BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0087.p (412 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1730 [S] COG2308 Uncharacterized conserved protein 303 5e-82 mll0717 [S] COG2308 Uncharacterized conserved protein 281 1e-75 SMb20886 [S] COG2308 Uncharacterized conserved protein 272 8e-73 AGc4248 [S] COG2308 Uncharacterized conserved protein 269 6e-72 Rv2411c [S] COG2308 Uncharacterized conserved protein 267 2e-71 >PA1730 [S] COG2308 Uncharacterized conserved protein Length = 470 Score = 303 bits (775), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 153/331 (46%), Positives = 202/331 (61%), Gaps = 4/331 (1%) Query: 56 FYDEMYADERSIRPHYKHVNRMFSGMSPEEXXXXXXXXXXXXXXXGITFTLYNPAQDHPM 115 FYDEM+ R HY+ R + E+ GITFTLY Q Sbjct: 5 FYDEMHDAGGECRSHYREFARWLADTPEEQLLQRRREADLLFHRAGITFTLYGDEQG--T 62 Query: 116 ERTIPFDMIPRIIPKGEWERLEAGIVQRITALNLFIHDIYHEQFIVKDGIVPRRMIISNC 175 ER IPFD IPR IP EW +EAG +QR+ ALNLF+ D+YHEQ I+K G++P +++N Sbjct: 63 ERLIPFDTIPRSIPAAEWAHIEAGCIQRVQALNLFLADLYHEQRILKAGVIPAEQVLAND 122 Query: 176 YFRPEMSGLRVPGGAYVTTSGIDLIRHHDGEYYVLEDNLRTPSGFSYLFKGRSLMNQLFP 235 ++ M GL +PG Y +G+DL+R G YYVLEDNLRTPSG SY+ + R +M +LFP Sbjct: 123 QYQLAMQGLDLPGNVYAHIAGVDLVRDGSGNYYVLEDNLRTPSGVSYMLENRKMMMRLFP 182 Query: 236 ELSLASSIRDVDHSLNRFLSVLRSLSPSRTKDPVIALLTPGEYNSAYYEHAFLAQQMGIH 295 EL + + +DH + L L+ S + P + +LTPG +NSAY+EHAFLA++MG+ Sbjct: 183 ELFVRQRVAPIDHYPDLLLDTLK--RASDVESPSVVVLTPGRFNSAYFEHAFLAREMGVE 240 Query: 296 LVEGRDLVAQDHKVYLKEMNGMXXXXXXXXXXXXXXXXXXAFQPNSLLGVAGLMNAYRAG 355 LVEG DL +D +VY++ G AF P+SLLGV GL+ AYRAG Sbjct: 241 LVEGADLFVRDERVYMRTTAGPQPVDVIYRRIDDAFLDPLAFNPDSLLGVPGLLAAYRAG 300 Query: 356 NIAIANAPGTGVADDKAMYVYVPDMIRYYLN 386 N+ +ANA GTGVADDK++Y YVPDMIR+YL Sbjct: 301 NLVLANAIGTGVADDKSIYPYVPDMIRFYLG 331 >mll0717 [S] COG2308 Uncharacterized conserved protein Length = 478 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 145/329 (44%), Positives = 190/329 (57%), Gaps = 3/329 (0%) Query: 57 YDEMYADERSIRPHYKHVNRMFSGMSPEEXXXXXXXXXXXXXXXGITFTLYNPAQDHPME 116 +DEM + +R Y +R P GITF +Y + E Sbjct: 12 FDEMLPEVSGLRRPYSAYDRWLKEQDPARLTEKMQDAERVFRKTGITFAVY--GEQEASE 69 Query: 117 RTIPFDMIPRIIPKGEWERLEAGIVQRITALNLFIHDIYHEQFIVKDGIVPRRMIISNCY 176 R IPFD++PRII EW RL GI QR+ ALN F+ DIYH Q I++ G VPR +I N Sbjct: 70 RLIPFDIVPRIISGNEWRRLTQGIEQRVQALNAFLDDIYHRQEILRAGRVPRDLIAKNEA 129 Query: 177 FRPEMSGLRVPGGAYVTTSGIDLIRHHDGEYYVLEDNLRTPSGFSYLFKGRSLMNQLFPE 236 F PEM G+R P G Y G+D++R + E+YVLEDN RTPSG SY+ + R M QLFPE Sbjct: 130 FLPEMIGVRPPAGVYTHIIGVDIVRISEDEFYVLEDNARTPSGVSYMLENRETMMQLFPE 189 Query: 237 LSLASSIRDVDHSLNRFLSVLRSLSPSRTKD-PVIALLTPGEYNSAYYEHAFLAQQMGIH 295 L +R V++ L ++ P TK P IA+LTPG +NSAY+EHAFLA QMG+ Sbjct: 190 LFQKIKVRPVENYPQLLRQSLAAVRPQSTKGAPTIAVLTPGSFNSAYFEHAFLADQMGVQ 249 Query: 296 LVEGRDLVAQDHKVYLKEMNGMXXXXXXXXXXXXXXXXXXAFQPNSLLGVAGLMNAYRAG 355 LVEG+DL D V ++ G F+P+S LG+ G+M+ YRAG Sbjct: 250 LVEGQDLRVVDGHVAMRTTEGYKQIDVLYRRVDDSFLDPLTFRPDSALGIPGIMDVYRAG 309 Query: 356 NIAIANAPGTGVADDKAMYVYVPDMIRYY 384 NI IANAPGTG+ADDKA+Y Y+P+++ +Y Sbjct: 310 NITIANAPGTGIADDKAIYSYMPEIVEFY 338 >SMb20886 [S] COG2308 Uncharacterized conserved protein Length = 469 Score = 272 bits (695), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 141/329 (42%), Positives = 193/329 (58%), Gaps = 3/329 (0%) Query: 57 YDEMYADERSIRPHYKHVNRMFSGMSPEEXXXXXXXXXXXXXXXGITFTLYNPAQDHPME 116 +DEM + S R Y ++ ++ GITF +Y A E Sbjct: 3 FDEMINADSSPRQPYSTYHQWYASQDRNRLIAKSKEAEKIFRKTGITFAVYGHADSS--E 60 Query: 117 RTIPFDMIPRIIPKGEWERLEAGIVQRITALNLFIHDIYHEQFIVKDGIVPRRMIISNCY 176 + IPFD+IPRII EW RL GI QR+ ALN F+ DIYH+Q I++ G +PR ++ N Sbjct: 61 KLIPFDLIPRIISGREWRRLAQGIEQRVIALNAFLDDIYHKQEIIRAGRIPRELVEKNDT 120 Query: 177 FRPEMSGLRVPGGAYVTTSGIDLIRHHDGEYYVLEDNLRTPSGFSYLFKGRSLMNQLFPE 236 F P+M G R PGG Y G D++R + +YYVLEDN RTPSG SY+ + R M Q+FPE Sbjct: 121 FLPQMIGFRPPGGVYTHIVGTDIVRTGEDQYYVLEDNARTPSGVSYMLENRETMMQMFPE 180 Query: 237 LSLASSIRDVDHSLNRFLSVLRSLSPSRTK-DPVIALLTPGEYNSAYYEHAFLAQQMGIH 295 L + +R V++ N L SL+P+ + P +A+LTPG YNSA+YEHAFLA MG+ Sbjct: 181 LFHQNRVRPVENYPNLLRQSLSSLAPAGCEGKPRVAVLTPGIYNSAFYEHAFLADMMGVE 240 Query: 296 LVEGRDLVAQDHKVYLKEMNGMXXXXXXXXXXXXXXXXXXAFQPNSLLGVAGLMNAYRAG 355 LVEG DL D +V ++ G F+P+S LG+ G+M+ YRAG Sbjct: 241 LVEGSDLRVIDGRVKMRTTRGYEAIDVLYRRVDDDFLDPLTFRPDSALGIPGIMDVYRAG 300 Query: 356 NIAIANAPGTGVADDKAMYVYVPDMIRYY 384 NI IANAPGTG++DDKA+Y Y+P+++ +Y Sbjct: 301 NITIANAPGTGISDDKAIYSYMPEIVEFY 329 >AGc4248 [S] COG2308 Uncharacterized conserved protein Length = 248 Score = 269 bits (688), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 0/329 (0%), Positives = 0/329 (0%), Gaps = 3/329 (0%) Query: 57 YDEMYADERSIRPHYKHVNRMFSGMSPEEXXXXXXXXXXXXXXXGITFTLYNPAQDHPME 116 + + + + D E Sbjct: 20 MRPITDTIPKPLVKIAGKPMIDYALDALVEAGAETIVVNVHHHAEQMISHLGHRTDA--E 77 Query: 117 RTIPFDMIPRIIPKGEWERLEAGIVQRITALNLFIHDIYHEQFIVKDGIVPRRMIISNCY 176 I + + G + + + E+ + + Sbjct: 78 ILISDERTQLMNSGGGLAKGLKLLKPGPVFVMNADLFWIGERLNAVSNLRKLAQFLDPAR 137 Query: 177 FRPEMSGLRVPGGAYVTTSGIDLIRHHDGEYYVLEDNLRTPSGFSYLFKGRSLMNQLFPE 236 + + + + + + + L++ + Sbjct: 138 MDMALLCVDMDRTTGHNGKRDFNLAGEGKLTRYRDGDANPVVYAGAIAMDSRLLDDAPAD 197 Query: 237 LSLASSIRDVDHSLNRFLSVLRSLSPSRTKD-PVIALLTPGEYNSAYYEHAFLAQQMGIH 295 + D +R + Sbjct: 198 AFNLNIYFDRAIEKDRLFGLSLDGHWITVGTP 257 Query: 296 LVEGRDLVAQDHKVYLKEMNGMXXXXXXXXXXXXXXXXXXAFQPNSLLGVAGLMNAYRAG 355 Sbjct: 258 317 Query: 356 NIAIANAPGTGVADDKAMYVYVPDMIRYY 384 Sbjct: 318 346 >Rv2411c [S] COG2308 Uncharacterized conserved protein Length = 551 Score = 267 bits (683), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 135/330 (40%), Positives = 193/330 (58%), Gaps = 6/330 (1%) Query: 57 YDEMYADERSIRPHYKHVNRMFSGMSPEEXXXXXXXXXXXXXXXGITFTLYNPAQDHPME 116 +DEM+ + +R YK + + E GITF+L E Sbjct: 38 FDEMFDAQGIVRGPYKGIYAELAPSDASELKARADALGRAFIDQGITFSLSG------QE 91 Query: 117 RTIPFDMIPRIIPKGEWERLEAGIVQRITALNLFIHDIYHEQFIVKDGIVPRRMIISNCY 176 R P D++PR+I EW RLE GI QR+ AL ++ DIY +Q I++DG++PRR++ S + Sbjct: 92 RPFPLDLVPRVISAPEWTRLERGITQRVKALECYLDDIYGDQEILRDGVIPRRLVTSCEH 151 Query: 177 FRPEMSGLRVPGGAYVTTSGIDLIRHHDGEYYVLEDNLRTPSGFSYLFKGRSLMNQLFPE 236 F + G+ P G + +GIDLIR H G++ VLEDNLR+PSG SY+ + R M ++FP Sbjct: 152 FHRQAVGIVPPNGVRIHVAGIDLIRDHRGDFRVLEDNLRSPSGVSYVMENRRTMARVFPN 211 Query: 237 LSLASSIRDVDHSLNRFLSVLRSLSPSRTKDPVIALLTPGEYNSAYYEHAFLAQQMGIHL 296 L +R VD + L LR+ + + DP + +LTPG YNSAY+EH+ LA+QMG+ L Sbjct: 212 LFATHRVRAVDDYASHLLRALRNSAATNEADPTVVVLTPGVYNSAYFEHSLLARQMGVEL 271 Query: 297 VEGRDLVAQDHKVYLKEMNGMXXXXXXXXXXXXXXXXXXAFQPNSLLGVAGLMNAYRAGN 356 VEGRDL +D++VY++ G F+ +S+LGVAGL+NA RAGN Sbjct: 272 VEGRDLFCRDNQVYMRTTEGERQVDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGN 331 Query: 357 IAIANAPGTGVADDKAMYVYVPDMIRYYLN 386 + +++A G GV DDK +Y YVP MI YYL+ Sbjct: 332 VVLSSAIGNGVGDDKLVYTYVPTMIEYYLH 361 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.141 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 28,072,428 Number of extensions: 1081005 Number of successful extensions: 1760 Number of sequences better than 1.0e-05: 14 Number of HSP's gapped: 1733 Number of HSP's successfully gapped: 14 Length of query: 412 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 303 Effective length of database: 25,807,025 Effective search space: 7819528575 Effective search space used: 7819528575 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 117 (49.7 bits)