BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0580.0015.p
         (265 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SP0717 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family   151   1e-36
SP0724 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family    92   1e-18

>SP0717 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
          Length = 260

 Score =  151 bits (381), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 93/262 (35%), Positives = 136/262 (51%), Gaps = 3/262 (1%)

Query: 1   MSFLTKVRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNI 60
           M+ L  ++E  PLV  ITN VV NF+ANGL+ALGASP M++   ++ D+   +G +++NI
Sbjct: 1   MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPADLEDLLKYAGGLLINI 60

Query: 61  GTLNDYAIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAE 120
           GTL D   +    A K A ++NVP VLDPV  GA  YR +V   L++  ++ A+RGN  E
Sbjct: 61  GTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVADDLINNYKLAAIRGNAGE 120

Query: 121 VAHVVGERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVI-TNGRITYVVSNG 179
           +A +VG   +                            ++TG+ D I  NG +  ++ NG
Sbjct: 121 IASLVGIDVA-SKGVDSAGVDNIDEIALAANEKFNIPIVVTGEVDAIAVNGEVV-MIHNG 178

Query: 180 HPVLTRVTGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQ 239
             ++ +V GTGCLL AVV +F+                 Y +A EIA  R      G+F+
Sbjct: 179 SAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLKTAVLVYNIAGEIAEKRPNGHLPGTFK 238

Query: 240 TEFLNQLALVTPEVYAERSRVQ 261
            EF+N L  +T E   E  RV+
Sbjct: 239 VEFINALYEITDEDVKEFKRVK 260


>SP0724 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
          Length = 267

 Score = 91.7 bits (226), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 68/246 (27%), Positives = 113/246 (45%), Gaps = 12/246 (4%)

Query: 10  NNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDYAIE 69
           ++ L+H ITN +     ANG+LALG  P MAD   EV D    S A+ +N+G L+    +
Sbjct: 12  SSSLIHCITNEISCEMLANGILALGCKPVMADDSREVLDFTKQSQALFINLGHLSAEKEK 71

Query: 70  SMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVGERW 129
           ++ +A   AN+ ++P+V+D VG   ++ R  +   L+   + T L+GN++E+  +VG + 
Sbjct: 72  AIRMAASYANQSSLPMVVDAVGVTTSSIRKSLVKDLLD-YRPTVLKGNMSEIRSLVGLKH 130

Query: 130 S----IXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTR 185
                                            ++TG +D++ +     V+ NG   L  
Sbjct: 131 HGVGVDASAKDQETEDLLQVLKDWCQTYPGMSFLVTGPKDLVVSKNQVAVLGNGCTELDW 190

Query: 186 VTGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVG--SFQTEFL 243
           +TGTG L+ A+   FL                       IAA +   QG+G   F+ + L
Sbjct: 191 ITGTGDLVGALTAVFLSQGKTGFEASCLAVSYL-----NIAAEKIVVQGMGLEEFRYQVL 245

Query: 244 NQLALV 249
           NQL+L+
Sbjct: 246 NQLSLL 251


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.319    0.132    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 15,163,630
Number of extensions: 473154
Number of successful extensions: 6339
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 6337
Number of HSP's successfully gapped: 3
Length of query: 265
Length of database: 38,378,431
Length adjustment: 104
Effective length of query: 161
Effective length of database: 26,383,695
Effective search space: 4247774895
Effective search space used: 4247774895
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 115 (48.9 bits)