAKREQPPQAYDLTELQRDANRKYGFSAKQTSSIMQQLY 302 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHKLVTYPRTDSRYL+ D+ TL ERL ++AVG TKR+VD+SKV Sbjct: 303 EQHKLVTYPRTDSRYLSEDIVPTLPERLKTIAVGPYSELARRVLRTKITPTKRLVDNSKV 362 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 +DHHAIIPTEQTV LN+LS EE K+YDLIVRRFI++ PA Y+ V V + GE+F K Sbjct: 363 TDHHAIIPTEQTVFLNKLSPEEAKIYDLIVRRFIAVLSPAFEYEQTTVKVEIQGELFTAK 422 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 G VK GWR VY G ++D+E ++ E LP+L+ + + V + PG+T+P Sbjct: 423 GKIVKQKGWRSVYEGREAADEEADHEEQEQ-----NLPDLQPKQTLEVLDLKLLPGKTKP 477 Query: 526 PKRYNEASLLTQMEK-----------------HGLGTPATRADIIEKLVSSDTIERQGNL 568 PKRY EA+LL+ ME GLGTPATRADIIEKL SS +ER G Sbjct: 478 PKRYTEATLLSAMEHPGQRVNDEALRETLEKTSGLGTPATRADIIEKLFSSFYMERNGKE 537 Query: 569 LHPTGKGKQLIGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVK 628 + PT KG QLIGLV +L++PELTA+WE +L +I++G+ + F+QGI+S A +LVS V Sbjct: 538 IVPTSKGIQLIGLVPSELKSPELTAKWEQQLSEISKGREDRQRFIQGIKSYATQLVSEVS 597 Query: 629 NSGAEYKPHNVSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCH 688 SG Y+ N++ + CP CG LL+ K KRG++LVC +CGY R G SN RCPQCH Sbjct: 598 GSGRTYRHDNMTRAKCPECGKFLLQVKGKRGEMLVCQDRECGY-RQGLSVQSNARCPQCH 656 Query: 689 KKMELK-EGKAGLYVQCLGCGITETMDKDHKH---------INKREQQRLVQQYSKQESV 738 KKM+L+ EG+ ++ CG E + +K NKRE +Q+ K + Sbjct: 657 KKMKLQGEGEHKIFT--CACGYREKLSAFNKRREQEGSKGSYNKREVNHYLQKQEKDAPL 714 Query: 739 GSNLGELL 746 + L + L Sbjct: 715 NTALADAL 722 >ref|NP_349549.1| Topoisomerase B [Clostridium acetobutylicum] pir||F97262 topoisomerase B [imported] - Clostridium acetobutylicum gb|AAK80889.1| Topoisomerase B [Clostridium acetobutylicum] Length = 728 Score = 678 bits (1750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/711 (46%), Positives = 465/711 (65%), Gaps = 31/711 (4%) Query: 47 KVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANWA 106 K+LVLAEKPSVAR++A+V+ +K+++EG KYVV WALGHLV LA+PE Y K+ W+ Sbjct: 3 KILVLAEKPSVARDLAKVLKANINKKTHLEGNKYVVIWALGHLVSLADPESYGEKYKKWS 62 Query: 107 LEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMAG 166 ++ LP+LP+ KL VL+ TS+ + ++++M+R+D++EL++ATDA REGEL+ARWI+ MA Sbjct: 63 MDTLPMLPKNMKLSVLKNTSKHFYDIKKVMERKDLDELVIATDAGREGELVARWIIEMAK 122 Query: 167 WKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCKF 226 WKKP +RLWISSQTD+A+R+GFA LR GR+++ LY+SA+CR+EADW +GLNVTRALTCK+ Sbjct: 123 WKKPIKRLWISSQTDRAVRDGFAHLRDGRDYENLYKSAKCRSEADWFVGLNVTRALTCKY 182 Query: 227 GAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERDT 286 A LSAGRVQTPTL MI+ RE EI F+ ++Y + SF W + GD +IF ++ Sbjct: 183 NAQLSAGRVQTPTLYMIVSREEEIRKFKPKDYYTIEGKVKSFSMNWHDKSGDFKIFNKER 242 Query: 287 TAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLYE 346 K++ + G G+I V +S+K + P YDLTELQRDANR FGFSAK+T S++QRLYE Sbjct: 243 AEKIEALVKGSKGKIVDVSESKKKKYSPALYDLTELQRDANRFFGFSAKETLSIMQRLYE 302 Query: 347 QHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKVS 406 HKL+TYPRTDSRY+ D+ TL +RL ++++G + K VDDSKV+ Sbjct: 303 NHKLLTYPRTDSRYIPHDVVATLPDRLRAISIGKYSKFAAEILRSKINVHKGFVDDSKVT 362 Query: 407 DHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVKG 466 DH+AIIPTE+ L LS EE K+YDL+V+RF+S+ P Y V V GE+F KG Sbjct: 363 DHYAIIPTEERPALGALSNEEFKIYDLVVKRFLSIMLPPFEYIQTTVKAEVAGEIFIAKG 422 Query: 467 TTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQPP 526 VK GW+EVY D+ E+ ++ LPE+ +GE +T I+ G+T+PP Sbjct: 423 KVVKSKGWKEVY-------DKTEDFEEKSELKDQMLPEMNKGEDITFSTVSIKKGQTKPP 475 Query: 527 KRYNEASLLTQMEKH------------------GLGTPATRADIIEKLVSSDTIERQGNL 568 R+ EA+LL+ ME GLGT ATRADIIEKL + IE++GN Sbjct: 476 SRFTEATLLSAMENPQRYVSMDKISAKTLGETGGLGTVATRADIIEKLYKTFYIEKKGNE 535 Query: 569 LHPTGKGKQLIGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGVK 628 + PT KGKQL+ LV L++P LTA+WE +L+ I++G+ F+ I+ A +LV VK Sbjct: 536 IVPTSKGKQLVNLVPSDLKSPLLTAKWEGQLDAISKGKLNGVSFVNEIKGYASKLVDDVK 595 Query: 629 NSGAEYKPHNVSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQCH 688 S +K N++ + CP CG +L+ K+G++LVC +CG+ R +N RCP+CH Sbjct: 596 GSKDTFKYDNLTGTKCPECGKYMLQVNGKKGRMLVCQDRECGH-RENLAMFTNVRCPECH 654 Query: 689 KKMELK-EGKAGLYVQCLGCGITE---TMDKDHKHINKREQQRLVQQYSKQ 735 KK+EL+ EG+ +YV C C E + K K N + +R V Y K+ Sbjct: 655 KKLELRGEGEGRIYV-CPNCSFREKYSSFQKRFKGNNNKVNKREVSNYMKK 704 >ref|NP_781100.1| DNA topoisomerase I [Clostridium tetani E88] gb|AAO35037.1| DNA topoisomerase I [Clostridium tetani E88] Length = 730 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/729 (46%), Positives = 474/729 (65%), Gaps = 36/729 (4%) Query: 47 KVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANWA 106 K LVLAEKPSV REIARV+ C +SYIE KYVVTWALGHLV LA+PE Y+NK+ W Sbjct: 3 KTLVLAEKPSVGREIARVLKCNKNSRSYIESNKYVVTWALGHLVTLADPEVYDNKYKKWE 62 Query: 107 LEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMAG 166 +E LP+LP+ KL V+ +TS+Q+ V++LM R DI+E+++ATDA REGEL+ARWI+ A Sbjct: 63 METLPMLPKYMKLCVIGKTSKQFNEVKKLMNRNDIDEIVIATDAGREGELVARWIIEKAR 122 Query: 167 WKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCKF 226 KP +RLWISSQTDKAI +GF +L+PG++++ LY+SA CR+EADW++GLNVTRALTCK+ Sbjct: 123 VNKPIKRLWISSQTDKAIIDGFNNLKPGKDYENLYKSAVCRSEADWLVGLNVTRALTCKY 182 Query: 227 GAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERDT 286 A LSAGRVQTPTL +I++RE EI F+ ++Y + A Q W+ + G F D Sbjct: 183 NAQLSAGRVQTPTLALIVEREEEIKNFKPRDYYNIVAKTKGIQFNWQDKKGQMATFNEDF 242 Query: 287 TAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLYE 346 + K++G G + +V + +K + P YDLTELQRDANR FG+SAK+T S++QRLYE Sbjct: 243 ANNILAKVSGEIGNVTEVIEKDKKQYAPALYDLTELQRDANRIFGYSAKETLSIMQRLYE 302 Query: 347 QHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKVS 406 HK++TYPRTDSRY++ D+ T+ +RL S+++G K VDDSKVS Sbjct: 303 NHKVLTYPRTDSRYISKDIVATIPQRLKSISIGIYSKFAEEILRGKIVAHKGFVDDSKVS 362 Query: 407 DHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVKG 466 DHHAIIPTE+ V L+ LS +ERK+YDL+++RF+S+ P Y + V V+GEVF KG Sbjct: 363 DHHAIIPTEERVKLSNLSGDERKIYDLVIKRFLSVMLPPFEYIQTTIKVEVNGEVFIAKG 422 Query: 467 TTVKDGGWREVYGG-DMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 +K GW+ VY D++ D+ D + E LP++ +G+A+ I G+T+P Sbjct: 423 KNIKHNGWKAVYNKEDLNEDNNDGDGLKEQV-----LPQIIKGDAIKFNLVNINKGQTKP 477 Query: 526 PKRYNEASLLTQMEKH------------------GLGTPATRADIIEKLVSSDTIERQGN 567 P R+NE +LL+ ME GLGT ATRADIIEKL +S IE++G Sbjct: 478 PARFNEGTLLSAMENPQKYIKLNKEYAKTLGETGGLGTVATRADIIEKLYNSFYIEKKGK 537 Query: 568 LLHPTGKGKQLIGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSGV 627 + PT KGKQ+I LV L++P LTA WE +LE I++G+ + F+ +R+ + +LV V Sbjct: 538 EIIPTSKGKQIIDLVPQDLKSPILTAEWEKKLELISKGKISGKEFINNMRNYSTKLVQDV 597 Query: 628 KNSGAEYKPHNVSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQC 687 KNS +Y +N++ + CPNC +LE KRGK+LVC +CGY R + +N RCP+C Sbjct: 598 KNSNEKYIHNNLTGTKCPNCEKYMLEVNGKRGKILVCQDRECGY-RENISRFTNVRCPEC 656 Query: 688 HKKMELK-EGKAGLYVQCLGCGITETMDKDHKHI-------NKREQQRLVQQYSKQ--ES 737 HKK+EL+ EG+ +YV C C E + +K +KRE R +++ +Q E Sbjct: 657 HKKLELRGEGEGQIYV-CSKCTFREKLSSFNKRFKEKGNNADKREVSRYMKKMKEQDKEP 715 Query: 738 VGSNLGELL 746 + S L + L Sbjct: 716 MNSALADAL 724 >ref|NP_562424.1| DNA topoisomerase III [Clostridium perfringens] dbj|BAB81214.1| DNA topoisomerase III [Clostridium perfringens str. 13] Length = 728 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/732 (46%), Positives = 471/732 (64%), Gaps = 41/732 (5%) Query: 46 MKVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANW 105 MK LVLAEKPSV REIA+V+ C N + SYIEG YV+TWALGHLV L PEDY+NK W Sbjct: 1 MKKLVLAEKPSVGREIAKVLKCNNNKGSYIEGKDYVITWALGHLVELQSPEDYDNKLKTW 60 Query: 106 ALEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMA 165 ++E LP+LP+ KLKV+++ ++Q+ V++ M+R+DI+E+I+ATDA REGEL+ARWI+ A Sbjct: 61 SMETLPMLPKHMKLKVIKKATKQFYEVKKQMERKDIDEIIIATDAGREGELVARWIIEKA 120 Query: 166 GWKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCK 225 KKP +RLWISSQTDKAI +GF +L+PG ++ LY++A+CRAEADW++GLNVTRALTCK Sbjct: 121 HVKKPIKRLWISSQTDKAILDGFKNLKPGENYNNLYKAAQCRAEADWLVGLNVTRALTCK 180 Query: 226 FGAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTADFGSFQAGWRAQGGDGRIFERD 285 + A LSAGRVQ+PTL MI+ RE +I F+ +EY + + W + + RIF+ D Sbjct: 181 YNAQLSAGRVQSPTLAMIVQREEDIKNFKPKEYSTILIETDKCNFTWINKDNNSRIFKND 240 Query: 286 TTAKLKEKLT-GRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRL 344 K+ L +SG+I + +S K + P YDLTELQRD N+ FG+SAKQT +++QRL Sbjct: 241 FKEKVVSNLNEKKSGKIININESNKKKFSPQLYDLTELQRDCNKIFGYSAKQTLNIMQRL 300 Query: 345 YEQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSK 404 YE HKL+TYPRTDSRY++ D+ T+ +RL +VA G K VDD+K Sbjct: 301 YENHKLLTYPRTDSRYISKDIVSTIPDRLKAVATGEFRTIANDLLKNPIKANKSFVDDNK 360 Query: 405 VSDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHV 464 VSDHHAIIPTE+ L LS++ER++Y+L+V+RF+S+ P Y +T V+GE Sbjct: 361 VSDHHAIIPTEEKGNLANLSSDERRVYELVVKRFLSVLMPPFEYIQTTLTGEVNGEKLIA 420 Query: 465 KGTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQ 524 KG VK GW+++Y D DDE E E +LP+L+EG+ V + ++ G T+ Sbjct: 421 KGKVVKAKGWKKLY--DREVDDEGEEDIKEQ-----ELPKLKEGDEFKVLKVNVKKGETK 473 Query: 525 PPKRYNEASLLTQMEKH------------------GLGTPATRADIIEKLVSSDTIERQG 566 PP R+NE +LL+ ME GLGT ATRADIIEKL +S IE++G Sbjct: 474 PPARFNEGTLLSAMENPQKFISVDKSSAKTLGETGGLGTVATRADIIEKLFNSFVIEKRG 533 Query: 567 NLLHPTGKGKQLIGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSG 626 + PT KGKQLI LV L++P LTA WE LE+I++G+G + F++ IR+ LV Sbjct: 534 KEIIPTSKGKQLIDLVPKDLKSPLLTANWEEMLERISKGKGDSKKFIKDIRNYTVALVED 593 Query: 627 VKNSGAEYKPHNVSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQ 686 VK +++ N++ CP CG +LE K K G + VC +CGY R +++N RCP+ Sbjct: 594 VKLGESKFHHDNLTGKKCPQCGKYMLEVKGKNGTMNVCQDRECGY-RENISRITNARCPE 652 Query: 687 CHKKMELK-EGKAGLYVQCLG--CGITET-------MDKDHKHINKREQQRLVQQYSKQ- 735 C KK+EL+ G+ +YV C G C E +K++K NKRE +++Q+ K+ Sbjct: 653 CKKKLELRGHGEGKIYV-CPGVNCNFREKESQFKKRFEKNNK-TNKREVNKIMQKMKKEA 710 Query: 736 -ESVGSNLGELL 746 E V + +LL Sbjct: 711 NEDVNNPFADLL 722 >ref|NP_976812.1| DNA topoisomerase III [Bacillus cereus ATCC 10987] gb|AAS39420.1| DNA topoisomerase III [Bacillus cereus ATCC 10987] Length = 729 Score = 648 bits (1672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/714 (45%), Positives = 459/714 (64%), Gaps = 32/714 (4%) Query: 47 KVLVLAEKPSVAREIARVMGCGNKQKSYIEGPKYVVTWALGHLVGLAEPEDYNNKFANWA 106 K +V+AEKPSVAR+IARV+ C K Y+EG KY+VTWALGHLV LA+PE Y+ K+ W Sbjct: 3 KSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWN 62 Query: 107 LEDLPILPEKAKLKVLRETSQQYKAVQQLMKRQDIEELIVATDAAREGELLARWIMNMAG 166 LEDLP+LPE+ KL V+++T +Q+ AV+ + R+D+ E+IVATDA REGEL+ARWI++ Sbjct: 63 LEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVR 122 Query: 167 WKKPFRRLWISSQTDKAIREGFASLRPGREFDRLYESARCRAEADWMIGLNVTRALTCKF 226 KP +RLWISS TDKAI++GFA+L+PGR +D LY SA R+EADW IGLN TRALT +F Sbjct: 123 INKPIKRLWISSVTDKAIKDGFANLKPGRAYDNLYASAVARSEADWYIGLNATRALTTRF 182 Query: 227 GAPLSAGRVQTPTLGMIMDRENEITGFRSQEYDLLTAD-FGSFQAGWRAQGGDGRIFERD 285 A L+ GRVQTPT+ MI +RE+EI F++Q Y + A + W+ G+ R F ++ Sbjct: 183 NAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKE 242 Query: 286 TTAKLKEKLTGRSGRIAKVQKSEKSEPHPLAYDLTELQRDANRKFGFSAKQTSSVLQRLY 345 + + L + + ++ K +K P YDLTELQRDAN+KFG+SAK+T +++Q+LY Sbjct: 243 KIDGIVKGLDKHNATVMEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLY 302 Query: 346 EQHKLVTYPRTDSRYLTSDMTGTLKERLDSVAVGXXXXXXXXXXXXXXXITKRVVDDSKV 405 EQHK++TYPRTDSRY++SD+ GTL ERL + VG K VDDSKV Sbjct: 303 EQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKV 362 Query: 406 SDHHAIIPTEQTVLLNQLSAEERKLYDLIVRRFISLFYPAARYDAVAVTVNVDGEVFHVK 465 SDHHAIIPTE V + + +ERK+YDL+V+RF+++ +PA Y+ + + V E F + Sbjct: 363 SDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIAR 422 Query: 466 GTTVKDGGWREVYGGDMSSDDEDENTADEPAAGSVKLPELREGEAVTVQRCIIRPGRTQP 525 G T+ GW+EVY DD ++ ++ LP + +G+ +TV+ + G+T+ Sbjct: 423 GKTILHAGWKEVYENRFEDDDVTDDVKEQL------LPRIEKGDTLTVKLIMQTSGQTKA 476 Query: 526 PKRYNEASLLTQMEKH-------------------GLGTPATRADIIEKLVSSDTIERQG 566 P R+NEA+LL+ ME GLGT ATRADII+KL +S IE++G Sbjct: 477 PARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRG 536 Query: 567 NLLHPTGKGKQLIGLVAGQLRTPELTARWEAELEKIARGQGRPEPFLQGIRSMAQELVSG 626 +H T KG+QL+ LV +L++P LT WE +LE IA+G+ + E F+ +++ +E+VS Sbjct: 537 KDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSE 596 Query: 627 VKNSGAEYKPHNVSNSHCPNCGTRLLEKKTKRGKLLVCPADDCGYTRAGEKQLSNRRCPQ 686 +K+S +YK N+S CP+CG +LE K+GK+LVC +CG+ R + +N RCPQ Sbjct: 597 IKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGH-RKNVSRTTNARCPQ 655 Query: 687 CHKKMELKEGKAGLYVQCLGCGITETMDKDH----KHINKREQQRLVQQYSKQE 736 C KK+EL+ AG C CG E + K K + +R VQ+Y KQ+ Sbjct: 656 CKKKLELRGEGAGQIFAC-KCGYREKLSKFQERRKKESGNKADKRDVQKYMKQQ 708 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.133 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,082,468,419 Number of extensions: 45052781 Number of successful extensions: 117843 Number of sequences better than 1.0e-05: 1027 Number of HSP's gapped: 114932 Number of HSP's successfully gapped: 1115 Length of query: 757 Length of database: 757,237,578 Length adjustment: 133 Effective length of query: 624 Effective length of database: 396,129,411 Effective search space: 247184752464 Effective search space used: 247184752464 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 130 (54.7 bits)