BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0062.p (270 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-li... 171 8e-43 Rv0491 [TK] COG0745 Response regulators consisting of a CheY-lik... 171 1e-42 MT0510 [TK] COG0745 Response regulators consisting of a CheY-lik... 171 1e-42 BH0820 [TK] COG0745 Response regulators consisting of a CheY-lik... 171 1e-42 CAC0321 [TK] COG0745 Response regulators consisting of a CheY-li... 170 2e-42 >Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 171 bits (434), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 95/247 (38%), Positives = 143/247 (57%), Gaps = 21/247 (8%) Query: 12 ILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPGRSGID 71 IL+V+DEES+ + +L KEGF I AG G A++ D+++LD+MLPG SG D Sbjct: 4 ILIVEDEESLADPLAFLLRKEGFDTI-IAGDGPTALVEFSRNEIDIVLLDLMLPGMSGTD 62 Query: 72 ICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLRRYLGM 131 +C LR + PV+ ++AR S+ DK+ G +G DDY+TKP++ EL+ARIR+ LRR Sbjct: 63 VCKELRSVSTVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRR--- 119 Query: 132 VGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVVACPAL 191 G + L P+ + + GR ++D + + V GE V+ P Sbjct: 120 --GVTETEAEEL--------------PLDDQI-LEGGRVRMDVDSHTVTVGGEPVSMPLK 162 Query: 192 VFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANPVFLVN 251 F LL + ++ R+ T+ +L +R+WG D + D T+ VH+ R+R +IE EP+ P +LV Sbjct: 163 EFDLLEYLLRNAGRVLTRGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVT 222 Query: 252 VRGLGYK 258 VRGLGYK Sbjct: 223 VRGLGYK 229 >Rv0491 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/252 (37%), Positives = 145/252 (57%), Gaps = 30/252 (11%) Query: 10 AAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPGRSG 69 ++L+V+DEES+ + +L KEGF + G AA+ D+++LD+MLPG SG Sbjct: 2 TSVLIVEDEESLADPLAFLLRKEGF-EATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 60 Query: 70 IDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLRRYL 129 D+C LR ++ PV+ ++AR S+ DK+ G +G DDY+TKP++ EL+ARIR+ LRR Sbjct: 61 TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR-- 118 Query: 130 GMVGGPEPAQVN--ALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVVA 187 GG + ++++ L P R V+ H+ + V G+ + Sbjct: 119 ---GGDDDSEMSDGVLESGPV-------RMDVERHV---------------VSVNGDTIT 153 Query: 188 CPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANPV 247 P F LL + ++ R+ T+ +L +RVWG D + D T+ VH+ R+R +IE +PANPV Sbjct: 154 LPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPV 213 Query: 248 FLVNVRGLGYKL 259 LV VRGLGYKL Sbjct: 214 HLVTVRGLGYKL 225 >MT0510 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/252 (37%), Positives = 145/252 (57%), Gaps = 30/252 (11%) Query: 10 AAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPGRSG 69 ++L+V+DEES+ + +L KEGF + G AA+ D+++LD+MLPG SG Sbjct: 5 TSVLIVEDEESLADPLAFLLRKEGF-EATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 63 Query: 70 IDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLRRYL 129 D+C LR ++ PV+ ++AR S+ DK+ G +G DDY+TKP++ EL+ARIR+ LRR Sbjct: 64 TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR-- 121 Query: 130 GMVGGPEPAQVN--ALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVVA 187 GG + ++++ L P R V+ H+ + V G+ + Sbjct: 122 ---GGDDDSEMSDGVLESGPV-------RMDVERHV---------------VSVNGDTIT 156 Query: 188 CPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANPV 247 P F LL + ++ R+ T+ +L +RVWG D + D T+ VH+ R+R +IE +PANPV Sbjct: 157 LPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPV 216 Query: 248 FLVNVRGLGYKL 259 LV VRGLGYKL Sbjct: 217 HLVTVRGLGYKL 228 >BH0820 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 234 Score = 171 bits (432), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 94/253 (37%), Positives = 139/253 (54%), Gaps = 23/253 (9%) Query: 7 MNHAAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPG 66 M ILL++D+ SI ++K L EG+ + A GE A + YDL++LD+MLP Sbjct: 1 MIEHKILLIEDDVSISEMVKEHLQLEGY-HVCCAFDGEEATRLFEQNTYDLVLLDLMLPR 59 Query: 67 RSGIDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLR 126 R+GID ++R + PVL +SA+ SD DK G G DDY+TKPF+ +EL AR+++ +R Sbjct: 60 RNGIDCLQWIRTKSVVPVLIMSAKDSDVDKALGLGFGADDYITKPFSMIELTARVKAAIR 119 Query: 127 RYLGMVGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVV 186 R VN S N+R H L + F V + +GE + Sbjct: 120 R-----------TVNYAQASQSAENERIK----IHELVVELSSFTV-------KKKGEEI 157 Query: 187 ACPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANP 246 A FQ+L F HP ++FTK +LY VW +D SD+N + VHI R+RE+IE P+ P Sbjct: 158 KLTAKEFQILKLFVTHPKKVFTKEQLYRSVWNDDYYSDENVINVHIRRLREKIEDTPSKP 217 Query: 247 VFLVNVRGLGYKL 259 ++ + G+GY++ Sbjct: 218 QYIKTIWGIGYRM 230 >CAC0321 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 89/248 (35%), Positives = 145/248 (58%), Gaps = 23/248 (9%) Query: 12 ILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPGRSGID 71 IL+++DE SI L K L F +D +G+ + A + K Y+LI+LD+MLP G + Sbjct: 4 ILIIEDETSIAELEKDYLELSNFK-VDIEVSGKTGLEAAKEKNYELIILDLMLPEIDGFE 62 Query: 72 ICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLRRYLGM 131 IC +R+ N P+L +SA+ D DK+ G +G DDYMTKPF+P ELVAR+++ + RY + Sbjct: 63 ICKQIRKIKNTPILMVSAKKEDIDKIRGLGLGADDYMTKPFSPSELVARVKAHISRYERL 122 Query: 132 VGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVVACPAL 191 VN+ +K + + +G +++A+ ++ V G+ A Sbjct: 123 --------VNSSNKNLDDEIEIRG--------------LNINKASRKVFVNGKESQFTAK 160 Query: 192 VFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANPVFLVN 251 F LL+F ++P+R+F+K EL++++WG D+ + TV VHI +IRE+IE + +NP ++ Sbjct: 161 EFDLLVFLAQNPDRVFSKEELFDKIWGMDSFGEIATVTVHIKKIREKIEKDTSNPEYIET 220 Query: 252 VRGLGYKL 259 V G GY+ Sbjct: 221 VWGAGYRF 228 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.140 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,216,399 Number of extensions: 908302 Number of successful extensions: 2490 Number of sequences better than 1.0e-05: 325 Number of HSP's gapped: 2264 Number of HSP's successfully gapped: 348 Length of query: 270 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 165 Effective length of database: 26,268,361 Effective search space: 4334279565 Effective search space used: 4334279565 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)