BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0555.0007.p (289 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC2315 [M] COG1091 dTDP-4-dehydrorhamnose reductase 243 2e-64 CAP0122 [M] COG1091 dTDP-4-dehydrorhamnose reductase 216 4e-56 alr4490 [M] COG1091 dTDP-4-dehydrorhamnose reductase 209 5e-54 RSc0683 [M] COG1091 dTDP-4-dehydrorhamnose reductase 163 4e-40 FN1698 [M] COG1091 dTDP-4-dehydrorhamnose reductase 154 1e-37 >CAC2315 [M] COG1091 dTDP-4-dehydrorhamnose reductase Length = 346 Score = 243 bits (621), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 16/282 (5%), Positives = 44/282 (15%), Gaps = 7/282 (2%) Query: 4 MKVLVTGSAXXXXXXXXXXXXXXXHEVLGCDRQEMDITDLDQCVEIIGGFAPDAVIHCAA 63 M+ + + D + Q + +I V Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 64 HTAVDVAETDIDAAYLINATGSRNVALAAEKAGAKLVYISTDYVFDGMGTQPYHEYDNTD 123 + A + + + + I D D + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 124 PQSIYGKSKRAGEVLVQSLSSKFFIVRTSWVYGKYGNNFVKTMLKLGQEKPLLQVVDDQK 183 Q+ Y + + + + ++ Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPA-VSLLDTLDALAEYQRAGKIRYIGVS 179 Query: 184 GSPTYTVDLANFLLELIQTEKYGIYHASNTEFCTWYEFTQAIFAEAEDILGLKFTAKLEP 243 + V L + + + +E A + L Sbjct: 180 NETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVS----QYEGV--ELLAY 233 Query: 244 CSTEQFPRPAPRPQYSVMEHLAIRTNGFQDIRPWREGLRDFL 285 + + + Sbjct: 234 SCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVA 275 >CAP0122 [M] COG1091 dTDP-4-dehydrorhamnose reductase Length = 346 Score = 216 bits (549), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 10/238 (4%), Positives = 37/238 (15%), Gaps = 8/238 (3%) Query: 49 IIGGFAPDAVIHCAAHTAVDVAETDIDAAYLINATGSRNVALAAEKAGAKLVYISTDYVF 108 I + + ++ DA ++ ++ + L + Sbjct: 5 RIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 109 DGMGTQPYHEYDNTDPQSIYGKSKRAGEVLVQSLSSKFFIVRTSWVYGKYGNNFVKTMLK 168 + + + I + + ++ + Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 169 LGQEKPLLQVVDDQKGSPTYTVDLANFLLELIQTEKYGIYHASNTEFCTWYEFTQAIFAE 228 + + + + Y Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIG------- 177 Query: 229 AEDILGL-KFTAKLEPCSTEQFPRPAPRPQYSVMEHLAIRTNGFQDIRPWREGLRDFL 285 + + + YS++ E L Sbjct: 178 VSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSC 235 >alr4490 [M] COG1091 dTDP-4-dehydrorhamnose reductase Length = 346 Score = 209 bits (531), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 15/238 (6%), Positives = 37/238 (15%), Gaps = 5/238 (2%) Query: 28 HEVLGCDRQEMDITDLDQCVEIIGGFAPDAVIHCAAHTAVDVAETDIDAAYLINATGSRN 87 ++D I + + A + Sbjct: 26 QNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIA 85 Query: 88 VALAAEKAGAKLVYISTDYVFDGMGTQPYHEYDNTDPQSIYGKSKRAGEVLVQSLSSKFF 147 ++ + + H+ + + K Sbjct: 86 SKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLG 145 Query: 148 IVRTSWVYGKYG-NNFVKTMLKLGQEKPLLQVVDDQKGSPTYTVDLANFLLELIQT--EK 204 T + K V ++ +L + + Sbjct: 146 YSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQ 205 Query: 205 YGIYHASNTEFCTWYEFTQAIFAEAEDILGLKFTA-KLEPCSTEQFPRPAPRPQYSVM 261 + + E +Q E P A +S Sbjct: 206 NPYSLLNRSFEVGLAEVSQYEGVELLA-YSCLGFGTLTGKYLNGAKPAGARNTLFSRF 262 >RSc0683 [M] COG1091 dTDP-4-dehydrorhamnose reductase Length = 346 Score = 163 bits (412), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 20/299 (6%), Positives = 47/299 (15%), Gaps = 14/299 (4%) Query: 2 PKMKVLVTGSAXXXXXXXXXXXXXXXHEVLGCDRQEMDITDLDQCVEIIGGFAPDAVIHC 61 P + V+ I +D P+ Sbjct: 7 PHSSLEVSTL-GLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLT 65 Query: 62 AAHTAVDVAETDIDAAYLINATGSRNVALAAEKAGAKLVYISTDYVFDGMGTQPYHEYDN 121 + +A+ +I + S + + + + D Sbjct: 66 ETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDY 125 Query: 122 TDPQSIYGKSKRAGEVLVQSLSSKFFIVRTSWVYGKYGNNFVKTMLKLGQEKPLLQVVDD 181 D ++ + S S + + K+ + Sbjct: 126 LDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFG 185 Query: 182 QKGSPTYTVDLANFLLELI---------QTEKYGIYHASNTEFCTWYEFTQAIFAEAEDI 232 + I E + Sbjct: 186 VMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTG-K 244 Query: 233 LGLKFTA---KLEPCSTEQFPRPAPRPQYSVMEHLAIRTNGFQDIRPWREGLRDFLFEL 288 + S + R +G + +R F Sbjct: 245 YLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVA 303 >FN1698 [M] COG1091 dTDP-4-dehydrorhamnose reductase Length = 484 Score = 154 bits (390), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 13/275 (4%), Positives = 41/275 (14%), Gaps = 24/275 (8%) Query: 31 LGCDRQEMDITDLDQCVEIIG----GFAPDAVIHCAAHTAVDVAETDIDAAYLINATGSR 86 + IT + E P + T + + Sbjct: 27 ALRNAIGNYITSGELPDENARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTT 86 Query: 87 NVALAAEKAGAKLVYISTDYVFDGMGTQ-------PYHEYDNTDPQSIYGKSKRAGEVLV 139 ++ + + PY + ++ Sbjct: 87 ITRPTLFRSYLNEQLTLLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYF 146 Query: 140 QSL------SSKFFIVRTSWVYGKYGNNFVKTMLKLGQEKPLLQVVDDQKGSPTYTVDLA 193 + + + + + + + P Sbjct: 147 PTTELAQIGDETADGIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNY 206 Query: 194 NFLLELIQTE-KYGIYHASNTEFCTWYEFTQAIFAEAEDILGLKFTAKLEPCSTEQFPRP 252 ++ I + I AE + + + + Sbjct: 207 TRYVDEFVRWGCSQILDPDSPYIALSCAGGNWITAE------TEAPEEAISDLAWKKHQM 260 Query: 253 APRPQYSVMEHLAIRTNGFQDIRPWREGLRDFLFE 287 + N + Sbjct: 261 PAWHLITADGQGITLVNIGVGPSNAKTICDHLAVL 295 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,029,977 Number of extensions: 812830 Number of successful extensions: 2086 Number of sequences better than 1.0e-05: 23 Number of HSP's gapped: 2101 Number of HSP's successfully gapped: 23 Length of query: 289 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 184 Effective length of database: 26,268,361 Effective search space: 4833378424 Effective search space used: 4833378424 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)