BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0048.p (295 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2515 [T] COG0642 Signal transduction histidine kinase 132 5e-31 BH1154_2 [T] COG0642 Signal transduction histidine kinase 128 1e-29 BH0819 [T] COG0642 Signal transduction histidine kinase 124 2e-28 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 107 2e-23 BS_resE_4 [T] COG0642 Signal transduction histidine kinase 102 5e-22 >lin2515 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 132 bits (333), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 0/264 (0%), Positives = 0/264 (0%), Gaps = 12/264 (4%) Query: 19 MTAQLRRYNKGTT-GKKIDVSLFDQRLEALAGEIN----RQSDLVVDAEARRRRTENELR 73 T + Q + + + + Sbjct: 106 ATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHG-IDATPWAFSPWMV- 163 Query: 74 QAIANISHDIRTPLTSIFGYIQLLEAEPITSQEKHEYLT-IVKNRTKRLQALLNDFFELS 132 Sbjct: 164 -- 221 Query: 133 LIESSDYQLKTERIEMNVLLSDILVGFYDRFNERNITPDIRLPQEAVAIYADESAVRRVV 192 Sbjct: 222 281 Query: 193 ENLLINTVKHAAGH--VEICFEHREKTAELRIVNEAKELTDIDVRLLFDRFYTVDRTRSA 250 Sbjct: 282 341 Query: 251 QGSGLGLSIAKSLMDKMNGTLTAE 274 Sbjct: 342 365 >BH1154_2 [T] COG0642 Signal transduction histidine kinase Length = 274 Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 84/249 (33%), Positives = 140/249 (56%), Gaps = 6/249 (2%) Query: 44 LEALAGEINRQSDLVVDAEARRRRTENELRQAIANISHDIRTPLTSIFGYIQLLEAEPIT 103 L LA IN + +E + ++E + I N+SHD+RTPLTSI Y +LL+ Sbjct: 28 LALLAQNINTMKKGMKQSEREQAKSERLKTELITNVSHDLRTPLTSIITYTELLK--DAD 85 Query: 104 SQEKHEYLTIVKNRTKRLQALLNDFFELSLIESSDYQLKTERIEMNVLLSDILVGFYDRF 163 QE+ +Y+ I+ + +RL+ L++D FE S + S + +L E +++ LL L + + Sbjct: 86 EQERADYIEIIDRKARRLKILIDDLFEASKMSSGNIELTLETVDVLQLLQQALAEYGEAL 145 Query: 164 NERNITPDIRLPQEAVAIYADESAVRRVVENLLINTVKHAAGHVEICFEHREK--TAELR 221 + ++ I +P+E + I AD + RV +NL+ N +K++ H + +EK T E+ Sbjct: 146 EQSSLQLRISVPEEPLYIKADGQKIWRVFDNLIQNILKYSLEHTRVYLSVKEKKETVEII 205 Query: 222 IVNEAK-ELTDIDVRLLFDRFYTVDRTRSAQGSGLGLSIAKSLMDKMNGTLTAELHGGNL 280 I N AK EL D +V L +RF D++R+ +GSGLGL+IAKS++D G L ++ G Sbjct: 206 IKNVAKYELGD-NVDELLERFKRGDQSRNTEGSGLGLAIAKSIVDLHEGYLDIDVDGDLF 264 Query: 281 TMTCRWKLT 289 + + +T Sbjct: 265 KVIIQLPMT 273 >BH0819 [T] COG0642 Signal transduction histidine kinase Length = 309 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 138/241 (57%), Gaps = 11/241 (4%) Query: 41 DQRLEALAGEINRQSDLVVD---AEARRRRTENELRQAIANISHDIRTPLTSIFGYIQLL 97 D++L L IN DL+ + A +RTE +R+ +ANISHD++TPLT I GY++ + Sbjct: 55 DEQLRELLRAIN---DLIEEHNQVTATYQRTELSMRKMLANISHDLKTPLTVIHGYVETI 111 Query: 98 EAEPITSQEKHEYLTIVKNRTKRLQALLNDFFELSLIESSDYQLKTERIEMNVLLSDILV 157 A ++ ++ E L V+ +T + L+N FF+L+ +E+ D L +++ +N L + ++ Sbjct: 112 LAGKGSANDR-ERLEKVQTKTIEIIELINKFFDLAKLEAGDQNLTLKKVAVNELCKNRIL 170 Query: 158 GFYDRFNERNITPDIRLPQEAVAIYADESAVRRVVENLLINTVKHA--AGHVEICFEHRE 215 ++D + +I +P + + ADE A+ R+++NL+ N +++ V + H + Sbjct: 171 SYFDLIQNEKLQVEIEIPSQPFYVLADEKALDRILDNLISNAIRYGKDGKMVGLRLYHDD 230 Query: 216 KTAELRIVNEAKELTDIDVRLLFDRFYTVD--RTRSAQGSGLGLSIAKSLMDKMNGTLTA 273 + + + K ++D D +F+R YT++ R + QGSGLGL+I K L +++NG + Sbjct: 231 AYVSIEVWDRGKGISDKDREKVFERLYTLEDSRNKQYQGSGLGLTITKRLTERLNGHIHL 290 Query: 274 E 274 E Sbjct: 291 E 291 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 18/228 (7%), Positives = 43/228 (18%), Gaps = 8/228 (3%) Query: 66 RRTENELRQAIANISHDIRTPLTSIFGYIQLLEAEPITSQEK-HEYLTIVKNRTKRLQAL 124 N LR + TP + LL + + Sbjct: 45 WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGA 104 Query: 125 LNDFFELSLIESSDYQLKTERIEMNVLLSDILVGFYDRFNERNITPDIRLPQEAVAIYAD 184 + + L + +L P+ + Sbjct: 105 ESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRDFSRP 164 Query: 185 ESAVRRVVENLLINTVKHA--AGHVEICFEHREKTAELRIVNEAKELTDIDVRLLFDRFY 242 + V +L I + + + + E N ++ L Sbjct: 165 LNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQG 224 Query: 243 TV--DRTRSAQGSGLGLSIAKSLMDKMNGTL--TAELHGGNL-TMTCR 285 + + +G+ ++ L + Sbjct: 225 YLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTH 272 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Length = 269 Score = 102 bits (255), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 68/214 (31%), Positives = 116/214 (54%), Gaps = 9/214 (4%) Query: 66 RRTENELRQAIANISHDIRTPLTSIFGYIQLLEAEPITSQE-KHEYLTIVKNRTKRLQAL 124 RR + IAN+SH++RTP++ + GY + + + +S+E + E I+ + + R+ L Sbjct: 39 RRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRL 98 Query: 125 LNDFFELSLIESSDYQLKTERIEMNVLLSDILVGFYDRFNERNIT--PDIRLPQEAVAIY 182 +ND +L+ +ES L E+I +N L I+ F E+NI DI L +E Sbjct: 99 VNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMF- 157 Query: 183 ADESAVRRVVENLLINTVKH--AAGHVEICFEHREKTAELRIVNEAKELTDIDVRLLFDR 240 DE + +V NL+ N ++H A G V I + ++ I + + + D+ +F+R Sbjct: 158 -DEDKMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFER 216 Query: 241 FYTVD--RTRSAQGSGLGLSIAKSLMDKMNGTLT 272 FY D RTR G+GLGL+I K++++ NG++T Sbjct: 217 FYKADKARTRGRAGTGLGLAIVKNIVEAHNGSIT 250 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,365,664 Number of extensions: 682710 Number of successful extensions: 9904 Number of sequences better than 1.0e-05: 199 Number of HSP's gapped: 9635 Number of HSP's successfully gapped: 199 Length of query: 295 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 189 Effective length of database: 26,153,027 Effective search space: 4942922103 Effective search space used: 4942922103 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)