BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0566.0005.p (381 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3958 [E] COG0019 Diaminopimelate decarboxylase 482 e-136 DR1410 [E] COG0019 Diaminopimelate decarboxylase 406 e-113 SP0920 [E] COG0019 Diaminopimelate decarboxylase 404 e-112 Cj1515c [E] COG0019 Diaminopimelate decarboxylase 367 e-101 HP0020 [E] COG0019 Diaminopimelate decarboxylase 357 2e-98 >BH3958 [E] COG0019 Diaminopimelate decarboxylase Length = 379 Score = 482 bits (1240), Expect = e-136, Method: Compositional matrix adjust. Identities = 228/379 (60%), Positives = 287/379 (75%), Gaps = 3/379 (0%) Query: 4 IDIDISTLPSPAYLVDERLLKKNLETLNYVQEKTGAKILLAQKGFSMHALYPLVGKYLHG 63 + + LP+P Y+VDE L++KN++ LN + ++TGAKI+LAQK FSM +YPL+GKYL G Sbjct: 3 VKMRFEELPTPCYVVDEALVEKNVKILNGIMKRTGAKIVLAQKAFSMSTMYPLIGKYLTG 62 Query: 64 VTSSSLFEARLGYEEMGKEVHVYAPAYMDREFDELLSYTDHIVFNSFDQWARFKNRVQSA 123 T+S L+EARLG+EEMGKE H++APAY + E DE++S DHI+FNSF Q +FK R A Sbjct: 63 TTASGLYEARLGHEEMGKENHIFAPAYREDEIDEIVSICDHIIFNSFSQLEKFKQRALDA 122 Query: 124 PKAISCGIRVNPEYS-EIEVPLYDPCYNYSRMGVTLPNFRPEELDGIDGLHFHTMCEQNS 182 + G+R+NPE S ++ +YDPC SR GV + R E LDG+ GLHFHT+C+QNS Sbjct: 123 GSKV--GLRINPECSTQVGHEIYDPCSPGSRFGVKQEDVRQELLDGVSGLHFHTLCQQNS 180 Query: 183 DTLERTLKVVEEKFGQYLHGMKWLNFGGGHHITRPDYDLETLIRCILHMKETYNVQIYLE 242 D LE TL VEEKFGQ+L M+W+NFGGGHHITR DYD+ L CI M++ Y +++YLE Sbjct: 181 DDLETTLDAVEEKFGQWLPQMEWINFGGGHHITRDDYDIPRLEACIKRMQDKYGLEVYLE 240 Query: 243 PGEAVALNTGYLVATVLDTMHNGMDIAILDTSAECHMPDVLAMPYRPGIIGAGEPGEYPY 302 PGEA+ALN GYLV TVLD NG+DIAILDTSA CHMPDVL MPYRP + G+GEPGE P+ Sbjct: 241 PGEAIALNAGYLVTTVLDLHKNGIDIAILDTSATCHMPDVLEMPYRPPLFGSGEPGEKPF 300 Query: 303 TYRLGGMTCLAGDVIGDYSFKEPLKYGDKLVFLDMAHYSMVKNHMFNGVNLPAIASYNDE 362 TYRLGG TCL GDVIGDYSF +PLK GD+LVF DMA YSMVK + FNG+ LPAIA+ + + Sbjct: 301 TYRLGGPTCLTGDVIGDYSFDQPLKSGDRLVFGDMAIYSMVKTNTFNGMPLPAIATKHQD 360 Query: 363 EGLKVIREFEYQDFSNRLS 381 +V+R+F YQDF RL+ Sbjct: 361 GDCQVVRQFGYQDFKTRLA 379 >DR1410 [E] COG0019 Diaminopimelate decarboxylase Length = 416 Score = 406 bits (1044), Expect = e-113, Method: Compositional matrix adjust. Identities = 199/392 (50%), Positives = 268/392 (68%), Gaps = 18/392 (4%) Query: 6 IDISTLPSPAYLVDERLLKKNLETLNYVQEKTGAKILLAQKGFSMHALYPLVGKY-LHGV 64 +D +PSPA+++DE L++NL +NYVQ+++GA+I++A KGFSM + +PL+ +Y + G Sbjct: 27 VDWDRIPSPAFVLDETRLRRNLTLINYVQQQSGAQIIVAFKGFSMWSTFPLLREYGITGA 86 Query: 65 TSSSLFEARLGYEEMGKEVHVYAPAYMDREFDELLSYTDHIVFNSFDQWARFKNRVQSAP 124 T+SSL EA L EEM EVHVYAPAY D +F +L DH+VFNSF QW RF+ +VQ+A Sbjct: 87 TASSLNEAILAKEEMQGEVHVYAPAYSDEDFPRILELADHLVFNSFAQWERFRPQVQAAR 146 Query: 125 ---KAISCGIRVNPEYSEIEVPLYDPCYNYSRMGVTLPNFRPEELDGIDGLHFHTMCEQN 181 + + GIR+NPEY+E+E LY+P +SR+GVT FR + LDGIDGLHFHT+CE++ Sbjct: 147 AGGRELHVGIRINPEYAEVETDLYNPAGPFSRLGVTRREFREDLLDGIDGLHFHTLCEKD 206 Query: 182 SDTLERTLKVVEEKFGQYLHGMKWLNFGGGHHITRPDYDLETLIRCILHMKETYNVQIYL 241 SDTLERTL+VVE FG++L M W+NFGGGH +TR YD+ LIR + +E + V + L Sbjct: 207 SDTLERTLEVVERNFGEFLPRMNWVNFGGGHLMTREGYDIPRLIRVVKAFREKHGVHVIL 266 Query: 242 EPGEAVALNTGYLVATVLDTMHNGMDIAILDTSAECHMPDVLAMPYRPGIIGAGEP---- 297 EPG A TG+LV++VLD +HN D A+LD S HMPDVL MPYRP I+GAG+P Sbjct: 267 EPGSAFGWQTGWLVSSVLDVVHNVKDAALLDVSVSAHMPDVLEMPYRPRILGAGDPPLDD 326 Query: 298 --------GEYPYTYRLGGMTCLAGDVIGDYSFKEPLKYGDKLVFLDMAHYSMVKNHMFN 349 YPY +GG TCLAGDV+G+Y F LK G ++VF DM HY+MVK FN Sbjct: 327 HREAQDTGSGYPYI--IGGTTCLAGDVVGEYVFPHELKVGSRVVFDDMIHYTMVKTTFFN 384 Query: 350 GVNLPAIASYNDEEGLKVIREFEYQDFSNRLS 381 GV P I + + + ++ F Y++F +LS Sbjct: 385 GVKHPDIGILHADGSYERVKTFGYEEFKAKLS 416 >SP0920 [E] COG0019 Diaminopimelate decarboxylase Length = 375 Score = 404 bits (1038), Expect = e-112, Method: Compositional matrix adjust. Identities = 196/377 (51%), Positives = 261/377 (69%), Gaps = 3/377 (0%) Query: 6 IDISTLPSPAYLVDERLLKKNLETLNYVQEKTGAKILLAQKGFSMHALYPLVGKYLHGVT 65 + + +P+PAY++D L+ N L YVQE+ G K+LLAQK +S++ YPL+ +YL G T Sbjct: 1 MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYSLYKTYPLISQYLSGTT 60 Query: 66 SSSLFEARLGYEEMGKEVHVYAPAYMDREFDELLSYTDHIVFNSFDQWARFKNRVQSAPK 125 +S L+EA+L EE EVHV+APA+ D + +ELL DHIVFNS Q + R + A Sbjct: 61 ASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVFNSERQLRKHGPRCREA-- 118 Query: 126 AISCGIRVNPEYS-EIEVPLYDPCYNYSRMGVTLPNFRPEELDGIDGLHFHTMCEQNSDT 184 +S G+R+NP+ S + + LYDPC SR GVT+ + LD +DGLHFHT+CEQ +D Sbjct: 119 GVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLLDLVDGLHFHTLCEQGADD 178 Query: 185 LERTLKVVEEKFGQYLHGMKWLNFGGGHHITRPDYDLETLIRCILHMKETYNVQIYLEPG 244 L+ TLK VEE+FG YLH +KWLN GGGHHITR YD++ LI I +++TYN++IY+EPG Sbjct: 179 LQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLLISEIKRIRKTYNLEIYIEPG 238 Query: 245 EAVALNTGYLVATVLDTMHNGMDIAILDTSAECHMPDVLAMPYRPGIIGAGEPGEYPYTY 304 EA+ALN GYL VLD + NGM+I +LD SA CHMPDVL MPYRP + E E +TY Sbjct: 239 EAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDVLEMPYRPPLRNGFESQEKAHTY 298 Query: 305 RLGGMTCLAGDVIGDYSFKEPLKYGDKLVFLDMAHYSMVKNHMFNGVNLPAIASYNDEEG 364 RL TCL GDVIGDYSF+ P++ GD+L F DMA YS VKN+ FNG+ LP++ +++ Sbjct: 299 RLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIYSFVKNNTFNGIGLPSLYLMDEQGD 358 Query: 365 LKVIREFEYQDFSNRLS 381 +++ F YQDF RLS Sbjct: 359 CSLLKAFGYQDFKGRLS 375 >Cj1515c [E] COG0019 Diaminopimelate decarboxylase Length = 382 Score = 367 bits (943), Expect = e-101, Method: Compositional matrix adjust. Identities = 180/380 (47%), Positives = 248/380 (65%), Gaps = 15/380 (3%) Query: 11 LPSPAYLVDERLLKKNLETLNYVQEKTGAKILLAQKGFSMHALYPLVGKYLHGVTSSSLF 70 + +PAY+++E L+KN E L V EK+GAK+LLA KGF+ +VG+YL G T S L+ Sbjct: 6 IQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLW 65 Query: 71 EARLGYEEMGKEVHVYAPAYMDREFDELLSYTDHIVFNSFDQWARFKNRVQSAPKAISCG 130 EA+ E M KE+H Y+PA+ + E E+ S + HIVFNS Q+ +F+ + Q S G Sbjct: 66 EAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKN----SLG 121 Query: 131 IRVNPEYSEIEVPLYDPCYNYSRMGVTLPNFRPEELDGIDGLHFHTMCEQNSDTLERTLK 190 +R N E+S LY+PC YSR+G+ +F +L I+GLHFH +CE+++ LE LK Sbjct: 122 LRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLSTIEGLHFHALCEESAGALEAVLK 181 Query: 191 VVEEKFGQYLHGMKWLNFGGGHHITRPDYDLETLIRCILHMKETYNVQIYLEPGEAVALN 250 V EEKFG+++ MKW+NFGGGHHIT+ YD+E LI + + Y VQ+YLEPGEAV Sbjct: 182 VFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKLIALCKNFSDKYGVQVYLEPGEAVGWQ 241 Query: 251 TGYLVATVLDTMHNGMDIAILDTSAECHMPDVLAMPYRPGIIGA-----------GEPGE 299 TG LVA+V+D + N IAILDTS+E HMPD + MPY ++ A + E Sbjct: 242 TGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARILATRENEKISDLKE 301 Query: 300 YPYTYRLGGMTCLAGDVIGDYSFKEPLKYGDKLVFLDMAHYSMVKNHMFNGVNLPAIASY 359 ++Y L G TCLAGDV+G+Y+F + LK GDK+VFLD HY++VKN FNG+ LP + Sbjct: 302 SEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLL 361 Query: 360 NDEEGLKVIREFEYQDFSNR 379 N + L++IREF Y+D+S R Sbjct: 362 NAKNELQMIREFSYKDYSLR 381 >HP0020 [E] COG0019 Diaminopimelate decarboxylase Length = 405 Score = 357 bits (916), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 180/401 (44%), Positives = 258/401 (64%), Gaps = 31/401 (7%) Query: 9 STLPSPAYLVDERLLKKNLETLNYVQEKTGAKILLAQKGFSMHALYPLVGKYLHGVTSSS 68 ST+P+P Y+++ L+KN + L V++++GAK+LLA KG++ + ++ + L+G +S Sbjct: 5 STIPTPCYVLESERLEKNAKILEIVRQQSGAKVLLALKGYAFWREFGILRQKLNGCCASG 64 Query: 69 LFEARLGYEEMG-----KEVHVYAPAYMDREFDELLSYTDHIVFNSFDQWARFKNRVQSA 123 L+EA+L +EE G KE+ VY+PA+ + E +L I+FNSF Q+A +K+R+ Sbjct: 65 LYEAKLAFEEFGGRESHKEICVYSPAFKEAEMSAILPLATSIIFNSFYQYATYKDRILDK 124 Query: 124 PKA--------ISCGIRVNPEYSEIEVPLYDPCYNYSRMGVTLPNF----RPEELDGIDG 171 K I G+R+NP YSE+ +Y+PC SR+G+T F + L+G+ G Sbjct: 125 NKQLENLGLSPIKMGLRINPLYSEVTPAIYNPCSKVSRLGITPSGFEKGVKEHGLEGVSG 184 Query: 172 LHFHTMCEQNSDTLERTLKVVEEKFGQYLHGMKWLNFGGGHHITRPDYDLETLIRCILHM 231 LHFHT CEQN+D L RTL+ VE+ F YL M W+NFGGGHHIT+ DYD+ LI+ I Sbjct: 185 LHFHTHCEQNADALCRTLEHVEKHFRPYLENMAWVNFGGGHHITKSDYDVNLLIQTIKDF 244 Query: 232 KETY-NVQIYLEPGEAVALNTGYLVATVLDTMHNGMDIAILDTSAECHMPDVLAMPYRPG 290 KE Y N+++ LEPGEA+ G+L+A+V+D + N +IAILD S HMPD L MPYRP Sbjct: 245 KERYHNIEVILEPGEAIGWQCGFLIASVIDIVQNDQEIAILDASFSAHMPDCLEMPYRPS 304 Query: 291 IIGAG----------EPGEY--PYTYRLGGMTCLAGDVIGDYSFKEPLKYGDKLVFLDMA 338 I E GE ++Y LGG TCLAGD +G +SF+ PLK GDK+VF DM Sbjct: 305 IFKVSVENDEELIEVEKGENQGAFSYFLGGPTCLAGDFMGSFSFETPLKRGDKIVFQDML 364 Query: 339 HYSMVKNHMFNGVNLPAIASYNDEEGLKVIREFEYQDFSNR 379 HY++VKN+ FNGV LP++A D++G K+++ F Y+D+ NR Sbjct: 365 HYTIVKNNSFNGVPLPSLARL-DQQGFKILKNFSYEDYKNR 404 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.139 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 31,355,852 Number of extensions: 1369525 Number of successful extensions: 3764 Number of sequences better than 1.0e-05: 12 Number of HSP's gapped: 3729 Number of HSP's successfully gapped: 12 Length of query: 381 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 273 Effective length of database: 25,922,359 Effective search space: 7076804007 Effective search space used: 7076804007 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 117 (49.7 bits)