BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0547.0055.p
         (192 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sll0647 [R] COG1234 Metal-dependent hydrolases of the beta-lacta...    79   3e-15
CAC0364 [R] COG1234 Metal-dependent hydrolases of the beta-lacta...    52   8e-07

>sll0647 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III
          Length = 256

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 55/194 (28%), Positives = 93/194 (47%), Gaps = 13/194 (6%)

Query: 1   MTIYLQMLGTGDAFST--KYYNNNAVLQ-DHGYTLLIDCGVTAPQAIKALGKSFQEVTET 57
           M   L  LG+G AF+     + +NA+L  D+G   LIDCG     ++ ALG S +++T+ 
Sbjct: 1   MAANLTFLGSGSAFTVGADNFQSNAILTLDNGKKFLIDCGTDIRFSLYALGLSHRDITDI 60

Query: 58  LITHIHGDHIGGLAELAGTPSQEPH-GKMTLLLAETLIEPLWQHPLLEPLHR-KGDSRSL 115
            ++H+H DH+GGL  +  +   +P+ GK  L L++ +   LW+  L   +   +G    +
Sbjct: 61  YVSHLHSDHVGGLEYVGFSTMFDPNCGKPNLYLSQDIAADLWERSLAGGMEAIEGGMTEV 120

Query: 116 ADVFNVKPLKPDTPYTLSPSLTLELIRTPH-------MPGKASYSLLLNECVFYSADLTF 168
              F +  L P   +T   ++  +LI+  H       MP    +  + +  VF+S D  F
Sbjct: 121 DSYFQIHALGPGETFTWE-NVNFQLIKLNHVDTGSMLMPAYGLFFTVNHFQVFFSNDTKF 179

Query: 169 QPELLLHLVHNRGI 182
             + L    H   I
Sbjct: 180 SYDRLQEYFHRADI 193


>CAC0364 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase
           superfamily III
          Length = 252

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 9/183 (4%), Positives = 24/183 (13%), Gaps = 37/183 (20%)

Query: 5   LQMLGTGDAFSTKYYNNNAVLQDHGYTLLIDCGVTAPQAIKALGKSFQEVTE--TLITHI 62
                +     +   +  AV       L     V           +              
Sbjct: 2   SDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGN-STALLQQRWPAARITG 60

Query: 63  HGDHIGGLAELAGTPSQEPHGKMTLLLAETLIEPLWQHPLLEPLHRKGDSRSLADVFNV- 121
                  +AE                +   +                       D+    
Sbjct: 61  IDSSPAMIAEAR------SALPDCQFVEADIRNW--------------QPVQALDLIFAN 100

Query: 122 ------KPLKPDTPYTLSP----SLTLELIRTPHMPGKASYSLLL---NECVFYSADLTF 168
                        P+ +S      +    +    +         +           +   
Sbjct: 101 ASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA 160

Query: 169 QPE 171
              
Sbjct: 161 GVH 163


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.319    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 14,653,637
Number of extensions: 561519
Number of successful extensions: 1205
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 1222
Number of HSP's successfully gapped: 2
Length of query: 192
Length of database: 38,378,431
Length adjustment: 101
Effective length of query: 91
Effective length of database: 26,729,697
Effective search space: 2432402427
Effective search space used: 2432402427
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 113 (48.1 bits)