BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0584.0042.p (157 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR0004 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 82 2e-16 SPy0477 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 76 2e-14 BH1893 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 72 3e-13 DR0329 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 69 3e-12 YPO0786 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 63 2e-10 >DR0004 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 10/135 (7%), Positives = 29/135 (21%), Gaps = 5/135 (3%) Query: 5 EYYRSLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQ-----LWGLPAGAIEPGETP 59 + + L++ + V + + I L Q + L + Sbjct: 178 CNVLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARF 237 Query: 60 SRALRREVFEETGLMVNPLRIIGVFGGEKYTYEYINGDRVQYSVIVFECAIVKGTLRSVD 119 + + + P ++ + + S + + A + Sbjct: 238 TVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHV 297 Query: 120 GEAEELVFFSGDELP 134 E Sbjct: 298 FEKRLFSELGYGAEL 312 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 13/144 (9%), Positives = 35/144 (24%), Gaps = 8/144 (5%) Query: 1 MPISEYYRSLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPS 60 M ++ + V L++ + + + G A+ + Sbjct: 1 MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60 Query: 61 RALRREVFEETGLMVNPLRII----GVFGGEKYTYEYINGDRVQYSVIVFECAIVKGTLR 116 R ++ V + G +I + G + +S+ + Sbjct: 61 REMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKEL 120 Query: 117 SV----DGEAEELVFFSGDELPEL 136 + D + S + Sbjct: 121 TEGLIEDDKVLLQQLISTISNWKN 144 >SPy0477 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 13/140 (9%), Positives = 31/140 (22%), Gaps = 9/140 (6%) Query: 1 MPISEYYRSLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPS 60 M + + +G +V + A + + + A + Sbjct: 1 MR-LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKA 59 Query: 61 RALRREVFEETGLMVNPLRIIGVFGGEKYTYEYINGDRVQYSVIVFECAIVKGTLRSVDG 120 +E +T ++ I + ++ T Sbjct: 60 AREMKERVGQTLGRKEARGLMISTF--HTLGLDIIKREYAALGMKANFSLFDDT--DQLA 115 Query: 121 ----EAEELVFFSGDELPEL 136 E L+ L +L Sbjct: 116 LLKELTEGLIEDDKVLLQQL 135 >BH1893 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 4/129 (3%), Positives = 23/129 (17%), Gaps = 1/129 (0%) Query: 6 YYRSLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPSRALRR 65 + + L+ A + + + Sbjct: 27 GKTRVITNKIAHLIRGCGYQARHIAAVTFTNK-AAREMKERVGQTLGRKEARGLMISTFH 85 Query: 66 EVFEETGLMVNPLRIIGVFGGEKYTYEYINGDRVQYSVIVFECAIVKGTLRSVDGEAEEL 125 + + + + + + ++ + ++ L S + Sbjct: 86 TLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKND 145 Query: 126 VFFSGDELP 134 + Sbjct: 146 LKTPSQAAA 154 >DR0329 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 8/129 (6%), Positives = 24/129 (18%), Gaps = 1/129 (0%) Query: 6 YYRSLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPSRALRR 65 ++ + LL + A + +R + + R Sbjct: 176 KACNVLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRA 235 Query: 66 EVFEETGLMVNPLRIIGVFGGEKYTYEYINGDRVQYSVIVFECAIVKGTLRSVDGEAEEL 125 + G + ++ + L++ + Sbjct: 236 RFTVVGDDDQSIYSWRGARPQNLVLLSQ-DFPALKVIKLEQNYRSSGRILKAANILIANN 294 Query: 126 VFFSGDELP 134 L Sbjct: 295 PHVFEKRLF 303 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 10/138 (7%), Positives = 25/138 (18%), Gaps = 10/138 (7%) Query: 9 SLRNKVGSGLLMVPSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPSRALRREVF 68 + V +A + I + G A I ++A R Sbjct: 6 GQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKE 65 Query: 69 EETGLMVNPLRIIGVFGG-----EKYTYEYINGDRVQYSVIVFECAIVKGTLRSVD---- 119 + + + + + L Sbjct: 66 RVGQTLGRKEARGLMISTFHTLGLDII-KREYAALGMKANFSLFDDTDQLALLKELTEGL 124 Query: 120 GEAEELVFFSGDELPELA 137 E ++++ Sbjct: 125 IEDDKVLLQQLISTISNW 142 >YPO0786 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 7/61 (11%), Positives = 12/61 (19%) Query: 22 PSVAAVIRNEEGDILLLRKGGEQLWGLPAGAIEPGETPSRALRREVFEETGLMVNPLRII 81 +V V + A I +R + F R+ Sbjct: 9 QAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVG 68 Query: 82 G 82 Sbjct: 69 Q 69 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.142 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,927,143 Number of extensions: 591056 Number of successful extensions: 1189 Number of sequences better than 1.0e-05: 37 Number of HSP's gapped: 1212 Number of HSP's successfully gapped: 39 Length of query: 157 Length of database: 38,378,431 Length adjustment: 98 Effective length of query: 59 Effective length of database: 27,075,699 Effective search space: 1597466241 Effective search space used: 1597466241 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 111 (47.4 bits)