BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0094.p (246 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yurK [K] COG2188 Transcriptional regulators 216 3e-56 ZyhfR [K] COG2188 Transcriptional regulators 190 2e-48 ECs4225 [K] COG2188 Transcriptional regulators 190 2e-48 yhfR [K] COG2188 Transcriptional regulators 189 3e-48 ZyhfR [K] COG2188 Transcriptional regulators 189 3e-48 >BS_yurK [K] COG2188 Transcriptional regulators Length = 242 Score = 216 bits (550), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 106/238 (44%), Positives = 152/238 (63%) Query: 3 LNNLSQKPLYFQLKQILKEDVERGVYKAGQQLPPEAELCEMYGVSRITARRAITDLVEEG 62 LNN S PLY QLKQI+ +D+++GVY +LP E ELC Y VSRIT R+AI DLVEEG Sbjct: 2 LNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEEG 61 Query: 63 ILHRQQGKGTYVKEAKVMRELISVGGFSELTTASGKTPSSQILFNKVIQADEKLAKTFNI 122 L RQQGKGT+VK K+ RELI+V G+SE ++GK P +L + +I A + +A+ I Sbjct: 62 YLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQI 121 Query: 123 APHDPILNVHRLLFIDNEPFIIETSYYPLNLLPDLEKHIGESASTYSILKKRYNVELCRS 182 P P++ + R+L+ D++P E ++YPL+L P ++ I + S + ILK++Y V + Sbjct: 122 QPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTHN 181 Query: 183 QKTLEVVAASEYDADLFRCDRGTPLFAIEKASFDKTDRLIHLSNSLYMTNKVIFTIDT 240 K L VV A + ++ CD G LF I+K +F D+ I+ S L TN+V FTI++ Sbjct: 182 TKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQPIYCSLFLMHTNRVTFTINS 239 >ZyhfR [K] COG2188 Transcriptional regulators Length = 265 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 87/236 (36%), Positives = 148/236 (62%), Gaps = 1/236 (0%) Query: 7 SQKPLYFQLKQILKEDVERGVYKAGQQLPPEAELCEMYGVSRITARRAITDLVEEGILHR 66 S + LY ++Q L +D+ +GVY+AGQQ+P E ELC Y VSRIT R+AI+DLV +G+L R Sbjct: 30 SHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIR 89 Query: 67 QQGKGTYVKEAKVMRELISVGGFSELTTASGKTPSSQILFNKVIQADEKLAKTFNIAPHD 126 QGKGT+V+ KV L++V GF++ + GK +++ + + A + NI + Sbjct: 90 WQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERVSA-APFCEKLNIPGNS 148 Query: 127 PILNVHRLLFIDNEPFIIETSYYPLNLLPDLEKHIGESASTYSILKKRYNVELCRSQKTL 186 + ++ R++++D EP I++S+ PL+ PD ++ E +STY + ++R++ + +KT+ Sbjct: 149 EVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTI 208 Query: 187 EVVAASEYDADLFRCDRGTPLFAIEKASFDKTDRLIHLSNSLYMTNKVIFTIDTKK 242 ++ AA+ A +C+ G PLF I K +FD+ D+ +H+S N++ TID K+ Sbjct: 209 DIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDNKR 264 >ECs4225 [K] COG2188 Transcriptional regulators Length = 265 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 88/236 (37%), Positives = 148/236 (62%), Gaps = 1/236 (0%) Query: 7 SQKPLYFQLKQILKEDVERGVYKAGQQLPPEAELCEMYGVSRITARRAITDLVEEGILHR 66 S + LY ++Q L +D+ +GVY+AGQQ+P E ELC Y VSRIT R+AI+DLV +G+L R Sbjct: 30 SHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIR 89 Query: 67 QQGKGTYVKEAKVMRELISVGGFSELTTASGKTPSSQILFNKVIQADEKLAKTFNIAPHD 126 QGKGT+V+ KV L++V GF++ + GK +++ + I A + NI + Sbjct: 90 WQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERISA-APFCEKLNIPGNS 148 Query: 127 PILNVHRLLFIDNEPFIIETSYYPLNLLPDLEKHIGESASTYSILKKRYNVELCRSQKTL 186 + ++ R++++D EP I++S+ PL+ PD ++ E +STY + ++R++ + +KT+ Sbjct: 149 EVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTI 208 Query: 187 EVVAASEYDADLFRCDRGTPLFAIEKASFDKTDRLIHLSNSLYMTNKVIFTIDTKK 242 ++ AA+ A +C+ G PLF I K +FD+ D+ +H+S N++ TID K+ Sbjct: 209 DIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDNKR 264 >yhfR [K] COG2188 Transcriptional regulators Length = 265 Score = 189 bits (480), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 87/236 (36%), Positives = 148/236 (62%), Gaps = 1/236 (0%) Query: 7 SQKPLYFQLKQILKEDVERGVYKAGQQLPPEAELCEMYGVSRITARRAITDLVEEGILHR 66 S + LY ++Q L +D+ +GVY+AGQQ+P E ELC Y VSRIT R+AI+DLV +G+L R Sbjct: 30 SHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIR 89 Query: 67 QQGKGTYVKEAKVMRELISVGGFSELTTASGKTPSSQILFNKVIQADEKLAKTFNIAPHD 126 QGKGT+V+ KV L++V GF++ + GK +++ + + A + NI + Sbjct: 90 WQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERVSA-APFCEKLNIPGNS 148 Query: 127 PILNVHRLLFIDNEPFIIETSYYPLNLLPDLEKHIGESASTYSILKKRYNVELCRSQKTL 186 + ++ R++++D EP I++S+ PL+ PD ++ E +STY + ++R++ + +KT+ Sbjct: 149 EVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTI 208 Query: 187 EVVAASEYDADLFRCDRGTPLFAIEKASFDKTDRLIHLSNSLYMTNKVIFTIDTKK 242 ++ AA+ A +C+ G PLF I K +FD+ D+ +H+S N++ TID K+ Sbjct: 209 DIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDNKR 264 Score = 189 bits (480), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 87/236 (36%), Positives = 148/236 (62%), Gaps = 1/236 (0%) Query: 7 SQKPLYFQLKQILKEDVERGVYKAGQQLPPEAELCEMYGVSRITARRAITDLVEEGILHR 66 S + LY ++Q L +D+ +GVY+AGQQ+P E ELC Y VSRIT R+AI+DLV +G+L R Sbjct: 30 SHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIR 89 Query: 67 QQGKGTYVKEAKVMRELISVGGFSELTTASGKTPSSQILFNKVIQADEKLAKTFNIAPHD 126 QGKGT+V+ KV L++V GF++ + GK +++ + + A + NI + Sbjct: 90 WQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERVSA-APFCEKLNIPGNS 148 Query: 127 PILNVHRLLFIDNEPFIIETSYYPLNLLPDLEKHIGESASTYSILKKRYNVELCRSQKTL 186 + ++ R++++D EP I++S+ PL+ PD ++ E +STY + ++R++ + +KT+ Sbjct: 149 EVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTI 208 Query: 187 EVVAASEYDADLFRCDRGTPLFAIEKASFDKTDRLIHLSNSLYMTNKVIFTIDTKK 242 ++ AA+ A +C+ G PLF I K +FD+ D+ +H+S N++ TID K+ Sbjct: 209 DIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDNKR 264 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,257,758 Number of extensions: 723862 Number of successful extensions: 2999 Number of sequences better than 1.0e-05: 147 Number of HSP's gapped: 2935 Number of HSP's successfully gapped: 147 Length of query: 246 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 142 Effective length of database: 26,383,695 Effective search space: 3746484690 Effective search space used: 3746484690 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)