BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0567.0004.p (341 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ML2352 [V] COG1131 ABC-type multidrug transport system, ATPase c... 243 3e-64 SSO2137 [V] COG1131 ABC-type multidrug transport system, ATPase ... 233 4e-61 PH0913 [V] COG1131 ABC-type multidrug transport system, ATPase c... 231 2e-60 STM1403 [R] COG0457 FOG: TPR repeat 228 1e-59 TM1403 [V] COG1131 ABC-type multidrug transport system, ATPase c... 228 1e-59 >ML2352 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 311 Score = 243 bits (620), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 0/315 (0%), Positives = 0/315 (0%), Gaps = 9/315 (2%) Query: 11 SKDWAIEAHGLVKVFGDNR--AVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPD 68 + L + + + + + L + + + Sbjct: 3 RNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRIVA 62 Query: 69 GGSAKVFGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXX 128 V + + + + + +S+ N+ Sbjct: 63 YMKLDVHDQETKIQDPKDNKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKAL 122 Query: 129 XXXXXFGLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWET 188 +A + + + G + Q+ + Sbjct: 123 GNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKLSGIEKATYGGANTAKLFQIAQG 182 Query: 189 IRRLIQSGSTVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQN 248 IR + + +L+ ++ + I + + L+ Sbjct: 183 IRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAWVG 242 Query: 249 MRDIGIARQTVERML--RVQTSISAEAAKITAPLGNVDRVADLLIALR---EAGISLAEL 303 + I V + + ++ A + I + + Sbjct: 243 LLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAM--FAPKEFIPAIVGLMAVIGILIGSFG 300 Query: 304 SVQKPTLDEVFLSIT 318 Sbjct: 301 315 >SSO2137 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 339 Score = 233 bits (593), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 129/330 (39%), Positives = 200/330 (60%), Gaps = 5/330 (1%) Query: 6 KQPLPSKDWAIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLL 65 ++ L ++ AI+A L K FG AVD ++ +V G I+G LGPNGAGK+T I+ML T+L Sbjct: 2 RRLLKMRNVAIKAINLTKRFGKFVAVDHINFEVYEGEIFGFLGPNGAGKSTTIKMLTTVL 61 Query: 66 RPDGGSAKVFGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXX 125 +P G+A V G+DV+K+P +VRQ IGV Q + DE L+ EN+++ + Sbjct: 62 KPSEGTATVSGYDVIKQPALVRQSIGVVPQEYTADEDLTGWENMMMMAGLYGIPKRIAEE 121 Query: 126 XXXXXXXXFGLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQM 185 LT AAKR ++ +SGGMRRRL++A SLI++P ++FLDEPT GLD +TR + Sbjct: 122 RAKELLEMVELTYAAKRKVETYSGGMRRRLEIAMSLISRPRILFLDEPTLGLDAQTRAAI 181 Query: 186 WETIRRLIQSGS-TVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQL 244 W+ I +L + T+ +TT YLEEAD DRIA+ID G ++A G+ ELK VG + L Sbjct: 182 WQYIMKLKEEYKMTIFVTTHYLEEADMYGDRIAIIDKGKILAIGSPKELKEKVGGDVVSL 241 Query: 245 RVQNMR-DIGIARQTVERMLRVQTSISAEAAKITAPLGNVDRVADLLIALREAGISLAEL 303 + N I I + + +L V+ +++ +I G ++ ++L +L + GI ++ + Sbjct: 242 QTSNDELAIKIISSSKDGILDVRK--ASDGIRIKVRNGE-EKAPEILESLVKNGIKVSRM 298 Query: 304 SVQKPTLDEVFLSITGHGVEEKSAPASAEF 333 S+ +PT+DEV++ TG + ++ A A F Sbjct: 299 SITEPTMDEVYMEFTGKSLRDEEASAQEMF 328 >PH0913 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 324 Score = 231 bits (588), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 131/324 (40%), Positives = 182/324 (56%), Gaps = 28/324 (8%) Query: 15 AIEAHGLVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKV 74 AI LVK +GD AV G+ +V G I+ LGPNGAGKTT + ML TLL+P G A V Sbjct: 6 AIIVENLVKKYGDFEAVRGISFKVRRGEIFAFLGPNGAGKTTTVHMLTTLLKPTSGRAIV 65 Query: 75 FGHDVVKEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXF 134 GHDVVKE + VR+ IGV Q SVD L+A EN+ I Sbjct: 66 AGHDVVKESREVRKKIGVVFQDPSVDRELTAWENMYIHGRIYGLKGQELKKKIEELLKFV 125 Query: 135 GLTEAAKRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQ 194 L E R +K FSGGM+RRL++A +LI +P ++FLDEPT GLDP+TR +WE I+ + + Sbjct: 126 ELWEFKDRQVKYFSGGMQRRLEIARALIHEPEVLFLDEPTIGLDPQTRAHIWEYIKTMKE 185 Query: 195 SGS-TVLLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDIG 253 T+ LTT Y++EA+QLADRIA+IDHG ++AEGT +ELK VG + ++ + Sbjct: 186 EHDMTIFLTTHYMDEAEQLADRIAIIDHGKIIAEGTAEELKKLVGNDIIYVKFEK----- 240 Query: 254 IARQTVERMLRVQTSISAEAAKITAPLGN------VDRVADLLIAL----REAGISLAEL 303 T I AE + L N V A+ L + RE + + E+ Sbjct: 241 ------------PTCIQAEFIRGCKVLNNGRVALEVKNAAEALPLVFEKAREMELKILEV 288 Query: 304 SVQKPTLDEVFLSITGHGVEEKSA 327 + +PTL++VFL +TG + ++++ Sbjct: 289 TYHRPTLNDVFLHLTGREIRDEAS 312 >STM1403 [R] COG0457 FOG: TPR repeat Length = 673 Score = 228 bits (581), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 22/313 (7%), Positives = 63/313 (20%), Gaps = 11/313 (3%) Query: 21 LVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKVFGHDVV 80 V+ V T I + G R +A + + + ++ Sbjct: 10 AVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQ 69 Query: 81 KEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXFGLTEAA 140 + + + ++ + + + + + + Sbjct: 70 TLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDK 129 Query: 141 KRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQSGS-TV 199 + S + DL A I + + + L + Sbjct: 130 VLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILL 189 Query: 200 LLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDI--GIARQ 257 E + + + + T V + Sbjct: 190 PTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYS 249 Query: 258 TVERMLRVQTSISAEAAKITAPLGNVDRVADLLIALREAGISLAELSVQKPTLDEVFLSI 317 + +S + + ++ R +G L ++ VF Sbjct: 250 WRGARPQNLVLLSQDFPALKVI-----KLEQN---YRSSGRILKAANILIANNPHVFEKR 301 Query: 318 TGHGVEEKSAPAS 330 + + Sbjct: 302 LFSELGYGAELKV 314 >TM1403 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 327 Score = 228 bits (581), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 128/313 (40%), Positives = 181/313 (57%), Gaps = 11/313 (3%) Query: 21 LVKVFGDNRAVDGVDLQVATGSIYGVLGPNGAGKTTAIRMLATLLRPDGGSAKVFGHDVV 80 LVK FGD AV GV V G I+ LGPNGAGKTT I ML TLL+P G A V GHDV+ Sbjct: 10 LVKKFGDFEAVKGVSFSVKKGEIFAFLGPNGAGKTTTIHMLTTLLKPTSGKAWVAGHDVL 69 Query: 81 KEPQIVRQLIGVTGQYASVDESLSATENLVIFSXXXXXXXXXXXXXXXXXXXXFGLTEAA 140 KEP+ VR+ IG+ Q S+D L+A EN+ I L E Sbjct: 70 KEPREVRRKIGIVFQDQSLDRELTAYENMYIHGKIYGYGGEKLKKRILELLEFVELLEFK 129 Query: 141 KRPLKNFSGGMRRRLDLAASLIAQPPLIFLDEPTTGLDPRTRNQMWETIRRLIQSGS-TV 199 +P+K FSGGM RRL++A SLI +P ++FLDEPT GLDP TR MWE I ++ + + T+ Sbjct: 130 DKPVKTFSGGMARRLEIARSLIHEPEVLFLDEPTIGLDPHTRAHMWEYISKMKKEHNMTI 189 Query: 200 LLTTQYLEEADQLADRIAVIDHGHVVAEGTVDELKSSVGTSSLQLRVQNMRDI--GIARQ 257 LTT Y++EA+QLADR+A+IDHG ++A GT ELK VG + +R + G + Sbjct: 190 FLTTHYMDEAEQLADRVAIIDHGKIIALGTPTELKRMVGKEIIYVRFSEAVECLEGDFIE 249 Query: 258 TVERMLRVQTSISAEAAKITAPLGNVDRVADLLIALREAGISLAELSVQKPTLDEVFLSI 317 + ++ + ++ E + P ++ +L ++ G+ + E++ KPTL++VFL + Sbjct: 250 SCRKLPDGRLELNVEDSGRAIP-----KIFEL---AQQKGLKIEEITYHKPTLNDVFLHL 301 Query: 318 TGHGVEEKSAPAS 330 TG + E+ S Sbjct: 302 TGRELREEGPENS 314 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.132 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,112,289 Number of extensions: 845580 Number of successful extensions: 10391 Number of sequences better than 1.0e-05: 1754 Number of HSP's gapped: 8757 Number of HSP's successfully gapped: 1963 Length of query: 341 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 234 Effective length of database: 26,037,693 Effective search space: 6092820162 Effective search space used: 6092820162 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)