BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0584.0068.p (531 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1893 [T] COG2199 FOG: GGDEF domain 245 1e-64 aq_035_2 [T] COG2199 FOG: GGDEF domain 124 3e-28 AGc2387 [T] COG3706 Response regulator containing a CheY-like re... 122 1e-27 ECs1925_3 [T] COG2199 FOG: GGDEF domain 121 3e-27 Z2421_3 [T] COG2199 FOG: GGDEF domain 121 3e-27 >RSc1893 [T] COG2199 FOG: GGDEF domain Length = 533 Score = 245 bits (626), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 154/492 (31%), Positives = 243/492 (49%), Gaps = 9/492 (1%) Query: 39 ASYHSKKKSLIETTLNLNLANAERMSRTMDSLFRSMRSSMEYSADKLSKLHELSPGQVND 98 +SY +++ LI L N A +++ + D R + Y A L+ H P ++ + Sbjct: 25 SSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVTRQELAYGAGLLAA-HMEDPARLTE 83 Query: 99 YLELMRKSSTYFNSILLVGADGIVRNTSPATLGMEGKPVMSPWAVEALRLKKPYLSEPYT 158 E +R+ NS+++V DG V SPA+L + K + S W L + P +S P+ Sbjct: 84 EAERLRQQMGSLNSVVIVRRDGAVIGASPASLQL--KSMRSDWGRRLLDSRIPEISRPFR 141 Query: 159 ALSTGRMIVFMSEPVYDPDKHYLGQLGGTIYLQDNNILNMIFGNTNDIDAXXXXXXXXXX 218 A TGR+++F+S PV D LG +GGTIYL + N+L+ IF + D Sbjct: 142 A-PTGRLLIFLSHPVIDGQGRLLGYVGGTIYLNEKNLLHTIFVHHYYRDGSYIYVVDRDG 200 Query: 219 XXHLLFHPDKERINEDVSSSEVVQELMKGNSGQREAFNIRGVRMLAGYSSVQANGWGIVA 278 +++HP+ + + ++ V E+M G++G + ++ G+ MLAGY+ V + GWGIVA Sbjct: 201 T--VIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGIDMLAGYAPVASTGWGIVA 258 Query: 279 VSPVSFIQEELWSQLRITLAYTXXXXXXXXXXXXXXXXXXXXPFVMLADLMSRVGKGKAE 338 P +L + +TL+++ P V LA +R+ Sbjct: 259 QKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISRPLVELAS-QARLVATPER 317 Query: 339 LPELK--PHWNREADLLTKAVTIAWSNIQKHTDQLTQAAMTDLLTGLANRRSLELTMNQW 396 L +K W EA L +A+ +L A+TD LTGL NRR + + Sbjct: 318 LERIKTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDPLTGLYNRRGVANALRLH 377 Query: 397 IAAQFSFSVIVLDVDKFKFVNDTYGHLAGDEVLKQVADILKMSIRPGDVCCRYGGEEFVV 456 FS + LDVD FK +ND +GH GD+VL+ +A +++ R GD+ R GGEEF++ Sbjct: 378 AGRHQPFSAVTLDVDHFKRINDRHGHDVGDQVLRHLAALIREQARHGDITGRIGGEEFIL 437 Query: 457 LLPRTKASDAYTVAERIRKTLEXXXXXXXXXXXXXXGIAHYPSHGSSLEELLQQADRAMY 516 LLP A+ AER+R +E G+AHYP ++ +L+ +D A+Y Sbjct: 438 LLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQSAGEVDAVLKLSDLALY 497 Query: 517 KAKGLGRNRTVI 528 +AK GRNRTV+ Sbjct: 498 QAKRDGRNRTVV 509 >aq_035_2 [T] COG2199 FOG: GGDEF domain Length = 251 Score = 124 bits (312), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 66/167 (39%), Positives = 104/167 (62%), Gaps = 9/167 (5%) Query: 373 QAAMTDLLTGLANRRSL-ELTMNQWIAAQ---FSFSVIVLDVDKFKFVNDTYGHLAGDEV 428 + A+TD LTGL NRR E+ + A+ ++FS++++D+D FK +NDTYGH GD V Sbjct: 82 RMALTDPLTGLYNRRVFTEMAEKELAKAKRYGYNFSILMIDIDNFKKINDTYGHDVGDLV 141 Query: 429 LKQVADILKMSIRPGDVCCRYGGEEFVVLLPRTKASDAYTVAERIRKTLEXXXXX----X 484 LK++++ILK ++R D+ R+GGEEF+V+L T + A AE++R+ +E Sbjct: 142 LKKISEILKRNVRGADLVARFGGEEFIVMLSNTNLNGAVKKAEQLRRMIEQTPIELPNGE 201 Query: 485 XXXXXXXXGIAHYPSHGSSLEELLQQADRAMYKAKGLGRNRTVIAEE 531 G++ Y H SLEEL+++AD+A+Y+AK G+NR + E Sbjct: 202 KLRVTVSIGVSTYRGH-ESLEELIKEADQALYEAKRKGKNRVEVFRE 247 >AGc2387 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 218 Score = 122 bits (307), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 0/176 (0%), Positives = 0/176 (0%), Gaps = 13/176 (7%) Query: 363 NIQKHTDQLTQAAMTDLLTGLANRRSLE----LTMNQWIAAQFSFSVIVLDVDKFKFVND 418 Sbjct: 283 ---- 338 Query: 419 TYGHLAGDEVLKQVADILKMSIRPGDVCCRYGGEEFVVLLPRTKASDAYTVAERIRKTLE 478 Sbjct: 339 398 Query: 479 -----XXXXXXXXXXXXXXGIAHYPSHGSSLEELLQQADRAMYKAKGLGRNRTVIA 529 Sbjct: 399 454 >ECs1925_3 [T] COG2199 FOG: GGDEF domain Length = 170 Score = 121 bits (303), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 67/165 (40%), Positives = 95/165 (57%), Gaps = 5/165 (3%) Query: 369 DQLTQAAMTDLLTGLANRRSL----ELTMNQWIAAQFSFSVIVLDVDKFKFVNDTYGHLA 424 +QL AA D +TGL NRR E Q +A +S++++D D+FK +ND YGH Sbjct: 7 EQLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHINDLYGHSK 66 Query: 425 GDEVLKQVADILKMSIRPGDVCCRYGGEEFVVLLPRTKASDAYTVAERIRKTLEXXXXXX 484 GDEVL +A L+ R GD+ R+GGEEFV+LLPRT A ++AE IR ++ Sbjct: 67 GDEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVSVAKVSISG 126 Query: 485 XXXXXXXXGIAHYPSHGSSLEELLQQADRAMYKAKGLGRNRTVIA 529 G+AH+ S++EL ++ D A+Y+AK GRNR + A Sbjct: 127 LPRFTVSIGVAHHEG-NESIDELFKRVDDALYRAKNDGRNRVLAA 170 >Z2421_3 [T] COG2199 FOG: GGDEF domain Length = 170 Score = 121 bits (303), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 67/165 (40%), Positives = 95/165 (57%), Gaps = 5/165 (3%) Query: 369 DQLTQAAMTDLLTGLANRRSL----ELTMNQWIAAQFSFSVIVLDVDKFKFVNDTYGHLA 424 +QL AA D +TGL NRR E Q +A +S++++D D+FK +ND YGH Sbjct: 7 EQLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHINDLYGHSK 66 Query: 425 GDEVLKQVADILKMSIRPGDVCCRYGGEEFVVLLPRTKASDAYTVAERIRKTLEXXXXXX 484 GDEVL +A L+ R GD+ R+GGEEFV+LLPRT A ++AE IR ++ Sbjct: 67 GDEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVSVAKVSISG 126 Query: 485 XXXXXXXXGIAHYPSHGSSLEELLQQADRAMYKAKGLGRNRTVIA 529 G+AH+ S++EL ++ D A+Y+AK GRNR + A Sbjct: 127 LPRFTVSIGVAHHEG-NESIDELFKRVDDALYRAKNDGRNRVLAA 170 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.132 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 32,161,622 Number of extensions: 1179321 Number of successful extensions: 2234 Number of sequences better than 1.0e-05: 143 Number of HSP's gapped: 2055 Number of HSP's successfully gapped: 143 Length of query: 531 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 420 Effective length of database: 25,576,357 Effective search space: 10742069940 Effective search space used: 10742069940 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)