BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0547.0058.p (148 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA0906 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 94 7e-20 VNG1398C [KR] COG0454 Histone acetyltransferase HPA2 and related... 76 2e-14 TM1720 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 66 2e-11 STM1720 [J] COG0009 Putative translation factor (SUA5) 66 2e-11 VC2740 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 62 4e-10 >SA0906 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 144 Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 55/142 (38%), Positives = 83/142 (58%), Gaps = 5/142 (3%) Query: 7 RVTTEEQLQMGLDIRKKVFVEEQKVPMEEEVDEYDVIGDNVHHMLLLDEGIPXXXXXXLI 66 +V ++ L+ IRKKVFVEEQ VP E E+DEY+ H++ D G P + Sbjct: 4 KVNNQKMLEDCFYIRKKVFVEEQGVPEESEIDEYE---SESIHLIGYDNGQPVATAR-IR 59 Query: 67 YYKAGTAKMQRIAVHQAYRSKGYGRVLLLALEGLAREIGFKSSILDAQCHAEDFYIKLGY 126 T K++R+AV +++R +G GR+L+ A+E LA++ GF + ++AQCHA FY L + Sbjct: 60 PINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNF 119 Query: 127 KVISLEPFYDAGILHVRMEKAL 148 K+ F + GI H+ M K L Sbjct: 120 KMRG-NIFLEEGIEHIEMTKKL 140 >VNG1398C [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 147 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 53/150 (35%), Positives = 74/150 (49%), Gaps = 11/150 (7%) Query: 5 IVRVTTEEQLQMGLDIRKKVFVEEQKVPMEEEVDEYDVIGDNVHHMLLLD------EGIP 58 ++R TT E+ + L +R VFV+EQ VP + EVD++D D H + D + Sbjct: 3 VIRATTTEEYEDALRVRFAVFVDEQGVPADMEVDDHD---DTATHFVAYDTMTGSQDATR 59 Query: 59 XXXXXXLIYYKAGTAKMQRIAVHQAYRSKGYGRVLLLALEGLAREIGFKSSILDAQCHAE 118 L Y+ K++R+AV + R G G ++ A+E ARE F L AQ Sbjct: 60 AVAAARLRAYEGSVGKVERVAVRASRRGNGVGATVMDAVEDAARER-FAELYLHAQSRVA 118 Query: 119 DFYIKLGYKVISLEPFYDAGILHVRMEKAL 148 +FY GY EPF +AGI HV M K L Sbjct: 119 EFYATRGYHREG-EPFMEAGIEHVAMRKRL 147 >TM1720 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 144 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 57/140 (40%), Positives = 82/140 (58%), Gaps = 5/140 (3%) Query: 9 TTEEQLQMGLDIRKKVFVEEQKVPMEEEVDEYDVIGDNVHHMLLLDEGIPXXXXXXLIYY 68 EE L+ L+IR+KVFVEEQ VP EEE+D D ++VH +LL EG + Sbjct: 8 NDEELLREALNIRRKVFVEEQGVPEEEELDGKD--PESVH-VLLEKEG-KFIGTARIRKI 63 Query: 69 KAGTAKMQRIAVHQAYRSKGYGRVLLLALEGLAREIGFKSSILDAQCHAEDFYIKLGYKV 128 GT K++R+A+ + R KG+GR L+ ++E G + +L+AQ +FY +LGY+ Sbjct: 64 DDGTFKIERVAILKEERRKGHGRFLMESIERELSSKGVQKIVLNAQIQVREFYERLGYRA 123 Query: 129 ISLEPFYDAGILHVRMEKAL 148 E FY+A I HVRM K + Sbjct: 124 EG-EIFYEANIPHVRMVKVV 142 >STM1720 [J] COG0009 Putative translation factor (SUA5) Length = 206 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 10/140 (7%), Positives = 29/140 (20%), Gaps = 5/140 (3%) Query: 9 TTEEQLQMGLDIRKKVFVEEQKVPMEEEVDEYDVIGDNVHHMLLLDEGIPXXXXXXLIYY 68 + Q ++ + + + + G + E + Sbjct: 8 HPDNPQQRLINQAVDIVRKGGVIVYPTDSGYAL--GCKIE-DKGAMER-ICRIRHLPDGH 63 Query: 69 KAGTAKMQRIAVHQAYRSKGYGRVLLLALEGLAREIGFKSSILDAQCHAEDFYIKLGYKV 128 + L+ K + + ++ +G +V Sbjct: 64 NFTLMCRDLSELSTYSYVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGLRV 123 Query: 129 ISLEPFYDAGILHVRMEKAL 148 S P A + + Sbjct: 124 PS-NPIALALLDTLGEPMLS 142 >VC2740 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 310 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 5/125 (4%) Query: 4 EIVRVTTEEQLQMGLDIRKKVFVEEQKVPMEEEVDEYDVIGDNVHHMLLLDE-GIPXXXX 62 +++ TT+ QL R ++ E ++P+ E DEYD + HH +++D G P Sbjct: 5 KLITPTTDNQLNKYFHFRWQMLREPWRMPIGSERDEYDSMS---HHRMIVDSRGYPMAIG 61 Query: 63 XXLIYYKAGTAKMQRIAVHQAYRSKGYGRVLLLALEGLAREIGFKSSILDAQCHAEDFYI 122 I +++ +AV RSKG G ++L+ALE LAR+ G K + +A+ A FY Sbjct: 62 RLYITPDC-EGQIRYMAVKANRRSKGMGSLILVALESLARQEGAKRLVCNAREDAIPFYA 120 Query: 123 KLGYK 127 K G++ Sbjct: 121 KNGFE 125 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.140 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 10,004,594 Number of extensions: 345659 Number of successful extensions: 671 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 671 Number of HSP's successfully gapped: 7 Length of query: 148 Length of database: 38,378,431 Length adjustment: 97 Effective length of query: 51 Effective length of database: 27,191,033 Effective search space: 1386742683 Effective search space used: 1386742683 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 110 (47.0 bits)