BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0567.0047.p (311 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0819 [T] COG0642 Signal transduction histidine kinase 290 1e-78 BS_resE_4 [T] COG0642 Signal transduction histidine kinase 137 3e-32 TM1654_2 [T] COG0642 Signal transduction histidine kinase 128 1e-29 lin2727 [T] COG0642 Signal transduction histidine kinase 124 3e-28 SA1515 [T] COG0642 Signal transduction histidine kinase 122 8e-28 >BH0819 [T] COG0642 Signal transduction histidine kinase Length = 309 Score = 290 bits (743), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 140/286 (48%), Positives = 206/286 (72%), Gaps = 2/286 (0%) Query: 25 EHSRRLEYIHTKLTDIMDRDSHERLLLFNSDPHLQKLLTDLNRLLDVNHRGAVELAKLEK 84 E +++L Y+ KL +I S E +++F D L++LL +N L++ +++ + E Sbjct: 25 ERNKQLAYVTHKLDEIRTSQSAETVMVFTGDEQLRELLRAINDLIEEHNQVTATYQRTEL 84 Query: 85 SMRSMLANISHDLKTPLTVVLGYIETVLQDQTMPMEEQEKILRMIHAKAEEVIRLMNSFF 144 SMR MLANISHDLKTPLTV+ GY+ET+L + + + L + K E+I L+N FF Sbjct: 85 SMRKMLANISHDLKTPLTVIHGYVETILAGKGSANDRER--LEKVQTKTIEIIELINKFF 142 Query: 145 DLAKLESGDKDIPLSRVELGEVCRRNILSFYEILNAKGSEVDIELPDEALYIMGNEEALD 204 DLAKLE+GD+++ L +V + E+C+ ILS+++++ + +V+IE+P + Y++ +E+ALD Sbjct: 143 DLAKLEAGDQNLTLKKVAVNELCKNRILSYFDLIQNEKLQVEIEIPSQPFYVLADEKALD 202 Query: 205 RVLSNLLSNAIKYGDAGGVLGLRLYSDGDQVCIEVWDRGKGITEGDQDKVFERLYTLEDS 264 R+L NL+SNAI+YG G ++GLRLY D V IEVWDRGKGI++ D++KVFERLYTLEDS Sbjct: 203 RILDNLISNAIRYGKDGKMVGLRLYHDDAYVSIEVWDRGKGISDKDREKVFERLYTLEDS 262 Query: 265 RNRDYQGSGLGLTITKRLTEQMNGSITLRSKPHVKTAFTLSFRRQT 310 RN+ YQGSGLGLTITKRLTE++NG I L S+P+ +T+F + +R T Sbjct: 263 RNKQYQGSGLGLTITKRLTERLNGHIHLESRPYDRTSFIVKLKRIT 308 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Length = 269 Score = 137 bits (344), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 79/240 (32%), Positives = 137/240 (57%), Gaps = 11/240 (4%) Query: 74 RGAV-------ELAKLEKSMRSMLANISHDLKTPLTVVLGYIETVLQDQTMPMEEQEKIL 126 RGAV E +L+K +AN+SH+L+TP++++ GY E ++ D E++++I Sbjct: 26 RGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIA 85 Query: 127 RMIHAKAEEVIRLMNSFFDLAKLESGDKDIPLSRVELGEVCRRNILSFYEILNAKGSEV- 185 ++I+ ++ + RL+N DLA++ESG + ++ + E + I F + K + Sbjct: 86 QIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALD 145 Query: 186 -DIELPDEALYIMGNEEALDRVLSNLLSNAIKYGDAGGVLGLRLYSDGDQVCIEVWDRGK 244 DI L +E M +E+ +++V +NL+ NA+++ AGG + + ++S D + I++ D G Sbjct: 146 HDISLTEEEF--MFDEDKMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGS 203 Query: 245 GITEGDQDKVFERLYTLEDSRNRDYQGSGLGLTITKRLTEQMNGSITLRSKPHVKTAFTL 304 GI E D +FER Y + +R R G+GLGL I K + E NGSIT+ S+ T F+ Sbjct: 204 GIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFSF 263 >TM1654_2 [T] COG0642 Signal transduction histidine kinase Length = 272 Score = 128 bits (322), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 77/221 (34%), Positives = 128/221 (57%), Gaps = 10/221 (4%) Query: 81 KLEKSMRSMLANISHDLKTPLTVVLGYIETVLQDQTMPMEEQEKILRMIHAKAEEVIRLM 140 KL++ R +A +SH+L+TPLT + GY ET+L+D E ++ L++I ++ + RL+ Sbjct: 41 KLDEMRREFIATVSHELRTPLTSIHGYAETLLEDDLENKELVKRFLKIIEEESARMTRLI 100 Query: 141 NSFFDLAKLESGDKDIPLSRVELGEVCRRNILSFYEILN--AKGSEVDIELPDEALYIMG 198 N DL K+E + + + V+L EV I Y I+ A+ +EVD+ + E + + G Sbjct: 101 NDLLDLEKIEESEANFEMKDVDLCEV----IEYVYRIIQPIAEENEVDLIVECEDVVVRG 156 Query: 199 NEEALDRVLSNLLSNAIKYGD----AGGVLGLRLYSDGDQVCIEVWDRGKGITEGDQDKV 254 N+E L ++L NL+ NA+KY + +R Y D V +EV D G GI + Q ++ Sbjct: 157 NKERLIQMLLNLVDNAVKYTSLKEKGEKKVWVRAYDTPDWVVVEVEDTGPGIPKEAQSRI 216 Query: 255 FERLYTLEDSRNRDYQGSGLGLTITKRLTEQMNGSITLRSK 295 FE+ Y ++ +R+R G+GLGLTI K + ++ G I + S+ Sbjct: 217 FEKFYRVDKARSRKMGGTGLGLTIVKTIVDKHGGKIEVESE 257 >lin2727 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 124 bits (310), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 0/242 (0%), Positives = 0/242 (0%), Gaps = 9/242 (3%) Query: 64 DLNRLLDVNHRGAVELAKLEKSMRSMLANISHDLKTPLTVVLGYIETVLQDQTMPMEEQE 123 Sbjct: 217 - 275 Query: 124 KILRMIHAKAEEVIRLMNSFFDLAKLESGDKDIPLSR---VELGEVCRRNILSFYEILNA 180 Sbjct: 276 --- 332 Query: 181 KGSEVDIELPDEALYIMGNEEALDRVLSNLLSNAIKYGDAGGVLGLRLYSDGDQVCIEVW 240 Sbjct: 333 -- 390 Query: 241 DRGKGITEGDQDKVFERLYTLEDSRNRDYQGSGLGLTITKRLTEQMNGSITLRSKPHVKT 300 Sbjct: 391 450 Query: 301 AF 302 Sbjct: 451 452 >SA1515 [T] COG0642 Signal transduction histidine kinase Length = 554 Score = 122 bits (305), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 131/250 (52%), Gaps = 3/250 (1%) Query: 46 HERLLLFNSDPHLQKLLTDLNRLLDVNHRGAVELAKLEKSMRSMLANISHDLKTPLTVVL 105 H + + P L + L +L V H L +LE R +AN+SH+LKTP+T + Sbjct: 292 HAKYFDISCVPILTRSQKSLQGILVVMH-DITNLKQLENLRREFVANVSHELKTPITSIK 350 Query: 106 GYIETVLQDQTMPMEEQEKILRMIHAKAEEVIRLMNSFFDLAKLESGDKDIPLSRVELGE 165 G+ ET++ E + L +I ++ + L+ DL+ +E ++ + L + Sbjct: 351 GFAETLIDGAKNDAESLDMFLNIILKESNRIESLVTDLLDLSHIEQ-HTELDTDYMNLSD 409 Query: 166 VCRRNILSFYEILNAKGSEVDIELPDEALYIMGNEEALDRVLSNLLSNAIKYGDAGGVLG 225 + RR I + N K + ++ + + + E + +V++NLL+NAI Y G + Sbjct: 410 LTRRIIDNMMTQANQKNISIHTDIEKDVI-VKAQESKIAQVITNLLTNAINYSYEDGDIN 468 Query: 226 LRLYSDGDQVCIEVWDRGKGITEGDQDKVFERLYTLEDSRNRDYQGSGLGLTITKRLTEQ 285 +R+Y D +V EV D G GI DQ ++FER Y ++ +R+RD G+GLGL+ITK + E Sbjct: 469 VRVYRDDFRVIFEVQDFGIGIKLEDQQRIFERFYRVDKARSRDSGGTGLGLSITKHIVEA 528 Query: 286 MNGSITLRSK 295 G+I + S+ Sbjct: 529 HQGNIEVNSQ 538 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,149,895 Number of extensions: 908433 Number of successful extensions: 3914 Number of sequences better than 1.0e-05: 263 Number of HSP's gapped: 3567 Number of HSP's successfully gapped: 263 Length of query: 311 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 205 Effective length of database: 26,153,027 Effective search space: 5361370535 Effective search space used: 5361370535 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)