BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0580.0042.p
         (414 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SPy0543 [GEPR] COG0477 Permeases of the major facilitator superf...    53   7e-07
CAC0458 [GEPR] COG0477 Permeases of the major facilitator superf...    51   3e-06

>SPy0543 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 402

 Score = 53.1 bits (126), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 55/223 (24%), Positives = 107/223 (47%), Gaps = 17/223 (7%)

Query: 11  RNKYVRTVVMSRVLLQLGVWVRNFAILLYVTEITNNDPFYVSLISV---VEFAPIFLFAI 67
           R K ++ +V S+V+ ++G  + +FA     T +   +P  +SL++V   +E     LF +
Sbjct: 4   RKKNIQYLVYSKVIYRIGDVMFDFA---NNTFLAGLNPASLSLVAVYQSLESVIGVLFNL 60

Query: 68  VGGTFADRWRPKKTMIWSDXXXXXXXXXXXXXXMGGSW--KALLLATFVSAVLSQFSQPS 125
            GG  AD ++ KK +I ++                  W   A++L   + A +S FS PS
Sbjct: 61  FGGVIADSFKRKKIIITTNILCGTACLVLSFLT-KEQWLVYAIVLTNVILAFMSAFSSPS 119

Query: 126 AMKLFKQHVPESQLQGVMAMFQSLTAFFMVIGPVLGAFIYQHYGIEVSLXXXIIMAGM-F 184
                K+ V +  +  + ++ ++ +    V  P++  F+Y+  GI       +++ G+ F
Sbjct: 120 YKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIH----GVLLLDGLSF 175

Query: 185 AGSALILS-LLPKDNAETAGHKQT--GIYAEVKAGLSYVRTSK 224
             +AL++S +LP ++      K T   I+ ++K G  YV + K
Sbjct: 176 LIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHK 218


>CAC0458 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 409

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/219 (20%), Positives = 88/219 (40%), Gaps = 19/219 (8%)

Query: 16  RTVVMSRVLLQLGVWVRNFAILLYVTEITNNDPFYVSLISVVEFAPIFLFAIVGGTFADR 75
           +  ++ + +  +G W++  A +  +  +T   P  +  +SV +F P  +F++  G   DR
Sbjct: 18  KCFIIGQSISLMGTWLQRTAEVWLLYTLTK-SPLLLGSLSVFQFGPTLIFSVFSGAIVDR 76

Query: 76  WRPKKTMIWSDXXXXXXXXXXXXXXMGGSWKALL---LATFVSAVLSQFSQPSAMKLFKQ 132
           +  KK +  +                     A+L   LAT +  + +    P+    F +
Sbjct: 77  FPKKKLLYLTQTVGMLQALALFILVYTNHITAILIFILAT-IGGLSTTLDMPTRQSYFME 135

Query: 133 HVPESQLQGVMAMFQSLTAFFMVIGPVLGAFIYQHYGIEVS-----LXXXIIMAGMFAGS 187
            V +  L   +++  S+     +IGP +   I   +G+ V      L    ++ G+F   
Sbjct: 136 LVGKKDLPNAVSLNSSIFNLAKIIGPSIAGIIMGKFGMSVCFFINFLSYAAVLTGLF--- 192

Query: 188 ALILSLLPKDNAETAGHKQTGIYAEVKAGLSYVRTSKVL 226
                   K  +  A      I+ E+K GL Y+  +K+L
Sbjct: 193 ------FIKQKSYAANISSDNIFKEIKEGLKYIYENKIL 225


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.327    0.140    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 22,485,402
Number of extensions: 727545
Number of successful extensions: 1744
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 1748
Number of HSP's successfully gapped: 4
Length of query: 414
Length of database: 38,378,431
Length adjustment: 109
Effective length of query: 305
Effective length of database: 25,807,025
Effective search space: 7871142625
Effective search space used: 7871142625
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 117 (49.7 bits)