BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0591.0028.p (277 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1627 [K] COG2186 Transcriptional regulators 97 3e-20 BMEI1373 [K] COG2186 Transcriptional regulators 81 2e-15 BH1835 [K] COG2186 Transcriptional regulators 65 1e-10 CAC2546 [K] COG2186 Transcriptional regulators 59 1e-08 AGl2076 [K] COG2186 Transcriptional regulators 58 2e-08 >PA1627 [K] COG2186 Transcriptional regulators Length = 215 Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 59/200 (29%), Positives = 95/200 (47%), Gaps = 1/200 (0%) Query: 47 RRKLVDEVLDQLMGLIQSGQYXXXXXXXXXXXXXXXXSVGRSTVREAVKILVHAGFLEVR 106 +R LVD L+Q+ I +G + + R+TVREAV++L +G LEVR Sbjct: 6 KRSLVDIALEQIRQRIDAGHWPLGQRLPPEPELAELLGMSRNTVREAVRVLTFSGVLEVR 65 Query: 107 QGDGTYVKMPSIGFQSVQATLIPQNFEQVLEVRRMLEIEXXXXXXXXXXXXXIGIMRSRL 166 QGDGTYV+ + +++ L + LE R M+EIE + +R L Sbjct: 66 QGDGTYVRACADPLETM-LVLARSAVQHSLEARGMIEIEAARLAAVRRDDSDLSALREHL 124 Query: 167 DLRNEYLDKGRYAEYVAADISFHMAVVEACHNDVFSAMYKVIADGLREMLSQLILDTRGY 226 D + +Y+ D+ FH +V+A HN V S +Y+ + +R L + + D + Sbjct: 125 DASRQRYGSADLQDYIEHDVRFHQRMVDAAHNPVLSELYRYFSQVIRTSLERTMADPQRA 184 Query: 227 EDNTIYHEAIYMAIKAGDSD 246 + H+ + AI+ GD D Sbjct: 185 QPCFELHQQLLDAIERGDPD 204 >BMEI1373 [K] COG2186 Transcriptional regulators Length = 225 Score = 80.9 bits (198), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 89/210 (42%), Gaps = 9/210 (4%) Query: 42 LKAVQRRKLVDEVLDQLMGLIQSGQYXXXXXXXXXXXXXXXXSVGRSTVREAVKILVHAG 101 +K + R L + + + I SG++ R TVREAV+ LV G Sbjct: 1 MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQG 60 Query: 102 FLEVRQGDGTYVKMPSIGFQS---VQATLIPQNFEQVLEVRRMLEIEXXXXXXXXXXXXX 158 LE RQG GTYV+ + +S ++ T + F E R +LE E Sbjct: 61 MLETRQGSGTYVRSAADTARSLDRIRHTSLRDRF----ETRALLETEAARLAAQRATPKI 116 Query: 159 IGIMRSRLDLRNEYLDKGRYAEYVAADISFHMAVVEACHNDVFSAMYKVIADGLREMLSQ 218 I + LD R D R A +VA D +FH A+V A N + +Y + +RE + + Sbjct: 117 IARLNKLLDERTGRADMDR-ATFVARDFAFHEAIVAASGNSALAEIYAFFSASIRESI-E 174 Query: 219 LILDTRGYEDNTIYHEAIYMAIKAGDSDGA 248 LD E + H I AI GD D A Sbjct: 175 ATLDGGLPEPSDEAHRRIVEAIATGDPDKA 204 >BH1835 [K] COG2186 Transcriptional regulators Length = 216 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 19/185 (10%) Query: 84 SVGRSTVREAVKILVHAGFLEVRQGDGTYVKMPSIGFQSVQATLIPQ------NFEQVLE 137 +V RS VREA+ L G++ ++QG+GTYV + A + P+ E++L+ Sbjct: 24 NVSRSAVREALSALRAIGYITIKQGEGTYVN--KFDVSQMMAPVSPERIMSKKEIEELLQ 81 Query: 138 VRRMLEIEXXXXXXXXXXXXXIGIMRSRL-DLRNEYLDKGRYAEYVAADISFHMAVVEAC 196 +R+++E+ + MR+ L D+ D G AD+ FH+A+ +A Sbjct: 82 IRKIMEVGAASLAATHRTDEDLAEMRAALTDMAQSEGDLGE-----KADVRFHLALAKAT 136 Query: 197 HNDVFSAMYKVIADGLREMLSQ-----LILDTRGYEDNTIYHEAIYMAIKAGDSDGAKRY 251 +N + M + ++D L + + + L + E HE IY AI+A D++GA Sbjct: 137 NNGMLHDMMQQLSDTLGKTMYETRRIALFSTKQTLERLQDEHERIYEAIEARDAEGANDA 196 Query: 252 TAQNL 256 Q+L Sbjct: 197 MLQHL 201 >CAC2546 [K] COG2186 Transcriptional regulators Length = 231 Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 55/235 (23%), Positives = 101/235 (42%), Gaps = 39/235 (16%) Query: 45 VQRRKLVDEVLDQLMGLIQSGQYXXXXXXXXXXXXXXXXSVGRSTVREAVKILVHAGFLE 104 V+ K+ +++++Q +I +G V R+++REA+ L GF+E Sbjct: 5 VKSTKVYEQIIEQFKIMIANGTLKKGDKLPSERELVSQLGVSRASIREALSALQMIGFVE 64 Query: 105 VRQGDGTYVKMPSIGFQSVQATLI-P---------QNFEQVLEVRRMLEIEXXXXXXXXX 154 R G+G +++ ++ + +LI P N EQ+LE+RR++E+E Sbjct: 65 ARHGEGNFIR------ENFEESLIDPFLLIFMLNGSNKEQILELRRIIEVETAALAAKKI 118 Query: 155 XXXXIG----IMRSRLDLRNEYLDKGRYAEYVAADISFHMAVVEACHNDVFSAMYKVIAD 210 + + + + NE L KG+Y D FH + +A N + M ++ Sbjct: 119 TDEEVKELEVCLENLTEAENETL-KGKY------DKKFHYNIAKASKNILIVNMLNAVSS 171 Query: 211 GLREMLSQLILDTRG----YEDNT----IYHEAIYMAIKAGDSDGAKRYTAQNLD 257 ++ I + RG EDN H ++ A+K DS A +++LD Sbjct: 172 ----LMDSFISEARGRILMVEDNKNVLMKQHRSMLEALKNHDSKAASNAMSEHLD 222 >AGl2076 [K] COG2186 Transcriptional regulators Length = 72 Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 0/183 (0%), Positives = 0/183 (0%), Gaps = 18/183 (9%) Query: 40 TGLKAVQRRKLVDEVLDQLMGLIQSGQYXXXXXXXXXXXXXXXXSVGRSTVREAVKILVH 99 Sbjct: 15 74 Query: 100 AGFLEVRQGDGTYVKMPS----IGFQSVQATLIPQNFEQVLEVRRMLEIEXXXXXXXXXX 155 Sbjct: 75 ------- 127 Query: 156 XXXIGIMRSRLDLRNEYLDKGRYAEYVAADISFHMAVVEACHNDVFSAMYKVIADGLREM 215 Sbjct: 128 ------- 180 Query: 216 LSQ 218 Sbjct: 181 183 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,945,841 Number of extensions: 626727 Number of successful extensions: 1178 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 1213 Number of HSP's successfully gapped: 21 Length of query: 277 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 172 Effective length of database: 26,268,361 Effective search space: 4518158092 Effective search space used: 4518158092 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)