BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0547.0061.p
         (160 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CC3382 [F] COG1051 ADP-ribose pyrophosphatase                          65   4e-11
DR0004 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    59   4e-09
VNG0431G [LR] COG0494 NTP pyrophosphohydrolases including oxidat...    59   4e-09
sll1537 [F] COG1051 ADP-ribose pyrophosphatase                         56   2e-08
MA3990 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    54   1e-07

>CC3382 [F] COG1051 ADP-ribose pyrophosphatase
          Length = 346

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 8/122 (6%), Positives = 25/122 (20%), Gaps = 6/122 (4%)

Query: 5   THIVAVGGIVENEQGEVLLVK----TYHGGWVFPGGQVEAGENLIEALIREIKEESGIDT 60
            +       +E     +  +                   A    +  +          +T
Sbjct: 2   QYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPET 61

Query: 61  EVSRLIGVYSNTATYKWHDGVTDVPTKVMLDYICKPVGGQLSTSDETSDSRWVAKDTALE 120
           +      V +  A +   + +       +         G          +   A   +L+
Sbjct: 62  QGLTETYVGNWLAKHGSREKLII--ASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLK 119

Query: 121 MI 122
            +
Sbjct: 120 RL 121


>DR0004 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 7/134 (5%), Positives = 20/134 (14%), Gaps = 12/134 (8%)

Query: 14  VENEQGEVLLVK------TYHGGWVFPGGQVEAGENLIEALIREIKEESGIDTEVSRLIG 67
            +  Q ++  +       T    +      V +          +    S           
Sbjct: 201 RKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYSWR--GARPQNL 258

Query: 68  V-YSNTATYKWHDGVTDVPTKVMLDYICKPVGGQLS-TSDETSDSRWVAKDT--ALEMIT 123
           V  S          +               +    +    E      +       +    
Sbjct: 259 VLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSAN 318

Query: 124 SPAIRTRFQAYLEF 137
           +             
Sbjct: 319 NEEHEAERVTGELI 332


>VNG0431G [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 11/112 (9%), Positives = 20/112 (17%), Gaps = 3/112 (2%)

Query: 17  EQGEVLLVKTYHGGWVFPGGQVEAGENLIEALIREIKEESGIDTEVSRLIGVYSNTATYK 76
                                +  G       I  +   +           V       +
Sbjct: 18  CLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKA--AREMKERVGQTLGRKE 75

Query: 77  WHDGVTDVPTKVMLDYICKPVGGQLSTSDETSDSRWVAKDTALEMITSPAIR 128
               +      + L  I K     L      S      +   L+ +T   I 
Sbjct: 76  ARGLMISTFHTLGL-DIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIE 126


>sll1537 [F] COG1051 ADP-ribose pyrophosphatase
          Length = 139

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 63/137 (45%), Gaps = 10/137 (7%)

Query: 3   MPTH--IVAVGGIVENEQGEVLLVKT--YHGGWVFPGGQVEAGENLIEALIREIKEESGI 58
           MP    +  VG +V    G VL+VKT  + G W  PGG+VE GE L  AL RE +EE G+
Sbjct: 1   MPPQFPLATVGALVTAPDGRVLIVKTTKWRGTWGVPGGKVEWGETLEAALKREFQEEVGL 60

Query: 59  DTEVSRLIGVYSNTATYKWHDGVTDVPTK-VMLDYICKPVGGQLSTSDETSDSRWVAKDT 117
           D    +   V       ++H      P   V+L+Y  +    Q+  ++E  +  WV    
Sbjct: 61  DLREIKFALVQEAVNDEQFH-----CPAHFVLLNYYARCESTQVIPNEEIVEWEWVTPLE 115

Query: 118 ALEMITSPAIRTRFQAY 134
           AL+   +   +   + Y
Sbjct: 116 ALDFPLNSFTKLLLEDY 132


>MA3990 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 13/132 (9%), Positives = 22/132 (16%), Gaps = 15/132 (11%)

Query: 6   HIVAVGGIVENEQGEVLLVK------TYHGGWVFPGGQVEAGENLIEALIREIKEESGID 59
              AV  +                  T     +  G   +A          +   E    
Sbjct: 7   QQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKER 66

Query: 60  TEVSRLIGVYSNTATYKWHDGVTDVPTKVMLDYICKPVGGQLSTSDETSDSRWVAKDTAL 119
              +                         +   I K     L      S      +   L
Sbjct: 67  VGQTLGRKEARGLMIST---------FHTLGLDIIKREYAALGMKANFSLFDDTDQLALL 117

Query: 120 EMITSPAIRTRF 131
           + +T   I    
Sbjct: 118 KELTEGLIEDDK 129


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.316    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 12,127,138
Number of extensions: 500251
Number of successful extensions: 2498
Number of sequences better than 1.0e-05: 38
Number of HSP's gapped: 2516
Number of HSP's successfully gapped: 38
Length of query: 160
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 62
Effective length of database: 27,075,699
Effective search space: 1678693338
Effective search space used: 1678693338
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 111 (47.4 bits)