BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0028.p (435 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2101 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 593 e-169 PA4588 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 441 e-124 STM1299 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 434 e-121 NMA1964 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 427 e-119 NMB1710 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 427 e-119 >BH2101 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 593 bits (1529), Expect = e-169, Method: Compositional matrix adjust. Identities = 0/432 (0%), Positives = 0/432 (0%) Query: 4 RDPHEREFHQAVKEILDTLVPVLARHPRYREHGILERMVEPERSITFRVPWVDDAGTIQV 63 E+ + +L + ++ +P Sbjct: 27 VPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIR 86 Query: 64 NRGYRIQFNSAIGPYKGGIRFHPSVYSGIIKFLGFEQIFKNALTXXXXXXXXXXXXXXXX 123 N + + L Q Sbjct: 87 NWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVA 146 Query: 124 XXXXQEIMRFTQSFMTELYRHIGPDSDVPAGDIGVGAREIGYMFGQYKRIRGGHEAGVLT 183 Y I ++ Sbjct: 147 WEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 184 GKGLQYGGSLARKEATGYGCVYFVQEMLAAKGLGFRDNRXXXXXXXXXXIYAIEKAQQMG 243 Sbjct: 207 266 Query: 244 ASVVACSDSGGYIYDPLGINLETVKRLKETQQLRISEYVKIHPHAEYFAGCAGIWNLPCD 303 Sbjct: 267 326 Query: 304 IALPCATQNELDEDAARKLINNGVKAIGEGANMPSTLQAIQLFLDNAVLFXXXXXXXXXX 363 Sbjct: 327 386 Query: 364 XXXXXLEMSQNSMRIAWTFEEVDEKLQSIMKNIYRSAVEAAEEYEVPGNLLAGANIAGFL 423 Sbjct: 387 446 Query: 424 RVADAMLAQGIV 435 Sbjct: 447 458 >PA4588 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 441 bits (1135), Expect = e-124, Method: Compositional matrix adjust. Identities = 0/436 (0%), Positives = 0/436 (0%), Gaps = 9/436 (2%) Query: 4 RDPHEREFHQAVKEILDTLVPVLARHPRYREHGILERMVEPERSITFRVPWVDDAGTIQV 63 A + + +L++ R A Sbjct: 15 ERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSA 74 Query: 64 NRGYRIQFNSAIGPYKGGIRFHPSVYSGIIKFLGFEQIFKNALTXXXXXXXXXXXXXXXX 123 + + + ++F + ++ Sbjct: 75 LPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNW 134 Query: 124 XXXXQEIMRFTQSFMTELYRHIGPDSDVPAGDIGVGAREIGYMFGQYKRIRGGHEAGVLT 183 +MR R P + V A + + Sbjct: 135 LEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSH-QAI 193 Query: 184 GKGLQYGGSLARKEATGYGCVYFVQEMLAAKGLGFRDNRXXXXXXXXXXIYAIEKAQQMG 243 Sbjct: 194 253 Query: 244 ASVVACSDSGGYIYDPLGINLETVKRLKETQQLRISEYVKIHPHAEYFA----GCAGIWN 299 Sbjct: 254 --- 310 Query: 300 LPCDIALPCATQNELDEDAARKLINNGVKAIGEGANMPSTLQAIQLFLDNAVLFXXXXXX 359 Sbjct: 311 370 Query: 360 XXXXXXXXXLEMSQNSMRIAWTFEEVDEKLQSIMKNIYRSAVEAAEEYEVPGNLLAGANI 419 Sbjct: 371 - 429 Query: 420 AGFLRVADAMLAQGIV 435 Sbjct: 430 445 >STM1299 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 434 bits (1115), Expect = e-121, Method: Compositional matrix adjust. Identities = 0/438 (0%), Positives = 0/438 (0%), Gaps = 7/438 (1%) Query: 1 VITRDPHEREFHQAVKEILDTLVPVLARHPRYREHGILERMVEPERSITFRVPWVDDAGT 60 P + E ++ + + I + +A + Sbjct: 14 AERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARS 73 Query: 61 IQVNRGYRIQFNSAIGPYKGGIRFHPSVYSGIIKFLGFEQIFKNALTXXXXXXXXXXXXX 120 + + P + + + +L Sbjct: 74 ALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDN 133 Query: 121 XXXXXXXQEIMRFTQSFMTELYRHIGPDSDVPAGDIGVGAREIGYMFGQYKRIRGGHEAG 180 + + R + E+ Y Sbjct: 134 WLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQM-PSHQA 192 Query: 181 VLTGKGLQYGGSLARKEATGYGCVYFVQEMLAAKGLGFRDNRXXXXXXXXXXIYAIEKAQ 240 ++ + ++ + + + + Sbjct: 193 IIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME 252 Query: 241 QMGASVVACSDSGGYIYDPLGINLETVKRL---KETQQLRISEYVKIHPHAEYFAGCAGI 297 Sbjct: 253 -- 310 Query: 298 WNLPCDIALPCATQNELDEDAARKLINNGVKAIGEGANMPSTLQAIQLFLDNAVLFXXXX 357 Sbjct: 311 370 Query: 358 XXXXXXXXXXXLEMSQNSMRIAWTFEEVDEKLQSIMKNIYRSAVEAAEEYEVPGNLLAGA 417 Sbjct: 371 - 429 Query: 418 NIAGFLRVADAMLAQGIV 435 Sbjct: 430 447 >NMA1964 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 427 bits (1098), Expect = e-119, Method: Compositional matrix adjust. Identities = 0/435 (0%), Positives = 0/435 (0%), Gaps = 8/435 (1%) Query: 4 RDPHEREFHQAVKEILDTLVPVLARHPRYREHGILERMVEPERSITFRVPWVDDAGTIQV 63 + + L+ + V L + P IT + Sbjct: 14 AERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARS 73 Query: 64 NRGYRIQFNSAIGPYKGGIRFHPSVYSGIIKFLGFEQIFKNALTXXXXXXXXXXXXXXXX 123 + I ++ + +++L L Sbjct: 74 ALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDN 133 Query: 124 XXXXQEIMRFTQSFMTELYRHIGPDSDVPAGDIGVGAREIGYMFGQYKRIRGGHEAGVLT 183 ++ ++ + + + + Sbjct: 134 WLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPS-HQA 192 Query: 184 GKGLQYGGSLARKEATGYGCVYFVQEMLAAKGLGFRDNRXXXXXXXXXXIYAIEKAQQMG 243 L + + L + A++M Sbjct: 193 IIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME 252 Query: 244 ASVVACSDSGGYIYDPLG----INLETVKRLKETQQLRISEYVKIHPHAEYFAGCAGIWN 299 Sbjct: 253 -- 310 Query: 300 LPCDIALPCATQNELDEDAARKLINNGVKAIGEGANMPSTLQAIQLFLDNAVLFXXXXXX 359 Sbjct: 311 370 Query: 360 XXXXXXXXXLEMSQNSMRIAWTFEEVDEKLQSIMKNIYRSAVEAAEEYEVPGNLLAGANI 419 Sbjct: 371 - 429 Query: 420 AGFLRVADAMLAQGI 434 Sbjct: 430 444 >NMB1710 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 427 bits (1097), Expect = e-119, Method: Compositional matrix adjust. Identities = 0/435 (0%), Positives = 0/435 (0%), Gaps = 8/435 (1%) Query: 4 RDPHEREFHQAVKEILDTLVPVLARHPRYREHGILERMVEPERSITFRVPWVDDAGTIQV 63 + + L+ + V L + P IT + Sbjct: 14 AERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARS 73 Query: 64 NRGYRIQFNSAIGPYKGGIRFHPSVYSGIIKFLGFEQIFKNALTXXXXXXXXXXXXXXXX 123 + I ++ + +++L L Sbjct: 74 ALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDN 133 Query: 124 XXXXQEIMRFTQSFMTELYRHIGPDSDVPAGDIGVGAREIGYMFGQYKRIRGGHEAGVLT 183 ++ ++ + + + + Sbjct: 134 WLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPS-HQA 192 Query: 184 GKGLQYGGSLARKEATGYGCVYFVQEMLAAKGLGFRDNRXXXXXXXXXXIYAIEKAQQMG 243 L + + L + A++M Sbjct: 193 IIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME 252 Query: 244 ASVVACSDSGGYIYDP----LGINLETVKRLKETQQLRISEYVKIHPHAEYFAGCAGIWN 299 Sbjct: 253 -- 310 Query: 300 LPCDIALPCATQNELDEDAARKLINNGVKAIGEGANMPSTLQAIQLFLDNAVLFXXXXXX 359 Sbjct: 311 370 Query: 360 XXXXXXXXXLEMSQNSMRIAWTFEEVDEKLQSIMKNIYRSAVEAAEEYEVPGNLLAGANI 419 Sbjct: 371 - 429 Query: 420 AGFLRVADAMLAQGI 434 Sbjct: 430 444 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.139 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 28,672,764 Number of extensions: 1078626 Number of successful extensions: 2337 Number of sequences better than 1.0e-05: 33 Number of HSP's gapped: 2230 Number of HSP's successfully gapped: 33 Length of query: 435 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 326 Effective length of database: 25,807,025 Effective search space: 8413090150 Effective search space used: 8413090150 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 117 (49.7 bits)