BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0599.0061.p
         (341 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SA2004 [M] COG0739 Membrane proteins related to metalloendopepti...   175   9e-44
aq_2113 [M] COG0739 Membrane proteins related to metalloendopept...    60   6e-09
AGc3364 [M] COG0739 Membrane proteins related to metalloendopept...    60   6e-09
TP0864 [M] COG0739 Membrane proteins related to metalloendopepti...    57   5e-08
YPO2062 [M] COG0739 Membrane proteins related to metalloendopept...    56   1e-07

>SA2004 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 284

 Score =  175 bits (444), Expect = 9e-44,   Method: Compositional matrix adjust.
 Identities = 98/265 (36%), Positives = 143/265 (53%), Gaps = 4/265 (1%)

Query: 71  IYKRFSPEFKQQISEAEVAEMGSDFIQGVTAFNPSTVMQLNGSEQRVWTSGAGDKGIIAV 130
           IYK F    K++ S  +  ++   + +           Q + + +++W   A   G+   
Sbjct: 18  IYKIFDQNLKREFSYWQFRKLFKSYTRQSDVHELKVCTQNDDTMEQIWIDKANQFGVAVT 77

Query: 131 FDDSGTILGLSITGLSTYPDSDNALTKTAMALPFQGEWLVFWGGSNVLNNYHYEYASQRY 190
           + D+ +I+G  +  L  Y    N  T    A+P    + VFWGG N L NYHY Y  QRY
Sbjct: 78  WKDN-SIIGFVMRPLINYDAIKNE-TTLKYAVPTTDCYEVFWGGDNELYNYHYLYLHQRY 135

Query: 191 AYDFVQAVNGFSYEGDPLRNESYHAYGQKITAPADGVVTEVVNDIPDNTPVGVMNEKEPA 250
           A D V   N  +Y+     N  Y  +G+ I APA+G V +VVN + DN+ +G  NE +  
Sbjct: 136 AIDLVIKENHKTYKNQGKVNTDYFCFGKDIIAPANGTVEKVVNGVQDNS-IGSTNESQFL 194

Query: 251 GNVVVIDHG-GEYSFLAHLKQGSVTVKKGDAVKAGDVIGKAGNSGNSSEPHLHYQVSDGA 309
           GN +VI H   EYS +AHL+Q S+ V +G  VK GD +GK GNSGNS+EPH+H+QV +  
Sbjct: 195 GNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDFLGKVGNSGNSTEPHIHFQVMNDK 254

Query: 310 DLFTSRSLNIRWKDNLHPLKGQTVA 334
           ++    SL IR+ +NL  +KG  V 
Sbjct: 255 NIEACTSLKIRFLNNLELIKGDVVC 279


>aq_2113 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 139

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 0/54 (0%), Positives = 0/54 (0%), Gaps = 3/54 (5%)

Query: 250 AGNVVVIDHG-GEYSFLAHLKQGSVTVKKGDAVKAGDVIGKAGNSGNSSEPHLH 302
                                                                 
Sbjct: 188 --                                                     239


>AGc3364 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 289

 Score = 59.7 bits (143), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 0/56 (0%), Positives = 0/56 (0%), Gaps = 3/56 (5%)

Query: 251 GNVVVIDHG-GEYSFLAHLKQGSVTVKKGDAVKAGDVIGKAGNSGNSSEPHLHYQV 305
                                                                   
Sbjct: 355 --                                                       408


>TP0864 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 546

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 53/119 (44%), Gaps = 24/119 (20%)

Query: 196 QAVNGFSYEGDPLR-NESYH-------AYGQKITAPADGVVTEVVNDIPDNTPVGVMNEK 247
           +  +GF Y  DP     S+H        YG ++ A  DG V E+                
Sbjct: 428 RRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEI-------------GYS 474

Query: 248 EPAGNVVVIDHGGEY-SFLAHLKQGSVTVKKGDAVKAGDVIGKAGNSGNSSEPHLHYQV 305
              GN ++I HGG Y +   HL   SV V +G  V  G  IG+ G SG ++ PHLH+ V
Sbjct: 475 RIYGNYLIIVHGGGYQTMYGHLS--SVMVGRGARVVQGTTIGRVGASGRATGPHLHFSV 531


>YPO2062 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 417

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/79 (43%), Positives = 45/79 (56%), Gaps = 11/79 (13%)

Query: 235 IPDNTPVGVMNEKE--------PAGNVVVIDHGGEYS-FLAHLKQGSVTVKKGDAVKAGD 285
           +P  TPV  + + E         AGN VVI HG +Y+    HLK+  + VK G  VK GD
Sbjct: 298 MPVGTPVLAVGDGEVLISKFSGAAGNYVVIRHGRQYTTHYMHLKK--LLVKPGQKVKRGD 355

Query: 286 VIGKAGNSGNSSEPHLHYQ 304
            I  +GN+G S+ PHLHY+
Sbjct: 356 RIALSGNTGRSTGPHLHYE 374


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.312    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 26,932,128
Number of extensions: 1123013
Number of successful extensions: 2014
Number of sequences better than 1.0e-05: 31
Number of HSP's gapped: 2022
Number of HSP's successfully gapped: 31
Length of query: 341
Length of database: 38,378,431
Length adjustment: 107
Effective length of query: 234
Effective length of database: 26,037,693
Effective search space: 6092820162
Effective search space used: 6092820162
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 116 (49.3 bits)