BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0596.0019.p (551 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 157 4e-38 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 106 1e-22 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 97 8e-20 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 95 4e-19 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 89 2e-17 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 157 bits (397), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 134/557 (24%), Positives = 266/557 (47%), Gaps = 58/557 (10%) Query: 2 KILIADDESYMRMSLKTSLNWEAYGFQVIGDAAHGEDALVKIAELKPDIVLMDIKMPIMD 61 K+L+ADDE ++R LK+ + WE G++V +A +GEDA + E+KPD+V+ DI+MP+ D Sbjct: 3 KVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFD 62 Query: 62 GLQALEKL-QGWNDPPKVIMLSSYKEFEYVREGMRLGAVDYIHKPSLNEAGIFDALRRAR 120 GLQ ++K+ + + K I++S Y +F Y ++ +R GAVD++ KP +++ + AL + Sbjct: 63 GLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKP-IDQDELEAALIKLA 121 Query: 121 ETIMRERKQTDEIENLRQNAERVKPNMKAVFFKEWSEGAIRHTWEIEDKMKEYDVRLQAP 180 T+ +E+ N+++ K + +F E + E++++ + +L Sbjct: 122 ATLDQEKA---------TNSDQEKVLLDQIFIHSLGEN------KKENEVRRWAAKLNIN 166 Query: 181 NLVCFAFHIDQFSK-------VRKRYKQDMEYLLYFSIQNILSEVLRKFDEVE----FFQ 229 N + + + + + + ++YK+ I+ ++ E + + E ++ Sbjct: 167 NRHFYYYLLLEVNNLSLDKGFINEQYKE--------PIRKVIRETVARQAATEEYTAIYE 218 Query: 230 HRQNGFAILKSYSSLRSAQSIYNEQWN-LIKTVQNALHKFMNINVSFGISALHLSLLDVP 288 + + +L + L+ +N Q L + ++ + F NI ++ + A L + Sbjct: 219 QLDHAYGLLITSEHLKK----FNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIK 274 Query: 289 LALKEAEKVLESNFYDKESGVIFYQLEGTGSVPGKKEDLNKHAFEKKVQQIKLEIENEQW 348 + + A + + E V + E T SV ++LN H F ++Q +E Sbjct: 275 KSYETANSLRNYKYIFNEKNVFIH--EQTESVDTTYDELNNHLFVTLMEQ----MEENNS 328 Query: 349 ERILGSMGQLFEELRQNRQLSKQEMLRIATYLHYAFS--RACETETGLPIDXXXXXXXXX 406 +RI+ + ++F E + + + + +H +A E +TG I Sbjct: 329 DRIVNIIDKIFSEFQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISAQAMTNWES 388 Query: 407 XXXT----QQQIYELLVQEAEYVQYKKNTNAASQKMNHKIRLVIDYIHEYYDRDLNLEEL 462 T +Q + +++ A +Q + N M I V YI +Y +++L+ + Sbjct: 389 YNLTFDQLKQVFTKFVLEAAVIIQELRKEN-----MKSDIYKVKTYIENHYHENISLKSI 443 Query: 463 SHYVGLNHSYLSRLFKEQTGMVLIQYINQYRVNKSLDLLINSTMKTYEIAERVGFKSTDN 522 + +N Y+ +LFK+ G+ +Y+ + R+N++ LL + M+ YE+AERVGF STD Sbjct: 444 ASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDY 503 Query: 523 FYIAFKRLIGFPPNEVR 539 F F+++ P E R Sbjct: 504 FVTQFEKINKMTPTEYR 520 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 106 bits (264), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 51/121 (42%), Positives = 77/121 (63%) Query: 3 ILIADDESYMRMSLKTSLNWEAYGFQVIGDAAHGEDALVKIAELKPDIVLMDIKMPIMDG 62 +LI DDE +R + +WE GFQ++G+AA+G+DAL I++ +P IV+ DI MP+MDG Sbjct: 4 VLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMDG 63 Query: 63 LQALEKLQGWNDPPKVIMLSSYKEFEYVREGMRLGAVDYIHKPSLNEAGIFDALRRARET 122 + +++++ ++I+LSS++EFEYVR G DYI KP LNE + L R Sbjct: 64 IDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDLLKTLSEVRGK 123 Query: 123 I 123 I Sbjct: 124 I 124 Score = 61.6 bits (148), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/113 (30%), Positives = 61/113 (53%) Query: 428 KKNTNAASQKMNHKIRLVIDYIHEYYDRDLNLEELSHYVGLNHSYLSRLFKEQTGMVLIQ 487 K+ + S + + I+ ++ YI E++ L+L +L++Y N SYLS F++ + Sbjct: 388 KQIISVYSNEGSSSIQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSE 447 Query: 488 YINQYRVNKSLDLLINSTMKTYEIAERVGFKSTDNFYIAFKRLIGFPPNEVRK 540 Y+N+ R+ K+ + L +ST+ EI VG+ F FK+ G PP+ R+ Sbjct: 448 YLNKVRIRKAKEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRR 500 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 96.7 bits (239), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 64/221 (28%), Positives = 113/221 (51%), Gaps = 4/221 (1%) Query: 2 KILIADDESYMRMSLKTSLNWEAYGFQVIGDAAHGEDALVKIAELKPDIVLMDIKMPIMD 61 K++I DDE ++ LK ++W+A G + +G+AA+G L + E P IVL DI MPIM Sbjct: 3 KVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPIMY 62 Query: 62 GLQALEKLQGWNDPPKVIMLSSYKEFEYVREGMRLGAVDYIHKPSLNEAGIFDALRRARE 121 GL ++ L+ +V++LS Y EFE+ R+ M+L DY+ KP+ + I L+R Sbjct: 63 GLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDT-IETVLKRVIN 121 Query: 122 TIMRERKQTDEIENLRQNAERVKPNMKAVFFKEWSEGAIRHTWEIEDKMKEYDVRLQAPN 181 + +++Q ++ L +R +P ++ + K G +R+ EI ++ + + Sbjct: 122 KLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNG-EIPEEFLAKITKWKDQQ 180 Query: 182 LVCFAFHIDQFSKVRKRYKQDMEYLLYFSIQNILSEVLRKF 222 + + D K K YL +S+ ++ EVL + Sbjct: 181 HIACSLTYD--GPQNKELKPADWYLFRYSVHKMIREVLNGY 219 Score = 52.8 bits (125), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 29/129 (22%), Positives = 69/129 (53%), Gaps = 5/129 (3%) Query: 412 QQIYELLVQEAEYVQYKKNTNAASQKMNHK--IRLVIDYIHEYYDRDLNLEELSHYVGLN 469 Q+ L ++ E++ Y + + + + HK I V+ YI ++ ++ L++++ + ++ Sbjct: 397 QEWIRFLCEQIEHICYHQQWD---ENIKHKQLIEQVMIYIEKHLAENITLQDIADELYIS 453 Query: 470 HSYLSRLFKEQTGMVLIQYINQYRVNKSLDLLINSTMKTYEIAERVGFKSTDNFYIAFKR 529 +YL ++FK+ G Y+ + R+ K+ ++ YE++E+VG+ + F FK+ Sbjct: 454 RNYLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKK 513 Query: 530 LIGFPPNEV 538 G+ P ++ Sbjct: 514 YTGYTPRDL 522 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 94.7 bits (234), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 44/136 (32%), Positives = 83/136 (61%), Gaps = 1/136 (0%) Query: 3 ILIADDESYMRMSLKTSLNWEAYGFQVIGDAAHGEDALVKIAELKPDIVLMDIKMPIMDG 62 ++I DDE+ +R LK ++WE YGF+VI A +G++ K +L PD++++DI+MP +DG Sbjct: 4 VMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDG 63 Query: 63 LQALEKLQGWNDPPKVIMLSSYKEFEYVREGMRLGAVDYIHKPSLNEAGIFDALRRARET 122 L +E ++ + I+LS + +F Y ++ + DY+ KP L+E + D+L++ Sbjct: 64 LSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKP-LDEDELIDSLKKVYGR 122 Query: 123 IMRERKQTDEIENLRQ 138 I R + + +E +++ Sbjct: 123 ITRHHQVHELVERVQE 138 Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 1/99 (1%) Query: 442 IRLVIDYIHEYYDRDLNLEELSHYVGLNHSYLSRLFKEQTGMVLIQYINQYRVNKSLDLL 501 +R +I IH+ Y ++L LE L+ N +YL +LFK TG Y+++ R+ LL Sbjct: 399 LRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLL 458 Query: 502 INSTMKTYEIAERVGFKSTDNFYIAFKRLIGFPPNEVRK 540 K YE+AE++G+ + D F+ FK+ +G P+ RK Sbjct: 459 -QKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFRK 496 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 88.6 bits (218), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 50/143 (34%), Positives = 86/143 (60%), Gaps = 2/143 (1%) Query: 1 MKILIADDESYMRMSLKTSLNWEAYGFQVIGDAAHGEDALVKIAELKPDIVLMDIKMPIM 60 + +LI DDE R LK L + ++G+A++G A+ K E +PD+++MDIKMP + Sbjct: 2 INVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGV 60 Query: 61 DGLQALEKLQGWNDPPKVIMLSSYKEFEYVREGMRLGAVDYIHKPSLNEAGIFDALRRAR 120 DG+QA+++++ + IM+S++ FEY RE MR G +Y+ KP+ E + AL R Sbjct: 61 DGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKE-DVLTALDRIV 119 Query: 121 ETIMRERKQTDEIENLRQNAERV 143 I + R++ ++ L+Q E++ Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQI 142 Score = 68.6 bits (166), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 33/98 (33%), Positives = 58/98 (59%) Query: 444 LVIDYIHEYYDRDLNLEELSHYVGLNHSYLSRLFKEQTGMVLIQYINQYRVNKSLDLLIN 503 L DY+H+++ L L++L+ ++GL+ Y+S+LFKE+ + +Y+ Q RV + LL Sbjct: 419 LARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHAKQLLSL 478 Query: 504 STMKTYEIAERVGFKSTDNFYIAFKRLIGFPPNEVRKN 541 + EI +G+K + F FK+L G P++ RK+ Sbjct: 479 TQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYRKS 516 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,252,782 Number of extensions: 1568231 Number of successful extensions: 6008 Number of sequences better than 1.0e-05: 343 Number of HSP's gapped: 6084 Number of HSP's successfully gapped: 354 Length of query: 551 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 440 Effective length of database: 25,576,357 Effective search space: 11253597080 Effective search space used: 11253597080 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)