BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0554.0012.p (608 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1879 [KT] COG3829 Transcriptional regulator containing PAS, AA... 273 6e-73 CAC0459 [KT] COG3829 Transcriptional regulator containing PAS, A... 273 6e-73 aq_2185 [K] COG1309 Transcriptional regulator 261 2e-69 BH3899 [KT] COG3829 Transcriptional regulator containing PAS, AA... 260 4e-69 RSp1667 [T] COG2204 Response regulator containing CheY-like rece... 260 4e-69 >BH1879 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Length = 555 Score = 273 bits (698), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 155/395 (39%), Positives = 223/395 (56%), Gaps = 21/395 (5%) Query: 217 EVDLESVFAGERNLSYADCTLTVGSNKIDCMVNIYPFTFDDKILGASLTIREAGQVRKEV 276 ++D+ +VF S+ + + + V I P +++ + ++KE Sbjct: 178 KIDVTNVFKP----SFQTVEMKLEGKREKWHVQIKPTYVQGEVVSFMIKF-----LKKET 228 Query: 277 NQLAGFK-ANYRFAEVITDNSYMQGQIAFAQRIAKTNCTVLIEGESGTGKELFAQSVHNA 335 NQ K Y F ++I + + A+RIA + T+L+ GESGTGKE+FAQ+VH Sbjct: 229 NQFKQSKDLLYSFQDIIGSSEAIHFAREMARRIAGQDITILLRGESGTGKEMFAQAVHRE 288 Query: 336 SLRAGGPFIAINCAALPKDLVESELFGYEKGSFTGALREGNPGKFELAHGGTIFLDEIGE 395 S RA GPF+AINCAA+P +L+ESELFGYE G+FTGA R+G G+FELAHGGTIFLDEIG+ Sbjct: 289 SQRAQGPFVAINCAAIPDNLLESELFGYESGAFTGAQRQGKAGRFELAHGGTIFLDEIGD 348 Query: 396 LPLEIQAKLLRVLDNHKVRRIGGKHERTLDVRVIAATNRDLAEEVDRKSYRSDLYYRLNV 455 + L +QAKLLRVL KV R+GG +DVR+IAAT+R+L E V +K++R DLYYRLNV Sbjct: 349 MSLHLQAKLLRVLQERKVERVGGTQSVYVDVRIIAATHRNLEEMVQKKTFREDLYYRLNV 408 Query: 456 INIKLLPLRERREDIAPLARLFLLKCNRDHPGPAKRFSPSFLEALQSYEWQGNARELQNA 515 I I + P+RER+ED+ L F+ + + K FS + + Y W GN RE+ N Sbjct: 409 IPITIPPVRERKEDLPILIEYFMKRLSNKEKKQPKYFSKDAYDLIFRYPWPGNVREIVNM 468 Query: 516 VQRAYYVCSSAEITHLDLPPARTSLLQHSNSGNAAVPEKPSAEGAGKKMEQIEMESICSA 575 V+ Y+ + IT D PA + + ++ + P E + K + + Sbjct: 469 VEHVIYLETGDLIT-ADSLPAYLKIKEGKSTSQLQINVAPHGEESFK-------QQVLHL 520 Query: 576 LKTCGGNV---VTAAKMLGIGKSTMYRKIAGYGIR 607 L G + AK +GI T+YR++ IR Sbjct: 521 LDVYGRHTEGKKRIAKEMGISLPTLYRRLKKLKIR 555 >CAC0459 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Length = 627 Score = 273 bits (698), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 163/462 (35%), Positives = 259/462 (56%), Gaps = 24/462 (5%) Query: 154 SIEKQLHMLEA-------SQMMHAVFQSMQDGLLVIDTEYRVRHYNERLASIFMLSLEQM 206 +IE+ L+++E S A+ ++ +G++V D ++ YN + IF + ++ Sbjct: 174 AIEEALNLIEVRNIELRRSARFKAILDAIGEGIIVTDQFKKIITYNNSINKIFTKTGSKL 233 Query: 207 ETLRIKELLEEVDLESVFAGERNLSYADCTLTVGSNKIDCMVNIYPFTFDDKILGASLTI 266 I+ ++ ++S+ +N+ + + N + +P +DKI+G T Sbjct: 234 LGKSIQSVIPNYKVDSIL---KNVE-PETKIIKNFNGLIIAAKQFPVKLEDKIIGVVNTF 289 Query: 267 REAGQV-------RKEVNQLAGFKANYRFAEVITDNSYMQGQIAFAQRIAKTNCTVLIEG 319 + ++ RK++++ GF A Y F +++T + M A +KT+ ++LI+G Sbjct: 290 EDVTKIQTLEKIIRKKIHE-KGFVAKYNFDDILTQDKNMIELKKLALLYSKTDSSILIQG 348 Query: 320 ESGTGKELFAQSVHNASLRAGGPFIAINCAALPKDLVESELFGYEKGSFTGALREGNPGK 379 ESG+GKELFAQS+HN+S R GPF+AINCAALP+ L+ESELFGYE GSFTGA +EG G Sbjct: 349 ESGSGKELFAQSIHNSSPRKNGPFVAINCAALPEHLLESELFGYEGGSFTGAKKEGKQGL 408 Query: 380 FELAHGGTIFLDEIGELPLEIQAKLLRVLDNHKVRRIGGKHERTLDVRVIAATNRDLAEE 439 FELAH GTIFLDEIGEL +QA+LLRVL+ ++ IGG +D+R+I++TNR+L Sbjct: 409 FELAHNGTIFLDEIGELSKPLQAQLLRVLEEKEIMHIGGDKIIPVDIRIISSTNRNLLNS 468 Query: 440 VDRKSYRSDLYYRLNVINIKLLPLRERREDIAPLARLFLLKCNRDHPGPAKRFSPSFLEA 499 ++ ++R DLYYRLNV N+ L PLRER +DI LA FL + +K + Sbjct: 469 IENGTFREDLYYRLNVFNLTLPPLRERGKDIEILAEHFLENTHNFSSNRSKILN-QITPF 527 Query: 500 LQSYEWQGNARELQNAVQR-AYYVCSSAEITHLDLPPARTSLLQHSNSGNAAVPEKPSAE 558 L +Y W GN REL N ++R + ++ +S I + ++ + + P Sbjct: 528 LMAYNWPGNTRELSNVMERISLFIENSMTI---NWSQVLYKVVHKEKIEDTLTLKVPYNL 584 Query: 559 GAGKKMEQIEMESICSALKTCGGNVVTAAKMLGIGKSTMYRK 600 + +E E I S L+ + A++L IG++T++RK Sbjct: 585 TMKEIIELTEKRVIHSLLERYDNDHNRVAEILNIGRTTLWRK 626 >aq_2185 [K] COG1309 Transcriptional regulator Length = 506 Score = 261 bits (668), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 137/306 (44%), Positives = 189/306 (61%), Gaps = 10/306 (3%) Query: 302 IAFAQRIAKTNCTVLIEGESGTGKELFAQSVHNASLRAGGPFIAINCAALPKDLVESELF 361 + R+A TN TVL+ GESG GKE+FA+++H S RA PF+AINC A+P +L+E+ELF Sbjct: 206 LEIVHRVAPTNATVLLRGESGVGKEVFARAIHFLSPRADKPFVAINCGAIPGELLEAELF 265 Query: 362 GYEKGSFTGALREGNPGKFELAHGGTIFLDEIGELPLEIQAKLLRVLDNHKVRRIGGKHE 421 GYEKG+FTGA GKFELA+GGT+FLDEIGELPL +Q KLLR + ++ RIGG Sbjct: 266 GYEKGAFTGAY-STKKGKFELANGGTLFLDEIGELPLHLQVKLLRAIQEKEIERIGGTRP 324 Query: 422 RTLDVRVIAATNRDLAEEVDRKSYRSDLYYRLNVINIKLLPLRERREDIAPLARLFLLKC 481 +DVR+IAATNRDL V +R DLYYRLNV+ I + PLRER+EDI L FL K Sbjct: 325 IKVDVRIIAATNRDLESMVREGKFREDLYYRLNVVPIFIPPLRERKEDIPVLVHYFLEKF 384 Query: 482 NRDHPGPAKRFSPSFLEALQSYEWQGNARELQNAVQRAYYVCSSAEITHLDLPPARTSLL 541 ++++ + ++A YEW+GN RELQN ++R + + ++ DLPP + Sbjct: 385 SKEYNKEVS-ITQEVMDAFMKYEWKGNVRELQNVLERMVILDTDGVLSEEDLPPEIRDVK 443 Query: 542 QHSNSGNAAVPEKPSAEGAGKKMEQIEMESICSALKTCGGNVVTAAKMLGIGKSTMYRKI 601 + S N + G+ + +E + I AL+ G + AAK LG+ + +I Sbjct: 444 KESRIYNQTL--------NGETIWDLEKQLIEKALEESGFVIKEAAKKLGMTPRQVSYRI 495 Query: 602 AGYGIR 607 YGI+ Sbjct: 496 QKYGIK 501 >BH3899 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Length = 559 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 179/487 (36%), Positives = 261/487 (53%), Gaps = 38/487 (7%) Query: 133 LSGKAEDVHAHTF-GVVVSAVSSIEKQLHMLEASQMMHAVFQSMQDGLLVIDTEYRVRHY 191 LSG D++ T G + + Q+ +LEA MM F DGL+++D E + Sbjct: 87 LSGDEVDLYLLTLEGETDEFLHVNDHQVELLEA--MMEFAF----DGLVMVDREGYITAL 140 Query: 192 NERLASIFMLSLEQMETLRIKELLEEVDLESVFAGERNLSYADCTLTVGSNKIDCMVNIY 251 + AS ++ E+ + E++E + + A A+ G I V Sbjct: 141 STDYASFLGVNQEEAIGKHVTEVIENTRMH-IVAKSGKTEVAELQKIRGDYMIATRV--- 196 Query: 252 PFTFDDKILGASLTI------------REAGQVRKEVNQLAG-----FKANYRFAEVITD 294 P + ++ GA + + + KE+ + G KA Y+F+ +I Sbjct: 197 PIIKNGQVTGAVGKVLFKNVGGFNSLYKRVNSMEKELKRYKGEMKELNKAAYQFSNIIGS 256 Query: 295 NSYMQGQIAFAQRIAKTNCTVLIEGESGTGKELFAQSVHNASLRAGGPFIAINCAALPKD 354 + + A++ AK++ VL+ GESGTGKELFA S+HN S RA G F+ +NCAA+P D Sbjct: 257 SPLLVQAKKEAKKAAKSDSNVLLLGESGTGKELFAHSIHNESRRAFGSFVKVNCAAIPAD 316 Query: 355 LVESELFGYEKGSFTGALREGNPGKFELAHGGTIFLDEIGELPLEIQAKLLRVLDNHKVR 414 L+ESELFGYE+GSFTGA++ G GKFE A GGTIFLDEIGELPL +Q K LRVL +V Sbjct: 317 LLESELFGYEEGSFTGAIKGGKKGKFEAADGGTIFLDEIGELPLHMQVKFLRVLQEKEVE 376 Query: 415 RIGGKHERTLDVRVIAATNRDLAEEVDRKSYRSDLYYRLNVINIKLLPLRERREDIAPLA 474 +IG +++DVRVIAATNRDL + V +R DLYYRLNV+ I + LR+R+ DI LA Sbjct: 377 KIGSSTGKSVDVRVIAATNRDLEKMVQAGEFRLDLYYRLNVMPITVPSLRDRKGDIPRLA 436 Query: 475 RLFLLKCNRDHPGPAKRFSPSFLEALQSYEWQGNARELQNAVQRAYYVCSSAEITHLDLP 534 R FL K A+ P + AL+ YEW GN REL+N ++RA V + ++ Sbjct: 437 RYFLEKYRERMNMVARDIHPEAILALEQYEWPGNIRELENVIERAVNVAENEKMIRRCHL 496 Query: 535 PARTSLLQHSNSGNAAVPEKPSAEGAGKKMEQIEMESICSALKTCGGNVVTAAKMLGIGK 594 P + + +Q + + ME+ E E+I +AL+ N AA +L I + Sbjct: 497 PEKITGVQF----------RSGVRPLEQVMEETEKEAILNALRVTNNNRTKAANLLQISR 546 Query: 595 STMYRKI 601 +++Y K+ Sbjct: 547 TSLYEKM 553 >RSp1667 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Length = 491 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 162/399 (40%), Positives = 229/399 (57%), Gaps = 21/399 (5%) Query: 213 ELLEEVDLES-----VFAGERNLSYADCTLTVGSNKIDCMVNIYPFTFDDKILGASLTIR 267 +LLE++ S V G ++ A L +G+ D +V F IL I Sbjct: 92 DLLEDIPSHSGTEIIVMTGHASVETAVEALRMGA--ADYLVKPVNFQRLKSILA---RIP 146 Query: 268 EAGQVRKEVNQLAG-FKANYRFAEVITDNSYMQGQIAFAQRIAKTNCTVLIEGESGTGKE 326 G ++ E+ L G + F +++ ++ MQ R+A T TVL+ GESGTGKE Sbjct: 147 RPGDLKAEIGSLRGELRRLGLFGQMLGNSPAMQTLYDQVSRVAPTEATVLLIGESGTGKE 206 Query: 327 LFAQSVHNASLRAGGPFIAINCAALPKDLVESELFGYEKGSFTGALREGNPGKFELAHGG 386 L AQ++H+ SLR PF+ +NC A+ +L+ESE+FG+E+GSFTGA R+ + G FE A+GG Sbjct: 207 LAAQTIHDLSLRRKQPFLPVNCGAISPNLIESEMFGHERGSFTGADRQ-HKGYFERANGG 265 Query: 387 TIFLDEIGELPLEIQAKLLRVLDNHKVRRIGGKHERTLDVRVIAATNRDLAEEVDRKSYR 446 T+FLDEI E+P+E+Q KLLRVL+ R+G E DVRVIAATNRD E V R Sbjct: 266 TLFLDEITEMPVELQVKLLRVLETGVFMRVGTNREIDTDVRVIAATNRDPEEAVADGKLR 325 Query: 447 SDLYYRLNVINIKLLPLRERREDIAPLARLFLLKCNRDHPGPAKRFSPSFLEALQSYEWQ 506 +DLY+RLNV ++L PLRER +D+ LA+ FL + N + K F P ++ L++Y W Sbjct: 326 ADLYHRLNVFPMQLPPLRERGKDVELLAQHFLDQLNAQN-SSKKTFLPPAMDTLRAYNWP 384 Query: 507 GNARELQNAVQRAYYVCSSAEITHLDLPPARTSLLQHSNSGNAAVPEKPSAEGAGKKMEQ 566 GN REL+N VQRAY + A I+ + P + S Q S+ +P S A KK+ Sbjct: 385 GNVRELRNYVQRAYIMSDDAGIS-TEAVPLQVSTTQASSGSTLTIPVGTSLASADKKI-- 441 Query: 567 IEMESICSALKTCGGNVVTAAKMLGIGKSTMYRKIAGYG 605 I + L+ CGG AA++LGI T+Y ++ YG Sbjct: 442 -----ILATLEQCGGVKKRAAELLGISLKTLYNRLEEYG 475 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,262,313 Number of extensions: 1754851 Number of successful extensions: 5775 Number of sequences better than 1.0e-05: 146 Number of HSP's gapped: 5469 Number of HSP's successfully gapped: 151 Length of query: 608 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 496 Effective length of database: 25,461,023 Effective search space: 12628667408 Effective search space used: 12628667408 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 119 (50.4 bits)