BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0579.0028.p (335 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1949 [K] COG1609 Transcriptional regulators 209 4e-54 BS_kdgR [K] COG1609 Transcriptional regulators 200 2e-51 RSc1014 [K] COG1609 Transcriptional regulators 199 4e-51 CAC0393 [K] COG1609 Transcriptional regulators 193 3e-49 VC1721 [K] COG1609 Transcriptional regulators 180 3e-45 >PA1949 [K] COG1609 Transcriptional regulators Length = 337 Score = 209 bits (533), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 119/308 (38%), Positives = 178/308 (57%), Gaps = 4/308 (1%) Query: 4 ATIGDVAARAGVSKSTVSQFLNKRYQHMGQETRIKIEEAIEALDYRPNVLARGLKQKRTG 63 AT+ DVAA AGVS +TVS +N R + + R K+E+AI L Y P+ +AR LK + T Sbjct: 2 ATMKDVAAMAGVSFTTVSHVVN-RTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTS 60 Query: 64 AVGVIVANIMHRLSTEICRGIEDYCQEQNVNVILCNSDEDGEKEKKYAEMLQAKQVDGII 123 +G++V N + E+ RGIED C+ VILCNSD++ +K+ Y +LQ K++DG++ Sbjct: 61 IIGLLVPNSTNPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLRVLQEKRIDGLV 120 Query: 124 LLPTGKNGALYESLAGQGYPILFMDRRVDNVKADTIVVNNREAVTQAVKHLASLGHRSIA 183 L G +GAL + LA P + +DR V+ V+AD + +++ A +HL LGHR IA Sbjct: 121 LASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRHLLELGHRDIA 180 Query: 184 LATGPLTISTRTERTEGFRTAMSMLGLDYGSCNIINVEISS---LKDRLRKRFEGQEPPT 240 GPL+ T R EG+R AM+ GL+ ++ E SS L E PT Sbjct: 181 CIGGPLSTKVSTLRVEGYRRAMAKAGLEVRPQWLLESEFSSPGGYHAALGLLGGEGERPT 240 Query: 241 ALIAGNDLVLLEALAFVKEQGLRVPEDLALVAFDNIPFAHLLTPTLTTINQPSLEMGRKA 300 A++AGND++ + L E +RVP +L+++ FD+I + + P LTT+ Q +G A Sbjct: 241 AIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIELSRFVFPALTTVGQSIRLLGEIA 300 Query: 301 AERLITRI 308 A+ L+ RI Sbjct: 301 AQLLLQRI 308 >BS_kdgR [K] COG1609 Transcriptional regulators Length = 339 Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 111/312 (35%), Positives = 189/312 (60%), Gaps = 6/312 (1%) Query: 2 GKATIGDVAARAGVSKSTVSQFLNKRYQHMGQETRIKIEEAIEALDYRPNVLARGLKQKR 61 G TI DVA AGVSKSTVS+++N + + E I++AI L+YRP+ +A+GLK K+ Sbjct: 7 GHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKK 66 Query: 62 TGAVGVIVANIMHRLSTEICRGIEDYCQEQNVNVILCNSDEDGEKEKKYAEMLQAKQVDG 121 + +G +VA+I + S RG+E+ C + ++++CN+D EKE++ L+A V+G Sbjct: 67 SKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEG 126 Query: 122 IILLPTGKNGALYESLAGQGYPILFMDRRVDNVKADTIVVNNREAVTQAVKHLASLGHRS 181 +IL TG+N + + A Q P + +DR++ ++K DT+ +NR + ++ + S G+ Sbjct: 127 LILNATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVYSKGYTD 186 Query: 182 IALATGPL-TISTRTERTEGFRTAMSMLGLDYGSCNIINVEISS---LKDRLRK-RFEGQ 236 +AL T P+ +IS R ER ++ S+ ++ G + +++ LK LR E Sbjct: 187 VALFTEPISSISPRAERAAVYQEMASVQNVN-GLVRLHEIDVKDKEQLKAELRSFHKEMP 245 Query: 237 EPPTALIAGNDLVLLEALAFVKEQGLRVPEDLALVAFDNIPFAHLLTPTLTTINQPSLEM 296 E A++A N L++L+ ++ ++E GLR+P+D+ + FD+ + L+ P +TTI QPS +M Sbjct: 246 EQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDM 305 Query: 297 GRKAAERLITRI 308 GR A ER++ RI Sbjct: 306 GRTAMERVLKRI 317 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 111/304 (36%), Positives = 171/304 (56%), Gaps = 3/304 (0%) Query: 4 ATIGDVAARAGVSKSTVSQFLNKRYQHMGQETRIKIEEAIEALDYRPNVLARGLKQKRTG 63 ATI DVAA AGVS +TVS +N + + ETR ++EEAI A Y P+ +AR LK + T Sbjct: 2 ATIKDVAALAGVSFTTVSHVINN-TRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTR 60 Query: 64 AVGVIVANIMHRLSTEICRGIEDYCQEQNVNVILCNSDEDGEKEKKYAEMLQAKQVDGII 123 +GV+V + E+ RGIED C +VILCNSD+D K++ Y +L K+VDG+I Sbjct: 61 TIGVLVPTATNPYFAELARGIEDVCAAAGYSVILCNSDDDPRKQRDYLRVLMEKRVDGLI 120 Query: 124 LLPTGKNGALYESLAGQGYPILFMDRRVDNVKADTIVVNNREAVTQAVKHLASLGHRSIA 183 + G + AL ++L P++ +DR + + AD + +++ E A +HL LGHR IA Sbjct: 121 VSSAGPDNALLDALGESALPVVMVDRPTEGILADQVQIDHEEGAYLATRHLLELGHRRIA 180 Query: 184 LATGPLTISTRTERTEGFRTAMSMLGLDYGSCNIINVEISSLKDR--LRKRFEGQEPPTA 241 +GP T+S R GF A+ G+ + + + +S R+ E PTA Sbjct: 181 CISGPSTLSVTAGRLAGFHRALREAGVPEHAARVAEGDFTSPGGYRAARELLTTGETPTA 240 Query: 242 LIAGNDLVLLEALAFVKEQGLRVPEDLALVAFDNIPFAHLLTPTLTTINQPSLEMGRKAA 301 + A NDL+ + AL E G+ VP++L+++ FD+I + + P L+T+ Q ++G A Sbjct: 241 IFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQLGETTA 300 Query: 302 ERLI 305 L+ Sbjct: 301 STLL 304 >CAC0393 [K] COG1609 Transcriptional regulators Length = 344 Score = 193 bits (491), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 109/310 (35%), Positives = 182/310 (58%), Gaps = 5/310 (1%) Query: 3 KATIGDVAARAGVSKSTVSQFLNKRYQHMGQETRIKIEEAIEALDYRPNVLARGLKQKRT 62 K I DVA AGVSK+T+S++LN ++++M ++T+ +I+E+IE L+YRPN +AR LK ++ Sbjct: 6 KVVIDDVAKLAGVSKATISRYLNGKFEYMSEKTKDRIKESIEELNYRPNNIARSLKSNKS 65 Query: 63 GAVGVIVANIMHRLSTEICRGIEDYCQEQNVNVILCNSDEDGEKEKKYAEMLQAKQVDGI 122 +GV++A++ + S+ I +GI D C+ + N+++ NSD D ++E++Y + L ++V+GI Sbjct: 66 KLIGVVIADLTNPFSSIIIKGIGDECKARGYNMVIANSDNDVKQEEEYIKSLLDQRVEGI 125 Query: 123 ILLPTGKNGALYESLAGQGYPILFMDRRVDNVKADTIVVNNREAVTQAVKHLASLGHRSI 182 I+ TG N S+ +G P+ +DR K D++ NN + + + +L G S+ Sbjct: 126 IVNSTGYNEEFLLSIKERGIPVSMVDRTFCEDKVDSVKSNNYDITVETINYLIDAGFNSL 185 Query: 183 ALATGPL-TISTRTERTEGFRTAMSMLGLDYGSCNIINVEIS---SLKDRLRKRFEGQEP 238 T L I R ER F S L + NI V+ S +L+ + K Sbjct: 186 CFFTERLDNIKPRIERERAFIDVCSKR-LKKENYNISVVDYSKAGNLEVNIYKFLNNYSG 244 Query: 239 PTALIAGNDLVLLEALAFVKEQGLRVPEDLALVAFDNIPFAHLLTPTLTTINQPSLEMGR 298 A+ A N +VLL L+ + + + VP+DL + +DN +A L+ P +TTI+QPS EMG Sbjct: 245 KKAIFAVNGVVLLHTLSAINKLNINVPKDLGICGYDNWGWAALIPPGITTISQPSYEMGS 304 Query: 299 KAAERLITRI 308 +AA+ ++ RI Sbjct: 305 EAAKLVLDRI 314 >VC1721 [K] COG1609 Transcriptional regulators Length = 336 Score = 180 bits (456), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 107/309 (34%), Positives = 171/309 (55%), Gaps = 4/309 (1%) Query: 4 ATIGDVAARAGVSKSTVSQFLNKRYQHMGQETRIKIEEAIEALDYRPNVLARGLKQKRTG 63 ATI DVA AGVS +TVS +NK + + + T+ K+ EA++ L+Y P+ +AR LK T Sbjct: 2 ATIKDVARLAGVSTTTVSHVINKT-RFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTR 60 Query: 64 AVGVIVANIMHRLSTEICRGIEDYCQEQNVNVILCNSDEDGEKEKKYAEMLQAKQVDGII 123 +G++V + +E+ G+E YC Q +ILCN+ EK++ Y ML K+VDGI+ Sbjct: 61 TIGMLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDGIL 120 Query: 124 LLPTGKNGALYESL-AGQGYPILFMDRRVDNVKADTIVVNNREAVTQAVKHLASLGHRSI 182 ++ + L + L A + P + MD + AD I+ N+ E A K+L GH I Sbjct: 121 VMCSDLTQELQDMLDAHKDIPKVVMDWGPETSHADKIIDNSEEGGYLATKYLTDRGHTEI 180 Query: 183 ALATGPLTISTRTERTEGFRTAMSMLGLDYGSCNII--NVEISSLKDRLRKRFEGQEPPT 240 A +G + ER +GFR AM+ L I+ N E + K + PT Sbjct: 181 ACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWILEGNFECDTAVLAADKIIAMDKRPT 240 Query: 241 ALIAGNDLVLLEALAFVKEQGLRVPEDLALVAFDNIPFAHLLTPTLTTINQPSLEMGRKA 300 A+ ND + L ++ ++++G+R+PED++++ +DNI A +P LTT++QP +G+ A Sbjct: 241 AVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKRRVGKNA 300 Query: 301 AERLITRIR 309 E L+ RI+ Sbjct: 301 FEILLERIK 309 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.368 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,792,177 Number of extensions: 914472 Number of successful extensions: 3737 Number of sequences better than 1.0e-05: 171 Number of HSP's gapped: 3371 Number of HSP's successfully gapped: 171 Length of query: 335 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 228 Effective length of database: 26,037,693 Effective search space: 5936594004 Effective search space used: 5936594004 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)