BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0571.0020.p (548 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1123 [T] COG4753 Response regulator containing CheY-like recei... 174 2e-43 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 156 7e-38 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 137 3e-32 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 110 5e-24 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 108 3e-23 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 131/541 (24%), Positives = 257/541 (47%), Gaps = 23/541 (4%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M +VI+DDE V+ GL+ + W G E +G A +G GL++++ P IVLTD+ MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 M G+ M +R ++V +SG+++ E+ R A+Q++ DYL KP + +V+ +V Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLLSAS 180 L+ + R++ ++E+ K+ + PL+ ++ S+++ R+ I E EFL Sbjct: 121 NKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPE--EFLAKITKWKD 178 Query: 181 DYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGILL 240 PQ + + D L Y+V +I+E+++ I F Y+ + Sbjct: 179 QQHIACSLTYDGPQNKELKP-ADWYLFRYSVHKMIREVLNG--YPIDF-----RYLEMDA 230 Query: 241 TRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSYK 300 R L+ + + + + + T+ G +L S+ Sbjct: 231 YRSALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFH 290 Query: 301 QARGAADQKWYLGKNRILSMDKLESAEHLRYRYEAEWSERVLTALRSGDRERTLSELEQI 360 +A Q + LG + R + E S+++ A+R D R LE+ Sbjct: 291 EA-CMESQSFPLGN---------PYEDGTRATFPMESSQKLYDAIRYADATRAKEVLEEA 340 Query: 361 FARL-EQNRGQGSRYAQNVSLHLILQSGQVMLELNGMSEEWEQKEMEAWKQVMRQETIHD 419 L E Y + + I+ + ++ + +E ++ + + + +Q + Sbjct: 341 VGVLGEVPYSTLVGYKVGIEIWTIITYS--LYDIGILIQEMFDEDFDLAQHLTKQGNWQE 398 Query: 420 LLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSENLSAADIAEGVYLSPTYVR 479 +++ ++ +C + + + K ++IE+V + I + +EN++ DIA+ +Y+S Y+ Sbjct: 399 WIRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRNYLG 458 Query: 480 LLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLFKKITGCT 539 +FK+ GE+ Y+T++R+E+AK ++++ +YEV VGY +P++F+ +FKK TG T Sbjct: 459 QIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYT 518 Query: 540 P 540 P Sbjct: 519 P 519 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 156 bits (395), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 137/559 (24%), Positives = 257/559 (45%), Gaps = 54/559 (9%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M ++IVDDE GL+ ++ I ++G A +G +E +PD+++ D++MP Sbjct: 1 MINVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 +DG++ E++ LP T+ + +S + EY R ++ +YLLKP ++++ + + ++ Sbjct: 60 VDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIV 119 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLLSAS 180 G ++ E++ ++Q +L Q ++ +L ++ D I E +E+ + Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDY---EWMEWNEWLRTEQE 176 Query: 181 DYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGILL 240 Y ++ T +Q I++ I Q+ T G ++ IL+ Sbjct: 177 GYAVVFSFHQQGKEIRKTEKQQWHAR--------IKKEIGLQLPKSTVGPFIGHHLPILM 228 Query: 241 TRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSYK 300 + E+G ++ L ++ ++ V GVG G+ L SY+ Sbjct: 229 LTENENG-----MTKQEREQVVIQLLHKVKQAVQ---PAKVKTGVG-GIYRLHFFSTSYR 279 Query: 301 QARGAAD--------QKWYLGKNRILSMDKLESAEHLRYRYEAEWSERVLTALRSGDRER 352 +A A D ++ KN + D+ + E +++ A++SGD E+ Sbjct: 280 EALLALDIIYDHKQASYYFYDKNVKIRADE---------QLPIERENKLIEAIKSGDGEK 330 Query: 353 TLSELE---QIFARLEQNRGQGSR-YAQNVSLHLILQSGQVMLELNGMSEEWEQKEMEAW 408 L + Q R ++ R Y Q L +IL G++ LN M WE + Sbjct: 331 ALQAFDHYVQAILRCSKHPLHDMRKYLQQ--LFIIL--GRL---LNEMGLHWETAQ---- 379 Query: 409 KQVMRQETIHDLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSENLSAADIA 468 R T+H + ++ + + + + R+ ++ R + + E L+ D+A Sbjct: 380 -DFARFSTVHQVTEHGKSEILHIVRTLQEWRTTDEQSLMLLARDYVHDHFREPLTLDDLA 438 Query: 469 EGVYLSPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHF 528 + + LSP YV LFK+ T EY+T++R+E AK LL Q L E+ Y +GY DP++F Sbjct: 439 KHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYF 498 Query: 529 SKLFKKITGCTPSAYREQL 547 S++FKK+TG +PS YR+ + Sbjct: 499 SRVFKKLTGKSPSDYRKSI 517 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 137 bits (346), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 145/565 (25%), Positives = 254/565 (44%), Gaps = 87/565 (15%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M ++IVDDE V GL++ + W G +I TA +G G + L PD+++ D++MP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 +DG+ + +RA + +SGH+D Y + AL DYLLKP+ EL + KV Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 121 GALDAEARERS---RVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLL 177 G + + RV+E Q ++ L L E LS I I ++ F Sbjct: 121 GRITRHHQVHELVERVQEKQVEMV--LTELLEGTPLSEIP-------IGKEHNFF----- 166 Query: 178 SASDYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRG--ITFEKQPGEY 235 A+DY QV + QD+ + ++ LI++Q G I F EY Sbjct: 167 -ATDY-----------QVALVENRQDR------LTKQLKRLIEEQEEGYVIPFP----EY 204 Query: 236 VGILLTRQLEDGDXXXXXXXXXXXXXLLLLAESIRDN----LRQWLKLS-VTIGVGEGVS 290 + I+ + L + +D+ +WL+ + G V Sbjct: 205 IVIVCKNRF--------------------LQKRGKDHRYHLFAKWLEEEELHACAGSKVV 244 Query: 291 SLPELPLSYKQARGAADQKWYLGKNRILSMDKL---ESAEHLRYRYEAEWSERVLTALRS 347 +L ++ SY+ A+ ++K+++ K R+ + D+L E + E+ +++R+ ++ Sbjct: 245 NLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRSKPEAPEFSLES-YADRLYYSIDI 303 Query: 348 GDRERTLSELEQ----IFARLEQNRGQGSRYAQNVS--LHLILQSGQVMLELNGMSEEWE 401 G+ E ++ +E+ + L++ + Q S LH +++S M E Sbjct: 304 GNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQLYSNILHQLVRSHP------NMEGVLE 357 Query: 402 QKEMEAWKQVMRQETIHDLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSEN 461 M A + + E + ++ + L+ V D +G+ ++ ++ LI + Y++N Sbjct: 358 PLVMNAG-DIYQFEHLPGIMAFLTKQLKYVID---CMDNGQPDLLLRKMIALIHKDYAKN 413 Query: 462 LSAADIAEGVYLSPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVG 521 L +A + Y+ LFK TGE YL KVRIE K LL+ K+YEV +G Sbjct: 414 LRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLLQKGY-KVYEVAEKIG 472 Query: 522 YTDPSHFSKLFKKITGCTPSAYREQ 546 Y + +F + FKK G +PS +R++ Sbjct: 473 YANVDYFHRKFKKYVGVSPSTFRKR 497 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 110 bits (276), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 50/132 (37%), Positives = 84/132 (63%), Gaps = 1/132 (0%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M +++ DDE V +GL+S ++W G E+ AD+G+ ++++ +KPD+V+TD++MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MDGIRMAAEVRAVLPF-TKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKV 119 DG+++ +V L F TK + ISG+ND Y + A++ AVD++LKPI + EL + + K+ Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 TGALDAEARERS 131 LD E S Sbjct: 121 AATLDQEKATNS 132 Score = 99.4 bits (246), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 72/294 (24%), Positives = 135/294 (45%), Gaps = 24/294 (8%) Query: 265 LAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSYKQARGAADQKWYLGKNRILSMDKLE 324 LAE +R +++ + + +T+ VG L + SY+ A + K+ + + ++ E Sbjct: 243 LAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEKNVFIHEQTE 302 Query: 325 SAEHLRYRYEAEWSERVLTALRSGDRERTLSELEQIFARLEQNRGQGS--RYAQNVSLHL 382 S + ++ + + +R ++ +++IF+ + + S + + N +H Sbjct: 303 SVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEFQTKKFVPSAVKTSVNRCVHK 362 Query: 383 ILQSGQVM-------LELNGMSEEWEQKEM--EAWKQVMRQETIHDLLQYTAAYLQEVCD 433 ++Q+ Q M + M+ WE + + KQV +T L+ Sbjct: 363 VMQTVQAMEGDTGKIISAQAMTN-WESYNLTFDQLKQV-----------FTKFVLEAAVI 410 Query: 434 YSRLKRSGKASEVIERVRLLIGQRYSENLSAADIAEGVYLSPTYVRLLFKQETGETLFEY 493 L++ S+ I +V+ I Y EN+S IA Y++P Y+ LFK+ G EY Sbjct: 411 IQELRKENMKSD-IYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEY 469 Query: 494 LTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLFKKITGCTPSAYREQL 547 L K+R+ +AK LL+ ++YEV VG+ +F F+KI TP+ YR +L Sbjct: 470 LLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRNKL 523 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 108 bits (269), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 51/127 (40%), Positives = 84/127 (66%) Query: 3 TLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPAMD 62 T++IV+DE V GL V+ A +E+IG A++G E+I+ PDI+LTD+ MP ++ Sbjct: 4 TILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHLN 63 Query: 63 GIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVTGA 122 GI++A+ VR P +VF++G++D +Y SA+++ DYLLKP R+++ ++GK+ Sbjct: 64 GIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQK 123 Query: 123 LDAEARE 129 LD E +E Sbjct: 124 LDKEEKE 130 Score = 57.8 bits (138), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 31/84 (36%), Positives = 50/84 (59%) Query: 462 LSAADIAEGVYLSPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVG 521 S +A + SPTY+ L K+E G +YL + R++QAK LL K+YE+ VG Sbjct: 158 FSLKSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVG 217 Query: 522 YTDPSHFSKLFKKITGCTPSAYRE 545 + D ++F++ FK+I G TP +++ Sbjct: 218 FEDMNYFTQRFKQIAGVTPRQFKK 241 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,790,124 Number of extensions: 1409525 Number of successful extensions: 7371 Number of sequences better than 1.0e-05: 328 Number of HSP's gapped: 7522 Number of HSP's successfully gapped: 339 Length of query: 548 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 437 Effective length of database: 25,576,357 Effective search space: 11176868009 Effective search space used: 11176868009 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)