BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0149.p (219 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin1856 [TK] COG0745 Response regulators consisting of a CheY-li... 253 2e-67 CAC0224 [TK] COG0745 Response regulators consisting of a CheY-li... 252 3e-67 SP1633 [TK] COG0745 Response regulators consisting of a CheY-lik... 238 7e-63 SA0614 [TK] COG0745 Response regulators consisting of a CheY-lik... 200 2e-51 BH0755 [TK] COG0745 Response regulators consisting of a CheY-lik... 192 3e-49 >lin1856 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 225 Score = 253 bits (645), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 118/220 (53%), Positives = 161/220 (73%), Gaps = 2/220 (0%) Query: 2 IVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWCQ 61 IVEDDE IR + LSKW +E+ V F+ ++ +F + +P LV+LDVNLP +DGFYWC Sbjct: 6 IVEDDEVIRDTIRKHLSKWGFEIGVVDDFNNILQEFLSFEPQLVILDVNLPFFDGFYWCN 65 Query: 62 QIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD- 120 QIR VS VPIIFLSSRN MD IM +NMGAD +++KP DL VL+A+++ALLRR Y+Y D Sbjct: 66 QIREVSNVPIIFLSSRNSRMDQIMGMNMGADYYIEKPVDLDVLMARINALLRRTYSYADL 125 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 E+ M H + H+ +++ + EL++NEF+IL +M+ G IVSRD +M+ LW D Sbjct: 126 EEANVMEHNNVFLHIDTNTLTHLEDKIELTKNEFLILYELMKQKGSIVSRDEIMRALWED 185 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 E F+DDNTLTVNV R+R+K+A +GL++FI T+KG GY+IE Sbjct: 186 ESFVDDNTLTVNVVRIRKKLAEIGLDEFIKTKKGQGYMIE 225 >CAC0224 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 252 bits (644), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 113/220 (51%), Positives = 162/220 (73%), Gaps = 2/220 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 MI+ED+EKIR I+ +L KW +E V F+ + + F +P+LVL+D+NLPV DGFYWC Sbjct: 5 MIIEDEEKIRNIIKKSLEKWSFEAHAVEDFNDIFEQFVKVKPNLVLMDINLPVCDGFYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 +IR +SKVP+IFLSSR+ NMDV+MA+NMG DD++ KPF + +L+AK++A+LRR Y+Y + Sbjct: 65 SKIRNISKVPVIFLSSRSSNMDVVMAVNMGGDDYITKPFSIEILMAKINAILRRTYSYSE 124 Query: 121 ESL-QMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 + + + + L N++V Y + EL++NEF I+ +M+N IVSR+ +MQ LW D Sbjct: 125 TEMDTIEFKDVIISLKNNTVYYNENSIELTKNEFKIIYVLMKNHDSIVSREKIMQELWQD 184 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 E FIDDNTLTVN+NRLR+K+ +G+ DFI T KG GY+I+ Sbjct: 185 ESFIDDNTLTVNINRLRKKLKEIGV-DFIKTIKGQGYVIK 223 >SP1633 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 225 Score = 238 bits (606), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 112/217 (51%), Positives = 161/217 (74%), Gaps = 2/217 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 +++EDD+ IR+ + LS+W +EV V F +V+ F S+PHLVL+D+ LP+++G++WC Sbjct: 5 LLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTY-Q 119 Q+IR +SKVPI+FLSSR+Q MD++MAINMGADDFV KPFD VL+AKV LLRR+Y + + Sbjct: 65 QEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGR 124 Query: 120 DESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 DESL + + + + + + Y+GQ L++NEF IL+ + + G IV+RD LM+ LW+ Sbjct: 125 DESL-LEYAGVILNTKSMDLHYQGQVLNLTKNEFQILRVLFEHAGNIVARDDLMRELWNS 183 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGY 216 + FIDDNTL+VNV RLR+K+ GL FI T+KG+GY Sbjct: 184 DFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGY 220 >SA0614 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 224 Score = 200 bits (508), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 98/222 (44%), Positives = 145/222 (65%), Gaps = 9/222 (4%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 ++VEDD + + + L +W + V + F +VMD F + P +V+LDV LP YDGFYWC Sbjct: 4 LLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWC 63 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 +++R VS VPI+FLSSR+ MD +M++ +GADD++QKPF VL+AK+ A+ RR Y + Sbjct: 64 RKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTA 123 Query: 121 ESLQMAHRQLTFH-----LSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQV 175 E R LT+ LS S++ T LS+ E IIL+ ++ +IVSRD+++ Sbjct: 124 EE----KRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIILEILITKKNQIVSRDTIITA 179 Query: 176 LWSDEQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYI 217 LW DE F+ DNTLTVNVNRLR+K++ + ++ I T+ G GY+ Sbjct: 180 LWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYM 221 >BH0755 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 192 bits (488), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 93/224 (41%), Positives = 137/224 (61%), Gaps = 7/224 (3%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 ++EDD K+ I+ K+ YE FD + DF +P LVLLD+NLP +DGFYWC Sbjct: 5 FVIEDDRKMASIICQYFKKYGYEAQYAIDFDMIKQDFLDYRPDLVLLDINLPAFDGFYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 +Q+R +S +PIIFLS+R MD + AI G DD++ KPF L VL+AKV +LRR +Y D Sbjct: 65 RQLRRLSNLPIIFLSARASEMDQVYAIENGGDDYITKPFHLEVLLAKVKGVLRR--SYGD 122 Query: 121 ESLQMAHR-----QLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQV 175 ++ + L F+ +++E GQ E S EF +L + ++ IVSRD L++ Sbjct: 123 YAIPLNQNILEVDGLFFYRDRNTIELNGQKVECSPKEFRLLICLAEHVENIVSRDKLLEA 182 Query: 176 LWSDEQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 +W + F+DDNTL VN+ R RR++ +G+ D I T +G GY ++ Sbjct: 183 IWDEIDFVDDNTLNVNIRRGRRRLEDIGITDAIQTVRGQGYCLK 226 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,589,403 Number of extensions: 533672 Number of successful extensions: 3640 Number of sequences better than 1.0e-05: 330 Number of HSP's gapped: 3427 Number of HSP's successfully gapped: 330 Length of query: 219 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 117 Effective length of database: 26,614,363 Effective search space: 3113880471 Effective search space used: 3113880471 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 114 (48.5 bits)