BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0591.0005.p (186 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0513 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 189 3e-48 all1011 [R] COG0110 Acetyltransferase (isoleucine patch superfam... 166 2e-41 PM1056 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 165 4e-41 SA2342 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 160 7e-40 ZlacA [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 160 1e-39 >MA0513 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 199 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 91/187 (48%), Positives = 121/187 (64%), Gaps = 1/187 (0%) Query: 1 VSEMSEKEKSHTGLLYQPN-DPELVADRDVTVKKLYDYNNLHPLERELRSAAIRELLGKV 59 + EM+EKEK+ GLLY + D EL+ +R Y+YN LHP + R+A I++L GK Sbjct: 6 MDEMTEKEKAARGLLYNASYDKELIDERAYCKALCYEYNQLHPAKIVERTALIQKLFGKT 65 Query: 60 GENCVVEQQLFCTYGYNTTLGNNCFINLNCKLMDSGFITIGDNVFIAPNVCIITENHAMD 119 G + ++E C YGYN +G+N + N NC ++D + GDNV IAPN T H +D Sbjct: 66 GGSFLIEPPFICDYGYNIEIGSNFYANHNCIILDEAKVVFGDNVMIAPNCGFYTAGHPLD 125 Query: 120 VEHRLAGLEYTAPVTIGDNVWIGAGVIILPGVTIGANSVIGAGSVVTKDIPPSTLAVGNP 179 E R AGLEY P+ +G NVWIG V++LPG+TIG ++VIGAGSVVTKDIP +A GNP Sbjct: 126 AERRNAGLEYAYPIKVGGNVWIGGNVVVLPGITIGDSTVIGAGSVVTKDIPSGVVAAGNP 185 Query: 180 CTAIRSL 186 C IR + Sbjct: 186 CRVIREI 192 >all1011 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 192 Score = 166 bits (420), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 86/184 (46%), Positives = 112/184 (60%) Query: 3 EMSEKEKSHTGLLYQPNDPELVADRDVTVKKLYDYNNLHPLERELRSAAIRELLGKVGEN 62 E +EK+K G LY +DPEL A+ + L YN + E R ++EL +VGE Sbjct: 8 EKTEKQKMLAGELYLADDPELAAESKRASRLLRMYNATTEEQPEQRRQILQELFAQVGEK 67 Query: 63 CVVEQQLFCTYGYNTTLGNNCFINLNCKLMDSGFITIGDNVFIAPNVCIITENHAMDVEH 122 + L C YG N GN ++N C ++D + IG+NV +AP+V I T H + E Sbjct: 68 ITIVPPLHCDYGSNIYAGNGVYMNYGCVILDCNKVEIGENVLLAPHVQIYTAYHPTEPEI 127 Query: 123 RLAGLEYTAPVTIGDNVWIGAGVIILPGVTIGANSVIGAGSVVTKDIPPSTLAVGNPCTA 182 RL+G E AP+ IG+NVWIG G II PGVTIG N+ IGAGSVV KDIP + +AVGNPC Sbjct: 128 RLSGRELAAPIKIGNNVWIGGGAIICPGVTIGDNTTIGAGSVVVKDIPTNVVAVGNPCRI 187 Query: 183 IRSL 186 IR+L Sbjct: 188 IRNL 191 >PM1056 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 203 Score = 165 bits (417), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 84/184 (45%), Positives = 115/184 (62%), Gaps = 1/184 (0%) Query: 4 MSEKEKSHTGLLYQPNDPELVADRDVTVKKLYDYNNL-HPLERELRSAAIRELLGKVGEN 62 +++KEK H GL +QP DPEL R + L++YN L P +++ ++ I +LGK Sbjct: 2 LTDKEKRHLGLAHQPYDPELAEMRLRNKELLHEYNVLTRPSDKQTKARLILSILGKAANT 61 Query: 63 CVVEQQLFCTYGYNTTLGNNCFINLNCKLMDSGFITIGDNVFIAPNVCIITENHAMDVEH 122 + +C YG +G N F N +C ++D+G + IGD+V APNV + T H +D E Sbjct: 62 PHINTPFYCDYGQFIEVGKNFFANYHCTILDTGGVKIGDDVLFAPNVSLYTVGHPIDPEL 121 Query: 123 RLAGLEYTAPVTIGDNVWIGAGVIILPGVTIGANSVIGAGSVVTKDIPPSTLAVGNPCTA 182 R A E P+ IG+NVWIG V+IL GVTIG N+VIGAGSVVTKDIP + +AVGNPC Sbjct: 122 RKAEWEQALPIVIGNNVWIGGNVVILGGVTIGDNTVIGAGSVVTKDIPANCVAVGNPCKV 181 Query: 183 IRSL 186 R + Sbjct: 182 QRMI 185 >SA2342 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 199 Score = 160 bits (406), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 82/184 (44%), Positives = 103/184 (55%), Gaps = 1/184 (0%) Query: 4 MSEKEKSHTGLLYQPN-DPELVADRDVTVKKLYDYNNLHPLERELRSAAIRELLGKVGEN 62 M+EKEK Y N D +L+ +R ++ N+ P + R I +L +N Sbjct: 1 MTEKEKMLAEKWYDANFDQDLINERARAKDICFELNHTKPSDTNKRKELIDQLFQTTTDN 60 Query: 63 CVVEQQLFCTYGYNTTLGNNCFINLNCKLMDSGFITIGDNVFIAPNVCIITENHAMDVEH 122 + YG+N LG N ++N NC MD G ITIGDNVFI PN T H ++ H Sbjct: 61 VSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFYH 120 Query: 123 RLAGLEYTAPVTIGDNVWIGAGVIILPGVTIGANSVIGAGSVVTKDIPPSTLAVGNPCTA 182 R G E P+ IG N W G V +LPGVTIG SVIGAGSVVTKDIPP +LAVGNPC Sbjct: 121 RNEGYEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKV 180 Query: 183 IRSL 186 +R + Sbjct: 181 VRKI 184 >ZlacA [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 203 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 76/153 (49%), Positives = 103/153 (67%) Query: 34 LYDYNNLHPLERELRSAAIRELLGKVGENCVVEQQLFCTYGYNTTLGNNCFINLNCKLMD 93 +Y++N+ HP E + R + I+E+ VGEN VE ++ +YG N +G N + N N ++D Sbjct: 33 MYEFNHSHPSEVDKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVD 92 Query: 94 SGFITIGDNVFIAPNVCIITENHAMDVEHRLAGLEYTAPVTIGDNVWIGAGVIILPGVTI 153 +TIGDNV IAPNV + H + E R G Y+ P+TIG+NVWIG+ V+I PGVTI Sbjct: 93 DYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTI 152 Query: 154 GANSVIGAGSVVTKDIPPSTLAVGNPCTAIRSL 186 G NSVIGAGS+VTKDIPP+ +A G PC IR + Sbjct: 153 GDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREI 185 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,359,747 Number of extensions: 597733 Number of successful extensions: 1650 Number of sequences better than 1.0e-05: 107 Number of HSP's gapped: 1502 Number of HSP's successfully gapped: 107 Length of query: 186 Length of database: 38,378,431 Length adjustment: 100 Effective length of query: 86 Effective length of database: 26,845,031 Effective search space: 2308672666 Effective search space used: 2308672666 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 112 (47.8 bits)