BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0089.p (317 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20887 [S] COG2307 Uncharacterized protein conserved in bacteria 147 2e-35 ML0606 [S] COG2307 Uncharacterized protein conserved in bacteria 144 2e-34 Rv2410c [S] COG2307 Uncharacterized protein conserved in bacteria 144 2e-34 MT2483 [S] COG2307 Uncharacterized protein conserved in bacteria 144 2e-34 mll0716 [S] COG2307 Uncharacterized protein conserved in bacteria 134 2e-31 >SMb20887 [S] COG2307 Uncharacterized protein conserved in bacteria Length = 313 Score = 147 bits (371), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 98/321 (30%), Positives = 153/321 (47%), Gaps = 24/321 (7%) Query: 1 MLNRNAEALFWIGRYIERAENHARLIDVHYHIQQEEDFRAEGHKWSRLIDALGVRNEYQQ 60 ML R A L+W+ RYIERAEN ARLID + AE W ++ + VR Y Q Sbjct: 1 MLGRTANGLYWMFRYIERAENSARLIDAGLRMSLTRSEAAE-DDWDGVLQSADVRELYDQ 59 Query: 61 QFDGFSEQDVLSFITLDLGNANSLFSCVHQARNNLRTLRQHLPSELWDIINSFNLWLGEQ 120 +G + D + F+ D N +S+ SC+ RNN R +R L E W+ IN W+ + Sbjct: 60 VHEGLTSGDAIDFLLRDRTNPSSVMSCIEAGRNNARMVRTALTRETWEAINE--CWIEMK 117 Query: 121 SV----ADILSGPHQFYQQVKERAAMFLGAEQSVMLRGNEWRFIGSGRFLERAENTTRIL 176 + A P + +K RA + GA MLR + F G F+ERA+NT RIL Sbjct: 118 GILARRAKTTDMP-EIIDTIKRRAGLIRGAFHGTMLRNEIFNFSRIGTFIERADNTARIL 176 Query: 177 Q--------AVTVSCKSKDINAIYTQLQAVLKSVSGYQAFRRYYADAMSPESILEFLIVN 228 AV+ S D Q +++L+SVS ++++ Y + P +I +FLI N Sbjct: 177 DVKYYVLLPAVSAVGSSMD----NVQWESILRSVSAHRSYGWVYDAELRPANIADFLIAN 232 Query: 229 AYFPRSIRFSFHKLEEHLAKLRLDSSEKGSGHERVIRQAGKIKAELDYMEKEEMSGDLVE 288 PRS+ + + KL +L L + E+ + HE + G ++++ E+ + Sbjct: 233 GRMPRSLAYCYDKLVSNLGYLAREYGERHAAHETAEQTLGLLRSQ----SIAEIMDQGLH 288 Query: 289 DVLQSLMGSCQKLGRTMEGAF 309 L+ + +LGR + + Sbjct: 289 QYLKEFINQNNRLGREISDGY 309 >ML0606 [S] COG2307 Uncharacterized protein conserved in bacteria Length = 325 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 93/310 (30%), Positives = 158/310 (50%), Gaps = 9/310 (2%) Query: 1 MLNRNAEALFWIGRYIERAENHARLIDVHYHIQQEEDFRAEGHKWSRLIDALGVRNEYQQ 60 ML RNAEAL+WIGRY+ERA++ AR++DV H E+ H L+ LG+ Sbjct: 1 MLARNAEALYWIGRYVERADDTARILDVVVHQLLEDSSVDPDHASRTLLRVLGIELP-DH 59 Query: 61 QFDGFSEQDVLSFITLDLGNANSLFSCVHQARNNLRTLRQHLPSELWDIINSFNLWLGEQ 120 + D +S D+++F T G +S+ + AR N ++ R+ SE W+ +N+ L E+ Sbjct: 60 ELDVWSLTDLVAFSTNAQGG-SSIVDAISAARENAKSAREVTSSETWECLNTTYHALAER 118 Query: 121 SVADILSGPHQFYQQVKERAAMFLGAEQSVMLRGNEWRFIGSGRFLERAENTTRILQAVT 180 A GPH+F ++ RAAMF G S + R + +RF+ GR +ER + T R+L + Sbjct: 119 ERAAKRLGPHEFLSFIEGRAAMFAGLADSTLSRDDGYRFMLLGRAIERVDMTVRLLLSRV 178 Query: 181 VSCKSKDINAIYTQLQAVLKSVSGYQAFRRYYADAMSPESILEFLIVNAYFPRSIRFSFH 240 S +L+S G+ + R Y + ++EF++++ FPRSI +S Sbjct: 179 GDSASS------PAWVTLLRSAGGHDTYLRTYRGVLDAARVVEFMLLDRLFPRSIFYSLK 232 Query: 241 KLEEHLAKLRLDSSEKGSGHERVIRQAGKIKAELDYMEKEEMSGDLVEDVLQSLMGSCQK 300 E +L +L + + R G+ ++EL++++ + L + L SL +C+ Sbjct: 233 LAEHNLDELLRNPQSRVGATTEAQRLLGQARSELEFVQPGVLLKTL-DSRLASLQTTCRD 291 Query: 301 LGRTMEGAFF 310 +G + +F Sbjct: 292 VGDALVLQYF 301 >Rv2410c [S] COG2307 Uncharacterized protein conserved in bacteria Length = 325 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/311 (31%), Positives = 165/311 (53%), Gaps = 11/311 (3%) Query: 1 MLNRNAEALFWIGRYIERAENHARLIDVHYHIQQEEDFRAEGHKWSRLI-DALGVRNEYQ 59 ML RNAEAL+WIGRY+ERA++ AR++DV H Q ED + + SRL+ LG+ Sbjct: 1 MLARNAEALYWIGRYVERADDTARILDVAVH-QLLEDSSVDPDQASRLLLRVLGIEPP-D 58 Query: 60 QQFDGFSEQDVLSFITLDLGNANSLFSCVHQARNNLRTLRQHLPSELWDIINSFNLWLGE 119 + D +S D+++F T G +S+ + AR N ++ R+ SE W+ +N+ L E Sbjct: 59 HELDVWSLTDLVAFSTNSQGG-SSIVDAISAARENAKSAREVTSSETWECLNTTYNALPE 117 Query: 120 QSVADILSGPHQFYQQVKERAAMFLGAEQSVMLRGNEWRFIGSGRFLERAENTTRILQAV 179 + A GPH+F ++ RAAMF G S +LR + +RF+ GR +ER + T R+L + Sbjct: 118 RERAAKRLGPHEFLSFIEGRAAMFAGLADSTLLRDDGYRFMLLGRAIERVDMTVRLL--L 175 Query: 180 TVSCKSKDINAIYTQLQAVLKSVSGYQAFRRYYADAMSPESILEFLIVNAYFPRSIRFSF 239 + S A T +L+S + + R Y + ++EF++++ FPRS+ S Sbjct: 176 SRVGDSASSPAWVT----LLRSAGAHDTYLRTYRGVLDAGRVVEFMMLDRLFPRSVFHSL 231 Query: 240 HKLEEHLAKLRLDSSEKGSGHERVIRQAGKIKAELDYMEKEEMSGDLVEDVLQSLMGSCQ 299 E +LA+L + + R G+ ++EL++++ + + +E L L +C+ Sbjct: 232 KLAEHNLAELMHNPHSRIGATTEAQRLLGQARSELEFVQPGVLL-ETLESRLAGLQTTCR 290 Query: 300 KLGRTMEGAFF 310 +G + +F Sbjct: 291 DVGDALALQYF 301 >MT2483 [S] COG2307 Uncharacterized protein conserved in bacteria Length = 325 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/311 (31%), Positives = 165/311 (53%), Gaps = 11/311 (3%) Query: 1 MLNRNAEALFWIGRYIERAENHARLIDVHYHIQQEEDFRAEGHKWSRLI-DALGVRNEYQ 59 ML RNAEAL+WIGRY+ERA++ AR++DV H Q ED + + SRL+ LG+ Sbjct: 1 MLARNAEALYWIGRYVERADDTARILDVAVH-QLLEDSSVDPDQASRLLLRVLGIEPP-D 58 Query: 60 QQFDGFSEQDVLSFITLDLGNANSLFSCVHQARNNLRTLRQHLPSELWDIINSFNLWLGE 119 + D +S D+++F T G +S+ + AR N ++ R+ SE W+ +N+ L E Sbjct: 59 HELDVWSLTDLVAFSTNSQGG-SSIVDAISAARENAKSAREVTSSETWECLNTTYNALPE 117 Query: 120 QSVADILSGPHQFYQQVKERAAMFLGAEQSVMLRGNEWRFIGSGRFLERAENTTRILQAV 179 + A GPH+F ++ RAAMF G S +LR + +RF+ GR +ER + T R+L + Sbjct: 118 RERAAKRLGPHEFLSFIEGRAAMFAGLADSTLLRDDGYRFMLLGRAIERVDMTVRLL--L 175 Query: 180 TVSCKSKDINAIYTQLQAVLKSVSGYQAFRRYYADAMSPESILEFLIVNAYFPRSIRFSF 239 + S A T +L+S + + R Y + ++EF++++ FPRS+ S Sbjct: 176 SRVGDSASSPAWVT----LLRSAGAHDTYLRTYRGVLDAGRVVEFMMLDRLFPRSVFHSL 231 Query: 240 HKLEEHLAKLRLDSSEKGSGHERVIRQAGKIKAELDYMEKEEMSGDLVEDVLQSLMGSCQ 299 E +LA+L + + R G+ ++EL++++ + + +E L L +C+ Sbjct: 232 KLAEHNLAELMHNPHSRIGATTEAQRLLGQARSELEFVQPGVLL-ETLESRLAGLQTTCR 290 Query: 300 KLGRTMEGAFF 310 +G + +F Sbjct: 291 DVGDALALQYF 301 >mll0716 [S] COG2307 Uncharacterized protein conserved in bacteria Length = 313 Score = 134 bits (338), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 91/301 (30%), Positives = 148/301 (49%), Gaps = 25/301 (8%) Query: 1 MLNRNAEALFWIGRYIERAENHARLIDVHYHIQQEEDFRAEGHKWSRLIDALGVRNEYQQ 60 +L R A L+W+ RYIERAEN ARL+D + A +W+ ++ + G ++Q Sbjct: 2 LLGRTANGLYWMNRYIERAENMARLVDAGLRMALTRTQNA-SEEWNSVLLSAGSDVAFKQ 60 Query: 61 QFDGFSEQDVLSFITLDLGNANSLFSCVHQARNNLRTLRQHLPSELWDIINSFNLWLGEQ 120 ++ ++ DV F+ D N +S S + ARNN R +R L E W+ IN W+ Sbjct: 61 KYSDYTAADVADFLLRDTSNPSSTMSSIETARNNARMVRTALTRETWESIN--EAWM--- 115 Query: 121 SVADILSGP------HQFYQQVKERAAMFLGAEQSVMLRGNEWRFIGSGRFLERAENTTR 174 S+ +L+ P +K A+ G+ MLR + F G ++ERA+NT R Sbjct: 116 SLKRMLARPIDERDLPSVLDAIKRETALIRGSFYGTMLRNEIFDFSQLGTYVERADNTAR 175 Query: 175 ILQA------VTVSCKSKDINAIYTQLQAVLKSVSGYQAFRRYYADAMSPESILEFLIVN 228 IL ++S ++ Q +++L+SVS ++++R Y P +I ++LI+N Sbjct: 176 ILDVKYYVLLPSISWVGSTLDNY--QWESILRSVSAHRSYRWVYDADYKPTNIADYLILN 233 Query: 229 AYFPRSIRFSFHKLEEHLAKLRLDSSEKGSGH-----ERVIRQAGKIKAELDYMEKEEMS 283 PRS+ F + L EHL L D E+ + H + + +AG IK D E ++ Sbjct: 234 VRMPRSLTFCYRFLSEHLKFLSDDYGERHACHATAEKTQAMLRAGSIKDIFDAGLHEFLA 293 Query: 284 G 284 G Sbjct: 294 G 294 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,156,641 Number of extensions: 911714 Number of successful extensions: 1657 Number of sequences better than 1.0e-05: 11 Number of HSP's gapped: 1626 Number of HSP's successfully gapped: 11 Length of query: 317 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 211 Effective length of database: 26,153,027 Effective search space: 5518288697 Effective search space used: 5518288697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 116 (49.3 bits)