BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0108.p (412 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_kinB [T] COG0642 Signal transduction histidine kinase 157 3e-38 BS_kinC_2 [T] COG0642 Signal transduction histidine kinase 149 7e-36 BS_kinA_3 [T] COG0642 Signal transduction histidine kinase 142 8e-34 atoS_3 [T] COG0642 Signal transduction histidine kinase 114 4e-25 BB0764_2 [T] COG0642 Signal transduction histidine kinase 104 3e-22 >BS_kinB [T] COG0642 Signal transduction histidine kinase Length = 429 Score = 157 bits (398), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 91/228 (39%), Positives = 133/228 (58%), Gaps = 6/228 (2%) Query: 188 RDRILQSERLNVVSELAASVSHEIRNPLTVTSGFLQLLNKSNTITPEEKG-YVELSLLEL 246 R +++ SE++ +VSELAASV+HE+RNPLTV GF+QLL T+ + Y +L L EL Sbjct: 201 RSQLIHSEKMTIVSELAASVAHEVRNPLTVVRGFVQLLFNDETLQNKSSADYKKLVLSEL 260 Query: 247 NRAEKIVSDYLSFAKPQSDNMVCSNMKAEAEYTKNIIMPYATIHKVDVQFNFNNTLNKCY 306 +RA+ I+++YL AK Q ++ A + T ++++ YA V V+ L Sbjct: 261 DRAQGIITNYLDMAKQQLYEKEVFDLSALIKETSSLMVSYANYKSVTVEAETEPDLLIYG 320 Query: 307 DKNQIQQCLINLYKNGIEAMREKDGGTLTIDISEKK--QNIVISIQDTGIGMTKEEISRL 364 D +++Q +INL KN IEA+ G I IS K+ I+I+I D G+GMT ++ +L Sbjct: 321 DATKLKQAVINLMKNSIEAVPHGKG---MIHISAKRNGHTIMINITDNGVGMTDHQMQKL 377 Query: 365 GKPYYSTKEEGTGLGMLMAYSAINKVKGIIEVESEKGKGTTFLITIPT 412 G+PYYS K GTGLG+ + +S I G I S KGTT I +P Sbjct: 378 GEPYYSLKTNGTGLGLTVTFSIIEHHHGTISFNSSFQKGTTVTIKLPA 425 >BS_kinC_2 [T] COG0642 Signal transduction histidine kinase Length = 248 Score = 149 bits (376), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 83/222 (37%), Positives = 139/222 (62%), Gaps = 9/222 (4%) Query: 193 QSERLNVVSELAASVSHEIRNPLTVTSGFLQLLNKSNTITPEEKGYVELSLLELNRAEKI 252 +S++L++ SELAA ++HE+RNPLT SGFLQ++ T P+ K Y ++ E+ R + + Sbjct: 28 ESQKLSITSELAAGIAHEVRNPLTSVSGFLQIMK---TQYPDRKDYFDIIFSEIKRIDLV 84 Query: 253 VSDYLSFAKPQSDNMVCSNMKAEAEYTKNIIMPYATIHKVDVQFNFNNTLNKCY---DKN 309 +S+ L AKPQ+ + + ++ A + + ++ NF T + C D+N Sbjct: 85 LSELLLLAKPQAITFKTHQLNEILKQVTTLLDTNAILSNIVIEKNFKET-DGCMINGDEN 143 Query: 310 QIQQCLINLYKNGIEAMREKDGGTLTIDISEKKQNIVISIQDTGIGMTKEEISRLGKPYY 369 Q++Q IN+ KNGIEAM + GG +TI ++ + VIS++D G GM +E++ ++GKP+Y Sbjct: 144 QLKQVFINIIKNGIEAMPK--GGVVTISTAKTASHAVISVKDEGNGMPQEKLKQIGKPFY 201 Query: 370 STKEEGTGLGMLMAYSAINKVKGIIEVESEKGKGTTFLITIP 411 STKE+GTGLG+ + + + G +++ESE GKG+ F + +P Sbjct: 202 STKEKGTGLGLPICLRILKEHDGELKIESEAGKGSVFQVVLP 243 >BS_kinA_3 [T] COG0642 Signal transduction histidine kinase Length = 236 Score = 142 bits (359), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 82/229 (35%), Positives = 145/229 (63%), Gaps = 9/229 (3%) Query: 186 KNRDRILQSERLNVVSELAASVSHEIRNPLTVTSGFLQLLNKSNTITPEEKGYVELSLLE 245 + + +L+SE+L++ +LAA ++HEIRNPLT GFLQL+ T+ E Y ++ E Sbjct: 12 QTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKP--TMEGNEH-YFDIVFSE 68 Query: 246 LNRAEKIVSDYLSFAKPQSDNMVCS--NMKAEAEYTKNIIMPYATIHKVDVQFNFN-NTL 302 L+R E I+S+ L AKPQ N V N+K ++ A ++ + ++ ++ +++ Sbjct: 69 LSRIELILSELLMLAKPQQ-NAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSI 127 Query: 303 NKCYDKNQIQQCLINLYKNGIEAMREKDGGTLTIDISEKKQNIVISIQDTGIGMTKEEIS 362 D+NQ++Q INL KN +E+M DGGT+ I I+E + ++ ++++D G G+ ++ ++ Sbjct: 128 YINGDQNQLKQVFINLIKNAVESM--PDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLN 185 Query: 363 RLGKPYYSTKEEGTGLGMLMAYSAINKVKGIIEVESEKGKGTTFLITIP 411 R+G+P+ +TKE+GTGLG+++ ++ I +G+I V+S KGT F I+ P Sbjct: 186 RIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFP 234 >atoS_3 [T] COG0642 Signal transduction histidine kinase Length = 278 Score = 114 bits (284), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 127/250 (50%), Gaps = 10/250 (4%) Query: 166 THGAVMSXXXXXXXXXXXXXKNRDRILQSERLNVVSELAASVSHEIRNPLTVTSGFLQLL 225 THG ++ R R+ Q+ERL + EL A V+HE+RNPLT G++Q+L Sbjct: 26 THGEMIGALVIFSDLTARKETQR-RMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQIL 84 Query: 226 NKSNTITPEEKGYVELSLLELNRAEKIVSDYLSFAKPQSDNMVCSNMKAEAEYTKNIIMP 285 + T P + Y+ + L E++ K++ L F++P+ ++ A E T ++ Sbjct: 85 -RQQTSDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQT 143 Query: 286 YATIHKVDVQFNFNNTLNKC-YDKNQIQQCLINLYKNGIEAMREKDGGTLTIDI---SEK 341 +VD +N L+ D+ ++Q L+N+ N ++A+ + G + I S+ Sbjct: 144 AGVQARVDFISELDNELSPINADRELLKQVLLNILINAVQAISAR--GKIRIQTWQYSDS 201 Query: 342 KQNIVISIQDTGIGMTKEEISRLGKPYYSTKEEGTGLGMLMAYSAINKVKGIIEVESEKG 401 +Q ISI+D G G+ ++ P+++TK GTGLG+ ++ IN +G I V S G Sbjct: 202 QQ--AISIEDNGCGIDLSLQKKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPG 259 Query: 402 KGTTFLITIP 411 G TF + +P Sbjct: 260 YGATFTLILP 269 >BB0764_2 [T] COG0642 Signal transduction histidine kinase Length = 282 Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 75/217 (34%), Positives = 119/217 (54%), Gaps = 12/217 (5%) Query: 204 AASVSHEIRNPLTVTSGFLQLLNKSNTITPEEKG----YVELSLLELNRAEKIVSDYLSF 259 A +++HEI+NPL LQLL K + G Y ++ E+NR +KIV+++L Sbjct: 57 ARNIAHEIKNPLGAIDINLQLLKKEIEKQKMKNGKAENYFKVIKEEINRVDKIVTEFLLT 116 Query: 260 AKPQSDNMVCSNMKAEAEYTKNIIMPYATIHKVDVQFNFNNTLNKCYDKNQIQQCLINLY 319 +P N+ ++K ++ P + + N N N D+ ++Q +IN+ Sbjct: 117 VRPIKINLQEKDIKQVIGSVCELLNPGLENKHIKLLLNLNKISNILIDEKLLKQVIINIV 176 Query: 320 KNGIEAMRE--KDGGTLTIDISEKKQNIVISIQDTGIGM---TKEEISRLGKPYYSTKEE 374 KN EA+ E K+ + I + EK I I+I+D G G+ KEEI KP +STKE+ Sbjct: 177 KNAEEALLETKKEIKKIEIFLFEKDNKIHINIKDNGNGIKDGVKEEIF---KPQFSTKEK 233 Query: 375 GTGLGMLMAYSAINKVKGIIEVESEKGKGTTFLITIP 411 G+G+G+ ++Y I ++ G I VES++GKGT F IT+P Sbjct: 234 GSGIGLTISYKIIKELGGEIFVESKEGKGTIFTITLP 270 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.138 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,869,266 Number of extensions: 937640 Number of successful extensions: 3082 Number of sequences better than 1.0e-05: 200 Number of HSP's gapped: 2865 Number of HSP's successfully gapped: 200 Length of query: 412 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 303 Effective length of database: 25,807,025 Effective search space: 7819528575 Effective search space used: 7819528575 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 117 (49.7 bits)