BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0564.0035.p (470 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-... 330 4e-90 BS_ydeL [KE] COG1167 Transcriptional regulators containing a DNA... 295 1e-79 BS_yhdI [KE] COG1167 Transcriptional regulators containing a DNA... 279 6e-75 BH2695 [KE] COG1167 Transcriptional regulators containing a DNA-... 270 4e-72 FN1462 [KE] COG1167 Transcriptional regulators containing a DNA-... 248 2e-65 >BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 330 bits (845), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 184/454 (40%), Positives = 273/454 (60%), Gaps = 15/454 (3%) Query: 3 LVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQL 62 + P L + P Y+QLY Y K+ I S L + T LPSIR LA L++S VE AYQQL Sbjct: 4 ITPFLDSKRKTPLYVQLYQYIKEGIESGQLKSDTFLPSIRELALHLRVSKNTVEGAYQQL 63 Query: 63 LSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSPLTLRPIT----PRDSRTYPYDFHISRN 118 ++EG++ S PR G + ++ A D+ L+ +T R+ ++ +DF Sbjct: 64 IAEGYVESIPRVGLKILELE----ATFLCDKGGKQLQNVTMGEIQREHKSIEFDFVYGEI 119 Query: 119 DFSLFPDKIWRSLYQEQL--ANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVI 176 D + P K+W+ QE L A+ +LL YGDP G+ LR+ ++ +L Q RG+ C EQVVI Sbjct: 120 DTAHLPLKVWKRHVQEVLKGASEELLMYGDPFGDWHLRQELSHYLLQSRGVSCRPEQVVI 179 Query: 177 GGDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYA 236 SLL LL +A E+PGY+ + + F G +I P+ ++ DGL +++L+ Sbjct: 180 TAGTQHAVSLLCQLLSLHGSTVAFEDPGYNGVRSVFINQGCRIAPIPIEADGLSLSRLHE 239 Query: 237 SGANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQG 296 S AN VY++PSHQ P GM++P+ KR LLEWA + GYI+EDDYD EFRY G+PIPAL+ Sbjct: 240 SHANIVYVTPSHQLPCGMILPVHKRSLLLEWAYEHEGYIVEDDYDSEFRYQGQPIPALKA 299 Query: 297 LLEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHYF 356 L ++ VIY+ +F++S P++ + YMVLP LVP Y + + +AS+L Q AL+ F Sbjct: 300 LDQNEKVIYLGTFSKSFLPSIRVSYMVLPGELVPLYQQKLAN--YNQAASQLIQRALYTF 357 Query: 357 MERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQL 416 ++ G F +H+RRM+ VYQ KH LL +++ + G+ V G+ +G H+LL + G +L Sbjct: 358 IKDGDFQRHIRRMKKVYQSKHHTLLKSVKTYLGDRVTVIGEKSGLHVLLNV-PGREDHEL 416 Query: 417 AEKAAAAGIRVTPMSYTWWSGPEHDAPEFI-LGF 449 EKA A G++V + T+W P++ FI LGF Sbjct: 417 IEKAMACGVKVYS-TKTFWYNPKNQCSSFIMLGF 449 >BS_ydeL [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 463 Score = 295 bits (755), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 172/441 (39%), Positives = 254/441 (57%), Gaps = 11/441 (2%) Query: 1 MLLVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQ 60 M + P L+ T +P Y QLY YFK+ + + G +LPS R+LA QL +S T VE AY+ Sbjct: 1 MDITPFLNRTLDIPLYQQLYRYFKENMHRGRIQKGMKLPSKRLLANQLSISQTTVERAYE 60 Query: 61 QLLSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPY-DFHISRND 119 QL +EG+IVSKPRSG++ H A DR P T PI + DFH D Sbjct: 61 QLAAEGYIVSKPRSGWFAD-YHDSDFAY---DRMPSTT-PIQQEAEENKQWIDFHYGNVD 115 Query: 120 FSLFPDKIWRSLYQEQLAN--PDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVIG 177 S FP WR L +L + G GE LR IA +L Q RG+ C EQV+IG Sbjct: 116 SSYFPFSAWRKSMVNSLDQYGHELYRPGHVLGEFELRTLIAEYLYQSRGVHCGPEQVIIG 175 Query: 178 GDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYAS 237 L +L + E + + E+PGY F+ + I+P+ + ++G+ + ++ Sbjct: 176 AGNPILLQILCQVF-EPNISIGYEDPGYPRARKIFEANRMNIVPIPVDDEGICIQKIKEQ 234 Query: 238 GANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQGL 297 N VY++PSHQF G +M I +R+ LL+WA N +IIEDDYDGEFRY G+P+P+LQGL Sbjct: 235 QPNLVYVTPSHQFTLGTIMTINRRIQLLKWAAENQSFIIEDDYDGEFRYTGQPVPSLQGL 294 Query: 298 LEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHYFM 357 + + VIYM +F++SL P+L I YM+LP PL+ H + S LY + + S +Q+ L F+ Sbjct: 295 DQHNRVIYMGTFSKSLLPSLRISYMILPSPLLKKGHEITS-LY-KQTVSCHSQLTLAEFI 352 Query: 358 ERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQLA 417 + G + KH+ RMR +Y++K ++L A+Q+ GE + G+ +G ILL + ++L Sbjct: 353 KNGEWQKHINRMRKLYRKKRAIVLEAVQRELGEHVRIRGENSGLRILLDVYLPFGEKELI 412 Query: 418 EKAAAAGIRVTPMSYTWWSGP 438 EKA G+++ P+S ++ P Sbjct: 413 EKAKKHGVKIYPVSLSYQHHP 433 >BS_yhdI [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 279 bits (714), Expect = 6e-75, Method: Compositional matrix adjust. Identities = 161/437 (36%), Positives = 242/437 (55%), Gaps = 10/437 (2%) Query: 1 MLLVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQ 60 M + P L + P Y QLY +FK+ I + + GTRLPS R L++ L +ST +E AY+ Sbjct: 1 MDITPFLDKKSKTPLYEQLYTFFKQEISHARITKGTRLPSKRRLSSLLDVSTATIERAYE 60 Query: 61 QLLSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRNDF 120 QL +EG++ SKP+ G++ +V G PD +++P DFH D Sbjct: 61 QLTAEGYVKSKPKIGWFAAEVEP--GFPTAPDHFQQSVQPGL-HQKNAPAIDFHQGSVDP 117 Query: 121 SLFPDKIWRSLYQEQLA--NPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVIGG 178 +LFP WR + L + GDPQGE LR IA +R RG+ C Q++IG Sbjct: 118 TLFPFNAWRKSIVKSLDRYSGSFHTSGDPQGEYELRHMIARFVRLSRGVNCEPGQIIIGA 177 Query: 179 DQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYASG 238 L L L L+ K+ E PG+H F+ + + P+ +G+ +LY Sbjct: 178 GTTVLLQNLCLSLK-PGTKIGFEEPGFHRSRRMFEANHMDVTPICSDAEGVLPDELYRQN 236 Query: 239 ANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQGLL 298 +Y +PSHQFP G +M I +R LL WA N +IIEDDYDGEFRY G PIP+LQGL Sbjct: 237 PYLMYTTPSHQFPIGTIMTITRRQELLAWAAETNSFIIEDDYDGEFRYSGHPIPSLQGLD 296 Query: 299 EDSPVIYMCSFAQSLAPALCIHYMVLPKPLV-PDYHRLKSELYLEHSASRLNQIALHYFM 357 + VIY+ +F++SL P+L + +M++P L+ P + ++ ++ + S +Q+AL F+ Sbjct: 297 PNGRVIYLGTFSKSLLPSLRLSFMIVPPELMEPIQNNVQ---LMKQTVSAHSQLALADFI 353 Query: 358 ERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQLA 417 E G + KH+ RMR +Y++KH +LL AI+ G T + G+ +G HILL L S + Sbjct: 354 ETGEWQKHINRMRSLYRKKHAVLLEAIRSELGNTVEILGKNSGLHILLRLLFPASEEEAI 413 Query: 418 EKAAAAGIRVTPMSYTW 434 + AA G+ + P+S ++ Sbjct: 414 QAAADHGVTLYPVSPSY 430 >BH2695 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 462 Score = 270 bits (690), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 166/453 (36%), Positives = 247/453 (54%), Gaps = 16/453 (3%) Query: 1 MLLVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQ 60 M L L P Y QLY+ +K I+S L TG +LPSIR A L +S V+ AY Sbjct: 1 MTLTYFLDKETDTPIYKQLYESLRKDILSGKLKTGAKLPSIRHFAQTLNVSVITVQNAYH 60 Query: 61 QLLSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRNDF 120 QL +EG+I S+ RSGYYV+ + GL E + + P + S DF S D Sbjct: 61 QLEAEGYITSRDRSGYYVENLAGL--TLLERQDAKIIHAPHHDQASEDQIIDFSPSNIDN 118 Query: 121 SLFPDKIWRSLYQEQLANPD--LLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVI-G 177 + FP IWR E L N + +G GE LR ++A ++ + R L CT EQVVI Sbjct: 119 AQFPLSIWRKCVNETLLNHETRFNHHGAKLGELPLRAAVADYVTKSRILDCTEEQVVIFE 178 Query: 178 GDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYAS 237 G ++++ ++L+LL ++ +E P Y ++ F H I + + L + L Sbjct: 179 GIEHSM-NILSLLFKQMGKTAIMEQPSYKVIEDIFSLHQLPIQRVPSPKGVLSLEDLQEQ 237 Query: 238 GANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQGL 297 +YL+PSHQ+P G + I +R+ ++ WA+ + Y+IEDDYDGEFRY P+P+LQGL Sbjct: 238 KNGVLYLTPSHQYPYGSFLSIQERIKIINWAQNSESYVIEDDYDGEFRYDIDPVPSLQGL 297 Query: 298 LEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHYFM 357 ++ VIY+ +F+++L+PA+ + Y +LP L+ Y + S S Q+AL FM Sbjct: 298 SKNH-VIYIGTFSKTLSPAIRVSYAILPPELMKRYQEVCS--MFPSPVSVHLQLALAKFM 354 Query: 358 ERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSA-RQL 416 E GH+ +H+RRMR Y+ K D L+ IQ+ G+ AA+HG AG H++L L++ +QL Sbjct: 355 EDGHYERHIRRMRKYYKEKQDFLIATIQEVMGDHAALHGTTAGLHLVLELKNNSRPYKQL 414 Query: 417 AEKAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 A A G+ + P+ + P FILGF Sbjct: 415 LAAARAHGVNIYPVKDVTPN------PYFILGF 441 >FN1462 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 248 bits (633), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 145/460 (31%), Positives = 235/460 (51%), Gaps = 27/460 (5%) Query: 2 LLVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQ 61 +++ NL + +VP YIQ+Y K+ I + L +LPS + +S ++ A Sbjct: 1 MIILNLVNKSKVPLYIQIYTEIKELIQNKVLKANEKLPSKKDFIDYYNISQNTIQNALYL 60 Query: 62 LLSEGFIVSKPRSGYYVQQVHGL--GGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRND 119 LL EG+I S R GY+V + L E R ++ + YDF S D Sbjct: 61 LLEEGYIFSIERKGYFVSDIENLIVHNVKIENKRQY--------KEKKKIHYDFSYSGVD 112 Query: 120 F-----SLFPDKIWRSLYQEQLANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQV 174 ++F +I + +Y E+ N DLL G QG+ LR+SI +L Q RG + AEQ+ Sbjct: 113 SKSLAKTIFK-RITKDVYDEE--NEDLLFQGHIQGDLLLRKSICEYLSQSRGFKVEAEQL 169 Query: 175 VIGGDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQL 234 +I L ++ L K +ENP + + F + + L E G+ + L Sbjct: 170 IISSGTEYLFYIIFKLFNNKIY--GLENPCHKMFKELFLTNDVSFKAISLDESGIMIEDL 227 Query: 235 YASGANAVYLSPSHQFPRGMVMPIAKRLALLEWARAN-NGYIIEDDYDGEFRYHGRPIPA 293 N Y++PSHQFP G +M I++R LL WA N N YI+EDDYD EF+Y GRPIPA Sbjct: 228 KKFNVNIAYVTPSHQFPTGTIMSISRRTELLNWANENPNRYIVEDDYDSEFKYTGRPIPA 287 Query: 294 LQGLLEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIAL 353 L+ + VIY+ SF++S++PA+ + Y+VLPK L+ Y K Y LNQ L Sbjct: 288 LKATDINDKVIYLGSFSKSISPAIRVSYLVLPKELLNIYQ--KKLPYFICPVPTLNQKIL 345 Query: 354 HYFMERGHFAKHLRRMRLVYQRKHDLLLNAIQQH----FGETAAVHGQGAGFHILLALRS 409 + F++ G+F KH+ +MR +Y++K + L+N I+ + G+ ++ G AG H+++ L Sbjct: 346 YRFIKDGYFVKHINKMRTLYKKKREYLVNTIKMYSSEILGKEISIQGADAGLHLVIKLNK 405 Query: 410 GGSARQLAEKAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 + + ++ +++ + + ++ F+LG+ Sbjct: 406 KINEKMFLKECLENSLQLYSLEEYYLEKIYNETSSFLLGY 445 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.139 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,361,227 Number of extensions: 1443722 Number of successful extensions: 3098 Number of sequences better than 1.0e-05: 75 Number of HSP's gapped: 2937 Number of HSP's successfully gapped: 76 Length of query: 470 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 360 Effective length of database: 25,691,691 Effective search space: 9249008760 Effective search space used: 9249008760 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 118 (50.1 bits)