BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0566.0030.p (305 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0464 [K] COG2378 Predicted transcriptional regulator 149 6e-36 lin0395 [K] COG2378 Predicted transcriptional regulator 126 4e-29 lin2535 [K] COG2378 Predicted transcriptional regulator 100 2e-21 BH0411 [K] COG2378 Predicted transcriptional regulator 87 4e-17 mlr3764 [K] COG2378 Predicted transcriptional regulator 73 5e-13 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 149 bits (376), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 103/320 (32%), Positives = 169/320 (52%), Gaps = 28/320 (8%) Query: 1 MKMDRLLGIVVYLLNRETVSARELAEKFEVSPRTIQRDMASISLAGIPVGSQQGLNGGYY 60 MK+DRL+ IV+ LL++E +SA+ELA++FEVS RTI RD+ +I LAG+P+ S G+ GG+ Sbjct: 1 MKVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFE 60 Query: 61 IIDSYKMNRQLLQSEDYTYI---LAALKGLLSGYDSLRAQSTVEIMTSLAPDKAALGPML 117 I+ YKM+ ++ + D + I L++L ++ G + + A + ++ S P A L Sbjct: 61 IMPDYKMDSKVFSTADLSAILMGLSSLSNMVRGDELINALAKIK---SFIPADRAKEIEL 117 Query: 118 QLNLGVLREGEGTGGN-----IALVEKAIREKIWLGFQYTDARGGVTDRGVEPLLLTYKW 172 + N + + TG N + +++ A++E L F+Y +G T R VEP L K Sbjct: 118 KANQIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYIAHQGNKTVRIVEPYQLVMKS 177 Query: 173 YAWYLFAYCCDKQDYRLFRLSRMRSVHLMSQTFTLTHKDAELLLSEHSDL----RPQTKV 228 WYL+ YC ++ D+RLFRLSRM + ++ TFTL +D + E D+ + + K+ Sbjct: 178 SHWYLYGYCQNRNDFRLFRLSRMSGLQILEDTFTL--RDFQKPQLEMEDIVAIMQIEIKI 235 Query: 229 RLACMAEHKVL----LQEAFPQAXXXXXXXXXXXMSFTVPEEEQGWFGKLLEYSQRITVL 284 R+ +VL + +P +SF E E + LL + + L Sbjct: 236 RIHQSIIDRVLDYCSYENFYPDG------EEHYIVSFPFIENEYHY-DILLSFGDKCECL 288 Query: 285 EPEELRLRMHTQAAFILEKY 304 EP +R +M + I+ Y Sbjct: 289 EPLHVREKMKRRIYDIVSIY 308 >lin0395 [K] COG2378 Predicted transcriptional regulator Length = 306 Score = 126 bits (317), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 70/210 (33%), Positives = 120/210 (57%), Gaps = 9/210 (4%) Query: 1 MKMDRLLGIVVYLLNRETVSARELAEKFEVSPRTIQRDMASISLAGIPVGSQQGLNGGYY 60 MK++RL+GI++ LL RE VSA E+A FEVS RTI RD+ ++S+A IP+ + G GG Sbjct: 1 MKIERLIGIIMLLLQRELVSASEMATMFEVSKRTIFRDIDTLSMANIPIYTIAGTKGGIG 60 Query: 61 IIDSYKMNRQLLQSEDYTYILAALKGLLSGYDSLRAQSTVEIMTSL-----APDKAALGP 115 I+ +YK++++LL ++D T I+A+L G+ S + T++ M ++ P K+++ Sbjct: 61 IMPTYKVDKKLLTADDLTAIIASLDGMEQLLSSAETKKTLQKMKNMLEHSSEPPKSSIS- 119 Query: 116 MLQLNLGVLREGEGTGGNIALVEKAIREKIWLGFQYTDARGGVTDRGVEPLLLTYKWYAW 175 L+ L + + + AI++ + Y D G T R EP L ++ +W Sbjct: 120 ---LDFSNLSMKKELNAKVESLYLAIKKHQLVELSYIDRTGNQTVRKTEPYHLLFRNRSW 176 Query: 176 YLFAYCCDKQDYRLFRLSRMRSVHLMSQTF 205 YL Y ++ D+R F++SR+ + + +TF Sbjct: 177 YLQGYSLERSDFRTFKMSRIVELKTLEETF 206 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 74/215 (34%), Positives = 111/215 (51%), Gaps = 21/215 (9%) Query: 1 MKMDRLLGIVVYLLNRETVSARELAEKFEVSPRTIQRDMASISLAGIPVGSQQGLNGGYY 60 MK++R+L I+V +L R+ V A ELAEKFEVS RTI RDM ++ AG PV + G NGG+ Sbjct: 1 MKLERILAILVMILERK-VLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFT 59 Query: 61 IIDSYKMNRQLLQSEDYTYILAALKG-----LLSGYDSLRAQSTVEIMTSLAPDK----- 110 ++D+YK+ E+ +L AL+ L ++LR + T ++ + P Sbjct: 60 MLDTYKLATFTFSEEEKRILLEALEARSEFMLNDSQETLREKIT--LLQTEKPTSNYIFF 117 Query: 111 -AALGPMLQLNLGVLREGEGTGGNIALVEKAIREKIWLGFQYTDARGGVTDRGVEPLLLT 169 +A Q+ V R+ IA ++KA K L Y G T+R + P L Sbjct: 118 DSATQHRKQIEAEVKRK-------IAYIQKAFTMKKQLDITYIAMDGTETNREISPQKLN 170 Query: 170 YKWYAWYLFAYCCDKQDYRLFRLSRMRSVHLMSQT 204 +WYL AYC + R F+L+R+ S+ S+T Sbjct: 171 LMDGSWYLEAYCHKRAAIRHFKLTRITSLKETSKT 205 >BH0411 [K] COG2378 Predicted transcriptional regulator Length = 331 Score = 86.7 bits (213), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 114/220 (51%), Gaps = 14/220 (6%) Query: 1 MKMDRLLGIVVYLLNRETVSARELAEKFEVSPRTIQRDMASISLAGIPVGSQQGLNGGYY 60 MK DRLL IV L N E ++ +L + VS RTI RDM ++S GIP+ S++G GG+ Sbjct: 1 MKADRLLEIVALLQNHEKLTTHQLVDHLHVSSRTILRDMDTLSALGIPIVSERGRAGGWK 60 Query: 61 IIDSYKMNRQLLQSEDYT--YILAALKGLLS-GYDSLRAQSTVEIMTSLAPD-KAALGPM 116 ++D ++ + + +IL + K L G + + +++SL + K A+ P Sbjct: 61 LMDHFRSQLSGMSMTELKALFILPSDKVLKDLGIPTKGRDIRLNMLSSLQGNRKHAVRPY 120 Query: 117 LQ---LNLGVLREGEGTGGNIALVEKAIREKIWLGFQYTDARGGVTDRGVEPLLLTYKWY 173 L+ ++ G + + +V++A+ E+ L Y +A+G +R + PL L K Sbjct: 121 LEKVYIDTGTWKPSKERMEEFNVVQQAVFEEKKLYIVYENAKGEQRERLISPLGLVAKGS 180 Query: 174 AWYLFAYCCDKQDYRLFRLSRMRSVHLM------SQTFTL 207 AWY+ A + D R F+LSR++ L+ +TF+L Sbjct: 181 AWYVVA-TVETGDIRNFKLSRIKDSKLVREPIVKPETFSL 219 >mlr3764 [K] COG2378 Predicted transcriptional regulator Length = 239 Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 55/209 (26%), Positives = 96/209 (45%), Gaps = 8/209 (3%) Query: 2 KMDRLLGIVVYLLNRETVSARELAEKFEVSPRTIQRDMASISLAGIPVGSQQGLNGGYYI 61 + DRL IV +L V+A++L EVS RTI RD+A + G+P+ + G+ GY + Sbjct: 3 RADRLFQIVQHLRGGRLVTAQKLGTWLEVSERTIYRDIADLQSTGVPIDGEAGV--GYMM 60 Query: 62 IDSYKMNRQLLQSEDYTYILAALKGLLSGYDSLRAQST-----VEIMTSLAPDKAALGPM 116 + + + L+ + D L A ++ + V+I L + Sbjct: 61 REGFDLP-PLMFTRDEIVALVAGARMVRAFGGAAMARAADEALVKIGAVLPDTEKDRIAR 119 Query: 117 LQLNLGVLREGEGTGGNIALVEKAIREKIWLGFQYTDARGGVTDRGVEPLLLTYKWYAWY 176 +++ + + I L+E+A+ ++ L Y D G T R + PL L + W Sbjct: 120 TEIHTPMWVVSDAAREAIDLIERAVEKRQVLTIDYCDEAGRGTARDIRPLGLWFWGKVWT 179 Query: 177 LFAYCCDKQDYRLFRLSRMRSVHLMSQTF 205 L A+C + D+R FR+ R+ SV + + F Sbjct: 180 LVAWCEMRDDFRAFRIDRIASVVIAGRIF 208 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.136 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,559,046 Number of extensions: 806060 Number of successful extensions: 3480 Number of sequences better than 1.0e-05: 13 Number of HSP's gapped: 3469 Number of HSP's successfully gapped: 13 Length of query: 305 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 199 Effective length of database: 26,153,027 Effective search space: 5204452373 Effective search space used: 5204452373 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)