BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0143.p (1388 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1779_1 [C] COG0243 Anaerobic dehydrogenases, typically selenoc... 518 e-146 alr0612 [C] COG0243 Anaerobic dehydrogenases, typically selenocy... 510 e-144 SMb20986 [C] COG0243 Anaerobic dehydrogenases, typically selenoc... 454 e-127 AGc2380_1 [S] COG1376 Uncharacterized protein conserved in bacteria 431 e-120 AGc2385 [T] COG0784 FOG: CheY-like receiver 431 e-120 >PA1779_1 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 518 bits (1334), Expect = e-146, Method: Compositional matrix adjust. Identities = 0/699 (0%), Positives = 0/699 (0%), Gaps = 32/699 (4%) Query: 3 GNRVVSITGDKEHPANFGRLCTKGSTAAAALTESGRMEYAYKRQDRGAGPERVKIDEAIR 62 S + + A L++S R + + Sbjct: 29 AKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTF 88 Query: 63 DTAQRLRAILEEHGPDALSVYVSGQMSLEAQYLINKLAKGFIRTPNIESNSRLCMAGAGN 122 A + + + + + + + + T + + + + Sbjct: 89 TRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCS 148 Query: 123 GYKLSLGADGPPGSYQDMDKTDLFFVIGANMADCHPILFLRMMDRVKAG---AKLIVVDP 179 ++S + + + + D + L Sbjct: 149 LEQISDFRHEMRYQFWHDFLGNAPTIPPVLYGLNETRPS-QDKDDEQEVFYTTALAQDQA 207 Query: 180 RRTATADKADLFMQIRPGTDXXXXXXXXXXXVKNGHTDPAFIARFTSGFESMEAFLEDYP 239 + + + + Sbjct: 208 DGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPA 267 Query: 240 PDKVSEITGIPEADIRQAAEWIGGAPEWMSCWTMGLNQSIHGTWHTNAICNLHLATGAIC 299 Sbjct: 268 327 Query: 300 RPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSLVSEADRSFIEKLWEIPQGTLRSDASG 359 Sbjct: 328 -- 385 Query: 360 GTISMFESMIAGRIKACWIICTNPVATVPNRKKVIAALEAAELVITQDSFLDTETNRYAD 419 Sbjct: 386 445 Query: 420 ILLPGALWAEGEGVMINSERNLTLMQQAVEPPGEAMPDWQLIARVAAEM------GYAGA 473 Sbjct: 446 505 Query: 474 FAYQSSAEVYAEIQQAWNPKTGYDLRGATYARL-RETPVQWPSAPDQPNDRNPIRYLNRQ 532 Sbjct: 506 ------------ 553 Query: 533 GGTALNEPADGSVPDIVFPTDSGKAVFWARPYMPPAEMPDSDYPFVLNSGRLQHQWHTLT 592 Sbjct: 554 ------- 606 Query: 593 KTGKVPKLNKLNPGPFVEIHPEDAEALGIKDRQPVELRSRRGQAVLPAVLSDRVRPGNCF 652 Sbjct: 607 666 Query: 653 APFHWNDVFGAQLAVNDVTNDAVDPLSLQPELKFCSVSL 691 Sbjct: 667 705 >alr0612 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 510 bits (1314), Expect = e-144, Method: Compositional matrix adjust. Identities = 0/695 (0%), Positives = 0/695 (0%), Gaps = 7/695 (1%) Query: 3 GNRVVSITGDKEHPANFGRLCTKGSTAAAALTESGRMEYAYKRQDRGAGPERVKIDEAIR 62 + H + S +A AL ++ + Sbjct: 36 WHLQRMFKDVTGHAIGAYIRARRLSKSAVAL-RLTARPILDIALQYRFDSQQTFTRAFKK 94 Query: 63 DTAQRLRAILEEHGPDALSVYVSGQMSLEAQYLINKLAKGFIRTPNIESNSRLCMAGAGN 122 AQ A + ++ + + + + + Sbjct: 95 QFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISD 154 Query: 123 GYKLSLGADGPPGSYQDMDKTDLFFVIGANMADCHPILFLRM--MDRVKAGAKLIVVDPR 180 + + + + + V Sbjct: 155 FRHEMRYQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTG 214 Query: 181 RTATADKADLFMQIRPGTDXXXXXXXXXXXVKNGHTDPAFIARFTSGFESMEAFLEDYPP 240 + M G + A Sbjct: 215 HPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGD 274 Query: 241 DKVSEITGIPEADIRQAAEWIGGAPEWMSCWTMGLNQSIHGTWHTNAICNLHLATGAICR 300 Sbjct: 275 334 Query: 301 PGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSLVSEADRSFIEKLWEIPQGTLRSDASGG 360 Sbjct: 335 394 Query: 361 TISMFESMIAGRIKACWIICTNPVATVPNRKKVIAALEAAELVITQDSFLDTETNRYADI 420 Sbjct: 395 454 Query: 421 LLPGALWAEGEGVMINSERNLTLMQQAVEPPGEAMPDWQLIARVAAEMGYAGAFAYQSSA 480 Sbjct: 455 514 Query: 481 EVYAEIQQAWNPKTGYDLRGATYARLR-ETPVQWPSAPDQPNDRNPIRY--LNRQGGTAL 537 Sbjct: 515 - 573 Query: 538 NEPADGSVPDIVFPTDSGKAVFWARPYMPPAEMPDSDYPFVLNSGRLQHQWHTLTKTGKV 597 Sbjct: 574 633 Query: 598 PKLNKLNPGPFVEIHPEDAEALGIKDRQPVELRSRRGQAVLPAVLSDRVRPGNCFAPFHW 657 Sbjct: 634 693 Query: 658 NDVFGAQLAVNDVTNDAVDPLSLQPELKFCSVSLV 692 Sbjct: 694 728 >SMb20986 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 454 bits (1168), Expect = e-127, Method: Compositional matrix adjust. Identities = 0/700 (0%), Positives = 0/700 (0%), Gaps = 47/700 (6%) Query: 1 VSGNRVVSITGDKEHPANFGRLCTKGSTAAAALTESGRMEYAYKRQDRGAGPERVKIDEA 60 +S + V + G + G A + + A A + Sbjct: 22 LSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAV------ALRLTARPILD 75 Query: 61 IRDTAQRLRAILEEHGPDALSVYVSGQMSLEAQYLINKLAKGFIRTPNIESNSRLCMAGA 120 I + ++ + + Sbjct: 76 IALQYRFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLED 135 Query: 121 GNGYKLSLGADGPPGSYQDMDKTDLFFVIGANMADCHPILFLRMMDRVKAG---AKLIVV 177 ++ D + + + I + + K Sbjct: 136 TPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPTIPPVLY-GLNETRPSQDKDDEQ 194 Query: 178 DPRRTATADKADLFMQIRPGTDXXXXXXXXXXXVKNGHTDPAFIARFTSGFESMEAFLED 237 + T + + G G T M Sbjct: 195 EVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLT 254 Query: 238 YPPDKVSEITGIPEADIRQAAEWIGGAPEWMSCWTMGLNQSIHGTWHTNAICNLHLATGA 297 Sbjct: 255 314 Query: 298 ICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSLVSEADRSFIEKLWEIPQGTLRSDA 357 Sbjct: 315 -- 372 Query: 358 SGGTISMFESMIAGRIKACWIICTNPVATVPNRKKVIAALEAAELVITQDSFLDTETNRY 417 Sbjct: 373 432 Query: 418 ADILLPGALWAEGEGVMINSERNLTLMQQAVEPPGEAMPDWQLIARVAAEMGYAGAFAYQ 477 Sbjct: 433 492 Query: 478 SSAEVYAEI----------QQAWNPKTGYDLRGATYARLRETPVQWPSAPDQPNDRNP-- 525 Sbjct: 493 ------ 546 Query: 526 IRYLNRQGGTALNEPADGSVPDIVFPTDSGKAVFWARPYMPPAEMPDSDYPFVLNSGRLQ 585 Sbjct: 547 ----------------- 589 Query: 586 HQWHTLTKTGKVPKLNKLNPGPFVEIHPEDAEALGIKDRQPVELRSRRGQAVLPAVLSDR 645 Sbjct: 590 649 Query: 646 VRPGNCFAPFHWNDVFGAQLAVNDVTNDAVDPLSLQPELK 685 Sbjct: 650 689 >AGc2380_1 [S] COG1376 Uncharacterized protein conserved in bacteria Length = 170 Score = 431 bits (1109), Expect = e-120, Method: Compositional matrix adjust. Identities = 0/616 (0%), Positives = 0/616 (0%), Gaps = 32/616 (5%) Query: 775 IPVLPATAPFEPSTRYFVDGLLAGMFSRTPLPGAEPHSRQVMXXXXXXXXXXXXXXXXXX 834 + + G+L+ P A + Sbjct: 4 GSFVHVVYCVMSLRLRLLTGMLSASILAFPA-LAADSRSLQILVSKSDQ----------- 51 Query: 835 KLPVTILWASQTGNAEGAAIDCAKKLQQAGYDIRLVNMNQYSVSDLAKTRFALFIASTFG 894 L+ + A + ++ +Y S++ F+ Sbjct: 52 ---SLSLYENGEIIATSKVSTGKAGHETPSGIFSILEKRKYHESNIYSAAPMPFMQRLTW 108 Query: 895 AGDPPDNGESFYQALRAENASLLKDLRYAVLAFGDSNYDLFCGFGKNLDTRLEELGASRL 954 +G G+ L ++ + + +E Sbjct: 109 SGIALHEGKVPNYPASHGCVRLPSKFAKSLFGDTRAGVHVIITDRPVSLRFVEHPALFAP 168 Query: 955 LDCAHCDTDYQEQADAWTKDISELLRGFTGRPEXXXXXXXXXXXXXXXXXXXXXXXNPDQ 1014 Sbjct: 169 ----------- 217 Query: 1015 RGYHRNHPVPSRLLFKQQLNKAGSEKETRHYAFDLKSAGVQFEAGDALGVWPVNCPGLVD 1074 Sbjct: 218 277 Query: 1075 DLL-HTLDIEPSAPVMVAGQGELPVNEALHRHFEIARIAPEMLRFIRDRTQNRQLIKLLQ 1133 Sbjct: 278 ---- 333 Query: 1134 SENQTELKQWLWGRQLIDVLQEFPVAL-SAQEFLEQLKPLQPRLYSISSSPKAHPDEVHI 1192 Sbjct: 334 393 Query: 1193 TVSTVRYGNNGNVRKGVCSTFLADLATEDTEIPIFIQKNAHFRPPVNPDAPMIMVGPGTG 1252 Sbjct: 394 453 Query: 1253 IAPFRGFLQERKASGAKGKNWLIFGEQREDSDFYFRGELEAFREEGFLQRLDTAFSRDQA 1312 Sbjct: 454 513 Query: 1313 EKIYVQHRILEHGAKIWAWLQEGAHFYVCGDARQMAKEVDAALKTVIRQHGGRTADEAHD 1372 Sbjct: 514 573 Query: 1373 YVKEMSLTKRYVRDVY 1388 Sbjct: 574 589 >AGc2385 [T] COG0784 FOG: CheY-like receiver Length = 218 Score = 431 bits (1109), Expect = e-120, Method: Compositional matrix adjust. Identities = 0/616 (0%), Positives = 0/616 (0%), Gaps = 32/616 (5%) Query: 775 IPVLPATAPFEPSTRYFVDGLLAGMFSRTPLPGAEPHSRQVMXXXXXXXXXXXXXXXXXX 834 S + L+ S + ++ Sbjct: 4 ARGRDNPNRIIRSRQSMKQELILASSSASRQ-MLMRNAGLTFSAIPADI----------- 51 Query: 835 KLPVTILWASQTGNAEGAAIDCAKKLQQAGYDIRLVNMNQYSVSDLAKTRFALFIASTFG 894 Q + + A +L +A + V +T Sbjct: 52 ---DERALDEQLERDGASPEEVALELARAKALAVSALHPEALVLGCDQTMALGTRVYHKP 108 Query: 895 AGDPPDNGESFYQALRAENASLLKDLRYAVLAFGDSNYDLFCGFGKNLDTRLEELGASRL 954 + + + L + + + Sbjct: 109 KNMAEAATHLLSLSGKVHRLNSAAVLVHNGKVVWQTVSSAELAVRTLSAEFVSRHLQRVG 168 Query: 955 LDCAHCDTDYQEQADAWTKDISELLRGFTGRPEXXXXXXXXXXXXXXXXXXXXXXXNPDQ 1014 YQ + + S FT Sbjct: 169 EKALSSVGAYQLEREGIQLFTSIEGDYFTILGLPLLPLLSKLRDMDVI-----------D 217 Query: 1015 RGYHRNHPVPSRLLFKQQLNKAGSEKETRHYAFDLKSAGVQFEAGDALGVWPVNCPGLVD 1074 Sbjct: 218 277 Query: 1075 DLL-HTLDIEPSAPVMVAGQGELPVNEALHRHFEIARIAPEMLRFIRDRTQNRQLIKLLQ 1133 Sbjct: 278 ---- 333 Query: 1134 SENQTELKQWLWGRQLIDVLQEFPVAL-SAQEFLEQLKPLQPRLYSISSSPKAHPDEVHI 1192 Sbjct: 334 393 Query: 1193 TVSTVRYGNNGNVRKGVCSTFLADLATEDTEIPIFIQKNAHFRPPVNPDAPMIMVGPGTG 1252 Sbjct: 394 453 Query: 1253 IAPFRGFLQERKASGAKGKNWLIFGEQREDSDFYFRGELEAFREEGFLQRLDTAFSRDQA 1312 Sbjct: 454 513 Query: 1313 EKIYVQHRILEHGAKIWAWLQEGAHFYVCGDARQMAKEVDAALKTVIRQHGGRTADEAHD 1372 Sbjct: 514 573 Query: 1373 YVKEMSLTKRYVRDVY 1388 Sbjct: 574 589 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 106,008,123 Number of extensions: 4477490 Number of successful extensions: 13700 Number of sequences better than 1.0e-05: 145 Number of HSP's gapped: 13375 Number of HSP's successfully gapped: 189 Length of query: 1388 Length of database: 38,378,431 Length adjustment: 119 Effective length of query: 1269 Effective length of database: 24,653,685 Effective search space: 31285526265 Effective search space used: 31285526265 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 122 (51.6 bits)