BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0599.0152.p
         (69 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

FN0585 [TK] COG0745 Response regulators consisting of a CheY-lik...    70   1e-12
SPy2027 [TK] COG0745 Response regulators consisting of a CheY-li...    61   4e-10
all1964 [TK] COG0745 Response regulators consisting of a CheY-li...    60   8e-10
L0131 [TK] COG0745 Response regulators consisting of a CheY-like...    60   8e-10
ML0131 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr...    60   8e-10

>FN0585 [TK] COG0745 Response regulators consisting of a CheY-like
          receiver domain and a winged-helix DNA-binding domain
          Length = 224

 Score = 69.7 bits (169), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 31/64 (48%), Positives = 46/64 (71%)

Query: 1  VEDEVHLTEALTQILKKQNYSVDAVHDGRSGLDYAQSGIYDLLLLDIMMPEMDGFTVLKK 60
          VEDE  L   +++ LKK N+SVD+V DG   L+Y   G YD+++LD+MMP+M+G+ V+K 
Sbjct: 6  VEDEKDLNNIISKHLKKNNFSVDSVFDGEEALEYLSYGDYDVIILDVMMPKMNGYEVVKN 65

Query: 61 LRSG 64
          LR+ 
Sbjct: 66 LRAN 69


>SPy2027 [TK] COG0745 Response regulators consisting of a CheY-like
          receiver domain and a winged-helix DNA-binding domain
          Length = 217

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 42/65 (64%)

Query: 1  VEDEVHLTEALTQILKKQNYSVDAVHDGRSGLDYAQSGIYDLLLLDIMMPEMDGFTVLKK 60
          VED+  +++ + + LK  NY  D V DG++ LD  Q+  YDL++LDIM+P + G  VLK 
Sbjct: 7  VEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKT 66

Query: 61 LRSGA 65
          +R  +
Sbjct: 67 IRKTS 71


>all1964 [TK] COG0745 Response regulators consisting of a CheY-like
          receiver domain and a winged-helix DNA-binding domain
          Length = 236

 Score = 60.1 bits (144), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 45/69 (65%)

Query: 1  VEDEVHLTEALTQILKKQNYSVDAVHDGRSGLDYAQSGIYDLLLLDIMMPEMDGFTVLKK 60
          V+DEV LT  L+++L ++ Y+V+A ++G+SG + A  G YDLL+LD M+P   G  + ++
Sbjct: 12 VDDEVELTVPLSRVLTREGYTVEAAYEGKSGSEMATVGNYDLLILDWMLPGKTGLEICQE 71

Query: 61 LRSGAYPLP 69
          LR      P
Sbjct: 72 LRRQGKITP 80


>L0131 [TK] COG0745 Response regulators consisting of a CheY-like
          receiver domain and a winged-helix DNA-binding domain
          Length = 230

 Score = 60.1 bits (144), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 28/63 (44%), Positives = 44/63 (69%)

Query: 1  VEDEVHLTEALTQILKKQNYSVDAVHDGRSGLDYAQSGIYDLLLLDIMMPEMDGFTVLKK 60
          +EDE +L   ++  L+ + Y+ +   +GRSGL+ A S  YDL+LLD+M+PE+DGF V ++
Sbjct: 9  IEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARR 68

Query: 61 LRS 63
          LR 
Sbjct: 69 LRK 71


>ML0131 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
          tetrahydromethanopterin reductase and related
          flavin-dependent oxidoreductases
          Length = 346

 Score = 60.1 bits (144), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 8/63 (12%), Positives = 15/63 (23%)

Query: 1  VEDEVHLTEALTQILKKQNYSVDAVHDGRSGLDYAQSGIYDLLLLDIMMPEMDGFTVLKK 60
             EV      T    +QN   DA       +    + I    +  +             
Sbjct: 9  SSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETY 68

Query: 61 LRS 63
          + +
Sbjct: 69 VGN 71


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.138    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 5,298,108
Number of extensions: 168150
Number of successful extensions: 903
Number of sequences better than 1.0e-05: 92
Number of HSP's gapped: 933
Number of HSP's successfully gapped: 92
Length of query: 69
Length of database: 38,378,431
Length adjustment: 41
Effective length of query: 28
Effective length of database: 33,649,737
Effective search space: 942192636
Effective search space used: 942192636
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 109 (46.6 bits)