BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0063.p (585 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0290 [T] COG0642 Signal transduction histidine kinase 179 2e-44 L0122 [T] COG0642 Signal transduction histidine kinase 108 3e-23 BS_resE_4 [T] COG0642 Signal transduction histidine kinase 100 6e-21 lin2061 [T] COG0642 Signal transduction histidine kinase 97 1e-19 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 91 7e-18 >CAC0290 [T] COG0642 Signal transduction histidine kinase Length = 467 Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 111/411 (27%), Positives = 205/411 (49%), Gaps = 31/411 (7%) Query: 175 IRARGGYAQLLDPEGRELAALNRPESIPGTYTVQELALRSKYPERYEYRMDFAYDENTGR 234 ++ + + Q++D + E + +P+++P YT E KY E Sbjct: 76 LKDKNAWIQIVDNKLTEAYSYKKPKNVPKQYTPIEFVHVYKYDT---VNSTLFIGEKNKF 132 Query: 235 TWVVGLP--NKAEGHSSKNPLISAEMRIVLIGIAGMLGA---VLLIFALLSFLNALRFGT 289 ++ +G P A+ + NP I+ GI +L A ++LIF + F A + G Sbjct: 133 SYFIGFPIDKIAKYNVEYNP--HNIKTIIGGGILAILAANLIIILIFGYIYF--ARKMGK 188 Query: 290 PMFHMLAWLDSLGRGAYDEPADRNGRPRSRLSSGKWRRRYSTFAEVMLSMDQLTVILRHD 349 P+ +L +++ L G Y G + V +++ L+ +L + Sbjct: 189 PLEKVLIYIEELSNGNYKINEREKG----------------IYKYVFKNLNVLSKVLMDN 232 Query: 350 XXXXXXXXXXXXXWITGITHDLKTPLSSIKGYAHLLAEDAYDWSPEEVRKFSAIMLEKSA 409 WI+ I HD+KTPLSSIKG++ +L ++ YD+ +EVR+++ I+ +KS Sbjct: 233 KNRKKKIDELRDQWISSIGHDMKTPLSSIKGFSEILKDNEYDFEKDEVREYAGIIYDKSL 292 Query: 410 HMDTLISDLAMTYRQRSGIHAPQMEEVEMNAWLGNALIQAAANPEYGEGRIIYQAPDQEI 469 +M+ LI+DL +Y+ R+ + +++ + WL + + + ++PE+ + + ++ + Sbjct: 293 YMEELINDLNFSYKLRNNCVNIKKKKIYFSQWLKDIVYKLHSSPEFKDRNVNIDKINENL 352 Query: 470 TASIYRPWMERVVGNLTANALLHNSSDTRLTVTLS-EGADGGLTIIFRDNGQGMDEQTAA 528 I M+R N+ N L++N D R T+ + + +G + +DNG+G+ E+ Sbjct: 353 IVDIDELMMKRAFVNIITNFLMYN--DNRSTIEVGVKIEEGFIKTTIKDNGKGIPEKDIE 410 Query: 529 NLFERYYRGGDTASTTNGSGLGMAISKGLVEAMGGQITVSSAPGKGTEIRL 579 ++FERYYRG +T S + GSGLGMAI+ +V+ G V S G+GTE+ + Sbjct: 411 HIFERYYRGTNTTSNSKGSGLGMAIANDIVKLHEGFCDVKSKEGEGTELTI 461 >L0122 [T] COG0642 Signal transduction histidine kinase Length = 517 Score = 108 bits (269), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 63/215 (29%), Positives = 119/215 (55%), Gaps = 12/215 (5%) Query: 363 WITGITHDLKTPLSSIKGYAHLLAEDAYDWSPEEVRKFSAIMLEKSAHMDTLISDLAMTY 422 +I ++H+LKTPL+SIKG+A LL D+ S + + F++I+ ++S+ + L+ D + Sbjct: 307 FIANVSHELKTPLTSIKGFAELLETDS--ISSSDTKNFASIINKESSRLMNLVQDTLLLT 364 Query: 423 RQRSGIHAPQMEEVEMNAWLGNALIQAAANPEYGEGRIIYQAPDQEITASIYRPWMERVV 482 +Q H +++ + + N L ++ P+ E + +++ +EIT P + + Sbjct: 365 KQN---HRIDKKKINLTTLIQNIL--QSSGPQINEKSLHFESQIEEITFKTNEPMVHSIF 419 Query: 483 GNLTANALLHNSSDTRLTVTLSEGADGGLTIIFR--DNGQGMDEQTAANLFERYYRGGDT 540 NL NA+ + ++ ++ V+L + +IF DNG G+ E +F+R+YR ++ Sbjct: 420 ENLIENAIKYTPANGQIFVSLHLEQNK---VIFSVTDNGPGLSEIQKERIFDRFYRVDES 476 Query: 541 ASTTNGSGLGMAISKGLVEAMGGQITVSSAPGKGT 575 + +G+GLG+AI + V+ + G I V S GKGT Sbjct: 477 RAEVSGTGLGLAIVEKNVQELHGTIDVVSILGKGT 511 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Length = 269 Score = 100 bits (249), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 70/220 (31%), Positives = 118/220 (53%), Gaps = 15/220 (6%) Query: 363 WITGITHDLKTPLSSIKGYAHLLAEDAYDWSPEEVRKFSAIMLEKSAHMDTLISDLAMTY 422 +I ++H+L+TP+S ++GY+ + +D S E+ ++ + I+ ++S M L++DL Sbjct: 48 FIANVSHELRTPISMLQGYSEAIVDDIAS-SEEDRKEIAQIIYDESLRMGRLVNDLLDLA 106 Query: 423 RQRSGIHAPQMEEVEMNAWLGNALIQAAANPEYGEGRIIYQAPDQEITAS-----IYRPW 477 R SG E++ +N +L + + + G + A D +I+ + Sbjct: 107 RMESGHTGLHYEKINVNEFLEKIIRKFS-----GVAKEKNIALDHDISLTEEEFMFDEDK 161 Query: 478 MERVVGNLTANALLHNSSDTRLTVTLSEGADGGLTIIFRDNGQGMDEQTAANLFERYYRG 537 ME+V NL NAL H S+ +++++ DG L I +D+G G+ E+ +FER+Y+ Sbjct: 162 MEQVFTNLIDNALRHTSAGGSVSISVHSVKDG-LKIDIKDSGSGIPEEDLPFIFERFYKA 220 Query: 538 GDTASTTN--GSGLGMAISKGLVEAMGGQITVSSAPGKGT 575 D A T G+GLG+AI K +VEA G ITV S KGT Sbjct: 221 -DKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGT 259 >lin2061 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 96.7 bits (239), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 0/227 (0%), Positives = 0/227 (0%), Gaps = 13/227 (5%) Query: 363 WITGITHDLKTPLSSIKGYAHLLAEDAYDWSPEEVRKFSAIMLEKSAHMDTLISDLAMTY 422 Sbjct: 369 - 427 Query: 423 RQRSGIHAPQMEEVEMNAWLGNAL--IQAAANPEYGEGRIIYQAPDQEITASIYRP-WME 479 Sbjct: 428 --- 484 Query: 480 RVVGNLTANALLHNSSDTRL-TVTLSEGAD---GGLTIIFRDNGQGMDEQTAANLFERYY 535 Sbjct: 485 544 Query: 536 RGGDTAS--TTNGSGLGMAISKGLVEAMGGQITVSSAPGKGTEIRLS 580 Sbjct: 545 591 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 90.5 bits (223), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 12/235 (5%), Positives = 35/235 (14%), Gaps = 7/235 (2%) Query: 344 VILRHDXXXXXXXXXXXXXWITGITHDLKTPLSSIKGYAHLLAEDAYDWSPEEVRKFSAI 403 ++ TP + LL ++ + Sbjct: 35 LLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQM-QLRNKKRRREL 93 Query: 404 MLEKSAHMDTLISDLAMTYRQRSGIHAPQMEEVEMNAWLGN--ALIQAAANPEYGEGRII 461 S + Sbjct: 94 GNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFT 153 Query: 462 YQAPDQEITASIYRPWMERVVGNLTANALLHNSSDTRLTVTLSEGADGGLTIIFRDNGQG 521 ++ + + + +L + + + L R+ Sbjct: 154 QYLKTRDFSRPLNL--VLNTGRHLEIRVMPYTHKQLLMVARD-VTQMHQLEGARRNFFAN 210 Query: 522 MDEQTAANLFERYYR-GGDTASTTNGSGLGMAISKGLVEAMGGQITVSSAPGKGT 575 + + L G+ A+ + + V Sbjct: 211 VSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSK 265 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,762,170 Number of extensions: 2044905 Number of successful extensions: 7055 Number of sequences better than 1.0e-05: 179 Number of HSP's gapped: 6897 Number of HSP's successfully gapped: 179 Length of query: 585 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 473 Effective length of database: 25,461,023 Effective search space: 12043063879 Effective search space used: 12043063879 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 119 (50.4 bits)