BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0076.p (507 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA2155 [R] COG0579 Predicted dehydrogenase 616 e-176 PA3452 [R] COG0579 Predicted dehydrogenase 550 e-156 PA4640 [R] COG0579 Predicted dehydrogenase 546 e-155 SA2400 [R] COG0579 Predicted dehydrogenase 546 e-155 ZyojH [R] COG0579 Predicted dehydrogenase 521 e-147 >SA2155 [R] COG0579 Predicted dehydrogenase Length = 511 Score = 616 bits (1589), Expect = e-176, Method: Compositional matrix adjust. Identities = 289/489 (59%), Positives = 373/489 (76%) Query: 2 SNRQKTDVILIGAGIMSATLGSLLKELVPDWKITVFERRAGAGEESSNEWNNAGTGHSSL 61 + KTDVILIG GIMSATLG+LLKEL P+ I VFE+ A GEESSN WNNAGTGHS+L Sbjct: 22 TQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSAL 81 Query: 62 CELNYTVEQPDGSIDISKAIKVNEEYQFSKQFWSYLVKSKRIQHPQDFIVPVPHMSFVQG 121 CELNYT E DG++D SKAIK+NE+YQ SKQFW+YLVK+ ++ +P FI VPHMSFV G Sbjct: 82 CELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIG 141 Query: 122 EADVTFLKKRFEALSQNPLFQGMEFSEDPEQLMEWIPLMMKDRRINQPIAATRIESGTDV 181 E +V F+K R L ++ LF+ M+ S+D E++ W+PLM++ R+ ++PIA T E+GTDV Sbjct: 142 EDNVAFIKSRVATLKKSVLFEKMKLSQDEEEMKSWVPLMIEGRKSDEPIALTYDETGTDV 201 Query: 182 NFGALTRILFDHLQSNNTDIRYQHNVDDIKRAGDGSWDLKVRNLENGTTTRHSAKFVFIG 241 NFGALT LF++L+ I+Y+ NV DIK+ G+W +KV++LE TT + + FVFIG Sbjct: 202 NFGALTAKLFENLEQRGVGIQYKQNVLDIKKQKSGAWLVKVKDLETNETTTYESDFVFIG 261 Query: 242 GGGGSLHLLQKSGIPEGKGIGGFPVSGLFMVCQKPDIVAQHHAKVYGKAALGAPPMSVPH 301 GG SL LLQK+GI + K IGGFPVSGLF+ C +++ +HHAKVYGKAA+GAPPMSVPH Sbjct: 262 AGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPH 321 Query: 302 LDTRVIDKKESLFFGPFAGFSPKFLKYGSVFDLITSVKPGNLTTMLAAGAKNLSLTKYLI 361 LDTR +D K SL FGPFAGFSPKFLK GS DLI SVKP N+ TML+AG K +SLTKYL+ Sbjct: 322 LDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLV 381 Query: 362 GQVMLSKDQRIEALREFVPGAQSGDWDLVVAGQRVQIIKDTAAGKGTLQFGTEVISSADG 421 Q+MLS D+R++ LR F P A++ DW+++ AGQRVQ+IKDT KG LQFGTEVI+S DG Sbjct: 382 SQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIKDTEDSKGNLQFGTEVITSDDG 441 Query: 422 SIAALLGASPGASTAVSVMLEVIGKCFPQQLKAWEPKIKEMIPAYGVTLMENPKLINEIQ 481 ++AALLGASPGASTAV +M +V+ +C+ + K WEPKIKEM+P++G L ++ L ++I Sbjct: 442 TLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHKIN 501 Query: 482 KLTDRSLNL 490 + + L + Sbjct: 502 EEVTKYLQV 510 >PA3452 [R] COG0579 Predicted dehydrogenase Length = 523 Score = 550 bits (1416), Expect = e-156, Method: Compositional matrix adjust. Identities = 272/494 (55%), Positives = 346/494 (70%), Gaps = 4/494 (0%) Query: 1 MSNRQKTDVILIGAGIMSATLGSLLKELVPDWKITVFERRAGAGEESSNEWNNAGTGHSS 60 + + + DV+LIG GIMSATLG+ L EL P W I + ER EESSN WNNAGTGHS+ Sbjct: 21 VESEKPVDVLLIGGGIMSATLGTYLNELEPGWTIEMVERLDKVAEESSNGWNNAGTGHSA 80 Query: 61 LCELNYTVEQPDGSIDISKAIKVNEEYQFSKQFWSYLVKSKRIQHPQDFIVPVPHMSFVQ 120 CELNYT E DGS+DISKA+ +NE ++ SKQFW+Y V K + P+ FI VPHMSFV Sbjct: 81 FCELNYTSEAADGSMDISKAVAINENFEISKQFWAYQVDRKVLNDPKSFINNVPHMSFVW 140 Query: 121 GEADVTFLKKRFEALSQNPLFQGMEFSEDPEQLMEWIPLMMKDRRINQPIAATRIESGTD 180 G+ +V FLKKR AL + LF+GME+SEDPEQ+ +W+PL+M+ R Q IAATR+ GTD Sbjct: 141 GDDNVAFLKKRHAALQHSSLFRGMEYSEDPEQIKQWVPLVMEGREPGQKIAATRMSIGTD 200 Query: 181 VNFGALTRILFDHLQSNNT-DIRYQHNVDDIKRAGDGSWDLKVRNLENGTT-TRHSAKFV 238 VNFG +TR L L + +T +R QH V D+KR D +W + + +L NG T A+FV Sbjct: 201 VNFGEITRQLVGSLSAKDTFKLRLQHEVRDLKRNDDNTWTVTMADLANGDKETSVKARFV 260 Query: 239 FIGGGGGSLHLLQKSGIPEGKGIGGFPVSGLFMVCQKPDIVAQHHAKVYGKAALGAPPMS 298 FIG GGG+L LLQ SGIPE +G GFPV G F+ PD+V +H AKVYGKA++G+PPMS Sbjct: 261 FIGAGGGALKLLQMSGIPEAEGYAGFPVGGSFLATTNPDVVKRHLAKVYGKASVGSPPMS 320 Query: 299 VPHLDTRVIDKKESLFFGPFAGFSPKFLKYGSVFDLITSVKPGNLTTMLAAGAKNLSLTK 358 VPHLDTR+ID K L FGPFA FS KFLK GS++DL SV GN+ M AG N L++ Sbjct: 321 VPHLDTRMIDGKPVLLFGPFATFSTKFLKNGSLWDLPGSVTSGNIGPMFNAGIDNFDLSQ 380 Query: 359 YLIGQVMLSKDQRIEALREFVPGAQSGDWDLVVAGQRVQIIKDTAAGKGTLQFGTEVISS 418 YLIGQ+MLS+D R+ +LRE+ P A+ DW LV AGQRVQIIK A G LQFGTEV+++ Sbjct: 381 YLIGQLMLSQDDRMASLREYFPEARDEDWKLVQAGQRVQIIKKDAEKGGVLQFGTEVVTA 440 Query: 419 ADGSIAALLGASPGASTAVSVMLEVIGKCFPQQLKA--WEPKIKEMIPAYGVTLMENPKL 476 ADGS+AALLGASPGASTA +ML V+ K F ++ W+ ++KE++P+YG L + +L Sbjct: 441 ADGSVAALLGASPGASTAAPIMLSVLEKAFKDKVATPEWQARLKEIVPSYGRKLNNDIEL 500 Query: 477 INEIQKLTDRSLNL 490 N + + L L Sbjct: 501 TNSTRAWSSERLQL 514 >PA4640 [R] COG0579 Predicted dehydrogenase Length = 507 Score = 546 bits (1408), Expect = e-155, Method: Compositional matrix adjust. Identities = 271/507 (53%), Positives = 354/507 (69%), Gaps = 7/507 (1%) Query: 2 SNRQKTDVILIGAGIMSATLGSLLKELVPDWKITVFERRAGAGEESSNEWNNAGTGHSSL 61 ++ + D++L+GAGIMSATL LLKEL P+ K+ V E + ESSN WNNAGTGH+ L Sbjct: 4 NDHETVDMLLVGAGIMSATLAVLLKELDPNLKMEVVELQESGAIESSNPWNNAGTGHAGL 63 Query: 62 CELNYTVEQPDGSIDISKAIKVNEEYQFSKQFWSYLVKSKRIQHPQDFIVPVPHMSFVQG 121 CELNYT + DGSIDI KA+ +N ++ SKQFWS+LV P+ FI PVPH+SFV+G Sbjct: 64 CELNYTPQSADGSIDIKKAVGINTMFEVSKQFWSHLVAKGTFGSPKTFINPVPHLSFVRG 123 Query: 122 EADVTFLKKRFEALSQNPLFQGMEFSEDPEQLMEWIPLMMKDRRINQPIAATRIESGTDV 181 + +LKKRFE+L+++ F+ M +SED L EW+PLMM R ++ IAATR+E GTDV Sbjct: 124 SEGIAYLKKRFESLTKHHAFETMVYSEDKATLAEWMPLMMPGRPADEAIAATRVEGGTDV 183 Query: 182 NFGALTRILFDHL-QSNNTDIRYQHNVDDIKRAGDGSWDLKVRNLENGTTTRHSAKFVFI 240 NFGALT L HL Q IRY V ++RA +G W + V++ NG A+FVF+ Sbjct: 184 NFGALTNQLLQHLAQQPGAQIRYNQKVTHLRRADNG-WRVTVKDTRNGGDREIQARFVFL 242 Query: 241 GGGGGSLHLLQKSGIPEGKGIGGFPVSGLFMVCQKPDIVAQHHAKVYGKAALGAPPMSVP 300 G GGG+L LLQ SGIPEGKG GGFPVSG ++ C P+IV QH AKVY +A +G+PPMSVP Sbjct: 243 GAGGGALPLLQLSGIPEGKGFGGFPVSGQWLRCDNPEIVKQHQAKVYSQAEVGSPPMSVP 302 Query: 301 HLDTRVIDKKESLFFGPFAGFSPKFLKYGSVFDLITSVKPGNLTTMLAAGAKNLSLTKYL 360 HLDTRV+D K+SL FGP+AGFS KFL++GS DL SV+PGN+ ML+ N+ LT+YL Sbjct: 303 HLDTRVVDGKKSLLFGPYAGFSTKFLRHGSFLDLPLSVRPGNILPMLSVARDNMDLTRYL 362 Query: 361 IGQVMLSKDQRIEALREFVPGAQSGDWDLVVAGQRVQIIKDTAAGKGTLQFGTEVISSAD 420 IGQVM S +QR+EALR+F P A++ DW L VAGQRVQIIK G LQFGTE++++ D Sbjct: 363 IGQVMQSPEQRLEALRKFYPEARAEDWRLEVAGQRVQIIKKDPKKGGILQFGTELVAAHD 422 Query: 421 GSIAALLGASPGASTAVSVMLEVIGKCFPQQLKA--WEPKIKEMIPAYGVTLMENPKLIN 478 GSIAALLGASPGAS VS+ML +I +CFP+Q ++ W K+KE+ PA L + +L Sbjct: 423 GSIAALLGASPGASVTVSIMLGLIERCFPEQARSPEWSAKLKEIFPAREKELESDAELYR 482 Query: 479 EIQKLTDRSLNLTSRAGEVEKKAPISS 505 + L LT++ + +AP+++ Sbjct: 483 SVSSRCSEVLELTAKN---DVQAPVNA 506 >SA2400 [R] COG0579 Predicted dehydrogenase Length = 498 Score = 546 bits (1407), Expect = e-155, Method: Compositional matrix adjust. Identities = 262/493 (53%), Positives = 353/493 (71%), Gaps = 3/493 (0%) Query: 1 MSNRQKTDVILIGAGIMSATLGSLLKELVPDWKITVFERRAGAGEESSNEWNNAGTGHSS 60 M+ D++LIGAG++S T GS+LKE+ PDW I V+ER ESSNE NNAGTGH++ Sbjct: 1 MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAA 60 Query: 61 LCELNYTVEQPDGSIDISKAIKVNEEYQFSKQFWSYLVKSKRIQHPQDFIVPVPHMSFVQ 120 LCELNYTV QPDGSIDI KA +NEE++ SKQFW +LVKS I++P++FI P+PH+S+V+ Sbjct: 61 LCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVR 120 Query: 121 GEADVTFLKKRFEALSQNPLFQGMEFSEDPEQLMEWIPLMMKDRRINQPI-AATRIESGT 179 G+ +V FLK R+EA+ P+F +E++ED E + +WIPLMMK R N I AA++I+ GT Sbjct: 121 GKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGT 180 Query: 180 DVNFGALTRILFDHLQSN-NTDIRYQHNVDDIKRAGDGSWDLKVRNLENGTTTRHSAKFV 238 DVNFG LTR + ++++ N +++ H V D ++ +G W++ V+N G + +V Sbjct: 181 DVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYV 240 Query: 239 FIGGGGGSLHLLQKSGIPEGKGIGGFPVSGLFMVCQKPDIVAQHHAKVYGKAALGAPPMS 298 FIG GGG++ LLQK+GIPE K +GGFP+SG F+ C P ++ QH AKVYGK G PPM+ Sbjct: 241 FIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMT 300 Query: 299 VPHLDTRVIDKKESLFFGPFAGFSPKFLKYGSVFDLITSVKPGNLTTMLAAGAKNLSLTK 358 VPHLDTR ID + +L FGPFA PKFLK GS DL SVK N+TT+LAA KNL L K Sbjct: 301 VPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIK 360 Query: 359 YLIGQVMLSKDQRIEALREFVPGAQSGDWDLVVAGQRVQIIKDTAA-GKGTLQFGTEVIS 417 Y QV+++K+ + LR F P A++ DW L AG+RVQ+IKDT GKG +QFGTEV++ Sbjct: 361 YSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVN 420 Query: 418 SADGSIAALLGASPGASTAVSVMLEVIGKCFPQQLKAWEPKIKEMIPAYGVTLMENPKLI 477 S D ++ ALLG SPGAST+VSV LEV+ + FP+ W PKIK+MIP+YG +L+E+ KL+ Sbjct: 421 SQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLM 480 Query: 478 NEIQKLTDRSLNL 490 +I+K T + L L Sbjct: 481 RKIRKQTSKDLEL 493 >ZyojH [R] COG0579 Predicted dehydrogenase Length = 548 Score = 521 bits (1341), Expect = e-147, Method: Compositional matrix adjust. Identities = 258/494 (52%), Positives = 337/494 (68%), Gaps = 10/494 (2%) Query: 2 SNRQKTDVILIGAGIMSATLGSLLKELVPDWKITVFERRAGAGEESSNEWNNAGTGHSSL 61 S Q+TDV+LIG GIMSATLG+ L+EL P+W +T+ ER G +ESSN WNNAGTGHS+L Sbjct: 27 SEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSAL 86 Query: 62 CELNYTVEQPDGSIDISKAIKVNEEYQFSKQFWSYLVKSKRIQHPQDFIVPVPHMSFVQG 121 ELNYT + DGSI I KA+ +NE +Q S+QFW++ V+ ++ P+ FI VPHMSFV G Sbjct: 87 MELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWG 146 Query: 122 EADVTFLKKRFEALSQNPLFQGMEFSEDPEQLMEWIPLMMKDRRINQPIAATRIESGTDV 181 E +V FL+ R+ AL Q+ LF+GM +SED Q+ EW PL+M+ R Q +AATR E GTDV Sbjct: 147 EDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDV 206 Query: 182 NFGALTRILFDHLQS-NNTDIRYQHNVDDIKRAGDGSWDLKVRNLENGTTTRHSAKFVFI 240 N+G +TR L LQ +N ++ V +KR D +W + V +L+NGT AKFVFI Sbjct: 207 NYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFI 266 Query: 241 GGGGGSLHLLQKSGIPEGKGIGGFPVSGLFMVCQKPDIVAQHHAKVYGKAALGAPPMSVP 300 G GG +L LLQ+SGIPE K GFPV G F+V + PD+V H AKVYGKA++GAPPMSVP Sbjct: 267 GAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVP 326 Query: 301 HLDTRVIDKKESLFFGPFAGFSPKFLKYGSVFDLITSVKPGNLTTMLAAGAKNLSLTKYL 360 H+DTRV+D K + FGPFA FS KFLK GS++DL++S N+ M+ G N L KYL Sbjct: 327 HIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYL 386 Query: 361 IGQVMLSKDQRIEALREFVPGAQSGDWDLVVAGQRVQIIKDTAAGKGTLQFGTEVISSAD 420 + QVMLS++ R EAL+E+ P A+ DW L AGQRVQIIK A G L+ GTEV+S Sbjct: 387 VSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQ 446 Query: 421 GSIAALLGASPGASTAVSVMLEVIGKCFPQQLKA--WEPKIKEMIPAYGVTLMENPKLIN 478 G+IAALLGASPGASTA +ML ++ K F ++ + W+ +K ++P+YG + +N Sbjct: 447 GTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYG-------RKLN 499 Query: 479 EIQKLTDRSLNLTS 492 T+R L TS Sbjct: 500 GDVAATERELQYTS 513 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,379,134 Number of extensions: 1593513 Number of successful extensions: 3147 Number of sequences better than 1.0e-05: 9 Number of HSP's gapped: 3127 Number of HSP's successfully gapped: 9 Length of query: 507 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 396 Effective length of database: 25,576,357 Effective search space: 10128237372 Effective search space used: 10128237372 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 118 (50.1 bits)