BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0560.0037.p (783 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins 519 e-147 BS_yesS [K] COG2207 AraC-type DNA-binding domain-containing prot... 117 7e-26 BH3679 [T] COG4753 Response regulator containing CheY-like recei... 82 3e-15 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 81 6e-15 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 76 2e-13 >BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 769 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 274/768 (35%), Positives = 448/768 (58%), Gaps = 13/768 (1%) Query: 9 SFLSKLTMFAFVLSTLPVLFIGSFSYFTSSREIQKNVNRSKMELILQITSNVEHKLATVN 68 +F +L +F +LSTLPVL +G+FSY +S I + V+ K + Q +N+EH L T + Sbjct: 7 TFYVRLILFILILSTLPVLLVGTFSYIKASDAIHEQVSEDKRSSVYQTQTNIEHILKTAD 66 Query: 69 QTLNQVVNSSVLKKALNNPLNVTDFILYNDIRTEIRNMQSFDTKLEDVILLNQRQNWMIK 128 +L VNSS+L+ LN PL T F LYNDIR E+ ++Q+++ +ED++LL+ Q W++ Sbjct: 67 HSLTYFVNSSLLRDTLNQPLTATQFQLYNDIRKELTHLQTYEIGIEDIVLLSTNQEWLMN 126 Query: 129 NSGLYRLNEYKNYEQLTNLINLPDESSWVLNPSSLF--YSEESINVTGCAYSISLIKKLP 186 N GL R+ + + + LP S+W+ + ++EE N C+ ++L+KKLP Sbjct: 127 NWGLQRITKKEIDDHFQRYFELPVNSTWIYEVDTWGSEFNEELAN--SCSTQMNLVKKLP 184 Query: 187 TTKLQKYGLAMANIPACSLQDFINSDVQPLDSIIVLDSSGRILLHPDRTLIGQPVAASG- 245 QK GLA+A+IPACS+ ++ + Q ++ +LD R + + + +++ + + G Sbjct: 185 LNSNQKTGLAIASIPACSVNKILSENSQN-EAFFLLDEQYRPVGYHNLSILEDDLLSDGT 243 Query: 246 FTEFAQLTAAATPSGQFKTVMDNKDYSITYMRSQQSGWIYLSVTSIASLTKESDKIGTXX 305 E A +GQF + + Y++T+ S + W Y+SV S L K+S+ IG Sbjct: 244 LIEALATQQTANGNGQFSLPLSHSTYTVTFRTSDYNQWTYVSVISSRELAKQSNAIGAFT 303 Query: 306 XXXXXXXXXXXXXXAWLGSRKMYTPIERLLNQIGQ--RRPDIRKKHTNEFQVIGEQVHHL 363 +W+GSR++Y P++ L I +K +EF++I +H++ Sbjct: 304 MYISAGVLLLSLLYSWVGSRRIYRPVQELYQMITATFSAGSAKKPPKDEFELIHAHIHNV 363 Query: 364 FQSKSRLEKEVAQHLQQVRTFGLIKAFQGHIKKRELLEELEQFGYHTQLEEWQTMAVITI 423 + LE+++ ++Q++ F ++ +GH+ E+ + E F Y ++W+ + V+T+ Sbjct: 364 LDLNNELEEKLQGQIKQLKQFFVLNLIKGHMSPSEIETKYETFQYP---KDWRQLHVLTL 420 Query: 424 SLDFSEENSYLKKDLSLLLFAVHNMIEELVPSSSRLTPVIMDHAVVTLIGSADGHAESFH 483 +D E Y K++ +LLF+++N++E L+P RLTP ++++ VV ++ + + Sbjct: 421 QIDSLEGTKYAKEEKDVLLFSINNLVETLIPEVERLTPALLNNTVVLILLTNVDQEQKRD 480 Query: 484 KMLYSLTESLQQTINSYLKLEASIGLSLPFHAFDKMSIAYREGLEALKHRITLGKGIIIQ 543 + E++ + L + SIG+SLP+ K AY EG+EALK+RI LG +I Sbjct: 481 GFVREKAEAIMNEVRQQLDISVSIGVSLPYDDITKTQEAYDEGIEALKYRIKLGCQSVIF 540 Query: 544 YENINSGNHYLNLSYPVHKENDLMDAIKLADAGKAKEVLHKVFSCIFAPGLSPQEYQIPL 603 + N+ + H + YP +EN+L DA+KL D K+ L + IF L P +YQI L Sbjct: 541 FSNL-AHTHSFHTYYPKQQENELFDALKLGDKSNVKDHLDALIDGIFQKDLHPSQYQISL 599 Query: 604 TRLLNNLLIMMQESGISLNQIHPGNGSLFEELTDIHIVAEIEDWFWTVVIQPMIRIFGSR 663 RLLNN + ++Q GI ++ +LF++L + + E++ WF+T +I P + R Sbjct: 600 LRLLNNTIQLLQTLGIDSVDVY-DKKTLFDQLFSLQTIDEVKQWFFTKLIAPSVHTVAER 658 Query: 664 QNAQYHNISEKLIDIVQHDYDKDLTLEECASRLHYNANYISSVFRKETQYYFSEYLAMYR 723 ++QY IS+++I I+Q+++D +LTLE A RLHYN NY+SS+FRKET FSEYL+ YR Sbjct: 659 MDSQYRTISDQIIHIIQNEFDMELTLESIAERLHYNPNYLSSIFRKETNISFSEYLSSYR 718 Query: 724 FKMAKKWLKETDMPIKDIAARLRYNNSQNFIRSFRKQEGMTPGQYREN 771 MAKKWL ET MPI++IA RL Y NSQNFIRSF+K+EGMTPG+YR++ Sbjct: 719 LAMAKKWLLETSMPIREIAERLCYGNSQNFIRSFKKKEGMTPGKYRQS 766 >BS_yesS [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 761 Score = 117 bits (293), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 151/780 (19%), Positives = 310/780 (39%), Gaps = 59/780 (7%) Query: 9 SFLSKLTMFAFVLSTLPVLFIGSFSYFTSSREIQKNVNRSKMELILQITSNVEHKLATVN 68 ++ + +F +++ +P L G YF S +++K + RS + + S ++ KL + Sbjct: 17 TYFKRNFVFILLIACIPGLLTGGAIYFLSIDKVEKELQRSHETQVAREVSRMDEKLGVLE 76 Query: 69 QTLNQVVNSSVLKKALNNPLNVTDFILYNDIRTEIRNMQSFDTKLEDVILLNQRQNWMIK 128 L Q+ S L L DF +F +L + L + Q +I+ Sbjct: 77 LALTQMAYDSSLMNGLAERDLEKDF--------------TFSYQLTKKLFLLRDQQPLIE 122 Query: 129 NSGLYRLNEYK------NYEQLTNLINLPDESSWVLNPSSLFYSEESINVTGCAYSISLI 182 + ++ LN + Y LT E + SL S+ SI LI Sbjct: 123 QASIF-LNSPRPLVLSPEYSALT-------EQEALRKYRSLLASDHSIYWKRSGNQAMLI 174 Query: 183 KKLPTTKLQKYGLAMANIPACSLQDFINS-DVQPLDSIIVLDSSGRILLHPDRTLIGQPV 241 + +P + +G M + ++ + S P S ++LD + +L H + Sbjct: 175 QLIPGAAEKPFGAIMLAVDPKEMESILQSLSPYPDGSALLLDQNREVLFHEGEKDFEK-- 232 Query: 242 AASGFTEFAQLTAAATPSGQFKTVMDNKDYSITY--MRSQQSGWIYLSVTSIASLTKESD 299 T ++ +G F+ K YS+++ M W ++S ++++T Sbjct: 233 -----TLLHEIKKQPAENGHFQMEWKGKVYSVSFGEMNRMHQQWTFVSAAPLSAITAPMV 287 Query: 300 KIGTXXXXXXXXXXXXXXXXAWLGSRKMYTPIERLLNQI-GQRRPDIRKKHTNEFQVIGE 358 + W S+K+Y PI+ LL G + + +EF+ I + Sbjct: 288 FLSKVIIVMLVICIGLAVCMTWYASKKIYRPIQHLLGLFTGGEKKTWQASGQDEFKWIEK 347 Query: 359 QVHHLFQSKSRLEKEVAQHLQQVRTFGLIKAFQGHIKKRELL-EELEQFGYHTQLEEWQT 417 + L +L++++ + ++ K+F H+ + + + E + + W Sbjct: 348 RWQDLSLESRKLQQQLLRQTPHMK-----KSFLQHLLQSDFYYDNEESLRFRMEEAGWNI 402 Query: 418 MAVITISLDF------SEENSYLKKDLSLLLFAVHNMIEELVPSSS-RLTPVIMDHAVVT 470 + LD E++ + + D L +F + N+ EEL +L+ + + VT Sbjct: 403 GGNVFHVLDLQVTGLRCEKSIFREGDEQLAVFTLTNIAEELAAKRVFQLSILDIGRLSVT 462 Query: 471 LIGSADGHAESFHKMLYSLTESLQQTINSYLKLEASIGLSLPFHAFDKMSIAYREGLEAL 530 ++ ++ L + L + L + LS ++ +++ Sbjct: 463 VLVMKTNSSD-----LKAYITELARQFGDVTGLCLTSTLSSKTERVTEIPSLFQDVKCGK 517 Query: 531 KHRITLGKGIIIQYENINSGNHYLNLSYPVHKENDLMDAIKLADAGKAKEVLHKVFSCIF 590 R + +I + + YP E ++ I+L +AKE++ + Sbjct: 518 SRRKFANRDQVIDLQADFPRDEQFAPYYPFELEKQIVQTIRLERKQEAKELIDGCMKELS 577 Query: 591 APGLSPQEYQIPLTRLLNNLLIMMQESGISLNQIHPGNGSLFEELTDIHIVAEIEDWFWT 650 + L +L + + + SG++ +++ F +++++ E W Sbjct: 578 EKAAIDRHVHSALIQLFSRIQEDILHSGLNPSELFQHRNP-FLDISELREPNEAAAWLMD 636 Query: 651 VVIQPMIRIFGSRQNAQYHNISEKLIDIVQHDYDKDLTLEECASRLHYNANYISSVFRKE 710 VV+ P + R+N Q ++E++I ++ Y D++LE CA L N+ +S F++ Sbjct: 637 VVVTPYLSKLEGRKNRQQKQLAERVIAMIHEQYMADISLESCADALGMNSYTLSKAFKQV 696 Query: 711 TQYYFSEYLAMYRFKMAKKWLKETDMPIKDIAARLRYNNSQNFIRSFRKQEGMTPGQYRE 770 T F +Y+ R + AK+ L T+ I D++ + Y ++ F R F+KQ GM PG +R+ Sbjct: 697 TGINFIDYVTQIRIEKAKELLVNTNKKIHDVSEEVGYRHN-YFNRIFKKQVGMPPGVFRQ 755 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 82.0 bits (201), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 37/88 (42%), Positives = 57/88 (64%) Query: 684 DKDLTLEECASRLHYNANYISSVFRKETQYYFSEYLAMYRFKMAKKWLKETDMPIKDIAA 743 D+ + L++ A +H N +Y+S++F+++T FSEYL R + AK L TD PI DIA Sbjct: 168 DQKIGLKDVAKSVHLNPSYLSALFKEKTNMTFSEYLTRKRLQHAKHLLVSTDRPISDIAE 227 Query: 744 RLRYNNSQNFIRSFRKQEGMTPGQYREN 771 + Y ++ FI+ F++ EGMTP QYR+ Sbjct: 228 KCGYQTAKYFIKIFKEHEGMTPTQYRKG 255 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 81.3 bits (199), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 47/173 (27%), Positives = 92/173 (53%), Gaps = 7/173 (4%) Query: 603 LTRLLNNLLIMMQESGISLNQIHPGNGSLFEELTDIHIVAEIEDWFWTV--VIQPMIRIF 660 L ++ N++++M + ++ F + V E D F+ V + +I ++ Sbjct: 335 LGNIIFNMIVLMGNLKYDVKELEREKYHYFATINAAKNVREATDCFYQFLEVTKQIISVY 394 Query: 661 GSRQNAQYHNISEKLIDIVQHDYDKDLTLEECASRLHYNANYISSVFRKETQYYFSEYLA 720 + ++ +K++ ++ + + L+L + A+ H+N +Y+S+ FR+ FSEYL Sbjct: 395 SNEGSSSI----QKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLN 450 Query: 721 MYRFKMAKKWLKETDMPIKDIAARLRYNNSQNFIRSFRKQEGMTPGQY-RENA 772 R + AK+WLK + +PI +I A + Y++ F + F+K+ GM P +Y RENA Sbjct: 451 KVRIRKAKEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRRENA 503 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 76.3 bits (186), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 37/116 (31%), Positives = 67/116 (57%) Query: 667 QYHNISEKLIDIVQHDYDKDLTLEECASRLHYNANYISSVFRKETQYYFSEYLAMYRFKM 726 +Y ++ + ID ++ +Y ++LTL+ A RLH N Y+ F+ ET+ F++YL R + Sbjct: 378 RYSDLVSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQK 437 Query: 727 AKKWLKETDMPIKDIAARLRYNNSQNFIRSFRKQEGMTPGQYRENAGARQRAVPDD 782 A++ L T+ I +IA YN + FI+ F+K G++P ++R+ +A+ D Sbjct: 438 AQQLLLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGD 493 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.134 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 53,467,606 Number of extensions: 2135507 Number of successful extensions: 6484 Number of sequences better than 1.0e-05: 756 Number of HSP's gapped: 6484 Number of HSP's successfully gapped: 757 Length of query: 783 Length of database: 38,378,431 Length adjustment: 114 Effective length of query: 669 Effective length of database: 25,230,355 Effective search space: 16879107495 Effective search space used: 16879107495 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 120 (50.8 bits)