BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0593.0004.p (320 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all1225 [C] COG0667 Predicted oxidoreductases (related to aryl-a... 155 6e-38 slr0545 [C] COG0667 Predicted oxidoreductases (related to aryl-a... 137 2e-32 DR2261 [C] COG0667 Predicted oxidoreductases (related to aryl-al... 127 2e-29 BS_iolS [C] COG0667 Predicted oxidoreductases (related to aryl-a... 124 2e-28 lin2113 [C] COG0667 Predicted oxidoreductases (related to aryl-a... 120 2e-27 >all1225 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Length = 346 Score = 155 bits (393), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 19/282 (6%), Positives = 42/282 (14%), Gaps = 12/282 (4%) Query: 36 FGNNLTVEDLKPVFDSAMKAGLNLWDTATVYGMGASESILGEFTK-GRDDVLLSTKFTPQ 94 + + + A + + K G + L+ Sbjct: 31 DAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSG 90 Query: 95 ----LGGPVEDRLNSSLNRLGTDHTDIYWIHNP----LDVKRWTPELIPLIKSGKVKYAG 146 + + D L W + Sbjct: 91 PSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTD 150 Query: 147 VSNHNLEEIKLAQSILAEEGLKISAVQNHYSLLYRSSEEAGVIDYCNENNIVFFSYMVLE 206 + L + KI + + + D + IV Sbjct: 151 SAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSL 210 Query: 207 QGALTDKYNV-KNPLPSGTRRGEA-FNEDVLAKLEGLIHVMKEIGDKHNATSAQVAITWA 264 + + + L + + + + Sbjct: 211 LNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQT 270 Query: 265 IAKGTV-PIIGVTRTSHIADAVKAAEIMLTAKDIRDLEAAAK 305 I A A L A Sbjct: 271 QKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTM 312 >slr0545 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Length = 314 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 91/283 (32%), Positives = 152/283 (53%), Gaps = 12/283 (4%) Query: 35 VFGNNLTVEDLKPVFDSAMKAGLNLWDTATVYGMGASESILGEFTKGR-DDVLLSTKFTP 93 +G + ++++ F ++++AG+ L DTA +YG G SE ++G F + + V ++TK+ P Sbjct: 30 AYGKDFGPQEVEGAFHASLEAGVTLIDTAEIYGFGESERLIGRFCREKTQKVEIATKYFP 89 Query: 94 ----QLGGPVEDRLNSSLNRLGTDHTDIYWIHNPLDVKRWTPELIPL----IKSGKVKYA 145 + L +SL RL D +Y IH PL+ TP+ + + +K G+++ Sbjct: 90 LPWRWQRSDITKALTASLERLQMDTICLYQIHWPLEFWLKTPDFMAVLAAEVKKGRIQAV 149 Query: 146 GVSNHNLEEIKLAQSILAEEGLKISAVQNHYSLLYRSSEEAGVIDYCNENNIVFFSYMVL 205 GVSN++ +++ +A LA +G+ +++ Q YSLL R E G++ + N+ +Y L Sbjct: 150 GVSNYSAQQMAIAHECLAAQGIPLASNQVPYSLLNREIESNGILTQARQLNVTILAYSPL 209 Query: 206 EQGALTDKYNVKN-PLPSGTRRGEA-FNEDVLAKLEGLIHVMKEIGDKHNATSAQVAITW 263 QG LT KY +N P G RR + F+ L KL L+ ++ + DKH+ T AQ+A+ W Sbjct: 210 AQGLLTGKYRPENSPSLQGARRLDPRFSTKGLRKLAPLLTLLDTLADKHDKTPAQIALNW 269 Query: 264 AIAKGTV-PIIGVTRTSHIADAVKAAEIMLTAKDIRDLEAAAK 305 IA+G V PI G S A L ++I L +AA+ Sbjct: 270 LIAQGNVIPIPGAKNASQAQQNAGALGWQLNPEEIEQLRSAAQ 312 >DR2261 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Length = 346 Score = 127 bits (320), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 16/291 (5%), Positives = 37/291 (12%), Gaps = 33/291 (11%) Query: 36 FGNNLTVEDLKPVFDSAMKAGLNLWDTATVYGMGASESILGEFTKG-RDDVLLSTKF--- 91 + + + Sbjct: 28 SEADAHAQLDY-AVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIAS 86 Query: 92 ----TPQLGG----P--VEDRLNSSLNRLGTDHTDIYWIHNPLDVKRWTP------ELIP 135 + P DR N + + + + Sbjct: 87 KVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD---LYQVHWPQRPTNCFGK 143 Query: 136 LIKSGKVKYAGVSNHNLEEIKLAQSILAEEGLKISAVQNHYSLLYRSSEEAGVIDYCNEN 195 L S VS + + + + ++ Sbjct: 144 LGYSWTDSAPAVSLLDTLDALAEYQRAG-----KIRYIGVSNETAFGVMRYLHLADKHDL 198 Query: 196 NIVFFSYMVLEQGALTDKYNVKNPL-PSGTRR-GEAFNEDVLAKLEGLIHVMKEIGDKHN 253 + + + + G + + L Sbjct: 199 PRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTL 258 Query: 254 ATSAQVAITWAIAKGT--VPIIGVTRTSHIADAVKAAEIMLTAKDIRDLEA 302 + K I A A L A Sbjct: 259 FSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGA 309 >BS_iolS [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Length = 346 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 15/286 (5%), Positives = 42/286 (14%), Gaps = 41/286 (14%) Query: 39 NLTVEDLKPVFDSAMKAGLNLWDTATVYGMGASESILGEFTK--GRDDVLLSTKFTPQLG 96 + + V + + + G Sbjct: 31 DAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSG 90 Query: 97 GP----------VEDRLNSSLNRLGTDHTDIYWIHNPLDVKRWTPE------LIPLIKSG 140 + L + + + Sbjct: 91 PSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD---LYQVHWPQRPTNCFGKLGYS 147 Query: 141 KVKYAGVSNHNLEEIKLAQSILAEEGLKISAVQNHYSLLYRSSEEAGVIDYCNENNIVFF 200 A + LA+ + S + +++++ Sbjct: 148 WTDSAPAVSLLDTLDALAE----YQRA-GKIRYIGVSNETAFGVMR-YLHLADKHDLPRI 201 Query: 201 SYMVLEQGALTDKYNVKNPLPSGTRR-------GEAFNEDVLAKLEGLIHVMKEIGDKHN 253 + L + V S F + N Sbjct: 202 VTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGK-----YLNGAKPAGARN 256 Query: 254 ATSAQVAITWAIAKGTVPII--GVTRTSHIADAVKAAEIMLTAKDI 297 ++ + R + A A + + Sbjct: 257 TLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFV 302 >lin2113 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Length = 346 Score = 120 bits (302), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 16/282 (5%), Positives = 37/282 (13%), Gaps = 33/282 (11%) Query: 46 KPVFDSAMKAGLNLWDTATVYGMGASESILGEFTK---GRDDVLLSTKF-------TPQL 95 + A + + K ++ S Sbjct: 41 AQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIR 100 Query: 96 GG----PVEDRLNSSLNRLGTDHTDIYWIHN---PLDVKRWTPELIPLIKSGKVKYAGVS 148 R + + + S + Sbjct: 101 PDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT 160 Query: 149 NHNLEEIKLAQSILAEEG-LKISAVQNHYSLLYRSSEEAGVIDYCNENNIVFFSYMVLEQ 207 L E + A I + + Y L + I + + Sbjct: 161 LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLAD-KHDLPRIVTIQNPYSLLNRSFEVGL 219 Query: 208 GALTDKY------NVKNPLPSGTRRGEAFNEDVLAKLEGLIHVMKEIGDKHNATSAQVAI 261 ++ + T + + Sbjct: 220 AEVSQYEGVELLAYSCLGFGTLTGKY-LNGAK-----PAGARNTLFSRFTRYSGEQTQKA 273 Query: 262 TWAIAKG--TVPIIGVTRTSHIADAVKAAEIMLTAKDIRDLE 301 A + L D Sbjct: 274 VAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQL 315 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.133 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,910,170 Number of extensions: 908235 Number of successful extensions: 33344 Number of sequences better than 1.0e-05: 6306 Number of HSP's gapped: 26894 Number of HSP's successfully gapped: 6308 Length of query: 320 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 214 Effective length of database: 26,153,027 Effective search space: 5596747778 Effective search space used: 5596747778 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)