BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0580.0044.p (532 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 191 2e-48 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 170 6e-42 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 155 1e-37 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 146 1e-34 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 141 2e-33 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 191 bits (486), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 154/549 (28%), Positives = 272/549 (49%), Gaps = 58/549 (10%) Query: 8 YKVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVI 67 YKVLL DDE + LK I WE+ G +A EA NGE A +L++E P ++I+DIRMPV Sbjct: 2 YKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVF 61 Query: 68 DGIALMKEV---LPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTR 124 DG+ L+++V L ++K FI ISGY +F YA++A+R GA D++LKPID DEL L + Sbjct: 62 DGLQLIQKVNETLSFNTK--FIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIK 119 Query: 125 AIARLKRQK----ENEQLMLS---VQTLSMLARE----RMYAEFTLGNPRPLQHLKWLEN 173 A L ++K + E+++L + +L +E R A+ + N R + LE Sbjct: 120 LAATLDQEKATNSDQEKVLLDQIFIHSLGENKKENEVRRWAAKLNINN-RHFYYYLLLEV 178 Query: 174 SELE------GEYFMAVVRLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFP 227 + L E + +R ++ Q + EE I E+ G+L Sbjct: 179 NNLSLDKGFINEQYKEPIRKVIRETVARQAATEE-------YTAIYEQLDHAYGLLIT-- 229 Query: 228 FYNGEWILLFPGSLGSVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACK 287 E + F G + + L E+L I+ ++ + +V + T + + Y A Sbjct: 230 ---SEHLKKFNGQI----EPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANS 282 Query: 288 ALYQRFYSGQAGVFIDEETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDEM-SAF 346 ++ + VFI E+T + + + L + L+E + + +R++++ D++ S F Sbjct: 283 LRNYKYIFNEKNVFIHEQTESVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEF 342 Query: 347 IEAQGLPQELAERLIIEMIVVLYRQFEHLNLHTDWSLEGLLSRLHGLGTLSA------MI 400 + +P A + + V H + T ++EG ++ ++ Sbjct: 343 QTKKFVPS--AVKTSVNRCV-------HKVMQTVQAMEGDTGKIISAQAMTNWESYNLTF 393 Query: 401 AALKMEFSEWMLGSN---KSATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVADLSISH 457 LK F++++L + + +E+ +S + K YIE +YH+++S++ +A + ++ + Sbjct: 394 DQLKQVFTKFVLEAAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVY 453 Query: 458 FCTLFKQISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATG 517 LFK+ G F E++ RM +AK +L+ ++++VY+VA VG+ YF F+K Sbjct: 454 MGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINK 513 Query: 518 KTPTEYREE 526 TPTEYR + Sbjct: 514 MTPTEYRNK 522 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 170 bits (430), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 142/536 (26%), Positives = 264/536 (49%), Gaps = 44/536 (8%) Query: 10 VLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVIDG 69 VL+VDDE I LK+ + + + I GEA NG A++ ET P +++ DI+MP +DG Sbjct: 4 VLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGVDG 62 Query: 70 IALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRAIARL 129 + +KE+ + + FI +S + FEYARE +R G +YLLKP +++ L R + + Sbjct: 63 VQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIVGEI 122 Query: 130 K--RQKENEQLMLS--VQTLSMLARERMYAEFTLGNPRPLQHLKWLENSELEGEYFMAVV 185 + R+++N+Q L ++ +S + + + + + ++W E E E + V Sbjct: 123 EQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNEWLRTEQEGYAVVF 182 Query: 186 RLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEW-ILLFPGSLGSV 244 ++ + EK+ W ++ +E L+ +V PF IL+ + + Sbjct: 183 ---SFHQQGKEIRKTEKQQWHARIK---KEIGLQLPKSTVGPFIGHHLPILMLTENENGM 236 Query: 245 SKELGEQLISGIRKYSKLECSVGISRITRGIDQL------STVYPLACKALYQRFYSGQA 298 +K+ EQ++ I+ K++ +V +++ G+ + ST Y A AL + QA Sbjct: 237 TKQEREQVV--IQLLHKVKQAVQPAKVKTGVGGIYRLHFFSTSYREALLALDIIYDHKQA 294 Query: 299 GVFIDEETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDE-MSAFIEAQGLPQELA 357 + ++ + E + P E E LIE+I++ D E+ L FD + A + P Sbjct: 295 SYYFYDKNVKIRADE-QLPIERENKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHDM 353 Query: 358 ERLIIEMIVVLYRQFEHLNLHTDWSLEGLLSRL--------HGLGTLSAMIAALKMEFSE 409 + + ++ ++L R + LH W +R HG + ++ L+ E Sbjct: 354 RKYLQQLFIILGRLLNEMGLH--WETAQDFARFSTVHQVTEHGKSEILHIVRTLQ----E 407 Query: 410 WMLGSNKSATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVADLSISHFCTLFKQISGYT 469 W D +S++ + Y+ ++ + L+++++A+ LS + LFK+ T Sbjct: 408 WRTT--------DEQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLT 459 Query: 470 FLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTEYRE 525 F E+VT R+E AK +L + + ++ +GY+DP YF++VFKK TGK+P++YR+ Sbjct: 460 FSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYRK 515 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 155 bits (393), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 138/553 (24%), Positives = 248/553 (44%), Gaps = 71/553 (12%) Query: 8 YKVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVI 67 +KV+++DDE ++R LK I W+ LG GEA NG L ++ ET+P I+++DI MP++ Sbjct: 2 WKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPIM 61 Query: 68 DGIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRAIA 127 G+ +++ + + +SGY EFE+AR+A++ DYL KP D + +L R I Sbjct: 62 YGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVIN 121 Query: 128 RLKRQKENEQLMLSVQTLSMLARERMYAEFTLGNPRPLQHLKW--------LENSELEGE 179 +L+ +K+ +Q L T + E PL +W L N E+ E Sbjct: 122 KLE-EKQRQQGYLQELTNKVKRYE------------PLVETEWMKSLLTGRLRNGEIPEE 168 Query: 180 YFMAVVRLDNYASLTAQWSVEEKR----------LWLFAVRNILEEWSLENGVLSVFPF- 228 + + + + + + + + L+ ++V ++ E VL+ +P Sbjct: 169 FLAKITKWKDQQHIACSLTYDGPQNKELKPADWYLFRYSVHKMIRE------VLNGYPID 222 Query: 229 --------YNGEWILLFPGS-----LGSVSKELGEQLISGIRKYSKLECSVGISRITRGI 275 Y L S L + E+ +Q+ GI ++ +V R+ Sbjct: 223 FRYLEMDAYRSALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDW 282 Query: 276 DQLSTVYPLACKALYQRFYSGQAGVFIDEETAAGGSREVKYPKELELALIESIRTVDLER 335 LS + AC Q F G G+R +P E L ++IR D R Sbjct: 283 TDLSESFHEACME-SQSFPLGNP--------YEDGTR-ATFPMESSQKLYDAIRYADATR 332 Query: 336 MLSLFDEMSAFIEAQGLPQELAERLIIEMIVVLYRQFEHLNL------HTDWSLEGLLSR 389 + +E + + ++ IE+ ++ + + D+ L L++ Sbjct: 333 AKEVLEEAVGVLGEVPYSTLVGYKVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTK 392 Query: 390 LHGLGTLSAMIAALKMEFSEWMLGSNKSATREDGRSVVEKSMRYIEANYHKDLSIEEVAE 449 G I L E E + + + ++E+ M YIE + ++++++++A+ Sbjct: 393 ---QGNWQEWIRFL-CEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIAD 448 Query: 450 VADLSISHFCTLFKQISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFT 509 +S ++ +FK++ G +F +VT RMEKAK ++Q N +Y+V+ VGY +P YFT Sbjct: 449 ELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFT 508 Query: 510 QVFKKATGKTPTE 522 +FKK TG TP + Sbjct: 509 TMFKKYTGYTPRD 521 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 146 bits (368), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 139/546 (25%), Positives = 252/546 (46%), Gaps = 73/546 (13%) Query: 8 YKVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVI 67 Y V++VDDE ++ LK I WEE G + ARNG+ + +P ++I DIRMP + Sbjct: 2 YDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEV 61 Query: 68 DGIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRAIA 127 DG++L++ + S + FI +SG+ +F YA++AL DYLLKP+D DEL + L + Sbjct: 62 DGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVYG 121 Query: 128 RLKRQKENEQLMLSVQTLSMLARERMYAEFTLGNPR---PLQHLKWLENSELEGEYFMAV 184 R+ R + +L+ VQ + E + E G P P+ E++ +Y +A+ Sbjct: 122 RITRHHQVHELVERVQEKQV---EMVLTELLEGTPLSEIPIGK----EHNFFATDYQVAL 174 Query: 185 VRLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEWILLFPGS--LG 242 V + LT Q ++ ++EE E G + FP E+I++ + L Sbjct: 175 VE-NRQDRLTKQ------------LKRLIEEQ--EEGYVIPFP----EYIVIVCKNRFLQ 215 Query: 243 SVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYP--LACKALYQRFYSGQAGV 300 K+ L + + +L G S++ L+ +Y + K LY++ + + G Sbjct: 216 KRGKDHRYHLFAKWLEEEELHACAG-SKVV----NLADIYESYQSAKRLYEKKFFVEKGR 270 Query: 301 FIDEETAAGGSREVKYPKELELA-------LIESIRTVDLERMLSLFDEMSAFIEAQGLP 353 + S+ P+ E + L SI ++E +++ +E+ + + Sbjct: 271 LFTADQLVDRSK----PEAPEFSLESYADRLYYSIDIGNMEGCVAIIEELKNVV----IV 322 Query: 354 QELAERLIIEMIVVLYRQFEHLNLHTDWSLEGLLSRL-----------HGLGTLSAMIAA 402 E+ I + LY H + + ++EG+L L H G ++ + Sbjct: 323 HLQEEKEIKVALFQLYSNILHQLVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQ 382 Query: 403 LKMEFSEWMLGSNKSATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVADLSISHFCTLF 462 LK +++ + + ++ K + I +Y K+L +E +A V + + ++ LF Sbjct: 383 LK-----YVIDCMDNGQPD---LLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLF 434 Query: 463 KQISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTE 522 K +G F ++ R+E K +LQ KVY+VA +GY + YF + FKK G +P+ Sbjct: 435 KNYTGEYFNTYLDKVRIENGKRLLQKG-YKVYEVAEKIGYANVDYFHRKFKKYVGVSPST 493 Query: 523 YREENS 528 +R+ + Sbjct: 494 FRKRHD 499 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 141 bits (356), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 141/534 (26%), Positives = 238/534 (44%), Gaps = 49/534 (9%) Query: 10 VLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVIDG 69 VL+VDDE +I + + WE+ G I GEA NG+ AL+LI + P I+++DI MPV+DG Sbjct: 4 VLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMDG 63 Query: 70 IALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKP-IDHDELTEMLTRAIAR 128 I L+K V ++ I +S + EFEY R G DY+LKP ++ +L + L+ + Sbjct: 64 IDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDLLKTLSEVRGK 123 Query: 129 LKRQKENEQLMLSVQTLSMLARERMYAEFTLGNPRPLQHLKWLENSELEGEYFMAVVRLD 188 + + + +V ++S E L PL E +G Y +AV+ Sbjct: 124 IPALAKVDSPSRAVPSIS------DQFEKILNGHAPLSQDDTGEKRFPKGPYRLAVI--- 174 Query: 189 NYASLTAQWSVEEKRLWLF----AVRNILEEWSLENGVLSVFPFYNGEWILLFP--GSLG 242 + + V ++ L A+ I S+E G+ +LL P G + Sbjct: 175 ---TPIEEQDVHRRKQHLDEREQAITGIDVVCSIEK---------EGDAVLLLPLEGDVS 222 Query: 243 SVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACKALYQ-RFYSGQAGVF 301 S K+ + + G ++ L +S I + VY L Q FY + Sbjct: 223 SSMKQALDDFLKGRDAHALL-----VSSPFSSIYEAKEVYERDIPLLKQYSFYLPDTPLL 277 Query: 302 IDEETAAG--GSREVKYPKELELALIESIRTVDLERMLSLFDEMSA-FIEAQGLPQELAE 358 I +E G + +EL + + +L + MS + + + Sbjct: 278 IYDELPKTNEGVKTFDLNHFIELCKGRKF-AIGFQYLLDYVEYMSTRYTQTSTECKAFLG 336 Query: 359 RLIIEMIVVLYRQFEHLNLHTDWSLEGLLSRLHGLGTLSAMIAALKME--FSEWMLGSNK 416 +I MIV++ NL D E + H T++A + F +++ + + Sbjct: 337 NIIFNMIVLM------GNLKYDVK-ELEREKYHYFATINAAKNVREATDCFYQFLEVTKQ 389 Query: 417 --SATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVADLSISHFCTLFKQISGYTFLEFV 474 S +G S ++K + YIE ++ + LS+ ++A + S+ F+Q F E++ Sbjct: 390 IISVYSNEGSSSIQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYL 449 Query: 475 THCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTEYREENS 528 R+ KAK L++S + + ++ LVGY D YF +VFKK TG P+ YR EN+ Sbjct: 450 NKVRIRKAKEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRRENA 503 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,488,130 Number of extensions: 1498885 Number of successful extensions: 4879 Number of sequences better than 1.0e-05: 361 Number of HSP's gapped: 4956 Number of HSP's successfully gapped: 371 Length of query: 532 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 421 Effective length of database: 25,576,357 Effective search space: 10767646297 Effective search space used: 10767646297 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)