BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0004.p (341 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO0611 [K] COG1609 Transcriptional regulators 229 3e-60 RSc1014 [K] COG1609 Transcriptional regulators 229 5e-60 PM0547 [K] COG1609 Transcriptional regulators 217 2e-56 VC1721 [K] COG1609 Transcriptional regulators 212 7e-55 HI1635 [K] COG1609 Transcriptional regulators 207 2e-53 >YPO0611 [K] COG1609 Transcriptional regulators Length = 328 Score = 229 bits (585), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 124/328 (37%), Positives = 193/328 (58%), Gaps = 4/328 (1%) Query: 11 TIKDVAKLAGVALSTASYAMSGDSKVSAKTREKVLEAARQLNYQKNGFAMDLKRSRTNTI 70 TIKDVAK A V++ST SYA++G K++ +TR +VL+ A+++NY N A LK ++ I Sbjct: 4 TIKDVAKRAKVSISTVSYAINGSPKITEETRLRVLKIAQEMNYTANNNAKMLKAKKSGAI 63 Query: 71 ALILTDLSGPYYSELIRSIQDVALSNSYDLIACSSMGGKDSTAVRFLLEKRVDGAIVLAH 130 L GP YSEL+R I++ YDL+ACS GG+ STA ++L ++ VDGAI+L Sbjct: 64 GLFFNSWFGPVYSELVRGIEERVHREHYDLVACSLYGGEQSTAHKYLRDRSVDGAIILTS 123 Query: 131 NITDEILQAAGSSRFPIVVMDRLIAGEGLINVVVDGELGGYSATRYLIDKGHQHIAYISG 190 + D LQ+ S PIVV+DR + + NV++D G + A L+ KG + I + SG Sbjct: 124 SFDDRFLQSVASDVLPIVVLDRELKSPHIYNVLIDNFGGAFKAVNALLAKGCRDIYFFSG 183 Query: 191 PANSYDNALRYKGFMRAMHEAGLEEKAKWKLNGGGFXXXXGYKSTKMMLMQGELPSAIFY 250 P SYDN R GF+ A+ ++ + ++ F Y + ++ G +PSAIF Sbjct: 184 PEQSYDNQKRLDGFIAALGYHNIQLNRDFIIH-SNFTEADAYLKMQALIAAGRVPSAIFS 242 Query: 251 ANDEMAVGGMKALEEGGISVPEDISVIGFDDIQLAEYIQPPLTTIRQXXXXXXSGSLASH 310 ANDEMA+G ++A +E I VP+D+ V+GFD+I + + P LTTI G ++++ Sbjct: 243 ANDEMAIGILRAAKEHNIRVPDDLKVVGFDNIYASSVLTPSLTTINHHKYEM--GVISAN 300 Query: 311 LLFQMLNGDT-VNDFYKLKIELVERQSV 337 L + + +T ++ L EL+ER+++ Sbjct: 301 TLLRAIKEETNIDAVTLLPTELIERETL 328 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 229 bits (584), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 130/335 (38%), Positives = 194/335 (57%), Gaps = 7/335 (2%) Query: 9 MATIKDVAKLAGVALSTASYAMSGDSKVSAKTREKVLEAARQLNYQKNGFAMDLKRSRTN 68 MATIKDVA LAGV+ +T S+ ++ V+++TR++V EA R Y + A LK T Sbjct: 1 MATIKDVAALAGVSFTTVSHVINNTRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTR 60 Query: 69 TIALILTDLSGPYYSELIRSIQDVALSNSYDLIACSSMGG--KDSTAVRFLLEKRVDGAI 126 TI +++ + PY++EL R I+DV + Y +I C+S K +R L+EKRVDG I Sbjct: 61 TIGVLVPTATNPYFAELARGIEDVCAAAGYSVILCNSDDDPRKQRDYLRVLMEKRVDGLI 120 Query: 127 VLAHNITDEILQAAGSSRFPIVVMDRLIAGEGLINVVVDGELGGYSATRYLIDKGHQHIA 186 V + + +L A G S P+V++DR G V +D E G Y ATR+L++ GH+ IA Sbjct: 121 VSSAGPDNALLDALGESALPVVMVDRPTEGILADQVQIDHEEGAYLATRHLLELGHRRIA 180 Query: 187 YISGPANSYDNALRYKGFMRAMHEAGLEEKAKWKLNGGGFXXXXGYKSTKMMLMQGELPS 246 ISGP+ A R GF RA+ EAG+ E A ++ G F GY++ + +L GE P+ Sbjct: 181 CISGPSTLSVTAGRLAGFHRALREAGVPEHA-ARVAEGDFTSPGGYRAARELLTTGETPT 239 Query: 247 AIFYANDEMAVGGMKALEEGGISVPEDISVIGFDDIQLAEYIQPPLTTIRQXXXXXXSGS 306 AIF +ND M +G ++A E GI+VP+++S+IGFDDI+L+ Y+ P L+T+ Q G Sbjct: 240 AIFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQL--GE 297 Query: 307 LASHLLFQMLNGDTVNDFYKLKIELVERQSVLPQK 341 + L + L + +I R+ VLP + Sbjct: 298 TTASTLLEHLTDHAARHHH--EIPDAPRRIVLPPR 330 >PM0547 [K] COG1609 Transcriptional regulators Length = 334 Score = 217 bits (552), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 126/334 (37%), Positives = 192/334 (57%), Gaps = 9/334 (2%) Query: 9 MATIKDVAKLAGVALSTASYAMSGDSKVSAKTREKVLEAARQLNYQKNGFAMDLKRSRTN 68 MATIKDVAK+AGV+ +T S+ ++ V+A+T + VL+A ++LNY + A LK + T Sbjct: 1 MATIKDVAKMAGVSTTTVSHVINKTRFVAAETEKLVLQAIQELNYSPSAVARSLKVNTTK 60 Query: 69 TIALILTDLSGPYYSELIRSIQDVALSNSYDLIACSSMGG--KDSTAVRFLLEKRVDGAI 126 +I +I+T PY++E+I ++++ Y L C++ K + L++KRVDG + Sbjct: 61 SIGMIVTSSEAPYFAEIIHAVEEHCYRQGYSLFLCNTQNNVEKIKNHLEMLIKKRVDGIL 120 Query: 127 VLAHNITDEILQ-AAGSSRFPIVVMDRLIAGEGLINVVVDGEL-GGYSATRYLIDKGHQH 184 V+ T + L A + P+VVMD +++ D GGY AT+YLID GH+ Sbjct: 121 VMCAEYTQDSLDLLANFTSLPLVVMD-WGPDNKHTDIIQDHSFEGGYLATKYLIDHGHKD 179 Query: 185 IAYISGPANSYDNALRYKGFMRAMHEAGLEEKAKWKLNGGGFXXXXGYKSTKMMLMQGEL 244 I I+G RY+GF++AM+EAGL+ W + G F GY+ +L Q L Sbjct: 180 IGIIAGELTKTTAKTRYEGFIKAMNEAGLKINPDWVME-GFFEPEDGYECMNKILAQDTL 238 Query: 245 PSAIFYANDEMAVGGMKALEEGGISVPEDISVIGFDDIQLAEYIQPPLTTIRQXXXXXXS 304 P+A+F ND MA+G + A+ E G+ VPEDIS+IG+D+I + + PPLTTI Q Sbjct: 239 PTAVFCCNDVMALGAISAIGEKGLRVPEDISIIGYDNIHASRFYSPPLTTIHQSKSRL-- 296 Query: 305 GSLASHLLFQMLNGDTVND-FYKLKIELVERQSV 337 G+ A LLF+ +N + ++ ELV R+SV Sbjct: 297 GARAVTLLFERINEKSEERAVIEMHPELVIRKSV 330 >VC1721 [K] COG1609 Transcriptional regulators Length = 336 Score = 212 bits (540), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 123/332 (37%), Positives = 186/332 (56%), Gaps = 5/332 (1%) Query: 9 MATIKDVAKLAGVALSTASYAMSGDSKVSAKTREKVLEAARQLNYQKNGFAMDLKRSRTN 68 MATIKDVA+LAGV+ +T S+ ++ V+ T+EKV+EA +QLNY + A LK + T Sbjct: 1 MATIKDVARLAGVSTTTVSHVINKTRFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTR 60 Query: 69 TIALILTDLSGPYYSELIRSIQDVALSNSYDLIACSSMG--GKDSTAVRFLLEKRVDGAI 126 TI +++T + ++SE+I ++ Y LI C++ G K +R L EKRVDG + Sbjct: 61 TIGMLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDGIL 120 Query: 127 VLAHNITDEILQAAGSSR-FPIVVMDRLIAGEGLINVVVDGELGGYSATRYLIDKGHQHI 185 V+ ++T E+ + + P VVMD ++ + E GGY AT+YL D+GH I Sbjct: 121 VMCSDLTQELQDMLDAHKDIPKVVMDWGPETSHADKIIDNSEEGGYLATKYLTDRGHTEI 180 Query: 186 AYISGPANSYDNALRYKGFMRAMHEAGLEEKAKWKLNGGGFXXXXGYKSTKMMLMQGELP 245 A +SG R +GF RAM EA L W L G F + ++ + P Sbjct: 181 ACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWILE-GNFECDTAVLAADKIIAMDKRP 239 Query: 246 SAIFYANDEMAVGGMKALEEGGISVPEDISVIGFDDIQLAEYIQPPLTTIRQXXXXXXSG 305 +A+F ND MA+G M L++ GI +PED+SVIG+D+I+LAEY PPLTT+ Q Sbjct: 240 TAVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKRRVGKN 299 Query: 306 SLASHLLFQMLNGDTVNDFYKLKIELVERQSV 337 + LL ++ + + +++ E+VER +V Sbjct: 300 AFEI-LLERIKDKEHERRIFEMHPEIVERDTV 330 >HI1635 [K] COG1609 Transcriptional regulators Length = 336 Score = 207 bits (528), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 128/338 (37%), Positives = 184/338 (54%), Gaps = 15/338 (4%) Query: 9 MATIKDVAKLAGVALSTASYAMSGDSKVSAKTREKVLEAARQLNYQKNGFAMDLKRSRTN 68 MATIKDVAK+AGV+ +T S+ ++ V+ T E VL A +QLNY + A LK + T Sbjct: 1 MATIKDVAKMAGVSTTTVSHVINKTRFVAKDTEEAVLSAIKQLNYSPSAVARSLKVNTTK 60 Query: 69 TIALILTDLSGPYYSELIRSIQDVALSNSYDLIACSSM--GGKDSTAVRFLLEKRVDGAI 126 +I +I+T PY++E+I S+++ Y L + K + L +KRVDG + Sbjct: 61 SIGMIVTTSEAPYFAEIIHSVEEHCYRQGYSLFCVTHKMDPEKVKNHLEMLAKKRVDGLL 120 Query: 127 VLAHNITDEILQAAGS-SRFPIVVMDRLIAGEGLINVVVDGEL--GGYSATRYLIDKGHQ 183 V+ T + L S S P+VVMD G V+D GGY AT++LI+ GH+ Sbjct: 121 VMCSEYTQDSLDLLSSFSTIPMVVMD---WGPNANTDVIDDHSFDGGYLATKHLIECGHK 177 Query: 184 HIAYISGPANSYDNALRYKGFMRAMHEAGLEEKAKWKLNGGGFXXXXGYKSTKMMLMQGE 243 I I G N RY+GF +AM EA L W L G F GY+ +L Q + Sbjct: 178 KIGIICGELNKTTARTRYEGFEKAMEEAKLTINPSWVLEGA-FEPEDGYECMNRLLTQEK 236 Query: 244 LPSAIFYANDEMAVGGMKALEEGGISVPEDISVIGFDDIQLAEYIQPPLTTIRQXXXXXX 303 LP+A+F ND MA+G + AL E G+ VPED+S+IG+DDI + + PPLTTI Q Sbjct: 237 LPTALFCCNDVMALGAISALTEKGLRVPEDMSIIGYDDIHASRFYAPPLTTIHQSKLRL- 295 Query: 304 SGSLASHLLFQMLN--GDTVNDFYKLKI--ELVERQSV 337 G A ++L + + + V + ++ I EL+ R+SV Sbjct: 296 -GRQAINILLERITHKDEGVQQYSRIDITPELIIRKSV 332 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,442,631 Number of extensions: 981693 Number of successful extensions: 3842 Number of sequences better than 1.0e-05: 178 Number of HSP's gapped: 3505 Number of HSP's successfully gapped: 179 Length of query: 341 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 234 Effective length of database: 26,037,693 Effective search space: 6092820162 Effective search space used: 6092820162 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)