BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0563.0005.p (457 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA2337 [P] COG0370 Fe2+ transport system protein B 146 6e-35 CAC1031 [P] COG0370 Fe2+ transport system protein B 140 4e-33 STM0051 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase 136 6e-32 MA3477 [P] COG0370 Fe2+ transport system protein B 131 2e-30 AF2394 [P] COG0370 Fe2+ transport system protein B 116 7e-26 >SA2337 [P] COG0370 Fe2+ transport system protein B Length = 664 Score = 146 bits (369), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 128/448 (28%), Positives = 208/448 (46%), Gaps = 49/448 (10%) Query: 15 GAIRDEIVSGIYGVS-------------AGICREAVTYKDQKKLASTYKLDSIVTSKIWG 61 ++RD++ + VS + ++ VTY D+ K + ++D I+T K G Sbjct: 223 SSLRDQVAEQVGAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIG 282 Query: 62 FPIMLAGLGLVFWITIAGANYP-SGWLASFFGWIEGYLTAGFEAV----NAPAWLHGVLV 116 PI LA + L+F T P S L +F G G T + + +L ++ Sbjct: 283 MPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIG---GTFTDSVKTIMNYLGVIPFLQDLIT 339 Query: 117 LGLYRGTSWVISVMLPPMMIFFPVFALLENFGYLPRVAFNMDRLFKKSGGHGKQALTMSM 176 G+ G V+ V +P +++ F +LLE+ GY+ R+A MDR+ + G GK + M + Sbjct: 340 DGIIAGVGSVL-VFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMII 398 Query: 177 GFGCNAAAILSTRIIESPRERMLAILTNNFVPCNGRWPTLILLSSLFMVGGAAAGALRTL 236 GFGCN +I++ R IE+ +ER+ IL F+ C+ R P L +F +L L Sbjct: 399 GFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFF---KENQSLVVL 455 Query: 237 STAXXXXXXXXXXXXXXXXXSWVMSKTALRGVPTHYTLELPPYRRPQIWKTILITSKEKS 296 S S V++KT L+ + +ELP YR P I KT+ ++ EK+ Sbjct: 456 S-------LYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSI-KTLWRSTWEKA 507 Query: 297 LNVLTRAIVVAAPAGILTWILGNVMVGG------DSVLNHMAAFFDPFANLLGLDGFIIM 350 + +A ++ W+L V G S L+ + +FF LG + Sbjct: 508 KGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAG 567 Query: 351 AFIL-GLPANEIVLPILLMGYMSSGAMVDIDGLGGIKDIFLNHGWTWLTALNMMLFSLLH 409 A ++ G A E+++ SS A++ G G+ ++ N +T L+A M+F LL+ Sbjct: 568 ATLVPGFLAKEVIV--------SSMAIIYSSGDAGLVNVIQNQ-FTPLSAYAFMIFILLY 618 Query: 410 YPCGTTLINIYKETRSMKWAVLSAVIPL 437 PC +T+ I KET S KW L+ PL Sbjct: 619 IPCVSTVAAIRKETYSWKWTALAVAYPL 646 >CAC1031 [P] COG0370 Fe2+ transport system protein B Length = 683 Score = 140 bits (353), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 117/423 (27%), Positives = 197/423 (46%), Gaps = 32/423 (7%) Query: 21 IVSGIYGVSAGICREAVTYKDQKKLASTYKLDSIVTSKIWGFPIMLAGLGLVFWITIAGA 80 IV Y + + + +V + ++ +++ K+D ++T+K G PI + V+ ++I Sbjct: 253 IVDKRYELISKFVKNSVKKNEVQEESTSDKIDKVLTNKFLGIPIFAIIMFAVYQVSI--- 309 Query: 81 NYPSGWLASFFGWIEGYLTAG----FEAVNAPAWLHGVLVLGLYRGTSWVISVMLPPMMI 136 N+ +G L+ G L + P + + G++ G V+ P ++I Sbjct: 310 NFGNGTLSDLINDSLGQLGTNIAFTLDGFGVPKIIGAFVRDGVFAGVGSVLG-FFPMILI 368 Query: 137 FFPVFALLENFGYLPRVAFNMDRLFKKSGGHGKQALTMSMGFGCNAAAILSTRIIESPRE 196 F + +LLE+ GY+ R A+ MDRL G HGK A+++ +G GCN A I+S R +ES ++ Sbjct: 369 MFFLISLLEDSGYMARAAYVMDRLMSAVGLHGKTAVSLIVGSGCNVAGIMSARTLESKKD 428 Query: 197 RMLAILTNNFVPCNGRWPTLILLSSLFMVGGAAAGALRTLSTAXXXXXXXXXXXXXXXXX 256 RM+AIL F+ C P + + +F+ A L S Sbjct: 429 RMIAILITPFISC----PARLTVYGVFVGAFFAKQKLGIFSLGGIIIFLLYALGIFVAIC 484 Query: 257 S-WVMSKTALRGVPTHYTLELPPYRRPQIWKTILITSKEKSLNVLTRAIVVAAPAGILTW 315 + S G +++ +ELPPYR P + K ILI EKS + L +A + I+ W Sbjct: 485 AGKFFSSKVFEGETSYFVMELPPYRLPTL-KGILIHMWEKSGHFLKKAGTIILGVCIIVW 543 Query: 316 ILGNVMVG-----GDSVLNHMAAFFDPFANLLGLDGFII-MAFILGLPANEIVLPILLMG 369 IL ++ G DS+L + F P G + +A I G A E V+ Sbjct: 544 ILADLPAGVEYGSKDSLLGIIGTFIAPIFKPAGFGSWQAGVALITGFAAKEAVV------ 597 Query: 370 YMSSGAMVDIDGLGGIKDIF--LNHGWTWLTALNMMLFSLLHYPCGTTLINIYKETRSMK 427 G + I G+ +F +++ +T L+A++ M+ +LL+ PC T+ + ET S K Sbjct: 598 ----GTLGTIYGVNEGTQLFHAIHNTFTPLSAISFMIMTLLYVPCVATIGAVKSETNSNK 653 Query: 428 WAV 430 W V Sbjct: 654 WTV 656 >STM0051 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase Length = 306 Score = 136 bits (343), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 0/410 (0%), Positives = 0/410 (0%), Gaps = 35/410 (8%) Query: 31 GICREAVTYKDQKKLASTYKLDSIVTSKIWGFPIMLAGLGLVFWITIAGANYPSGWLASF 90 Sbjct: 261 320 Query: 91 FGWIEGYLTAGFEAVNAPAWLHGVLVLGLYRGTSWVISVMLPPMMIFFPVFALLENFGYL 150 Sbjct: 321 ----- 375 Query: 151 PRVAFNMDRLFKKSGGHGKQALTMSMGFGCNAAAILSTRIIESPRERMLAILTNNFVPCN 210 Sbjct: 376 435 Query: 211 GRWPTLILLSSLFMVGGAAAGALRTLSTAXXXXXXXXXXXXXXXXXSWVMSKTALRGVPT 270 Sbjct: 436 ---------- 485 Query: 271 HYTLELPPYRRPQIWKTILITSKEKSLNVLTRAIVVAAPAGILTWILGNVMVGGDSVLNH 330 Sbjct: 486 -- 543 Query: 331 MAA--------FFDPFANLLGLDGFIIMAFILGLPANEIVLPILLMGYMSSGAMVDIDGL 382 Sbjct: 544 --------- 594 Query: 383 GGIKDIFLNHGWTWLTALNMMLFSLLHYPCGTTLINIYKETRSMKWAVLS 432 Sbjct: 595 - 643 >MA3477 [P] COG0370 Fe2+ transport system protein B Length = 670 Score = 131 bits (330), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 119/434 (27%), Positives = 198/434 (45%), Gaps = 47/434 (10%) Query: 10 KLADKGAIRDEIVSGIYGVSAGICREAVTYKDQKKLASTYKLDSIVTSKIWGFPIMLAGL 69 ++ADK R E +S I + C E ++ D +D ++T++ G PI L + Sbjct: 251 EMADK---RYEFISSILSQACTTCVEKMSPSDM--------VDKVLTNRYLGIPIFLTLM 299 Query: 70 GLVFWITIAGANYPSGWLASFFGWIEGYLTAGFEAVNAPAWLHGVLVLGLYRGTSWVISV 129 +F +T A+ + FFG + + A ++ +WL +L G+ G VI + Sbjct: 300 WGMFELTFTFASPFMELIDMFFGSLAETVAANIDS----SWLASLLGDGIIAGVGSVI-L 354 Query: 130 MLPPMMIFFPVFALLENFGYLPRVAFNMDRLFKKSGGHGKQALTMSMGFGCNAAAILSTR 189 +P + I F + ALLE+ GYL R AF MDRL G GK + M MGFGC+ AI++TR Sbjct: 355 FVPNIFILFFLLALLEDSGYLARAAFIMDRLMYSMGLQGKSFIPMLMGFGCSVPAIMATR 414 Query: 190 IIESPRERMLAILTNNFVPCNGRWPTLILLSSLFMVGGAAAGALRTLSTAXXXXXXXXXX 249 +E ++R++ ++ F+ C R P +LL+ F G AG++ Sbjct: 415 TLEDEKDRLITMMVTPFMSCGARMPVYVLLAGTFF--GKQAGSV--------IFGLYVLG 464 Query: 250 XXXXXXXSWVMSKTALRGVPTHYTLELPPYRRPQIWKTILITSKEKSLNVLTRAIVVAAP 309 + + +G P+ + +ELPPY P + ++ + SL L R V Sbjct: 465 IIVAILSAKLFRSVIFKGKPSSFIMELPPYHLPSVGNSLKHMWNQGSL-YLKRVGTVITG 523 Query: 310 AGILTWILGNVMVG-----GDSVLNHMAAFFDPFANLLGLDGFIIMAFILGLPANEIVLP 364 ++ W+L G +S + + +P +G D I ++ I G A E+VL Sbjct: 524 GVVIIWLLAYFPQGVEYGSAESYIGSLGKLIEPLVAPIGFDWKIAISLIFGFLAKEVVL- 582 Query: 365 ILLMGYMSSGAMVDIDGLGGIKDIF-----LNHGWTWLTALNMMLFSLLHYPCGTTLINI 419 G++ + G G + I + +T AL +M+F+LL+ PC + I Sbjct: 583 ---------GSLGTLYGTGEDEGILSSTLAADPTFTPAIALGLMVFTLLYVPCIGAVAVI 633 Query: 420 YKETRSMKWAVLSA 433 KE+ S KW + +A Sbjct: 634 KKESGSWKWMLFAA 647 >AF2394 [P] COG0370 Fe2+ transport system protein B Length = 563 Score = 116 bits (291), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 110/427 (25%), Positives = 188/427 (44%), Gaps = 48/427 (11%) Query: 12 ADKGAIRDEIVSGIYGVSAGICREAVTYKDQKKLASTYKLDSIVTSKIWGFPIMLAGLGL 71 A +G + D I + I RE + +K D + K G PI L+ + + Sbjct: 161 AFRGNLED-----IIRTTEKIAREVTVAEKPEKSEIEEAFDEVFMDKHLGIPIFLSFMWM 215 Query: 72 VFWITIAGANYPSGWLASFFGWIEGYLTAGFEAVNAPAWLHGVLVLGLYRGTSWVISVML 131 +F T + A + L+ F + Y+ A F+ W +L G+ G V+S + Sbjct: 216 MFVFTYSVAQPLNDLLSITFDAMASYI-ASFDG-----WFFSMLGNGVVAGVGSVLS-FV 268 Query: 132 PPMMIFFPVFALLENFGYLPRVAFNMDRLFKKSGGHGKQALTMSMGFGCNAAAILSTRII 191 P + F ++LE GY+PR F +D + G +G+ + + MGFGCN AIL+TR I Sbjct: 269 PNIAFLFLFLSMLELSGYMPRAVFLVDGFMSRFGLNGRAVIPLIMGFGCNVPAILATRSI 328 Query: 192 ESPRERMLAILTNNFVPCNGRWPTLILLSSLFMVGGAAAGALRTLSTAXXXXXXXXXXXX 251 E + R+ L N F+ C+ R P +L + +F G++ +S Sbjct: 329 EDRKVRIATALINPFMSCSARLPIYVLFAGVFF---PKMGSVVIMS-------MYLIGVL 378 Query: 252 XXXXXSWVMSKTALRGVPTHYTLELPPYRRPQIWKTILITSKEKSLNVLTRAIVVAAPAG 311 + ++ KT L+G + + +ELPPY P + K + I + ++ + + +A V Sbjct: 379 IALISALILRKTLLKG-ESEFIMELPPYMLPNL-KELWIMTWSRTKHFIQKAGTVILAMS 436 Query: 312 ILTWILGNVMVGGDSVLNHMAAFF----DPFANLLGLDGFIIMAFILGLPANEIVLPILL 367 ++ W + G S+ AA P + +G +++A I G A E+V+ + Sbjct: 437 VVVWYITT--YPGGSIEESYAAMLGKAIQPIFSPMGWSWELVLALISGFVAKEVVVATI- 493 Query: 368 MGYMSSGAMVDIDGLGGIKDIFLNHGWTWLTALNMMLFSLLHYPCGTTLINIYKETRSMK 427 +++ID I+ I H A MLF+LL+ PC T+ I E + K Sbjct: 494 -------GVLNID----IRSIMTPH-----QAFAYMLFTLLYMPCVATIAAIRAEIGA-K 536 Query: 428 WAVLSAV 434 WA + + Sbjct: 537 WAAFAVI 543 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.326 0.140 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 32,036,300 Number of extensions: 1290897 Number of successful extensions: 4523 Number of sequences better than 1.0e-05: 11 Number of HSP's gapped: 4496 Number of HSP's successfully gapped: 12 Length of query: 457 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 347 Effective length of database: 25,691,691 Effective search space: 8915016777 Effective search space used: 8915016777 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 117 (49.7 bits)