BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0598.0004.p (512 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3842 [T] COG4753 Response regulator containing CheY-like recei... 125 2e-28 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 101 3e-21 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 100 8e-21 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 92 2e-18 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 91 5e-18 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 125 bits (313), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 141/545 (25%), Positives = 243/545 (44%), Gaps = 68/545 (12%) Query: 1 MRIVVVEDEATLRRGIIQFIEQMNERYQVVGEADNGADGERIILELQPDLIITDIKMPDM 60 + +++V+DE R G+ F++ +VGEA NG LE QPDL++ DIKMP + Sbjct: 2 INVLIVDDEQIEREGLKLFLKD-RPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGV 60 Query: 61 SGLEMLEKLKAQHFEYRSIILSGYSEFEYAKRAISAGVQEYLLKPFTENE----LRRVLA 116 G++ ++++K Q E I++S + FEYA+ + GV+EYLLKP T+ + L R++ Sbjct: 61 DGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIVG 120 Query: 117 ELSLSIE-------LQRSLDPAHKEGAASFDYYFNSLLLGAPVNLEVLAERLLKEYN--L 167 E+ + E LQ+ L E +SF + L L ++ + + E+N L Sbjct: 121 EIEQAREEKNDQYKLQQRL-----EQISSFVQTESILYL----LMDHIQDYEWMEWNEWL 171 Query: 168 NIRQPFYLAAIYLHENCNE----AEQSW----EKLLYSQLDKTMKGPVCTFALP-----A 214 Q Y H+ E +Q W +K + QL K+ GP LP Sbjct: 172 RTEQEGYAVVFSFHQQGKEIRKTEKQQWHARIKKEIGLQLPKSTVGPFIGHHLPILMLTE 231 Query: 215 DXXXXXXXTDQQSIDQFYRVIKQMLMAEEKPPNMASGFIKCEDMTSFRMQLTELKNDLQW 274 + +Q + Q +KQ + +P + +G + F E Sbjct: 232 NENGMTKQEREQVVIQLLHKVKQAV----QPAKVKTGVGGIYRLHFFSTSYRE------- 280 Query: 275 SIVLGDQIVIDHERI-------QTLVTQIVRYPVELERQIILEIHAIDLNTMYSTCQEFL 327 +L I+ DH++ + + P+E E ++I I + D Q F Sbjct: 281 -ALLALDIIYDHKQASYYFYDKNVKIRADEQLPIERENKLIEAIKSGDGE---KALQAFD 336 Query: 328 HYWRSKLY---HPEDVIHAFVQFCSAIVNA-AHKASLKWEQTLNLRRVYLKLMDSLTWSE 383 HY ++ L HP + ++Q I+ ++ L WE + R + +T Sbjct: 337 HYVQAILRCSKHPLHDMRKYLQQLFIILGRLLNEMGLHWETAQDFAR--FSTVHQVT-EH 393 Query: 384 LSGTLLELYAEMQDSVRDYKLEYSPVIKRVIHYIDLHLHERITQLEVADKLRITPEYLSL 443 +L + +Q+ R + ++ R Y+ H E +T ++A + ++P Y+S Sbjct: 394 GKSEILHIVRTLQE-WRTTDEQSLMLLAR--DYVHDHFREPLTLDDLAKHIGLSPYYVSK 450 Query: 444 LFAKEVGNNFNAYVREKKMNRAKELLIESELSGYEISSLLGFTDPKYFYKVFKNVTGLST 503 LF + F+ YV + ++ AK+LL ++ S EI+ +G+ DP YF +VFK +TG S Sbjct: 451 LFKERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSP 510 Query: 504 SDFIK 508 SD+ K Sbjct: 511 SDYRK 515 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 101 bits (251), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 45/130 (34%), Positives = 86/130 (66%), Gaps = 1/130 (0%) Query: 2 RIVVVEDEATLRRGIIQFIEQMNERYQVVGEADNGADGERIILELQPDLIITDIKMPDMS 61 ++++ +DE +R G+ IE Y+V EADNG D +++ E++PDL+ITDI+MP Sbjct: 3 KVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFD 62 Query: 62 GLEMLEKLKAQ-HFEYRSIILSGYSEFEYAKRAISAGVQEYLLKPFTENELRRVLAELSL 120 GL++++K+ F + II+SGY++F YA++A+ G +++LKP ++EL L +L+ Sbjct: 63 GLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLAA 122 Query: 121 SIELQRSLDP 130 +++ +++ + Sbjct: 123 TLDQEKATNS 132 Score = 60.1 bits (144), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 30/97 (30%), Positives = 54/97 (55%) Query: 410 IKRVIHYIDLHLHERITQLEVADKLRITPEYLSLLFAKEVGNNFNAYVREKKMNRAKELL 469 I +V YI+ H HE I+ +A + P Y+ LF K G F Y+ + +MN AK+LL Sbjct: 423 IYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLL 482 Query: 470 IESELSGYEISSLLGFTDPKYFYKVFKNVTGLSTSDF 506 ++++ YE++ +GF YF F+ + ++ +++ Sbjct: 483 RQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEY 519 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 100 bits (248), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 58/178 (32%), Positives = 99/178 (55%), Gaps = 9/178 (5%) Query: 3 IVVVEDEATLRRGIIQFIEQMNERYQVVGEADNGADGERIILELQPDLIITDIKMPDMSG 62 +++V+DE +R+GII F + E +Q+VGEA NG D +I + +P +++TDI MP M G Sbjct: 4 VLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMDG 63 Query: 63 LEMLEKLKAQHFEYRSIILSGYSEFEYAKRAISAGVQEYLLKP-FTENELRRVLAELSLS 121 +++++++K E I+LS + EFEY + +GV +Y+LKP E +L + L+E+ Sbjct: 64 IDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDLLKTLSEVRGK 123 Query: 122 IELQRSLDPAHKEGAASFDYYFNSLLLG-APVNLEVLAERLLKEYNLNIRQPFYLAAI 178 I +D + S F +L G AP++ + E+ + P+ LA I Sbjct: 124 IPALAKVDSPSR-AVPSISDQFEKILNGHAPLSQDDTGEKRFP------KGPYRLAVI 174 Score = 63.9 bits (154), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 35/105 (33%), Positives = 59/105 (56%) Query: 402 YKLEYSPVIKRVIHYIDLHLHERITQLEVADKLRITPEYLSLLFAKEVGNNFNAYVREKK 461 Y E S I++++ YI+ H E ++ ++A+ P YLS F + F+ Y+ + + Sbjct: 394 YSNEGSSSIQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVR 453 Query: 462 MNRAKELLIESELSGYEISSLLGFTDPKYFYKVFKNVTGLSTSDF 506 + +AKE L S + EI +L+G++D YF KVFK TG+ S + Sbjct: 454 IRKAKEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRY 498 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 92.4 bits (228), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 44/109 (40%), Positives = 70/109 (64%) Query: 3 IVVVEDEATLRRGIIQFIEQMNERYQVVGEADNGADGERIILELQPDLIITDIKMPDMSG 62 +++V+DEA +R G+ I ++V+ A NG +G +L PDL+I DI+MP++ G Sbjct: 4 VMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDG 63 Query: 63 LEMLEKLKAQHFEYRSIILSGYSEFEYAKRAISAGVQEYLLKPFTENEL 111 L ++E ++A+ IILSG+S+F YAK+A+ +YLLKP E+EL Sbjct: 64 LSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDEL 112 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 90.9 bits (224), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 45/122 (36%), Positives = 73/122 (59%) Query: 1 MRIVVVEDEATLRRGIIQFIEQMNERYQVVGEADNGADGERIILELQPDLIITDIKMPDM 60 +R+++V+DE + G+ I+ Y++V A NG + I + DL+ITDIKMP+ Sbjct: 2 IRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPEK 61 Query: 61 SGLEMLEKLKAQHFEYRSIILSGYSEFEYAKRAISAGVQEYLLKPFTENELRRVLAELSL 120 +GLE++ L + RSI+LSG+ EF + K+ ++ G++ YLLKP E EL L+ + Sbjct: 62 TGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVKE 121 Query: 121 SI 122 I Sbjct: 122 KI 123 Score = 78.2 bits (191), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 36/115 (31%), Positives = 67/115 (58%) Query: 397 DSVRDYKLEYSPVIKRVIHYIDLHLHERITQLEVADKLRITPEYLSLLFAKEVGNNFNAY 456 D +++ + YSP+I+ V+ +I H + ++ + I P YL LF +EVG +F Y Sbjct: 392 DHLQENEKNYSPIIQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGCSFTKY 451 Query: 457 VREKKMNRAKELLIESELSGYEISSLLGFTDPKYFYKVFKNVTGLSTSDFIKIHR 511 + + +++RAK+LL+ S +I +G+ D YFYK FK ++ +++ K+H+ Sbjct: 452 LNQLRIDRAKKLLLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRKVHK 506 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,637,419 Number of extensions: 1472708 Number of successful extensions: 4413 Number of sequences better than 1.0e-05: 360 Number of HSP's gapped: 4459 Number of HSP's successfully gapped: 369 Length of query: 512 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 401 Effective length of database: 25,576,357 Effective search space: 10256119157 Effective search space used: 10256119157 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 118 (50.1 bits)