BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0596.0002.p (357 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1949 [K] COG1609 Transcriptional regulators 194 1e-49 RSc1014 [K] COG1609 Transcriptional regulators 188 1e-47 HI0506 [K] COG1609 Transcriptional regulators 187 2e-47 PM0547 [K] COG1609 Transcriptional regulators 187 2e-47 VC1721 [K] COG1609 Transcriptional regulators 184 2e-46 >PA1949 [K] COG1609 Transcriptional regulators Length = 337 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 112/331 (33%), Positives = 184/331 (55%), Gaps = 9/331 (2%) Query: 31 SIKDVALRANVSTATVSHVINGTRFVSNETKQKVHFAMNELNFRINSVARSLRSRRSYII 90 ++KDVA A VS TVSHV+N TR VS+ ++KV A+ +L++ ++VARSL+ R + II Sbjct: 3 TMKDVAAMAGVSFTTVSHVVNRTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTSII 62 Query: 91 AFLAPILASETSNFYFMSVAAGVQSVLKQRGYHLILSDSSDNVEAENKEISMFDSQMIDG 150 L P ++N YF ++ G++ ++ GY +IL +S DN + + + + + IDG Sbjct: 63 GLLVP----NSTNPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLRVLQEKRIDG 118 Query: 151 LIVAPASRDSDYEQLFGDY--PVVYIDRVPNHCERDSVLIDNKTVTKEATQRILDKGHRK 208 L++A A D + + P V +DR E D V ID++ AT+ +L+ GHR Sbjct: 119 LVLASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRHLLELGHRD 178 Query: 209 IAFLSGPLSVTTTIERYEGYSETLKNAGLELDDSLICFEEVSFENGYNKMGDLL---EKK 265 IA + GPLS + R EGY + AGLE+ + E S GY+ LL ++ Sbjct: 179 IACIGGPLSTKVSTLRVEGYRRAMAKAGLEVRPQWLLESEFSSPGGYHAALGLLGGEGER 238 Query: 266 PTAIFVTDNVMAMGAMTYLQDHSIRIPDQLAVVGFDDVQWTRVTHPPLTVIQQPSFQLGV 325 PTAI ++++ +G + + +IR+P +L+V+GFDD++ +R P LT + Q LG Sbjct: 239 PTAIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIELSRFVFPALTTVGQSIRLLGE 298 Query: 326 KTAEVILQRIEDGTSGKEEHRLKANFLVRQS 356 A+++LQRI + + + ++R+S Sbjct: 299 IAAQLLLQRIAEREEPMQRRVVAPALVLRES 329 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 188 bits (478), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 107/311 (34%), Positives = 175/311 (56%), Gaps = 8/311 (2%) Query: 31 SIKDVALRANVSTATVSHVINGTRFVSNETKQKVHFAMNELNFRINSVARSLRSRRSYII 90 +IKDVA A VS TVSHVIN TR V++ET+++V A+ + ++VARSL+ R + I Sbjct: 3 TIKDVAALAGVSFTTVSHVINNTRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTRTI 62 Query: 91 AFLAPILASETSNFYFMSVAAGVQSVLKQRGYHLILSDSSDNVEAENKEISMFDSQMIDG 150 L P +N YF +A G++ V GY +IL +S D+ + + + + +DG Sbjct: 63 GVLVPT----ATNPYFAELARGIEDVCAAAGYSVILCNSDDDPRKQRDYLRVLMEKRVDG 118 Query: 151 LIVAPASRDSDYEQLFGD--YPVVYIDRVPNHCERDSVLIDNKTVTKEATQRILDKGHRK 208 LIV+ A D+ G+ PVV +DR D V ID++ AT+ +L+ GHR+ Sbjct: 119 LIVSSAGPDNALLDALGESALPVVMVDRPTEGILADQVQIDHEEGAYLATRHLLELGHRR 178 Query: 209 IAFLSGPLSVTTTIERYEGYSETLKNAGLELDDSLICFEEVSFENGYNKMGDLLE--KKP 266 IA +SGP +++ T R G+ L+ AG+ + + + + GY +LL + P Sbjct: 179 IACISGPSTLSVTAGRLAGFHRALREAGVPEHAARVAEGDFTSPGGYRAARELLTTGETP 238 Query: 267 TAIFVTDNVMAMGAMTYLQDHSIRIPDQLAVVGFDDVQWTRVTHPPLTVIQQPSFQLGVK 326 TAIF ++++M +GA+ + I +P +L+++GFDD++ +R +P L+ + Q QLG Sbjct: 239 TAIFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQLGET 298 Query: 327 TAEVILQRIED 337 TA +L+ + D Sbjct: 299 TASTLLEHLTD 309 >HI0506 [K] COG1609 Transcriptional regulators Length = 332 Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 108/332 (32%), Positives = 183/332 (55%), Gaps = 11/332 (3%) Query: 31 SIKDVALRANVSTATVSHVINGTRFVSNETKQKVHFAMNELNFRINSVARSLRSRRSYII 90 ++KD+A A VST+TVSHVING+RFVS+E ++KV + ELN+ ++VARSL+ R + I Sbjct: 3 TMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETKTI 62 Query: 91 AFLAPILASETSNFYFMSVAAGVQSVLKQRGYHLILSDSSDNVEAENKEISMFDSQMIDG 150 +L + T+N +F V AGV+ ++ Y+LI++ + + + + + + +DG Sbjct: 63 G----LLVTATNNPFFAEVMAGVEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDG 118 Query: 151 LIVAPASRDSDYE---QLFGDYPVVYIDRVPNHCERDSVLIDNKTVTKEATQRILDKGHR 207 L++ DS ++ +L P+V +D D +L ++ AT+ ++D GHR Sbjct: 119 LLLMCG--DSRFQADIELAISLPLVVMDWWFTELNADKILENSALGGYLATKALIDAGHR 176 Query: 208 KIAFLSGPLSVTTTIERYEGYSETLKNAGLELDDSLICFEEVSFENGYNKMGDLLEK--K 265 KI ++G L + R +GY L A + L+ I FE G + LL + + Sbjct: 177 KIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSR 236 Query: 266 PTAIFVTDNVMAMGAMTYLQDHSIRIPDQLAVVGFDDVQWTRVTHPPLTVIQQPSFQLGV 325 PTA+F + +A+GA +Q +RIP L+++G+DD++ R PPL+ I QP +LG Sbjct: 237 PTAVFCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGK 296 Query: 326 KTAEVILQRIEDGTSGKEEHRLKANFLVRQSL 357 E +LQRI++ L+ ++R+S+ Sbjct: 297 LAVETLLQRIKNPNENYRTLVLEPTCVLRESI 328 >PM0547 [K] COG1609 Transcriptional regulators Length = 334 Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 105/332 (31%), Positives = 187/332 (56%), Gaps = 9/332 (2%) Query: 31 SIKDVALRANVSTATVSHVINGTRFVSNETKQKVHFAMNELNFRINSVARSLRSRRSYII 90 +IKDVA A VST TVSHVIN TRFV+ ET++ V A+ ELN+ ++VARSL+ + I Sbjct: 3 TIKDVAKMAGVSTTTVSHVINKTRFVAAETEKLVLQAIQELNYSPSAVARSLKVNTTKSI 62 Query: 91 AFLAPILASETSNFYFMSVAAGVQSVLKQRGYHLILSDSSDNVEAENKEISMFDSQMIDG 150 + + +SE YF + V+ ++GY L L ++ +NVE + M + +DG Sbjct: 63 GMI--VTSSEAP--YFAEIIHAVEEHCYRQGYSLFLCNTQNNVEKIKNHLEMLIKKRVDG 118 Query: 151 LIVAPASRDSDYEQLFGDY---PVVYIDRVPNHCERDSVLIDNKTVTKEATQRILDKGHR 207 ++V A D L ++ P+V +D P++ D + + AT+ ++D GH+ Sbjct: 119 ILVMCAEYTQDSLDLLANFTSLPLVVMDWGPDNKHTDIIQDHSFEGGYLATKYLIDHGHK 178 Query: 208 KIAFLSGPLSVTTTIERYEGYSETLKNAGLELDDSLICFEEVSFENGYNKMGDLLEKK-- 265 I ++G L+ TT RYEG+ + + AGL+++ + E+GY M +L + Sbjct: 179 DIGIIAGELTKTTAKTRYEGFIKAMNEAGLKINPDWVMEGFFEPEDGYECMNKILAQDTL 238 Query: 266 PTAIFVTDNVMAMGAMTYLQDHSIRIPDQLAVVGFDDVQWTRVTHPPLTVIQQPSFQLGV 325 PTA+F ++VMA+GA++ + + +R+P+ ++++G+D++ +R PPLT I Q +LG Sbjct: 239 PTAVFCCNDVMALGAISAIGEKGLRVPEDISIIGYDNIHASRFYSPPLTTIHQSKSRLGA 298 Query: 326 KTAEVILQRIEDGTSGKEEHRLKANFLVRQSL 357 + ++ +RI + + + + ++R+S+ Sbjct: 299 RAVTLLFERINEKSEERAVIEMHPELVIRKSV 330 >VC1721 [K] COG1609 Transcriptional regulators Length = 336 Score = 184 bits (466), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 105/314 (33%), Positives = 177/314 (56%), Gaps = 13/314 (4%) Query: 31 SIKDVALRANVSTATVSHVINGTRFVSNETKQKVHFAMNELNFRINSVARSLRSRRSYII 90 +IKDVA A VST TVSHVIN TRFV+ T++KV A+ +LN+ ++VARSL+ + I Sbjct: 3 TIKDVARLAGVSTTTVSHVINKTRFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTRTI 62 Query: 91 AFLAPILASETSNFYFMSVAAGVQSVLKQRGYHLILSDSSDNVEAENKEISMFDSQMIDG 150 +L ++++N +F V GV+S ++GY LIL ++ E + I M + +DG Sbjct: 63 G----MLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDG 118 Query: 151 LIVAPASRDSDYEQLFG---DYPVVYIDRVPNHCERDSVLIDNKTVTKEATQRILDKGHR 207 ++V + + + + D P V +D P D ++ +++ AT+ + D+GH Sbjct: 119 ILVMCSDLTQELQDMLDAHKDIPKVVMDWGPETSHADKIIDNSEEGGYLATKYLTDRGHT 178 Query: 208 KIAFLSGPLSVTTTIERYEGYSETLKNAGLELDDSLICFEEVSFENGYNKMGD----LLE 263 +IA LSG ER +G+ + A L +++ I E +FE + ++ Sbjct: 179 EIACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWIL--EGNFECDTAVLAADKIIAMD 236 Query: 264 KKPTAIFVTDNVMAMGAMTYLQDHSIRIPDQLAVVGFDDVQWTRVTHPPLTVIQQPSFQL 323 K+PTA+F ++ MA+G M+ LQ IRIP+ ++V+G+D+++ PPLT + QP ++ Sbjct: 237 KRPTAVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKRRV 296 Query: 324 GVKTAEVILQRIED 337 G E++L+RI+D Sbjct: 297 GKNAFEILLERIKD 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.133 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,486,753 Number of extensions: 980149 Number of successful extensions: 2308 Number of sequences better than 1.0e-05: 182 Number of HSP's gapped: 1949 Number of HSP's successfully gapped: 182 Length of query: 357 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 249 Effective length of database: 25,922,359 Effective search space: 6454667391 Effective search space used: 6454667391 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)