BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0566.0021.p
         (444 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CAC1585 [R] COG2270 Permeases of the major facilitator superfamily    265   8e-71
CAC2743 [R] COG2270 Permeases of the major facilitator superfamily    220   5e-57

>CAC1585 [R] COG2270 Permeases of the major facilitator superfamily
          Length = 425

 Score =  265 bits (678), Expect = 8e-71,   Method: Compositional matrix adjust.
 Identities = 143/389 (36%), Positives = 223/389 (57%), Gaps = 13/389 (3%)

Query: 10  RAWLMYDWANSAYATTVLAAVLPIFYSSVA-ASGLSENTAASYLAYTHAIGMALVALVSP 68
           ++W+MYDWANSAY+T + A +LP+++ S+A  SG+S  ++ +Y  Y+++I   L+A++SP
Sbjct: 9   KSWIMYDWANSAYSTAITATILPLYFKSIALKSGVSAASSTAYWGYSNSIATLLIAILSP 68

Query: 69  LLGSISDLSGRKTSFLTAFALLGIVSTMGFALVGEGDWXXXXXXXXXXXXGFAGSLTFYD 128
           +LG+++D  G K      F +LG   T+  ++V    W            GF+GS  FYD
Sbjct: 69  ILGTMADYKGYKMKLFNVFFILGTSFTLLLSVVPTNYWLLIILFYILTSIGFSGSCIFYD 128

Query: 129 SMLPDLVPSGKRDDVSAKXXXXXXXXXXXXXXXXXXMIQQPQLLGMKDTP----AGTRLS 184
           + L D+  +   D VS+                   +I   QL   K  P       ++S
Sbjct: 129 AFLVDVSDNDNMDRVSSLGFGMGYIGSNIPFILCILIIALAQL---KIIPISFFTACKIS 185

Query: 185 FVSVGLWWLIFSIPAIRRVPNLPRQTAGLS-AGGYVRAAARRIGGSTRDIKRYPQLVRLI 243
           F    LWW IF+IP I+ V    +QT  ++      R +  R+  + +DIK++ QL   +
Sbjct: 186 FAITALWWAIFTIPMIKNV----KQTYSINIEKNPARKSFLRLKSTLKDIKKHKQLFIFL 241

Query: 244 AAFWFYNDGINTIILMATIYGTTLGIGSSDLILALLITQFVGFPSTILLGKTAERLGAKR 303
            +++FY DG+NTII MAT YG+ LGI S+ +++ LL+ QF+ FP +I+ G  A++   K 
Sbjct: 242 LSYFFYIDGVNTIITMATSYGSDLGINSTTMLVILLVMQFIAFPFSIIFGMLAKKFQGKT 301

Query: 304 MLLVSLFIYVLIVILGFGMTRAVHFYILAVMVGLVQGGSQSISRSLLSDLMPLKRTGEFF 363
           ML V + IY +I +  + +   + F+ILA++VG  QGG Q++SRS L  L+P  +  EFF
Sbjct: 302 MLYVGIVIYSIICVYSYFLRSTLDFWILAILVGTSQGGIQALSRSYLGKLVPKNKANEFF 361

Query: 364 GFVNITSKFSSIFGPFVFGLVGQLTGNPR 392
           GF NI  KFS+I GPF+ G+V Q+TGN  
Sbjct: 362 GFYNIFGKFSAILGPFMVGIVSQVTGNSN 390


>CAC2743 [R] COG2270 Permeases of the major facilitator superfamily
          Length = 429

 Score =  220 bits (560), Expect = 5e-57,   Method: Compositional matrix adjust.
 Identities = 133/392 (33%), Positives = 216/392 (55%), Gaps = 11/392 (2%)

Query: 4   MNK--SAVRAWLMYDWANSAYATTVLAAVLPIFYSSV-AASGLSENTAASYLAYTHAIGM 60
           MNK   A ++W++YD   S Y+  ++  +LPI++  V   +G SE ++ +Y  Y+++IG 
Sbjct: 1   MNKYNKAEKSWILYDCTISTYSMIIITTILPIYFRMVFKNAGGSEASSTAYWGYSNSIGR 60

Query: 61  ALVALVSPLLGSISDLSGRKTSFLTAFALLGIVSTMGFALVGEGDWXXXXXXXXXXXXGF 120
            L+AL++PLLG+I+D  G K  F   F ++GI+ T   A V    W            G 
Sbjct: 61  LLIALLAPLLGTIADYIGYKMKFFKVFCIIGIIFTALIAAVPNSAWLPLVIVFIISTIGN 120

Query: 121 AGSLTFYDSMLPDLVPSGKRDDVS--AKXXXXXXXXXXXXXXXXXXMIQQPQLLGMKDTP 178
           AGS  FYD+ L D+ P  K D +S  A                   ++ Q  ++ +    
Sbjct: 121 AGSNVFYDAFLVDITPKSKMDMLSSIAYACGYLGNILAFAVCMSIVILAQLHIIPISIMT 180

Query: 179 AGTRLSFVSVGLWWLIFSIPAIRRVPNLPRQTAGLSAGGYVRAAA-RRIGGSTRDIKRYP 237
           A  +++FV   +W  +FSIP ++ V    +Q  G+     V   + +R+G + ++I ++ 
Sbjct: 181 A-CKITFVITAIWCTMFSIPIMKNV----KQIYGIKKEHRVIVNSIKRLGSTFKNIGKHK 235

Query: 238 QLVRLIAAFWFYNDGINTIILMATIYGTTLGIGSSDLILALLITQFVGFPSTILLGKTAE 297
            LV  + +++F+ DG+NTII MAT +G  +GI S+ +++ LL TQF+ FP  I+ GK +E
Sbjct: 236 NLVIFLISYFFFIDGVNTIITMATSFGADIGINSTVMLVVLLFTQFIAFPCAIIFGKLSE 295

Query: 298 RLGAKRMLLVSLFIYVLIVILGFGMTRAVHFYILAVMVGLVQGGSQSISRSLLSDLMPLK 357
           +   K ML   + IY +I +    +   + F ILAV+VG  QGG Q++SRS    L+P +
Sbjct: 296 KFKGKTMLYAGIIIYSIICVYANFIHNILGFIILAVLVGTSQGGIQALSRSYFGKLVPKE 355

Query: 358 RTGEFFGFVNITSKFSSIFGPFVFGLVGQLTG 389
           +  EFFGF NI  +F+SI GP +  ++ Q+TG
Sbjct: 356 KNNEFFGFFNIFGRFASILGPLLVAVITQITG 387


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.324    0.139    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 26,970,890
Number of extensions: 1049046
Number of successful extensions: 3263
Number of sequences better than 1.0e-05: 6
Number of HSP's gapped: 3282
Number of HSP's successfully gapped: 6
Length of query: 444
Length of database: 38,378,431
Length adjustment: 110
Effective length of query: 334
Effective length of database: 25,691,691
Effective search space: 8581024794
Effective search space used: 8581024794
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 117 (49.7 bits)