BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0066.p (310 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase ... 288 5e-78 lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase ... 266 2e-71 BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase ... 249 6e-66 CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase ... 219 5e-57 CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase ... 215 7e-56 >BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 154 Score = 288 bits (738), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 0/298 (0%), Positives = 0/298 (0%), Gaps = 6/298 (2%) Query: 10 LLQIRDLTKVIGRKTLVDHVSLEMEKGEIMGLLGPNGAGKTTTIRMIVGLVSKSEGQVII 69 + + + + G + ++ + Sbjct: 4 GEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDNIFMNVMTFNTQSPVEKKAE 63 Query: 70 DGIDTGQQFSAAMGKVGVIVEQPDLYKYLSGYDNLILFSRMSPGVTTDRLKEIISLVGLE 129 G+ ++ + + + + S + + + Sbjct: 64 LHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQLCSTIDNEQAIILKPGMFAVF 123 Query: 130 RSISAKVSTYSLGMRQRLGLAVALMHKPSLLLLDEPTNGLDPAGIHELREHLKNLAHKEN 189 Sbjct: 124 183 Query: 190 VGILISSHLMSEMEMMCDRVAVLQQGKLIGVHRL-SELVQEDDALVQFEVDRPELAVQVL 248 Sbjct: 184 - 242 Query: 249 QAVMSGAEITAGHNQLRVRLPKNRIPEISQKLLDSGISVYGVNTVKRTLEDKYLEITG 306 Sbjct: 243 ---- 296 >lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 266 bits (681), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 134/302 (44%), Positives = 199/302 (65%), Gaps = 13/302 (4%) Query: 11 LQIRDLTKVIGRKTLVDHVSLEMEKGEIMGLLGPNGAGKTTTIRMIVGLVSKSEGQVIID 70 LQ+ +L K I ++ ++ +S E+ GE+ G LGPNGAGKTTTIRMIVGL+ + G ++I Sbjct: 6 LQVTNLHKKIRKREIIKGISFEVRPGEVFGFLGPNGAGKTTTIRMIVGLIKPTSGTILIG 65 Query: 71 GIDTGQQFSAAMGKVGVIVEQPDLYKYLSGYDNLILFSRMSPGVTTDRLKEIISLVGLER 130 G D + F+ AM +G IVE P+ Y +L+G +NL F+RM P + +R++E+ LVGLE+ Sbjct: 66 GKDIRKNFTEAMRGLGSIVENPEFYTFLTGQENLAYFARMDPSIKKERIQEVTELVGLEK 125 Query: 131 SISAKVSTYSLGMRQRLGLAVALMHKPSLLLLDEPTNGLDPAGIHELREHLKNLAHKENV 190 I+ +VSTYSLGMRQRLG+A AL+ P LL+LDEPTNGLDP+GIHE+R+ ++ LA E + Sbjct: 126 RINDRVSTYSLGMRQRLGIAQALLSSPKLLILDEPTNGLDPSGIHEMRDFIRALARNEGI 185 Query: 191 GILISSHLMSEMEMMCDRVAVLQQGKLIGVHRLSELVQEDDAL----VQFEVDRPELAVQ 246 +L+SSHL+SE+E++CDRVA++ G +I ++S L+ L FE + LA Sbjct: 186 SVLVSSHLLSEIELLCDRVAIMTDGTIIKTDQVSHLLSSRAQLRWLATPFEQAKAFLA-S 244 Query: 247 VLQAVMSGAEITAGHNQLRVRLPKNRIPEISQKLLDSGISVYGVNTVKRTLEDKYLEITG 306 V + + G + N+ R E +++L+ GI V+ ++ K +LED +LE+TG Sbjct: 245 VTEVEVDGEYLVTAVNE--------RSAEWNEQLVAKGIQVHEIDKKKPSLEDLFLELTG 296 Query: 307 GQ 308 G Sbjct: 297 GH 298 >BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 308 Score = 249 bits (635), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 127/300 (42%), Positives = 192/300 (64%), Gaps = 3/300 (1%) Query: 6 VALPLLQIRDLTKVIGRKTLVDHVSLEMEKGEIMGLLGPNGAGKTTTIRMIVGLVSKSEG 65 +A P+L I L K IG K ++ +S+++ +GEI+GLLGPNG+GKTT IR+IVGL+ ++ G Sbjct: 1 MAEPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSG 60 Query: 66 QVIIDGIDTGQQFSAAMGKVGVIVEQPDLYKYLSGYDNLILFSRMSPGVTTDRLKEIISL 125 V I G +F AM VG IVE P+ Y YL+G++NL F+ M + +RL E++ Sbjct: 61 SVTISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIADERLDEVVER 120 Query: 126 VGLERSISAKVSTYSLGMRQRLGLAVALMHKPSLLLLDEPTNGLDPAGIHELREHLKNLA 185 VGL +I KV TYSLGMRQRLG+A A++H+P LL+LDEPTNGLDPAG+ + R+H+K LA Sbjct: 121 VGLTSAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKELA 180 Query: 186 HKENVGILISSHLMSEMEMMCDRVAVLQQGKLIGVHRLSELVQEDDALVQFEVDRPELAV 245 E +L ++HL+ E+E +CDRV ++Q+G++ L Q + + EV E A+ Sbjct: 181 EMEGTAVLFATHLLREVEDLCDRVIIIQKGEIKAEVSLQGTDQTTEKAI-IEVQPQEKAL 239 Query: 246 QVLQAVMSGAEITAGHNQLRVRLPKNRIPEISQKLLDSGISVYGVNTVKRTLEDKYLEIT 305 L AE G + V + K IPE+++ L+ ++V+ + ++LED++++ T Sbjct: 240 NWLTGNQYQAESQDG--TIVVEVAKENIPELNRSLVGQDLNVFSITPYTQSLEDEFIKAT 297 >CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 312 Score = 219 bits (557), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 109/303 (35%), Positives = 188/303 (62%), Gaps = 7/303 (2%) Query: 10 LLQIRDLTKVIGRKTLVDHVSLEMEKGEIMGLLGPNGAGKTTTIRMIVGLVSKSEGQVII 69 +L+++D+ K IG++ ++ +S +E+G+I G LGPNGAGKTTTIRM+VGL+ + G + I Sbjct: 4 VLEVKDVKKHIGKREIIKGISFSVEEGQIFGFLGPNGAGKTTTIRMLVGLIKPNSGSIKI 63 Query: 70 DGIDTGQQFSAAMGKVGVIVEQPDLYKYLSGYDNLILFSRMSPGVTTDRLKEIISLVGLE 129 G D ++ A+ VG IVE PD+Y +L+G +NLI +++M V+ +R+ E+ ++GL+ Sbjct: 64 MGHDIQKEKEKALSNVGCIVENPDMYGFLTGRENLIQYAKMYGSVSKERIDEVAEIIGLK 123 Query: 130 RSISAKVSTYSLGMRQRLGLAVALMHKPSLLLLDEPTNGLDPAGIHELREHLKNLAHKEN 189 I+ KV YSLGM+QRLGL AL+ +P LL+LDEPTNGLDP GI + R ++ +A + Sbjct: 124 DRINDKVKKYSLGMKQRLGLGQALLVRPKLLILDEPTNGLDPVGIMDFRRIVRLMAEENK 183 Query: 190 VGILISSHLMSEMEMMCDRVAVLQQGKLIGVHRLSEL----VQEDDALVQFEVDRPELAV 245 + ISSH+++E++ +CD VA + G++ V E +E+ + ++ LA+ Sbjct: 184 SAVFISSHILAEIQQVCDTVAFINGGEIKSVESTKESEGKGTKENFGIATSNIN---LAM 240 Query: 246 QVLQAVMSGAEITAGHNQLRVRLPKNRIPEISQKLLDSGISVYGVNTVKRTLEDKYLEIT 305 + L + E+ +++ + P++ +L+ + + V +TLED++++I Sbjct: 241 ETLSKLPFVYEVKNNEDKISAAIQYGTSPKVIAELMKNSVEVIEFYKEHKTLEDRFMQIV 300 Query: 306 GGQ 308 G+ Sbjct: 301 EGE 303 >CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 318 Score = 215 bits (548), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 116/307 (37%), Positives = 184/307 (59%), Gaps = 9/307 (2%) Query: 10 LLQIRDLTKVIGRKTLVDHVSLEMEKGEIMGLLGPNGAGKTTTIRMIVGLVSKSEGQVII 69 +L++ DL K +G K ++ +S +++GEI+G LG NGAGKTTTI+M+VGL++ +G V+I Sbjct: 4 VLEVTDLYKKLGNKEIIKGISFSIKEGEILGFLGRNGAGKTTTIKMLVGLITPDKGSVMI 63 Query: 70 DGIDTGQQFSAAMGKVGVIVEQPDLYKYLSGYDNLILFSRMSPGVTTDRLKEIISLVGLE 129 G D ++ A+ VG +VE P+LY YL+G NL +R +T + +++I + VGL Sbjct: 64 SGHDITKEAEEALSCVGAVVENPELYSYLTGRQNLEQVARFYKDITKEDIEKIGNTVGLS 123 Query: 130 RSISAKVSTYSLGMRQRLGLAVALMHKPSLLLLDEPTNGLDPAGIHELREHLKNLAHKEN 189 + KV YSLGM+QRLGLA AL+ KP LL+LDEPTNGLDP GI E R LK A + Sbjct: 124 GRLDEKVKKYSLGMKQRLGLAEALISKPKLLILDEPTNGLDPTGIIEFRNLLKKQAKENK 183 Query: 190 VGILISSHLMSEMEMMCDRVAVLQQGKLIGVHRLSELVQ-------EDDALVQFEVDRPE 242 + I +SSH++SE+E +CDRVA + G + L + E+ ++ E D+ Sbjct: 184 MAIFVSSHILSEIEQLCDRVAFIDGGIIKSFETLKGTNKDHKTESFENVVIMTKEKDKCT 243 Query: 243 LAVQVLQAVMSG--AEITAGHNQLRVRLPKNRIPEISQKLLDSGISVYGVNTVKRTLEDK 300 A++ + ++ A+ + G + + +P+I+ L + I + + ++ LED+ Sbjct: 244 EALKEISFIIDFKLADESNGIYTFEAKAKLDSVPDITSSLAEKKIRIEQIYKRQQNLEDR 303 Query: 301 YLEITGG 307 Y+E+ G Sbjct: 304 YIELVNG 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,893,618 Number of extensions: 973862 Number of successful extensions: 9217 Number of sequences better than 1.0e-05: 2143 Number of HSP's gapped: 6566 Number of HSP's successfully gapped: 2369 Length of query: 310 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 204 Effective length of database: 26,153,027 Effective search space: 5335217508 Effective search space used: 5335217508 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)