BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0002.p (289 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PAE2839 [C] COG0243 Anaerobic dehydrogenases, typically selenocy... 81 2e-15 mll1128 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, ... 81 2e-15 aq_217 [C] COG0243 Anaerobic dehydrogenases, typically selenocys... 81 2e-15 CAC3396 [L] COG2816 NTP pyrophosphohydrolases containing a Zn-fi... 81 2e-15 ECs2582 [C] COG0243 Anaerobic dehydrogenases, typically selenocy... 81 2e-15 >PAE2839 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 11/140 (7%) Query: 1 MDHNEVIERALIHIEGHLQQSLTVESVANTFNMSKYYFHRLFSAMMSCSLNQYILSRRLN 60 MD +I LI +EGHL Q L++++VA SK++ R+F + ++ YI +RRL+ Sbjct: 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS 60 Query: 61 ASLTFIQNNNRSLTDIAYQLNFGTQASFTRAFKRQYGVAPSSLKTGLTTLSPVPIPAVVK 120 S ++ R + DIA Q F +Q +FTRAFK+Q+ P+ L SP ++ Sbjct: 61 KSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPA-----LYRRSPEWSAFGIR 115 Query: 121 RPIKNINGDIVTDFTLTEFK 140 P++ + +FT+ E K Sbjct: 116 PPLR------LGEFTMPEHK 129 >mll1128 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Length = 289 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 11/140 (7%) Query: 1 MDHNEVIERALIHIEGHLQQSLTVESVANTFNMSKYYFHRLFSAMMSCSLNQYILSRRLN 60 MD +I LI +EGHL Q L++++VA SK++ R+F + ++ YI +RRL+ Sbjct: 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS 60 Query: 61 ASLTFIQNNNRSLTDIAYQLNFGTQASFTRAFKRQYGVAPSSLKTGLTTLSPVPIPAVVK 120 S ++ R + DIA Q F +Q +FTRAFK+Q+ P+ L SP ++ Sbjct: 61 KSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPA-----LYRRSPEWSAFGIR 115 Query: 121 RPIKNINGDIVTDFTLTEFK 140 P++ + +FT+ E K Sbjct: 116 PPLR------LGEFTMPEHK 129 >aq_217 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 11/140 (7%) Query: 1 MDHNEVIERALIHIEGHLQQSLTVESVANTFNMSKYYFHRLFSAMMSCSLNQYILSRRLN 60 MD +I LI +EGHL Q L++++VA SK++ R+F + ++ YI +RRL+ Sbjct: 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS 60 Query: 61 ASLTFIQNNNRSLTDIAYQLNFGTQASFTRAFKRQYGVAPSSLKTGLTTLSPVPIPAVVK 120 S ++ R + DIA Q F +Q +FTRAFK+Q+ P+ L SP ++ Sbjct: 61 KSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPA-----LYRRSPEWSAFGIR 115 Query: 121 RPIKNINGDIVTDFTLTEFK 140 P++ + +FT+ E K Sbjct: 116 PPLR------LGEFTMPEHK 129 >CAC3396 [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding Length = 289 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 11/140 (7%) Query: 1 MDHNEVIERALIHIEGHLQQSLTVESVANTFNMSKYYFHRLFSAMMSCSLNQYILSRRLN 60 MD +I LI +EGHL Q L++++VA SK++ R+F + ++ YI +RRL+ Sbjct: 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS 60 Query: 61 ASLTFIQNNNRSLTDIAYQLNFGTQASFTRAFKRQYGVAPSSLKTGLTTLSPVPIPAVVK 120 S ++ R + DIA Q F +Q +FTRAFK+Q+ P+ L SP ++ Sbjct: 61 KSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPA-----LYRRSPEWSAFGIR 115 Query: 121 RPIKNINGDIVTDFTLTEFK 140 P++ + +FT+ E K Sbjct: 116 PPLR------LGEFTMPEHK 129 >ECs2582 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing Length = 289 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 11/140 (7%) Query: 1 MDHNEVIERALIHIEGHLQQSLTVESVANTFNMSKYYFHRLFSAMMSCSLNQYILSRRLN 60 MD +I LI +EGHL Q L++++VA SK++ R+F + ++ YI +RRL+ Sbjct: 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS 60 Query: 61 ASLTFIQNNNRSLTDIAYQLNFGTQASFTRAFKRQYGVAPSSLKTGLTTLSPVPIPAVVK 120 S ++ R + DIA Q F +Q +FTRAFK+Q+ P+ L SP ++ Sbjct: 61 KSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPA-----LYRRSPEWSAFGIR 115 Query: 121 RPIKNINGDIVTDFTLTEFK 140 P++ + +FT+ E K Sbjct: 116 PPLR------LGEFTMPEHK 129 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.137 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,876,628 Number of extensions: 790267 Number of successful extensions: 2319 Number of sequences better than 1.0e-05: 772 Number of HSP's gapped: 2328 Number of HSP's successfully gapped: 772 Length of query: 289 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 184 Effective length of database: 26,268,361 Effective search space: 4833378424 Effective search space used: 4833378424 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)