BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0574.0010.p (243 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR2233 [T] COG0639 Diadenosine tetraphosphatase and related seri... 162 5e-40 BH1859 [T] COG0639 Diadenosine tetraphosphatase and related seri... 108 1e-23 PAB1999 [T] COG0639 Diadenosine tetraphosphatase and related ser... 106 3e-23 PH1616 [T] COG0639 Diadenosine tetraphosphatase and related seri... 106 3e-23 MA4202 [T] COG0639 Diadenosine tetraphosphatase and related seri... 96 6e-20 >DR2233 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 162 bits (410), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 11/239 (4%), Positives = 39/239 (16%), Gaps = 5/239 (2%) Query: 4 IAIISDIHGNTTALETVLADIQQRRISRIFCLGDLVGKGPNSDWTVDLIREHCEKVVRGN 63 + + + + + +++ + + + + Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 64 WDEFIAGDSELEVIKWHQALLGKERLAYLSGLPFSIEFWMSGRYIRLFHASPRSVNERVQ 123 + + + G+ L + R + + Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 124 PWDDLELRVSLFEPSELCGSQLPADVAGYGDIHGAYLQHLAGKTLFNAGSVGNPLDLTQA 183 + + +L S + A L V N Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVM 187 Query: 184 SYVIVEGNYGSGDPAP-LNIQFVRVPYDIERAVQQAVDSQMPHLEPYIKELRTAEYRGK 241 Y+ + P + + + Sbjct: 188 RYLHLADK----HDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLT 242 >BH1859 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 18/235 (7%), Positives = 34/235 (14%), Gaps = 25/235 (10%) Query: 5 AIISDIHGNTTALETVLADIQQRRISRIFCLGDLVGKGPNSDWTVDLIREHCEKVVRGNW 64 I + L ++ + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 65 DEFI--------AGDSELEVIK----WHQALLGKERLAYLSGLPFSIEFWMSGRY-IRLF 111 G E +I K + +I + Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 112 HASPRSVNERVQPWDDLELRVSLFEPSELCGSQLPADVAGYGDIHGAYLQHLAGKTLFNA 171 Q + F + V+ + AGK + Sbjct: 124 DYLDLYQVHWPQR------PTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIG 177 Query: 172 GSVGNPLD-LTQASYVIVEGNYGSGDPAPLNIQFVRVPYDIERAVQQAVDSQMPH 225 S + + + V A SQ Sbjct: 178 VSNETAFGVMRYLHLADKH---DLPRIVTIQNP--YSLLNRSFEVGLAEVSQYEG 227 >PAB1999 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 106 bits (265), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 14/236 (5%), Positives = 31/236 (13%), Gaps = 30/236 (12%) Query: 4 IAIISDIHGNTTALETVLADIQQRRISRIFCLGDLVGKGPNSDWTVDLIREHCEK----V 59 I S + + D + V + + Sbjct: 6 IPHSSLEVSTLGLGTMTFGEQNS--EADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 60 VRGNWDEFIAGDSEL-------EVIKWHQALLGKERLAYLSGLPFSIEFWMSGRYIRLFH 112 + + + K + +I + RL Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 113 ASPRS-VNERVQPWDDLELRVSLFEPSELCGSQLPADVAGYGDIHGAYLQHLAGKTLFNA 171 Q A D A ++ + Sbjct: 124 DYLDLYQVHWPQRP----TNCFGKLG---YSWTDSAPAVSLLDTLDALAEYQRAGKIRYI 176 Query: 172 GSVGNPLDLT-QASYVIVEGNYGSGDPAPLNIQFVRVPYDIERAVQQAVDSQMPHL 226 G + ++ V Sbjct: 177 GVSNETAFGVMRYLHLAD---KHDL-----PRIVTIQNPYSLLNRSFEVGLAEVSQ 224 >PH1616 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 106 bits (264), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 14/241 (5%), Positives = 31/241 (12%), Gaps = 34/241 (14%) Query: 4 IAIISDIHGNTTALETVLADIQQRRISRIFCLGDLVGKGPNSDWTVDLIREHCEK----V 59 I S + + D + V + + Sbjct: 6 IPHSSLEVSTLGLGTMTFGEQNS--EADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 60 VRGNWDEFIAGDSEL-------EVIKWHQALLGKERLAYLSGLPFSIEFWMSGRYIRLFH 112 + + + K + +I + RL Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 113 ASPRS-VNERVQPWDDLELRVSLFEPSEL--CGSQLPADVAGYGDIHGAYLQHLAGKTLF 169 Q A D A ++ + Sbjct: 124 DYLDLYQVHWPQRP---------TNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIR 174 Query: 170 NAGSVGNPLDLT-QASYVIVEGNYGSGDPAPLNIQFVRVPYDIERAVQQAVDSQMPHLEP 228 G + ++ V Sbjct: 175 YIGVSNETAFGVMRYLHLAD---KHDL-----PRIVTIQNPYSLLNRSFEVGLAEVSQYE 226 Query: 229 Y 229 Sbjct: 227 G 227 >MA4202 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 95.9 bits (237), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 7/235 (2%), Positives = 36/235 (15%), Gaps = 29/235 (12%) Query: 4 IAIISDIHGNTTALETVLADIQQRRISRIFCLGDLVGKGPNSDWTVDLIREHCEKVVRGN 63 I + L + ++LI V Sbjct: 3 YHRIPHSSLEVSTLGLGT----MTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 64 WDEFIAGDSELEVIKWHQAL-----------LGKERLAYLSGLPFSIEFWMSGRYIRLFH 112 + ++ + +++ + Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 113 ASPRSVNERVQP-WDDLELRVSLFEPSELCGSQLPADVAGYGDIHGAYLQHLAGKTLFNA 171 ++ + + + + Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGY----SWTDSAPAVSLLDTLDALAEYQRAGKIR 174 Query: 172 GSVGNPLD-LTQASYVIVEGNYGSGDPAPLNIQFVRVPYDIERAVQQAVDSQMPH 225 + Y+ + + + V + + ++ + + Sbjct: 175 YIGVSNETAFGVMRYLHLADKHD-------LPRIVTIQNPYS-LLNRSFEVGLAE 221 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.138 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,656,181 Number of extensions: 864532 Number of successful extensions: 1330 Number of sequences better than 1.0e-05: 14 Number of HSP's gapped: 1315 Number of HSP's successfully gapped: 14 Length of query: 243 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 140 Effective length of database: 26,499,029 Effective search space: 3709864060 Effective search space used: 3709864060 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)