BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0041.p (367 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_araR [K] COG1609 Transcriptional regulators 315 6e-86 BH1875 [K] COG1609 Transcriptional regulators 308 1e-83 CAC1340 [K] COG1609 Transcriptional regulators 232 8e-61 TM0275 [K] COG1609 Transcriptional regulators 149 1e-35 CAC2962 [K] COG1609 Transcriptional regulators 127 3e-29 >BS_araR [K] COG1609 Transcriptional regulators Length = 384 Score = 315 bits (808), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 162/359 (45%), Positives = 242/359 (67%), Gaps = 4/359 (1%) Query: 10 KYQVIFDDIKSNILSGAYTVGEQIPTESALQEMYNVSRQTVRKAILELSNEGFLRSEKGS 69 KY + ++I S I G ++IPTE+ L + + VSR T+RKAI +L ++G L S +G Sbjct: 26 KYAQVKEEISSWINQGKILPDQKIPTENELMQQFGVSRHTIRKAIGDLVSQGLLYSVQGG 85 Query: 70 GTYVSHQFRSKSAGSSNNKTIGVITTYISDYIFPSIIRGIEGRLNEDNYSLLLASTNNDV 129 GT+V+ RS + +NKTIGV+TTYISDYIFPSIIRGIE L+E YS+LL STNN+ Sbjct: 86 GTFVAS--RSAKSALHSNKTIGVLTTYISDYIFPSIIRGIESYLSEQGYSMLLTSTNNNP 143 Query: 130 AQEKKALEMMLSFGVEGLIIEPTKSNLYNPNIAYYLSFKEQDVPFIMINAYYEELEVPFF 189 E++ LE +LS ++GLI+EPTKS L PNI YYL+ ++ +PF MINA Y EL P F Sbjct: 144 DNERRGLENLLSQHIDGLIVEPTKSALQTPNIGYYLNLEKNGIPFAMINASYAELAAPSF 203 Query: 190 CLDDVQSSYLATKELISKGHTQIGIIAKMDDLQGKYRMKGYIKALGEAKLRFHPEQVLSF 249 LDDV+ +A + L+S GHT + I K DD QG RM G+I+A E +L P+ +++F Sbjct: 204 TLDDVKGGMMAAEHLLSLGHTHMMGIFKADDTQGVKRMNGFIQAHRERELFPSPDMIVTF 263 Query: 250 DTETKQA-LSANLKNFLSEN-REVLTAIVCYNDEVGLEAVNVCRQLDIAIPEDLSIIGQD 307 TE K++ L +K L +N + + TAI+CYNDE+ L+ +++ R++D+ +PED+SI+G D Sbjct: 264 TTEEKESKLLEKVKATLEKNSKHMPTAILCYNDEIALKVIDMLREMDLKVPEDMSIVGYD 323 Query: 308 NSYIAKNASIKLTTLTHPQEQMGRDAAEWVIKKLQGKKDLRNSTYYQPVLIEGETVKAL 366 +S+ A+ + +KLT++ HP+ +G+ AA++VI L+ KK + ++P LI ++ + L Sbjct: 324 DSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDCLEHKKPKQEDVIFEPELIIRQSARKL 382 >BH1875 [K] COG1609 Transcriptional regulators Length = 375 Score = 308 bits (788), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 159/359 (44%), Positives = 237/359 (66%), Gaps = 2/359 (0%) Query: 7 VKTKYQVIFDDIKSNILSGAYTVGEQIPTESALQEMYNVSRQTVRKAILELSNEGFLRSE 66 ++TKY + IKS IL G +I +E+ L + YNVSR TVRKAI EL NEG++ + Sbjct: 1 METKYNFVKQQIKSKILEGIVLPHGKIGSENELMKEYNVSRHTVRKAIDELVNEGWVYRK 60 Query: 67 KGSGTYVSHQFRSKSA-GSSNNKTIGVITTYISDYIFPSIIRGIEGRLNEDNYSLLLAST 125 +G+GT+ + + K+ G + K I +ITTY+S+YIFPSIIRG E L+E Y + + ST Sbjct: 61 QGAGTFCADRTDQKNPIGKAQRKNIALITTYLSEYIFPSIIRGAESILSEHGYQVTIFST 120 Query: 126 NNDVAQEKKALEMMLSFGVEGLIIEPTKSNLYNPNIAYYLSFKEQDVPFIMINAYYEELE 185 NN+ QEK+ALE +LS +GLI+EPTKS++ NPNI YYL+ + Q +P++MINAYYEELE Sbjct: 121 NNNHEQEKRALEAVLSQRFDGLIVEPTKSSIPNPNINYYLNLERQGIPYVMINAYYEELE 180 Query: 186 VPFFCLDDVQSSYLATKELISKGHTQIGIIAKMDDLQGKYRMKGYIKALGEAKLRFHPEQ 245 F +DDV+ Y TK L+ GH QI + K DDLQG R+KG+IKA E + +P+ Sbjct: 181 PYFLGMDDVKGGYTQTKHLLDLGHEQIVGLFKNDDLQGAKRLKGFIKAHRERGIALNPQH 240 Query: 246 VLSFDTETKQALS-ANLKNFLSENREVLTAIVCYNDEVGLEAVNVCRQLDIAIPEDLSII 304 ++++ TE K A L + T IVCYNDE+ L+ ++V R+ DI +PE+LS++ Sbjct: 241 IITYTTEQKNAKPLEELHRIFKDRSHRPTGIVCYNDELALKLLDVIREFDIRVPEELSVV 300 Query: 305 GQDNSYIAKNASIKLTTLTHPQEQMGRDAAEWVIKKLQGKKDLRNSTYYQPVLIEGETV 363 G D+S+++ + +KLTT+ HP+ +MG DAA+ +I ++ ++ R++ Q ++ E + V Sbjct: 301 GYDDSFLSVASEVKLTTIQHPKVEMGIDAAKLIISCIEQERKDRSADGEQSIIYEPKLV 359 >CAC1340 [K] COG1609 Transcriptional regulators Length = 362 Score = 232 bits (591), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 139/355 (39%), Positives = 214/355 (60%), Gaps = 5/355 (1%) Query: 7 VKTKYQVIFDDIKSNILSGAYTVGEQIPTESALQEMYNVSRQTVRKAILELSNEGFLRSE 66 +K KY+ + + I + G Y E+IPTES L EM++VSR T+RKAI +L ++ Sbjct: 1 MKHKYEEVEEKIIDWAVKGKYKPHEKIPTESELMEMFSVSRHTIRKAIGDLVAMQYVYRI 60 Query: 67 KGSGTYVSHQFRSKSAGSSNNKTIGVITTYISDYIFPSIIRGIEGRLNEDNYSLLLASTN 126 +GSG Y+S ++ N K + V+TT+IS+YIFP II+G+E L ++YSLLL+STN Sbjct: 61 QGSGIYISDWTENREY-LKNTKNVAVLTTHISNYIFPDIIKGMEDTLYSESYSLLLSSTN 119 Query: 127 NDVAQEKKALEMMLSFGVEGLIIEPTKSNLYNPNIAYYLSFKEQDVPFIMINAYYEELEV 186 N+V E L+ +L+ ++GLI+EPTKS +PNI Y + +++P + +NA Y E+ Sbjct: 120 NNVMFENSNLKNLLAHKIDGLILEPTKSAYQSPNIGYLNNIISKNIPVVTLNASYPEINT 179 Query: 187 PFFCLDDVQSSYLATKELISKGHTQIGIIAKMDDLQGKYRMKGYIKALGEAKLRFHPEQV 246 P +DD + LAT LIS GH ++ I K+DD QG RM G+I E + P Q+ Sbjct: 180 PSLKVDDFKGGKLATNHLISLGHRKLMGIFKVDDSQGINRMNGFISECQENNIPPSPGQI 239 Query: 247 LSF-DTETKQALSANLKNFLSENREVLTAIVCYNDEVGLEAVNVCRQLDIAIPEDLSIIG 305 L++ E +L ++ L ++ + + CYNDE+ + + +L+I +PE+LSI+G Sbjct: 240 LTYLSEEISSSLPEKIEYALKSEKKP-SGVFCYNDEIAYIVLTIANKLNIKVPEELSIVG 298 Query: 306 QDNSYIAKNASIKLTTLTHPQEQMGRDAAEWVIKKLQGKKDLR--NSTYYQPVLI 358 D+S +A KLTT+THP+EQMG+DAA+ +I + +S Y+P LI Sbjct: 299 FDDSNLAVIMQPKLTTITHPKEQMGKDAAKLIINLINNSNHFETSDSIVYEPKLI 353 >TM0275 [K] COG1609 Transcriptional regulators Length = 340 Score = 149 bits (375), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 105/353 (29%), Positives = 174/353 (49%), Gaps = 21/353 (5%) Query: 14 IFDDIKSNILSGAYTVGEQIPTESALQEMYNVSRQTVRKAILELSNEGFLRSEKGSGTYV 73 + D+IKS G Y G+++PTE L E +N SR+TVRKA+ L + + + G GT+V Sbjct: 1 MIDEIKS----GKYKHGDKLPTEKELMERFNASRETVRKALERLVVKNLVIRKPGLGTFV 56 Query: 74 SHQFRSKSAGSSNNKTIGVITTYISDYIFPSIIRGIEGRLNEDNYSLLLASTNNDVAQEK 133 + + NK +G++ I+ YIFP I G E L + Y +LL + + D +E+ Sbjct: 57 NIE--------KKNKVVGILVQQITSYIFPYIALGAEEVLFANGYKMLLGNASEDPHKER 108 Query: 134 KALEMMLSFGVEGLIIEPTKSNLYNPNIAYYLSFKEQDVPFIMINAYYEELEVPFFCLDD 193 + + L GV+GLII+P S N ++ ++++ ++ V LDD Sbjct: 109 QIINEWLEVGVDGLIIDPVYSATKRSNRDLIEDMAKKGTKVVLVHTNWDIEGVGSVVLDD 168 Query: 194 VQSSYLATKELISKGHTQIGIIAKMDDLQGKYRMKGYIK---ALGEAKLRFHPEQVLSFD 250 A + GH + ++ K L R + ++K LG K+ V F Sbjct: 169 WYGGEKAAEIFYQYGHRNVAVLYKTIHLPSVVRAQAFLKRGRELGFEKVHEKSFHVSEFT 228 Query: 251 TETKQALSANLKNFLSENREVLTAIVCYNDEVGLEAVNVCRQLDIAIPEDLSIIGQDNSY 310 Q+ + L + + R TA+ CYND L+ +++ + IPED+S+IG D++ Sbjct: 229 GIVMQS-AFELLSLPKDQRP--TAVFCYNDATALQFFLAAKRMGLKIPEDVSVIGFDDAP 285 Query: 311 IAKNASIKLTTLTHPQEQMGRDAAEWVIKKLQGKKDLRNSTYYQPVLIEGETV 363 I I LTT HP+E++G+ A E ++K + G+K ++P LI E+V Sbjct: 286 IGDFREI-LTTFEHPKEEVGKKAVEILLKMIDGEKP--EKYVFKPKLIMRESV 335 >CAC2962 [K] COG1609 Transcriptional regulators Length = 337 Score = 127 bits (318), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 100/358 (27%), Positives = 173/358 (48%), Gaps = 30/358 (8%) Query: 18 IKSNILSGAYTVGEQIPTES-ALQEMYNV---SRQTVRKAILELSNEGFLRSEKGSGTYV 73 +K+ IL A + T S + + Y V +R+ V KAI EL+ Y+ Sbjct: 1 MKTTILEVAKRANVSVATVSRVMNDNYPVKAETREKVLKAIKELN-------------YI 47 Query: 74 SHQFRSKSAGSSNNKTIGVITTYISDYIFPSIIRGIEGRLNEDNYSLLLASTNNDVAQEK 133 + +++ + TIG+++ IS+ F +I GIE L + + SLLL TNNDV +EK Sbjct: 48 PN-MQARELTQKKSATIGIVSPSISNMFFTEVINGIESYLRDKSLSLLLTCTNNDVEEEK 106 Query: 134 KALEMMLSFGVEGLI-IEPTKSNLYNPNIAYYLSFKEQDVPFIMINAYYEELEVPFFCLD 192 K + ++S V G++ I P SN+ N +Y +PF+ IN+ Y + + D Sbjct: 107 KCITNLISRNVSGIVVISPNTSNIKN---GFYDDL-SNSIPFVFINSKYVDSNISSVSND 162 Query: 193 DVQSSYLATKELISKGHTQIGIIAKMDDLQGKYRMKGYIKALGEAKLRFHPEQVLSF--- 249 + ++ A K L+ H +I + D + + Y+ + E L F+P+ +++ Sbjct: 163 ESMGAHNALKYLLKNNHKEILFVRGKDSYSYDIKEEVYVSTMKELNL-FNPQNIINIGNG 221 Query: 250 -DTETKQALSANLKNFLSENREVLTAIVCYNDEVGLEAVNVCRQLDIAIPEDLSIIGQDN 308 +ET S L N+ TA ND +G+ +N C++L++A+P+D SIIG DN Sbjct: 222 NSSETVDNTSYAFLEIL--NKSKATAAFACNDLMGVGILNACKKLNLAVPKDFSIIGYDN 279 Query: 309 SYIAKNASIKLTTLTHPQEQMGRDAAEWVIKKLQGKKDLRNSTYYQPVLIEGETVKAL 366 ++K KLTT+ +G +AA +I+K+ ++E +TV ++ Sbjct: 280 IALSKFVEPKLTTVDQNMFLLGTNAATLLIEKIDCNNKYSKRIILNNYIVERDTVSSI 337 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.132 0.363 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,349,745 Number of extensions: 994676 Number of successful extensions: 2227 Number of sequences better than 1.0e-05: 206 Number of HSP's gapped: 2079 Number of HSP's successfully gapped: 206 Length of query: 367 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 259 Effective length of database: 25,922,359 Effective search space: 6713890981 Effective search space used: 6713890981 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 116 (49.3 bits)